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FI865336L - Foerfarande foer framstaellning av en snabbt framstaellbar homogen mikrokapselsuspension. - Google Patents

Foerfarande foer framstaellning av en snabbt framstaellbar homogen mikrokapselsuspension. Download PDF

Info

Publication number
FI865336L
FI865336L FI865336A FI865336A FI865336L FI 865336 L FI865336 L FI 865336L FI 865336 A FI865336 A FI 865336A FI 865336 A FI865336 A FI 865336A FI 865336 L FI865336 L FI 865336L
Authority
FI
Finland
Prior art keywords
framstaellbar
snabbt
homogen
foerfarande foer
microcapsule suspension
Prior art date
Application number
FI865336A
Other languages
English (en)
Other versions
FI86596B (fi
FI865336A0 (fi
FI86596C (fi
Inventor
Massimo Calanchi
Leonardo Gentilini
Marco Marconi
Original Assignee
Eurand Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurand Spa filed Critical Eurand Spa
Publication of FI865336A0 publication Critical patent/FI865336A0/fi
Publication of FI865336L publication Critical patent/FI865336L/fi
Publication of FI86596B publication Critical patent/FI86596B/fi
Application granted granted Critical
Publication of FI86596C publication Critical patent/FI86596C/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A61K9/5057—Gelatin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2989—Microcapsule with solid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI865336A 1985-05-08 1986-12-30 Foerfarande foer framstaellning av en snabbt framstaellbar homogen mikrokapselsuspension. FI86596C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IT2061785 1985-05-08
IT20617/85A IT1183574B (it) 1985-05-08 1985-05-08 Metodo per ottenere una sospensione estemporanea omogenea di microcapsule
EP8600280 1986-05-02
PCT/EP1986/000280 WO1986006626A1 (en) 1985-05-08 1986-05-02 Method of preparing an extemporaneous homogeneous microcapsule suspension

Publications (4)

Publication Number Publication Date
FI865336A0 FI865336A0 (fi) 1986-12-30
FI865336L true FI865336L (fi) 1986-12-30
FI86596B FI86596B (fi) 1992-06-15
FI86596C FI86596C (fi) 1992-09-25

Family

ID=11169617

Family Applications (1)

Application Number Title Priority Date Filing Date
FI865336A FI86596C (fi) 1985-05-08 1986-12-30 Foerfarande foer framstaellning av en snabbt framstaellbar homogen mikrokapselsuspension.

Country Status (19)

Country Link
US (1) US5008117A (fi)
EP (1) EP0222856B1 (fi)
JP (1) JP2609597B2 (fi)
KR (1) KR900000212B1 (fi)
AT (1) ATE59287T1 (fi)
AU (1) AU589644B2 (fi)
CA (1) CA1274144A (fi)
DE (1) DE3676642D1 (fi)
DK (1) DK157730C (fi)
ES (1) ES8707103A1 (fi)
FI (1) FI86596C (fi)
HU (1) HUT44168A (fi)
IT (1) IT1183574B (fi)
NO (1) NO171949C (fi)
NZ (1) NZ216062A (fi)
PT (1) PT82541B (fi)
RU (1) RU2059409C1 (fi)
WO (1) WO1986006626A1 (fi)
ZA (1) ZA863399B (fi)

