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FI3256218T3 - A kdm1a inhibitor and its use in therapy - Google Patents

A kdm1a inhibitor and its use in therapy Download PDF

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Publication number
FI3256218T3
FI3256218T3 FIEP16749986.2T FI16749986T FI3256218T3 FI 3256218 T3 FI3256218 T3 FI 3256218T3 FI 16749986 T FI16749986 T FI 16749986T FI 3256218 T3 FI3256218 T3 FI 3256218T3
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FI
Finland
Prior art keywords
therapy
polymorph
salt
compound
solvate
Prior art date
Application number
FIEP16749986.2T
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Finnish (fi)
Inventor
Hugh Young Rienhoff Jr
John M Mccall
Michael Clare
Cassandra Celatka
Amy E Tapper
Original Assignee
Imago Biosciences Inc
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Publication of FI3256218T3 publication Critical patent/FI3256218T3/en

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    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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Claims (5)

PATENTTIVAATIMUKSETPATENT CLAIMS 1. Yhdiste, jolla on kaava: O NY m NJ HN 0 <a C ; N 3 tai sen suola, polymorfi tai solvaatti.1. A compound having the formula: O NY m NJ HN 0 <a C ; N 3 or a salt, polymorph or solvate thereof. 2. Patenttivaatimuksen 1 mukainen yh- diste, suola, polymorfi tai solvaatti käytettäväksi lääkkeenä.A compound, salt, polymorph or solvate according to claim 1 for use as a medicament. 3. Farmaseuttinen koostumus, joka käsittää patenttivaatimuksen 1 mukaisen yhdisteen, suolan, polymorfin tai solvaatin yhdessä farmaseut- tisesti hyväksyttävän kantaja-aineen kanssa.A pharmaceutical composition comprising a compound, salt, polymorph or solvate according to claim 1 in association with a pharmaceutically acceptable carrier. 4. Yhdistelmä, joka käsittää patent- tivaatimuksen 1 mukaisen yhdisteen, suolan, polymorfin tai solvaatin ja toisen terapeuttisen aineen.A combination comprising a compound, salt, polymorph or solvate of claim 1 and another therapeutic agent. 5. Patenttivaatimuksen 4 mukainen vyh- distelmä käytettäväksi terapiassa.A combination according to claim 4 for use in therapy.
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HRP20250119T1 (en) 2025-03-28
MX2017010291A (en) 2017-12-07
RS66458B1 (en) 2025-02-28
JP6727216B2 (en) 2020-07-22
KR20170115095A (en) 2017-10-16
US10519118B2 (en) 2019-12-31
AU2016219041A1 (en) 2017-08-03
IL253945A0 (en) 2017-10-31
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US11230534B2 (en) 2022-01-25
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EP4559902A3 (en) 2025-08-20
PT3256218T (en) 2025-01-29

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