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FI20145751A - Menetelmä ja järjestelmä aineen liukenemisominaisuuksien määrittämiseksi - Google Patents

Menetelmä ja järjestelmä aineen liukenemisominaisuuksien määrittämiseksi

Info

Publication number
FI20145751A
FI20145751A FI20145751A FI20145751A FI20145751A FI 20145751 A FI20145751 A FI 20145751A FI 20145751 A FI20145751 A FI 20145751A FI 20145751 A FI20145751 A FI 20145751A FI 20145751 A FI20145751 A FI 20145751A
Authority
FI
Finland
Prior art keywords
substance
determining
dissolution properties
dissolution
properties
Prior art date
Application number
FI20145751A
Other languages
English (en)
Swedish (sv)
Other versions
FI127992B (fi
FI20145751A7 (fi
Inventor
Sami Svanbäck
Original Assignee
Sami Svanbäck
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sami Svanbäck filed Critical Sami Svanbäck
Priority to FI20145751A priority Critical patent/FI127992B/fi
Priority to US15/506,766 priority patent/US10520411B2/en
Priority to PCT/FI2015/050562 priority patent/WO2016030583A1/en
Publication of FI20145751A publication Critical patent/FI20145751A/fi
Publication of FI20145751A7 publication Critical patent/FI20145751A7/fi
Application granted granted Critical
Publication of FI127992B publication Critical patent/FI127992B/fi

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • G01N13/02Investigating surface tension of liquids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F21/00Dissolving
    • B01F21/20Dissolving using flow mixing
    • B01F21/22Dissolving using flow mixing using additional holders in conduits, containers or pools for keeping the solid material in place, e.g. supports or receptacles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/10Mixing by creating a vortex flow, e.g. by tangential introduction of flow components
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/10Mixing by creating a vortex flow, e.g. by tangential introduction of flow components
    • B01F25/101Mixing by creating a vortex flow, e.g. by tangential introduction of flow components wherein the vortex flows in a spherical shaped receptacle or chamber
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02Investigating particle size or size distribution
    • G01N15/0205Investigating particle size or size distribution by optical means
    • G01N15/0227Investigating particle size or size distribution by optical means using imaging; using holography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/08Regulating or influencing the flow resistance
    • B01L2400/084Passive control of flow resistance
    • B01L2400/086Passive control of flow resistance using baffles or other fixed flow obstructions
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • G01N2013/006Dissolution of tablets or the like

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Clinical Laboratory Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
FI20145751A 2014-08-29 2014-08-29 Menetelmä ja järjestelmä aineen liukenemisominaisuuksien määrittämiseksi FI127992B (fi)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FI20145751A FI127992B (fi) 2014-08-29 2014-08-29 Menetelmä ja järjestelmä aineen liukenemisominaisuuksien määrittämiseksi
US15/506,766 US10520411B2 (en) 2014-08-29 2015-08-31 Method and system for determining dissolution properties of matter
PCT/FI2015/050562 WO2016030583A1 (en) 2014-08-29 2015-08-31 Method and system for determining dissolution properties of matter

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20145751A FI127992B (fi) 2014-08-29 2014-08-29 Menetelmä ja järjestelmä aineen liukenemisominaisuuksien määrittämiseksi

Publications (3)

Publication Number Publication Date
FI20145751A true FI20145751A (fi) 2016-03-01
FI20145751A7 FI20145751A7 (fi) 2016-03-01
FI127992B FI127992B (fi) 2019-07-15

Family

ID=55398795

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20145751A FI127992B (fi) 2014-08-29 2014-08-29 Menetelmä ja järjestelmä aineen liukenemisominaisuuksien määrittämiseksi

Country Status (3)