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GB8628359D0 (en) * 1986-11-27 1986-12-31 Zyma Sa Galenical formulation
GB8702411D0 (en) * 1987-02-03 1987-03-11 Zyma Sa Swellable pellets
US5064650A (en) * 1988-04-19 1991-11-12 Southwest Research Institute Controlled-release salt sensitive capsule for oral use and adhesive system
EP0407464A1 (en) * 1988-04-19 1991-01-16 Southwest Research Institute Controlled release of active ingredients from capsules having a salt sensitive shell material
FR2634376B1 (fr) 1988-07-21 1992-04-17 Farmalyoc Nouvelle forme unitaire, solide et poreuse comprenant des microparticules et/ou des nanoparticules, ainsi que sa preparation
NZ234143A (en) * 1989-06-28 1991-10-25 Mcneil Ppc Inc Aqueous pharmaceutical suspension formulation for administering substantially insoluble pharmaceutical agents
US5112604A (en) * 1989-09-01 1992-05-12 Riker Laboratories, Inc. Oral suspension formulation
IT1246350B (it) * 1990-07-11 1994-11-17 Eurand Int Metodo per ottenere una rapida sospensione in acqua di farmaci insolubili
US5300302A (en) * 1990-10-04 1994-04-05 Nestec S.A. Pharmaceutical composition in gel form in a dispensing package
US5252337A (en) * 1991-06-25 1993-10-12 Eurand America, Inc. Controlled release calcium channel blocker microcapsules
US5599556A (en) * 1991-12-31 1997-02-04 Abbott Laboratories Prolamine coatings for taste masking
US5272137A (en) * 1992-02-14 1993-12-21 Mcneil-Pfc, Inc. Aqueous pharmaceutical suspension for pharmaceutical actives
MX9301823A (es) * 1992-03-30 1994-01-31 Alza Corp Composicion para el suministro de liberacion controlado de un agente biologicamente activo.
WO1993020134A1 (en) * 1992-03-30 1993-10-14 Alza Corporation Additives for bioerodible polymers to regulate degradation
EP0642344B1 (en) * 1992-04-30 1997-03-19 Schering Corporation Stable hydrated cephalosporin dry powder for oral suspension formulation
US5422122A (en) * 1992-08-04 1995-06-06 Eurand America, Incorporated Controlled release potassium chloride tablet
US5981719A (en) 1993-03-09 1999-11-09 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
NO941358L (no) * 1993-04-16 1994-10-17 Mcneil Ppc Inc Vandig farmasöytisk suspensjon og fremgangsmåte for fremstilling derav
GB2318511A (en) * 1996-10-23 1998-04-29 Eurand Int Process for the preparation of a pharmaceutical composition for rapid suspension in water
RU2147923C1 (ru) * 1997-12-02 2000-04-27 Ивановский государственный университет Способ получения микрокапсул
UA65607C2 (uk) * 1998-03-04 2004-04-15 Орто-Макнейл Фармацевтикал, Інк. Фармацевтична композиція (варіанти) та спосіб її приготування
GB9822170D0 (en) * 1998-10-13 1998-12-02 Danbioyst Uk Ltd Novel formulations of fexofenadine
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6432448B1 (en) 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6159491A (en) * 1999-02-12 2000-12-12 Biovector Technologies, Inc. Prolonged release bioadhesive vaginal gel dosage form
US6500462B1 (en) * 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
US6699315B2 (en) 2000-11-28 2004-03-02 Fmc Corporation Edible PGA coating composition
US6932861B2 (en) * 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
CN1487935A (zh) * 2000-12-11 2004-04-07 ����ҩƷ��ҵ��ʽ���� 改良型水溶性药物组合物
JP2004168703A (ja) * 2002-11-20 2004-06-17 Shin Etsu Chem Co Ltd マイクロカプセル及びその製造方法
US20040170686A1 (en) * 2003-01-31 2004-09-02 Fredrickson Jennifer K. Suspension vehicle for coated drug particles
US20040191326A1 (en) * 2003-03-31 2004-09-30 Reo Joseph P. Taste-masking vehicle for coated oxazolidinone particles
US7632521B2 (en) * 2003-07-15 2009-12-15 Eurand, Inc. Controlled release potassium chloride tablets
US20050118194A1 (en) * 2003-12-01 2005-06-02 Sin Yoke M. Oral vaccine, method for its preparation and use thereof
US20060134210A1 (en) * 2004-12-22 2006-06-22 Astrazeneca Ab Solid dosage form comprising proton pump inhibitor and suspension made thereof
EP3568122B1 (en) * 2017-01-10 2023-10-04 Dukebox SP. Z O.O. A method of manufacturing a suspension of nanoparticles of potassium salt or magnesium salt
PL3927322T3 (pl) * 2019-02-22 2024-02-05 Catalent U.K. Swindon Zydis Limited Minimalizacja napowietrzania zawiesin podczas mieszania typu in-line
PL3927314T3 (pl) 2019-02-22 2024-02-19 Catalent U.K. Swindon Zydis Limited Minimalizacja aglomeracji materiału powlekającego cząstki leku podczas przechowywania dla ustabilizowania czasów rozpadu produktów farmaceutycznych
KR20210129649A (ko) 2019-02-22 2021-10-28 카탈렌트 유.케이. 스윈던 지디스 리미티드 이부프로펜을 포함하는 약학적 조성물의 응집, 에어레이션 최소화 및 코팅 보존
GB2585411B (en) 2019-02-22 2023-10-04 Catalent Uk Swindon Zydis Ltd Preserving functionally-coated API particles produced by solventless mixing processes in aqueous suspension
RU2731599C1 (ru) * 2019-07-17 2020-09-04 Общество с ограниченной ответственностью "РУСИНТЕХ" Способ получения микрокапсулированного термоактивируемого огнегасящего агента
EP4188324A1 (en) 2020-07-31 2023-06-07 Catalent U.K. Swindon Zydis Limited Pharmaceutical compositions comprising coated api

