FI872864L - Menetelmä farmaseuttisesti aktiivisten bentsimidatsolijohdannaisten valmistamiseksi - Google Patents

Menetelmä farmaseuttisesti aktiivisten bentsimidatsolijohdannaisten valmistamiseksi Download PDF

Info

Publication number: FI872864L
Authority: FI; Finland
Prior art keywords: preparation; pharmaceutically active; benzimidazole derivatives; active benzimidazole; derivatives
Prior art date: 1985-10-29

Application number

FI872864A

Other languages

English (en)

Swedish (sv)

Other versions

FI872864A0 (fi

FI91151C (fi

FI91151B (fi

Inventor

Tomas Boerje Alminger

Haokan Sigurd Larsson

Per Lennart Lindberg

Gunnel Elisabeth Sunden

Original Assignee

Haessle Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-10-29

Filing date

1987-06-29

Publication date

1987-06-29

1987-06-29 Application filed by Haessle Ab filed Critical Haessle Ab

1987-06-29 Publication of FI872864L publication Critical patent/FI872864L/fi

1987-06-29 Publication of FI872864A0 publication Critical patent/FI872864A0/fi

1994-02-15 Application granted granted Critical

1994-02-15 Publication of FI91151B publication Critical patent/FI91151B/fi

1994-05-25 Publication of FI91151C publication Critical patent/FI91151C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Indole Compounds (AREA)

FI872864A 1985-10-29 1987-06-29 Menetelmä farmaseuttisesti aktiivisten bentsimidatsolijohdannaisten valmistamiseksi FI91151C (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
SE8505112A SE8505112D0 (sv)	1985-10-29	1985-10-29	Novel pharmacological compounds
SE8505112		1985-10-29
PCT/SE1986/000493 WO1987002668A1 (en)	1985-10-29	1986-10-28	Novel pharmacological compounds
SE8600493		1986-10-28

Publications (4)

Publication Number	Publication Date
FI872864L true FI872864L (fi)	1987-06-29
FI872864A0 FI872864A0 (fi)	1987-06-29
FI91151B FI91151B (fi)	1994-02-15
FI91151C FI91151C (fi)	1994-05-25

Family

ID=20361960

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI872864A FI91151C (fi)	1985-10-29	1987-06-29	Menetelmä farmaseuttisesti aktiivisten bentsimidatsolijohdannaisten valmistamiseksi

Country Status (31)

