FI800662A7 - 6-beta-substituerade penicillansyror som beta-laktamasinhibitorer - Google Patents

6-beta-substituerade penicillansyror som beta-laktamasinhibitorer

Info

Publication number: FI800662A7
Authority: FI; Finland
Prior art keywords: beta; penicillansyror; lactamasinhibitorer; substituerade; som
Prior art date: 1979-03-05

Application number

FI800662A

Other languages

English (en)

Other versions

FI71739C (fi

FI71739B (fi

Inventor

Michael Stephen Kellogg

Ernest Seiichi Hamanaka

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-03-05

Filing date

1980-03-04

Publication date

1980-09-06

1980-03-04 Application filed by Pfizer filed Critical Pfizer

1980-09-06 Publication of FI800662A7 publication Critical patent/FI800662A7/fi

1986-10-31 Application granted granted Critical

1986-10-31 Publication of FI71739B publication Critical patent/FI71739B/fi

1987-02-09 Publication of FI71739C publication Critical patent/FI71739C/fi

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

FI800662A 1979-03-05 1980-03-04 Foerfarande foer framstaellning av terapeutiskt anvaendbar 6- -jodpenicillansyra och estrar av denna. FI71739C (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US1780979A	1979-03-05	1979-03-05
US1780979		1979-03-05
US9683279		1979-11-23
US06/096,832 US4397783A (en)	1979-03-05	1979-11-23	Process for converting 6,6-disubstituted penicillanic acid derivatives to the 6-β-congeners

Publications (3)

Publication Number	Publication Date
FI800662A7 true FI800662A7 (fi)	1980-09-06
FI71739B FI71739B (fi)	1986-10-31
FI71739C FI71739C (fi)	1987-02-09

Family

ID=26690341

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI800662A FI71739C (fi)	1979-03-05	1980-03-04	Foerfarande foer framstaellning av terapeutiskt anvaendbar 6- -jodpenicillansyra och estrar av denna.

Country Status (29)

Country	Link
US (1)	US4397783A (fi)
KR (1)	KR840000589B1 (fi)
AR (1)	AR225758A1 (fi)
AT (1)	AT369744B (fi)
AU (1)	AU518472B2 (fi)
CA (1)	CA1154011A (fi)
CH (1)	CH648850A5 (fi)
DD (1)	DD149366A5 (fi)
DE (1)	DE3008316C2 (fi)
DK (1)	DK157136C (fi)
ES (1)	ES489186A0 (fi)
FI (1)	FI71739C (fi)
FR (1)	FR2450837A1 (fi)
GB (1)	GB2047684B (fi)
GR (1)	GR67697B (fi)
HK (1)	HK66687A (fi)
IE (1)	IE51931B1 (fi)
IL (1)	IL59514A (fi)
IT (1)	IT1130301B (fi)
KE (1)	KE3456A (fi)
LU (1)	LU82219A1 (fi)
MY (1)	MY8500320A (fi)
NL (1)	NL8001286A (fi)
NO (1)	NO800617L (fi)
OA (1)	OA06496A (fi)
PH (2)	PH18550A (fi)
PT (1)	PT70898A (fi)
SE (1)	SE451329B (fi)
SG (1)	SG56484G (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4518530A (en) *	1979-03-05	1985-05-21	Pfizer Inc.	6-β-Substituted penicillanic acids as β-lactamase inhibitors
IE49768B1 (en) *	1979-05-21	1985-12-11	Leo Pharm Prod Ltd	6beta-halopenicillanic acid derivatives
US4511512A (en) *	1980-05-01	1985-04-16	Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Produktionsaktiensel skab)	Substantially pure dicyclohexyl ammonium 6-β-bromo-penicillanate
IE51846B1 (en) *	1980-11-17	1987-04-15	Leo Pharm Prod Ltd	Pharmaceutical preparation for veterinary use and an appliance containing it
EP0139047A1 (en) *	1983-10-18	1985-05-02	Gist-Brocades N.V.	Process for the preparation of 6,6-dibromopenicillanic acid 1,1-dioxide
GB8522156D0 (en) *	1985-09-06	1985-10-09	Leo Pharm Prod Ltd	Producing chemical compounds
US4816580A (en) *	1986-04-10	1989-03-28	Leo Pharmaceutical Products Ltd. A/S	Improved method for preparing penicillanic acid derivatives
PA8579701A1 (es) *	2002-08-23	2005-05-24	Pfizer Prod Inc	Profarmaco inhibidor de beta-lactamasa
EP1636240A1 (en) *	2003-06-05	2006-03-22	Pfizer Products Inc.	Beta-lactamase inhibitor prodrug

