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FI841619L - Nya pyrimidonderivat. - Google Patents

Nya pyrimidonderivat. Download PDF

Info

Publication number
FI841619L
FI841619L FI841619A FI841619A FI841619L FI 841619 L FI841619 L FI 841619L FI 841619 A FI841619 A FI 841619A FI 841619 A FI841619 A FI 841619A FI 841619 L FI841619 L FI 841619L
Authority
FI
Finland
Prior art keywords
rivats
pyrimidonder
new
pyrimidonder rivats
new pyrimidonder
Prior art date
Application number
FI841619A
Other languages
English (en)
Other versions
FI841619A7 (fi
FI841619A0 (fi
Inventor
Ado Kaiser
Frank Kienzle
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI841619A0 publication Critical patent/FI841619A0/fi
Publication of FI841619L publication Critical patent/FI841619L/fi
Publication of FI841619A7 publication Critical patent/FI841619A7/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60Three or more oxygen or sulfur atoms
    • C07D239/62Barbituric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI841619A 1983-05-05 1984-04-25 Uusia pyrimidonijohdannaisia. FI841619A7 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH244283 1983-05-05
CH139284 1984-03-20

Publications (3)

Publication Number Publication Date
FI841619A0 FI841619A0 (fi) 1984-04-25
FI841619L true FI841619L (fi) 1984-11-06
FI841619A7 FI841619A7 (fi) 1984-11-06

Family

ID=25687524

Family Applications (1)

Application Number Title Priority Date Filing Date
FI841619A FI841619A7 (fi) 1983-05-05 1984-04-25 Uusia pyrimidonijohdannaisia.

Country Status (16)

Country Link
US (1) US4581172A (fi)
EP (1) EP0124893A3 (fi)
AU (1) AU2751084A (fi)
CA (1) CA1237429A (fi)
CS (1) CS243486B2 (fi)
DK (1) DK198784A (fi)
ES (1) ES532172A0 (fi)
FI (1) FI841619A7 (fi)
HU (1) HUT34025A (fi)
IL (1) IL71711A (fi)
MC (1) MC1600A1 (fi)
NO (1) NO841780L (fi)
NZ (1) NZ207981A (fi)
PH (1) PH19219A (fi)
PT (1) PT78549B (fi)
ZW (1) ZW6284A1 (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3472678D1 (de) * 1983-07-18 1988-08-18 Beecham Group Plc Benzazepine and benzoxazepine derivatives
GB9707251D0 (en) * 1997-04-10 1997-05-28 Smithkline Beecham Plc Novel method and compounds
EP1165558B1 (en) * 1999-03-31 2003-09-24 Vernalis Limited Derivatives of pyrimido[6,1-a]isoquinolin-4-one
US7169907B2 (en) * 2002-03-01 2007-01-30 Roche Diagnostics Operations, Inc. Derivatives, immunogens, and antibodies for detecting ecstasy-class drugs
EP1641766A2 (en) * 2003-07-08 2006-04-05 Smithkline Beecham Corporation Novel chemical compounds
GB201502260D0 (en) 2015-02-11 2015-04-01 Verona Pharma Plc Salt of Pyrimido[6,1-A]Isoquinolin-4-one compound
WO2017016960A1 (en) * 2015-07-24 2017-02-02 F. Hoffmann-La Roche Ag Process for the preparation of (6s)-6-alkyl-10-alkoxy-9-(substituted alkoxy)-2-oxo-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid analogues
GB201613054D0 (en) 2016-07-28 2016-09-14 Verona Pharma Plc New compound and process
PL3822272T4 (pl) * 2018-07-13 2025-07-28 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Skondensowane związki tri-cykliczne jako podwójny inhibitor pde3/pde4
ES2995084T3 (en) * 2020-01-15 2025-02-05 Chia Tai Tianqing Pharmaceutical Group Co Ltd Pharmaceutical composition of tricyclic pde3/pde4 dual inhibitor compound
DK4092022T3 (da) * 2020-01-15 2025-12-01 Chia Tai Tianqing Pharmaceutical Group Co Ltd Kristal af pde3/pde4-dualhæmmer og anvendelse deraf

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2720085A1 (de) * 1977-05-05 1978-11-16 Hoechst Ag Pyrimido(6,1-a)isochinolin-2-on- derivate
NZ185900A (en) * 1976-12-10 1981-04-24 Hoechst Ag Pyrimido (6,1-a) isoquinolin-4-ones medicaments intermediate isoquinolines
FI64370C (fi) * 1977-05-05 1983-11-10 Hoechst Ag Foerfarande foer framstaellning av terapeutiskt anvaendbara pyimido-(6,1-a)isokinolin-2-imino-4-onderivat
DE2847693A1 (de) * 1978-11-03 1980-05-22 Hoechst Ag Verfahren zur herstellung von pyrimido-(6,1-a)-isochinolin-2-onen
DE3135831A1 (de) * 1981-09-10 1983-04-28 Hoechst Ag, 6230 Frankfurt 9,10-substituierte 2-mesitylimino-3-alkyl-3,4,6,7-tetrahydro-2h-pyrimido(6,1-a)isochinolin-4-one, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
US4581172A (en) 1986-04-08
DK198784D0 (da) 1984-04-17
AU2751084A (en) 1984-11-08
DK198784A (da) 1984-11-06
HUT34025A (en) 1985-01-28
PH19219A (en) 1986-02-12
ES8505369A1 (es) 1985-06-01
CS243486B2 (en) 1986-06-12
ZW6284A1 (en) 1985-10-30
FI841619A7 (fi) 1984-11-06
IL71711A (en) 1987-08-31
PT78549A (en) 1984-06-01
ES532172A0 (es) 1985-06-01
EP0124893A2 (de) 1984-11-14
MC1600A1 (fr) 1985-05-09
FI841619A0 (fi) 1984-04-25
CS325584A2 (en) 1985-08-15
EP0124893A3 (de) 1987-11-11
NO841780L (no) 1984-11-06
IL71711A0 (en) 1984-09-30
PT78549B (en) 1986-09-15
NZ207981A (en) 1987-05-29
CA1237429A (en) 1988-05-31

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Legal Events

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Owner name: F HOFFMANN-LA ROCHE & CO