Country	Link
US (1)	US5021433A (fi)
EP (2)	EP0221041A3 (fi)
JP (2)	JPH0780874B2 (fi)
KR (1)	KR950009858B1 (fi)
CN (1)	CN1022487C (fi)
AT (1)	ATE79619T1 (fi)
AU (1)	AU598491B2 (fi)
CS (1)	CS272767B2 (fi)
DD (1)	DD252375A5 (fi)
DE (1)	DE3686483T2 (fi)
DK (1)	DK320587D0 (fi)
EG (1)	EG17753A (fi)
ES (1)	ES2051696T3 (fi)
FI (1)	FI91151C (fi)
GR (1)	GR3006177T3 (fi)
HU (1)	HU198474B (fi)
IE (1)	IE59167B1 (fi)
IL (1)	IL80437A0 (fi)
IS (1)	IS1564B (fi)
JO (1)	JO1502B1 (fi)
LT (1)	LTIP1681A (fi)
LV (1)	LV10270B (fi)
MY (1)	MY101791A (fi)
NO (1)	NO171365C (fi)
NZ (1)	NZ218028A (fi)
PH (1)	PH25319A (fi)
PL (1)	PL150240B1 (fi)
PT (1)	PT83647B (fi)
SE (1)	SE8505112D0 (fi)
WO (1)	WO1987002668A1 (fi)
ZA (1)	ZA867716B (fi)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ234564A (en) *	1986-11-21	1991-04-26	Haessle Ab	1-substituted benzimidazoles and pharmaceutical compositions
EP0436025A4 (en) *	1988-09-20	1991-09-11	Hisamitsu Pharmaceutical Co. Inc.	Novel dibenz b,e)oxepin derivatives
EG19302A (en) *	1988-12-22	1994-11-30	Haessle Ab	Compound with gastric acid inhibitory effect and process for its preparation
SE8804629D0 (sv) *	1988-12-22	1988-12-22	Ab Haessle	New therapeutically active compounds
US4965269A (en) *	1989-12-20	1990-10-23	Ab Hassle	Therapeutically active chloro substituted benzimidazoles
US5274099A (en) *	1989-12-20	1993-12-28	Aktiebolaget Hassle	Therapeutically active fluoro substituted benzimidazoles
US5049674A (en) *	1989-12-20	1991-09-17	Aktiebolaget Hassle	Therapeutically active fluoro substituted benzimidazoles
SE9002206D0 (sv)	1990-06-20	1990-06-20	Haessle Ab	New compounds
AU649456B2 (en) *	1990-06-20	1994-05-26	Astra Aktiebolag	Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use
ES2048109B1 (es) *	1992-07-20	1994-12-16	Espanola Prod Quimicos	Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol.
WO1995032957A1 (en) *	1994-05-27	1995-12-07	Astra Aktiebolag	Novel ethoxycarbonyloxymethyl derivatives of substituted benzimidazoles
US6093734A (en) *	1998-08-10	2000-07-25	Partnership Of Michael E. Garst, George Sachs, And Jai Moo Shin	Prodrugs of proton pump inhibitors
HRP20010106A2 (en)	1998-08-10	2002-02-28	Partnership Of Michael E Garst	Prodrugs of proton pump inhibitors
US6852739B1 (en)	1999-02-26	2005-02-08	Nitromed Inc.	Methods using proton pump inhibitors and nitric oxide donors
US6369087B1 (en) *	1999-08-26	2002-04-09	Robert R. Whittle	Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
WO2002030920A1 (en) *	2000-10-12	2002-04-18	Takeda Chemical Industries, Ltd.	Benzimidazole compounds, process for producing the same and use thereof
EP1437352A4 (en) *	2001-09-25	2004-12-08	Takeda Chemical Industries Ltd	BENZIMIDAZOLE COMPOUND, METHOD FOR THE PRODUCTION AND USE THEREOF
US7410981B2 (en) *	2002-06-14	2008-08-12	Takeda Pharmaceutical Company Limited	Prodrugs of imidazole derivatives, for use as proton pump inhibitors in the treatment of e.g. peptic ulcers
PL375255A1 (en) *	2002-07-19	2005-11-28	Winston Pharmaceuticals Llc	Prodrugs of proton pump inhibitors
WO2004012659A2 (en)	2002-08-01	2004-02-12	Nitromed, Inc.	Nitrosated proton pump inhibitors, compositions and methods of use
MY148805A (en)	2002-10-16	2013-05-31	Takeda Pharmaceutical	Controlled release preparation
US8802139B2 (en) *	2003-06-26	2014-08-12	Intellipharmaceutics Corp.	Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