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5749555B2 (fi) *	1973-04-04	1982-10-22
US4093625A (en) *	1976-08-09	1978-06-06	Massachusetts Institute Of Technology	6-Sulfur analogs of penicillins and cephalosporins
US4180506A (en) *	1978-01-18	1979-12-25	Rex Pratt	6β-Bromo penicillanic acid
CA1158639A (en) *	1978-12-11	1983-12-13	Eric M. Gordon	6-bromopenicillanic acid sulfone
US4203992A (en) *	1978-12-11	1980-05-20	E. R. Squibb & Sons, Inc.	β-Bromopenicillanic acid sulfone
DE3068390D1 (en) *	1979-01-10	1984-08-09	Beecham Group Plc	Penicillin derivatives, process for their preparation and pharmaceutical compositions containing certain of these compounds
IL59081A0 (en) *	1979-01-10	1980-05-30	Schering Corp	2-penem compounds and a method for preparing them

1979
- 1979-11-23 US US06/096,832 patent/US4397783A/en not_active Expired - Lifetime
1980
- 1980-03-03 GB GB8007142A patent/GB2047684B/en not_active Expired
- 1980-03-03 PH PH23716A patent/PH18550A/en unknown
- 1980-03-03 LU LU82219A patent/LU82219A1/fr unknown
- 1980-03-03 GR GR61335A patent/GR67697B/el unknown
- 1980-03-03 IL IL59514A patent/IL59514A/xx not_active IP Right Cessation
- 1980-03-04 ES ES489186A patent/ES489186A0/es active Granted
- 1980-03-04 NL NL8001286A patent/NL8001286A/nl not_active Application Discontinuation
- 1980-03-04 NO NO800617A patent/NO800617L/no unknown
- 1980-03-04 FR FR8004765A patent/FR2450837A1/fr active Granted
- 1980-03-04 AR AR225758A patent/AR225758A1/es active
- 1980-03-04 IE IE428/80A patent/IE51931B1/en not_active IP Right Cessation
- 1980-03-04 KR KR1019800000921A patent/KR840000589B1/ko not_active Expired
- 1980-03-04 CA CA000346906A patent/CA1154011A/en not_active Expired
- 1980-03-04 DE DE3008316A patent/DE3008316C2/de not_active Expired
- 1980-03-04 AU AU56105/80A patent/AU518472B2/en not_active Ceased
- 1980-03-04 DK DK092880A patent/DK157136C/da not_active IP Right Cessation
- 1980-03-04 FI FI800662A patent/FI71739C/fi not_active IP Right Cessation
- 1980-03-04 CH CH1715/80A patent/CH648850A5/de not_active IP Right Cessation
- 1980-03-04 DD DD80219434A patent/DD149366A5/de unknown
- 1980-03-04 AT AT0118980A patent/AT369744B/de not_active IP Right Cessation
- 1980-03-04 SE SE8001689A patent/SE451329B/sv not_active IP Right Cessation
- 1980-03-04 PT PT70898A patent/PT70898A/pt unknown
- 1980-03-05 IT IT20368/80A patent/IT1130301B/it active
- 1980-03-27 OA OA57065A patent/OA06496A/xx unknown
- 1980-09-12 PH PH24569A patent/PH17879A/en unknown
1984
- 1984-08-13 SG SG564/84A patent/SG56484G/en unknown
- 1984-09-24 KE KE3456A patent/KE3456A/xx unknown
1985
- 1985-12-30 MY MY320/85A patent/MY8500320A/xx unknown
1987
- 1987-09-17 HK HK666/87A patent/HK66687A/xx unknown

