[go: up one dir, main page]

FI873060L - Modifierad vaevnads-plasmin-aktivator. - Google Patents

Modifierad vaevnads-plasmin-aktivator. Download PDF

Info

Publication number
FI873060L
FI873060L FI873060A FI873060A FI873060L FI 873060 L FI873060 L FI 873060L FI 873060 A FI873060 A FI 873060A FI 873060 A FI873060 A FI 873060A FI 873060 L FI873060 L FI 873060L
Authority
FI
Finland
Prior art keywords
vaevnads
modifierad
plasmin activator
plasmin
activator
Prior art date
Application number
FI873060A
Other languages
English (en)
Other versions
FI873060A7 (fi
FI873060A0 (fi
Inventor
Per Bruno Wallen
Bo Anders Norrman
Bjorn Andersen Nexo
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri As filed Critical Novo Industri As
Publication of FI873060A0 publication Critical patent/FI873060A0/fi
Publication of FI873060A7 publication Critical patent/FI873060A7/fi
Publication of FI873060L publication Critical patent/FI873060L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6456Plasminogen activators
    • C12N9/6459Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21069Protein C activated (3.4.21.69)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
FI873060A 1986-07-11 1987-07-10 Modifierad vaevnads-plasmin-aktivator. FI873060L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88435786A 1986-07-11 1986-07-11

Publications (3)

Publication Number Publication Date
FI873060A0 FI873060A0 (fi) 1987-07-10
FI873060A7 FI873060A7 (fi) 1988-01-12
FI873060L true FI873060L (fi) 1988-01-12

Family

ID=25384445

Family Applications (1)

Application Number Title Priority Date Filing Date
FI873060A FI873060L (fi) 1986-07-11 1987-07-10 Modifierad vaevnads-plasmin-aktivator.

Country Status (5)

Country Link
EP (1) EP0253582A1 (fi)
JP (1) JPS63119675A (fi)
DK (1) DK345087A (fi)
FI (1) FI873060L (fi)
NO (1) NO872875L (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5108909A (en) * 1985-03-22 1992-04-28 Chiron Corporation Expression of TPA in mammalian cells
DK623186A (da) * 1985-12-23 1987-08-26 Chiron Corp Polypeptid med vaevsplasminogen-aktivator-virkning
SE8702562L (sv) * 1987-06-18 1988-12-19 Kabigen Ab Nya fibrinolytiska enzymer
DK395288D0 (da) * 1988-07-15 1988-07-15 Novo Industri As Proteiner
US5714145A (en) * 1988-09-02 1998-02-03 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties
US5262170A (en) * 1988-09-02 1993-11-16 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties and substituted at amino acid positions 296-299, DNA molecules encoding them, vectors, and host cells
US5108901A (en) * 1988-09-02 1992-04-28 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties
NZ253556A (en) * 1992-06-03 1995-11-27 Genentech Inc Tissue plasminogen activator (t-pa) variants (with extended circulatory half-life and/or potency); preparation, compositions, host cells, dna sequences, and expression vehicles thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL68561A (en) * 1982-05-05 1991-01-31 Genentech Inc Preparation of polypeptide with human tissue plasminogen activator function,processes for making it,and dna and transformed cell intermediates thereof
US4753879A (en) * 1984-08-27 1988-06-28 Biogen N.V. Modified tissue plasminogen activators

Also Published As

Publication number Publication date
FI873060A7 (fi) 1988-01-12
NO872875L (no) 1988-01-12
NO872875D0 (no) 1987-07-10
FI873060A0 (fi) 1987-07-10
DK345087A (da) 1988-01-12
AU608232B2 (en) 1991-03-28
DK345087D0 (da) 1987-07-06
AU7554687A (en) 1988-01-14
JPS63119675A (ja) 1988-05-24
EP0253582A1 (en) 1988-01-20

Similar Documents

Publication Publication Date Title
DE69012888D1 (de) Plasminogenaktivator.
DE3771128D1 (de) Kuehlschrank.
FI870419A0 (fi) Stoedsubstans foer anvaendning i detergentkompositionen.
DE3750963D1 (de) Reflektometer.
DE3676760D1 (de) Poly-kringle-plasminogenaktivator.
FI870082A7 (fi) Munstycksarrangemang i tvao delar foer skummedel.
NO893535D0 (no) Vaskemiddelblanding.
FI873581A0 (fi) Fast stoedanordning.
NO911234L (no) Innsmekkbar aktivatorhendel.
FI893833A7 (fi) Rekombinant aktivator foer naturliga doedarceller.
FI880541A0 (fi) Homogena haordplastkopolymerer.
FI861117A7 (fi) Genomfoerningskonstruktion i en maetanordning.
DE3766420D1 (de) Bestimmte 3-benzoyl-3-oxolactame.
FI873060L (fi) Modifierad vaevnads-plasmin-aktivator.
NO872506L (no) Elastomer-polyolefin-blandinger.
NO166102C (no) Ettergivende torsjonshylse.
FI883943A0 (fi) Modifierade plasminogen-aktivatorer.
FI873879L (fi) Lymfocyter aktiverande polypeptider.
FI861940A0 (fi) Stoedanordning foer nackstycket i en borrmaskin.
FI875642L (fi) Foerfarande foer framstaellning av plasminogenaktivatorer i prokaryoter.
DE3777385D1 (de) Alpha-acyloxyketon-derivate.
ATE59857T1 (de) Poly-kringle-plasminogenaktivator.
NO944962L (no) Aktivator
IT211200Z2 (it) Smolly - portachiavi...morbido.
FI864667A7 (fi) Sprutmetod och -munstycke foer armerad plast.

Legal Events

Date Code Title Description
FA Application withdrawn [patent]

Owner name: NOVO NORDISK A/S