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB844772A (en) * 1956-04-19 1960-08-17 Pfizer & Co C Granular pharmaceutical compositions and process for preparing same
FR2077696B1 (fi) * 1970-02-06 1973-03-16 Synthelabo
DE2211019C3 (de) * 1972-03-08 1980-08-28 Bayer Ag, 5090 Leverkusen Geschmacksverbessernde Formulierungen oraler Penicilline
US4155741A (en) * 1974-05-01 1979-05-22 Stauffer Chemical Company Stable suspension system for microencapsulated flowable formulations, and method of preparing stable suspension of microcapsules
US4126672A (en) * 1976-02-04 1978-11-21 Hoffmann-La Roche Inc. Sustained release pharmaceutical capsules
US4189499A (en) * 1977-03-16 1980-02-19 Biochefarm S.A. Lysine 4-allyloxy-3-chlorophenylacetate and method of its preparation
IT1148784B (it) * 1980-04-09 1986-12-03 Eurand Spa Procedimento per la preparazione di microcapsule in un veicolo liquido
IT1209276B (it) * 1980-11-05 1989-07-16 Magis Farmaceutici Composizione farmaceutica per la somministrazione orale del metilestere dell'acido 13a-etil-2,3,5,6,12,13,13a,13b-ottaidro-12-idrossi1h-indolo-[3,2,1-de] pirido [3,2,1-ij] [1,5] naftiridina -12-carbossilico

Also Published As

Publication number Publication date
FI86596B (fi) 1992-06-15
ES8707103A1 (es) 1987-07-16
DK7487D0 (da) 1987-01-07
DK7487A (da) 1987-01-07
DK157730C (da) 1990-07-16
NO865162L (no) 1986-12-18
US5008117A (en) 1991-04-16
NO171949C (no) 1993-05-26
CA1274144A (en) 1990-09-18
KR870700209A (ko) 1987-05-30
NZ216062A (en) 1989-07-27
ES554777A0 (es) 1987-07-16
KR900000212B1 (ko) 1990-01-23
IT1183574B (it) 1987-10-22
ZA863399B (en) 1987-01-28
RU2059409C1 (ru) 1996-05-10
FI865336A0 (fi) 1986-12-30
AU5903186A (en) 1986-12-04
EP0222856A1 (en) 1987-05-27
IT8520617A0 (it) 1985-05-08
PT82541B (pt) 1988-03-03
JPS62502859A (ja) 1987-11-12
JP2609597B2 (ja) 1997-05-14
ATE59287T1 (de) 1991-01-15
FI86596C (fi) 1992-09-25
NO171949B (no) 1993-02-15
DK157730B (da) 1990-02-12
EP0222856B1 (en) 1990-12-27
DE3676642D1 (de) 1991-02-07
HUT44168A (en) 1988-02-29
WO1986006626A1 (en) 1986-11-20
AU589644B2 (en) 1989-10-19
PT82541A (en) 1986-06-01

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Legal Events

Date Code Title Description
TC Name/ company changed in patent

Owner name: EURAND INTERNATIONAL S.P.A.

MM Patent lapsed

Owner name: EURAND INTERNATIONAL S.P.A.