Country Link
US (1) US10520411B2 (fi)
FI (1) FI127992B (fi)
WO (1) WO2016030583A1 (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2550539A (en) * 2016-03-21 2017-11-29 Res Center Pharmaceutical Engineering Gmbh Monitoring dissolution of a dosage form in progress during dissolution by low coherence interferometry
WO2017187023A1 (en) * 2016-04-29 2017-11-02 University Of Helsinki Method and device for physicochemical characterization of materials
EP3532985B1 (en) 2016-10-28 2023-07-12 Beckman Coulter, Inc. Substance preparation evaluation system
ES2822915T3 (es) * 2017-12-11 2021-05-05 Uponor Oyj Detección de objetos microscópicos en fluidos
GB2585076A (en) * 2019-06-28 2020-12-30 Univ Greenwich Imaging apparatus
DE102020104243A1 (de) * 2020-02-18 2021-08-19 Research Center Pharmaceutical Engineering Gmbh Interferometrie mit niedriger Kohärenz an mit thermischen Herstellungsverfahren hergestellten Zusammensetzungen
CN113610077A (zh) * 2021-07-26 2021-11-05 王昊昱 一种利用人工智能图像识别技术对溶出行为进行监控分析的系统方法及设备
CN117783459B (zh) * 2024-02-28 2024-05-07 沈阳科惠生物医药科技有限公司 一种药物的溶出曲线测定方法及系统

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997046860A2 (en) 1996-06-04 1997-12-11 Euro-Celtique, S.A. Improvements in detection systems and methods for predicting the dissolution curve of a drug from a pharmaceutical dosage form
US6497157B1 (en) * 1999-11-29 2002-12-24 Distek, Inc. Intrinsic dissolution apparatus with stationary sample holder
NL1015085C2 (nl) * 2000-05-02 2001-11-05 Stork Brabant Bv Oplosinrichting en werkwijze voor het oplossen van een deeltjesvormige vaste stof in een superkritisch of nabij kritisch flu´dum, alsmede verfinrichting.
DE60212421T2 (de) * 2001-10-11 2006-12-28 Elan Pharma International Ltd. Vorrichtung und verfahren zur gleichzeitigen beobachtung der auflösung und des äusseren erscheinungsbildes von arzneimitteln in fester darreichungsform
US7846382B2 (en) 2002-06-04 2010-12-07 Protasis Corporation Method and device for ultrasonically manipulating particles within a fluid
WO2010006166A2 (en) 2008-07-09 2010-01-14 Advanced Liquid Logic, Inc. Bead manipulation techniques
CN101548172A (zh) 2006-12-01 2009-09-30 皇家飞利浦电子股份有限公司 流式细胞操纵器
US20100262381A1 (en) 2007-06-29 2010-10-14 Zeng William B Method of manufacturing and testing solid dosage products and apparatus for the testing
US20100209927A1 (en) * 2007-11-06 2010-08-19 Menon Vinod P Processing device tablet
US8119998B2 (en) 2008-01-04 2012-02-21 Pion, Inc. Methods and systems for in situ physicochemical property testing
US20090207691A1 (en) 2008-02-14 2009-08-20 Varian, Inc. Dissolution test vessel with rotational agitation
US8631685B2 (en) 2008-10-15 2014-01-21 Massachusetts Institute Of Technology Method and apparatus for extended time and varying environment measurements of single particles in microfluidic channels
US9133499B2 (en) * 2010-09-14 2015-09-15 The Regents Of The University Of California Method and device for isolating cells from heterogeneous solution using microfluidic trapping vortices
EP2458367B1 (de) 2010-11-25 2015-08-05 Mettler-Toledo AG Vorrichtung und Verfahren zur Erkennung fester Substanzen in einer flüssigen Phase
TWI648532B (zh) * 2011-08-29 2019-01-21 美商安美基公司 用於非破壞性檢測-流體中未溶解粒子之方法及裝置
US9304065B2 (en) 2012-02-29 2016-04-05 Fluidigm Corporation Methods, systems and devices for multiple single-cell capturing and processing using microfluidics
WO2013177560A1 (en) 2012-05-25 2013-11-28 The Regents Of The University Of California Microfluidic systems for particle trapping and separation
JP6025982B2 (ja) 2012-08-01 2016-11-16 ザ・ペン・ステート・リサーチ・ファンデーション 粒子および細胞の高効率分離およびマニピュレーション
EP2749866B1 (en) 2012-12-31 2016-03-16 Universiteit Gent Molecular analysis device

Also Published As

Publication number Publication date
US20180231446A1 (en) 2018-08-16
FI127992B (fi) 2019-07-15
US10520411B2 (en) 2019-12-31
WO2016030583A1 (en) 2016-03-03
FI20145751A7 (fi) 2016-03-01

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