WO2005039640A1 (en) *	2003-10-03	2005-05-06	Allergan Inc.	Compositions comprising trefoil factor family peptides and/or mucoadhesives and proton pump inhibitor prodrugs
US20050075371A1 (en) *	2003-10-03	2005-04-07	Allergan, Inc.	Methods and compositions for the oral administration of prodrugs of proton pump inhibitors
JP2007523164A (ja) *	2004-02-18	2007-08-16	アラーガン、インコーポレイテッド	プロトンポンプインヒビターに関連する化合物の静脈内投与のための方法および組成物
CA2556756A1 (en) *	2004-02-18	2005-09-09	Allergan, Inc.	Compositions comprising prodrugs of proton pump inhibitors
WO2005117870A2 (en) *	2004-04-16	2005-12-15	Santarus, Inc.	Combination of proton pump inhibitor, buffering agent, and prokinetic agent
ATE437869T1 (de) *	2004-04-28	2009-08-15	Hetero Drugs Ltd	Verfahren zur herstellung von pyridinylmethyl-1h- benzimidazolverbindungen in enantiomerenangereicherter form oder als einzelne enantiomere
US7365206B2 (en)	2004-05-28	2008-04-29	Hetero Drugs Limited	Stereoselective synthesis of benzimidazole sulfoxides
US8394409B2 (en) *	2004-07-01	2013-03-12	Intellipharmaceutics Corp.	Controlled extended drug release technology
US10624858B2 (en)	2004-08-23	2020-04-21	Intellipharmaceutics Corp	Controlled release composition using transition coating, and method of preparing same
US10064828B1 (en)	2005-12-23	2018-09-04	Intellipharmaceutics Corp.	Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
US9561188B2 (en) *	2006-04-03	2017-02-07	Intellipharmaceutics Corporation	Controlled release delivery device comprising an organosol coat
US10960077B2 (en)	2006-05-12	2021-03-30	Intellipharmaceutics Corp.	Abuse and alcohol resistant drug composition
WO2008036201A1 (en) *	2006-09-19	2008-03-27	Alevium Pharmaceuticals, Inc.	Prodrugs of proton pump inhibitors including the 1h-imidazo[4,5-b] pyridine moiety
WO2008057802A2 (en)	2006-10-27	2008-05-15	The Curators Of The University Of Missouri	Compositions comprising at least one acid labile proton pump inhibiting agents, optionally other pharmaceutically active agents and methods of using same
US20080194307A1 (en) *	2007-02-13	2008-08-14	Jeff Sanger	Sports-based game of chance
US8247440B2 (en)	2008-02-20	2012-08-21	Curators Of The University Of Missouri	Composition comprising omeprazole, lansoprazole and at least one buffering agent
AU2010339691B2 (en) *	2010-01-07	2015-04-02	Alkermes Pharma Ireland Limited	Prodrugs of heteraromatic compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4045564A (en) *	1974-02-18	1977-08-30	Ab Hassle	Benzimidazole derivatives useful as gastric acid secretion inhibitors
SE418966B (sv) *	1974-02-18	1981-07-06	Haessle Ab	Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) *	1974-05-16	1981-01-26	Haessle Ab	Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (fi) *	1977-09-19	1981-07-25	Hoffmann La Roche
SE7804231L (sv) *	1978-04-14	1979-10-15	Haessle Ab	Magsyrasekretionsmedel
US4359465A (en) *	1980-07-28	1982-11-16	The Upjohn Company	Methods for treating gastrointestinal inflammation
CH644116A5 (de) *	1980-08-21	1984-07-13	Hoffmann La Roche	Imidazolderivate.
SE8300736D0 (sv) *	1983-02-11	1983-02-11	Haessle Ab	Novel pharmacologically active compounds
IL75400A (en) *	1984-06-16	1988-10-31	Byk Gulden Lomberg Chem Fab	Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
AU568441B2 (en) *	1984-09-24	1987-12-24	Upjohn Company, The	2-(pyridylalkenesulfinyl) benzimidazole derivatives
ZA856671B (en) *	1984-09-24	1986-04-30	Upjohn Co	N-substituted derivatives of 2-(pyridylaklenesulfinyl)benzimidazoles as gastric antisecretory agents