Also Published As

Publication number	Publication date
IT1130301B (it)	1986-06-11
SE451329B (sv)	1987-09-28
SE8001689L (sv)	1980-09-06
CA1154011A (en)	1983-09-20
ES8103095A1 (es)	1981-02-16
KE3456A (en)	1984-10-12
LU82219A1 (fr)	1980-09-24
US4397783A (en)	1983-08-09
AR225758A1 (es)	1982-04-30
ATA118980A (de)	1982-06-15
IE800428L (en)	1980-09-05
GB2047684B (en)	1983-09-28
FI71739C (fi)	1987-02-09
MY8500320A (en)	1985-12-31
CH648850A5 (de)	1985-04-15
AU5610580A (en)	1980-09-18
DK92880A (da)	1980-09-06
KR840000589B1 (ko)	1984-04-24
IE51931B1 (en)	1987-04-29
IT8020368A0 (it)	1980-03-05
DE3008316A1 (de)	1980-09-25
DE3008316C2 (de)	1982-12-16
PH18550A (en)	1985-08-09
GR67697B (fi)	1981-09-07
DK157136B (da)	1989-11-13
NO800617L (no)	1980-09-08
SG56484G (en)	1985-03-08
AT369744B (de)	1983-01-25
NL8001286A (nl)	1980-09-09
KR830001941A (ko)	1983-05-19
FR2450837B1 (fi)	1984-01-13
IL59514A (en)	1984-01-31
ES489186A0 (es)	1981-02-16
FR2450837A1 (fr)	1980-10-03
AU518472B2 (en)	1981-10-01
PH17879A (en)	1985-01-14
DK157136C (da)	1990-04-16
GB2047684A (en)	1980-12-03
IL59514A0 (en)	1980-06-30
PT70898A (en)	1980-04-01
OA06496A (fr)	1981-07-31
DD149366A5 (de)	1981-07-08
FI71739B (fi)	1986-10-31
HK66687A (en)	1987-09-25

Publication	Publication Date	Title
FI802670A7 (fi)	1981-02-28	Vattenhaltiga smoerjmedel som innehaoller ditiofosfater
FI793799A7 (fi)	1980-06-12	Aminosyraderivat anvaenda som blodtryckslaekemedel
FI790508A7 (fi)	1979-08-24	Linanordning som foerenar aotminstone tvao personer
FI812376L (fi)	1981-07-29	Mikro-organismmyceler i pelletform
FI801437A7 (fi)	1980-11-09	Anordning foer bortsortering av enstaka foeremaol som avviker fraon huvudmaengden i en loepande utmatning
FI803316L (fi)	1981-04-25	Munstycke foer massainmatning i en pappersmaskin
FI793201A7 (fi)	1981-04-16	Pappers kalanderingsfoerfarande foer papper och kalander som tillaempar foerfarandet
FI802906A7 (fi)	1981-03-23	Tillsatsaemnen i badolja
FI803253L (fi)	1981-04-17	Bensodiazepinfoereningar och deras anvaendning som laekemedel
BR8008954A (pt)	1981-10-20	Novos mercaptoorganossiloxanos
FI793943A7 (fi)	1980-10-10	Laosorgan foer en i hoernen tillslutbar papplaoda
FI800191A7 (fi)	1980-07-25	Detektor som reagerar foer vaetskestroemningar
FI800939A7 (fi)	1980-09-27	Skyddsstroemstaellare foer laeckstroem som reagerar aeven foer likstroem
FI64195B (fi)	1983-06-30	Som textiluppmjukningsaemne anvaendbar komposition
FI803028A7 (fi)	1981-03-27	Acetoxymetyl-penam-foereningar som beta-laktamasinhibitorer
FI800193A7 (fi)	1980-07-31	Ferroresonansenergikaella foer en avboejnings- och hoegspaenningskrets i en televisionsmottagare innefattande en kaella foer vaexelspaenning
FI801198A7 (fi)	1980-10-17	Oxitetracyklinsammansaettningar
FI794094A7 (fi)	1980-07-03	Inbyggnadsanordning foer en kaenselorgandosa i en genomgaongsoeppning i en elektrisk kokplatta
FI800662A7 (fi)	1980-09-06	6-beta-substituerade penicillansyror som beta-laktamasinhibitorer
FI784006A7 (fi)	1979-07-04	En braennare som formar laogan
FI801967A7 (fi)	1980-12-29	Synkron kopplad vertikalavlaenkning som styrs saovael under avsoeknings- som under aotergaongstiden
FI800876A7 (fi)	1980-10-03	X-roerelsedrift av tandroentgenapparat som ger panoramabild
FI792550A7 (fi)	1980-02-24	Signaldetektor som innehaoller en provtagnings- och haollningskrets med reducerat avlaenkningsfel
FI800673A7 (fi)	1980-09-13	Kommuterad omkopplingsregulator foer transistorerad avlaenkning som aer isolerad fraon naetet
FI802643A7 (fi)	1981-05-31	Schaktsidan i brevinmatnings- och tillslutningsmaskin

Legal Events

Date	Code	Title	Description
1996-10-14	MM	Patent lapsed
2004-08-31	MM	Patent lapsed	Owner name: PFIZER INC.