1985
- 1985-10-29 SE SE8505112A patent/SE8505112D0/xx unknown
1986
- 1986-10-09 ZA ZA867716A patent/ZA867716B/xx unknown
- 1986-10-22 EG EG661/86A patent/EG17753A/xx active
- 1986-10-22 NZ NZ218028A patent/NZ218028A/xx unknown
- 1986-10-23 IE IE280586A patent/IE59167B1/en not_active IP Right Cessation
- 1986-10-24 PH PH34408A patent/PH25319A/en unknown
- 1986-10-27 MY MYPI86000038A patent/MY101791A/en unknown
- 1986-10-27 DD DD86295633A patent/DD252375A5/de not_active IP Right Cessation
- 1986-10-27 JO JO19861502A patent/JO1502B1/en active
- 1986-10-28 EP EP86850378A patent/EP0221041A3/en active Pending
- 1986-10-28 HU HU865443A patent/HU198474B/hu not_active IP Right Cessation
- 1986-10-28 WO PCT/SE1986/000493 patent/WO1987002668A1/en not_active Ceased
- 1986-10-28 AT AT86906498T patent/ATE79619T1/de not_active IP Right Cessation
- 1986-10-28 KR KR1019870700555A patent/KR950009858B1/ko not_active Expired - Lifetime
- 1986-10-28 IL IL80437A patent/IL80437A0/xx not_active IP Right Cessation
- 1986-10-28 EP EP86906498A patent/EP0233284B1/en not_active Expired - Lifetime
- 1986-10-28 IS IS3156A patent/IS1564B/is unknown
- 1986-10-28 AU AU65429/86A patent/AU598491B2/en not_active Ceased
- 1986-10-28 JP JP61505700A patent/JPH0780874B2/ja not_active Expired - Lifetime
- 1986-10-28 DE DE8686906498T patent/DE3686483T2/de not_active Expired - Fee Related
- 1986-10-28 ES ES86906498T patent/ES2051696T3/es not_active Expired - Lifetime
- 1986-10-29 PT PT83647A patent/PT83647B/pt not_active IP Right Cessation
- 1986-10-29 CS CS782686A patent/CS272767B2/cs unknown
- 1986-10-29 CN CN86107595A patent/CN1022487C/zh not_active Expired - Lifetime
- 1986-10-29 PL PL1986262105A patent/PL150240B1/pl unknown
1987
- 1987-06-24 DK DK320587A patent/DK320587D0/da not_active Application Discontinuation
- 1987-06-26 NO NO872686A patent/NO171365C/no unknown
- 1987-06-29 FI FI872864A patent/FI91151C/fi not_active IP Right Cessation
1988
- 1988-05-12 US US07/195,343 patent/US5021433A/en not_active Expired - Fee Related
1992
- 1992-11-05 GR GR920402498T patent/GR3006177T3/el unknown
1993
- 1993-06-30 LV LVP-93-856A patent/LV10270B/xx unknown
- 1993-12-28 LT LTIP1681A patent/LTIP1681A/xx not_active Application Discontinuation
1994
- 1994-12-21 JP JP6318132A patent/JPH0826014B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DK320587A (da)	1987-06-24
NO171365C (no)	1993-03-03
AU598491B2 (en)	1990-06-28
CN86107595A (zh)	1987-07-08
LV10270A (lv)	1994-10-20
CS782686A2 (en)	1990-05-14
PH25319A (fi)	1991-04-30
ES2051696T3 (es)	1994-07-01
PL150240B1 (en)	1990-05-31
NO872686D0 (no)	1987-06-26
PL262105A1 (en)	1988-08-18
FI872864A0 (fi)	1987-06-29
FI91151C (fi)	1994-05-25
IE59167B1 (en)	1994-01-12
EP0221041A3 (en)	1987-10-28
EP0221041A2 (en)	1987-05-06
JPH07188216A (ja)	1995-07-25
LTIP1681A (en)	1995-09-25
HU198474B (en)	1989-10-30
NO171365B (no)	1992-11-23
WO1987002668A1 (en)	1987-05-07
IE862805L (en)	1987-04-29
CN1022487C (zh)	1993-10-20
LV10270B (en)	1995-04-20
CS272767B2 (en)	1991-02-12
JO1502B1 (en)	1989-01-25
FI91151B (fi)	1994-02-15
KR950009858B1 (ko)	1995-08-29
ATE79619T1 (de)	1992-09-15
PT83647A (en)	1986-11-01
MY101791A (en)	1992-01-31
JPH0826014B2 (ja)	1996-03-13
IS1564B (is)	1994-12-13
US5021433A (en)	1991-06-04
EG17753A (en)	1991-12-30
EP0233284A1 (en)	1987-08-26
AU6542986A (en)	1987-05-19
PT83647B (pt)	1989-05-31
JPH0780874B2 (ja)	1995-08-30
KR870700620A (ko)	1987-12-30
HUT43843A (en)	1987-12-28
SE8505112D0 (sv)	1985-10-29
DE3686483T2 (de)	1993-02-04
NZ218028A (en)	1990-02-26
IL80437A0 (en)	1987-01-30
EP0233284B1 (en)	1992-08-19
DK320587D0 (da)	1987-06-24
JPS63501151A (ja)	1988-04-28
ZA867716B (en)	1987-05-27
DD252375A5 (de)	1987-12-16
IS3156A7 (is)	1987-04-30
NO872686L (no)	1987-06-26
DE3686483D1 (de)	1992-09-24
GR3006177T3 (fi)	1993-06-21

Publication	Publication Date	Title
FI872864L (fi)	1987-06-29	Menetelmä farmaseuttisesti aktiivisten bentsimidatsolijohdannaisten valmistamiseksi
FI91152B (fi)	1994-02-15	Menetelmä terapeuttisesti aktiivisten bentsimidatsolijohdannaisten valmistamiseksi
FI890508L (fi)	1989-02-02	Menetelmä farmaseuttisesti aktiivisten 3-indolipalorypälehappojohdannaisten valmistamiseksi
FI96861C (fi)	1996-09-10	Menetelmä terapeuttisesti aktiivisten substituoitujen indolyylipyrrolijohdannaisten valmistamiseksi
FI883739A7 (fi)	1989-02-15	Menetelmä terapeuttisesti aktiivisten fenoksi-indaanimetyyliamiinijohdannaisten valmistamiseksi
NO864126D0 (no)	1986-10-16	Fremgangsmaate for fremstilling av terapeutisk aktive pyridon-derivater.
NO173545C (no)	1993-12-29	Analogifremgangsmaate for fremstilling av terapeutisk aktive kinazolinderivater
FI875229A0 (fi)	1987-11-27	Menetelmä uusien farmakologisesti aktiivisten katekolijohdoksien valmistamiseksi
FI875660L (fi)	1987-12-22	Menetelmä terapeuttisesti käyttökelpoisten 5-fenyyli-2-pyrimidinonijohdannaisten valmistamiseksi
NO170480C (no)	1992-10-21	Analogifremgangsmaate for fremstilling av terapeutisk aktive fenoksyeddiksyre-derivater
FI875024A7 (fi)	1988-05-15	Menetelmä terapeuttisesti käyttökelpoisten 1-alkyyli-6-halogeenitetrahydronaftaleenijohdannaisten valmistamiseksi
FI891361A7 (fi)	1989-09-26	Menetelmä farmaseuttisesti vaikuttavien aryylihydratsonien valmistamiseksi
NO864425L (no)	1987-05-08	Fremgangsmaate for fremstilling av terapeutisk aktive heterocyklyl-oksoftalazinyl-eddiksyre-derivater
NO173442C (no)	1993-12-15	Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidinderivater
FI890072A0 (fi)	1989-01-06	Menetelmä farmaseuttisesti käyttökelpoisten isokinoliinijohdannaisten valmistamiseksi
FI853649A7 (fi)	1986-03-25	Menetelmä farmaseuttisesti aktiivisten 2-(pyridyylialkeenisulfinyyli)bentsimidatsolien valmistamiseksi.
NO167026C (no)	1991-09-25	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater
FI95570C (fi)	1996-02-26	Menetelmä lääkinnällisesti vaikuttavien pyridatsinoni-3(2H)-onijohdannaisten valmistamiseksi
NO167916C (no)	1991-12-27	Analogifremgangsmaate for fremstilling av terapeutisk aktive tiolaktam-n-eddiksyrederivater
FI96601C (fi)	1996-07-25	Menetelmä terapeuttisesti aktiivisten tetratsolijohdannaisten valmistamiseksi
NO854369L (no)	1986-05-05	Fremgangsmaate for fremstilling av terapeutisk aktive benzimidazol-derivater
NO171592C (no)	1993-04-07	Fremgangsmaate for fremstilling av aktive cinnolin-derivater
FI823336A7 (fi)	1983-04-02	Menetelmä farmaseuttisesti aktiivisten bentsamidijohdannaisten valmistamiseksi.
FI871087A7 (fi)	1987-09-15	Menetelmä terapeuttisesti aktiivisten 1,2,3,4-tetrahydro-3-karbamoyyli-2-tiokso/okso-5-pyrimidiinikarboksyylihappojohdannaisten valmistamiseksi
FI882909A7 (fi)	1988-12-20	Menetelmä uusien, terapeuttisesti käyttökelpoisten furanyylimetyylisubstituoitujen bentsimidatsoli- ja imidatsopyridiinijohdannaisten valmistamiseksi

Legal Events

Date	Code	Title	Description
1994-01-17	BB	Publication of examined application
1997-05-07	MM	Patent lapsed
2004-08-31	MM	Patent lapsed	Owner name: AKTIEBOLAGET HAESSLE