[go: up one dir, main page]

FI20020053L - Watson-Crick -DNA:n muuntaminen Hoogsteen-pariutuneeksi kaksoiskierteeksi - Google Patents

Watson-Crick -DNA:n muuntaminen Hoogsteen-pariutuneeksi kaksoiskierteeksi Download PDF

Info

Publication number
FI20020053L
FI20020053L FI20020053A FI20020053A FI20020053L FI 20020053 L FI20020053 L FI 20020053L FI 20020053 A FI20020053 A FI 20020053A FI 20020053 A FI20020053 A FI 20020053A FI 20020053 L FI20020053 L FI 20020053L
Authority
FI
Finland
Prior art keywords
hoogsteen
watson
double helix
paired double
dna conversion
Prior art date
Application number
FI20020053A
Other languages
English (en)
Swedish (sv)
Other versions
FI20020053A7 (fi
Inventor
Donald M Gray
Gihan M Hasheim
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas filed Critical Univ Texas
Publication of FI20020053A7 publication Critical patent/FI20020053A7/fi
Publication of FI20020053L publication Critical patent/FI20020053L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6839Triple helix formation or other higher order conformations in hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/15Nucleic acids forming more than 2 strands, e.g. TFOs
    • C12N2310/152Nucleic acids forming more than 2 strands, e.g. TFOs on a single-stranded target, e.g. fold-back TFOs
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/31Chemical structure of the backbone
    • C12N2310/317Chemical structure of the backbone with an inverted bond, e.g. a cap structure

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
FI20020053A 1999-07-20 2002-01-11 Watson-Crick -DNA:n muuntaminen Hoogsteen-pariutuneeksi kaksoiskierteeksi FI20020053L (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35742499A 1999-07-20 1999-07-20
US09/487,130 US6362322B1 (en) 1999-07-20 2000-01-19 Conversion of a watson-crick DNA to a hoogsteen-paired duplex
PCT/US2000/019783 WO2001005937A2 (en) 1999-07-20 2000-07-20 Conversion of a watson-crick dna to a hoogsteen-paired duplex

Publications (2)

Publication Number Publication Date
FI20020053A7 FI20020053A7 (fi) 2002-03-13
FI20020053L true FI20020053L (fi) 2002-03-13

Family

ID=26999647

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20020053A FI20020053L (fi) 1999-07-20 2002-01-11 Watson-Crick -DNA:n muuntaminen Hoogsteen-pariutuneeksi kaksoiskierteeksi

Country Status (10)

Country Link
US (1) US6362322B1 (fi)
JP (1) JP2003507079A (fi)
AU (1) AU777923B2 (fi)
CA (1) CA2376518A1 (fi)
DE (1) DE10084821T1 (fi)
DK (1) DK200200087A (fi)
FI (1) FI20020053L (fi)
GB (1) GB2368340A (fi)
SE (1) SE0200136L (fi)
WO (1) WO2001005937A2 (fi)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5473060A (en) * 1993-07-02 1995-12-05 Lynx Therapeutics, Inc. Oligonucleotide clamps having diagnostic applications

Also Published As

Publication number Publication date
GB0203791D0 (en) 2002-04-03
DK200200087A (da) 2002-01-18
JP2003507079A (ja) 2003-02-25
GB2368340A (en) 2002-05-01
FI20020053A7 (fi) 2002-03-13
SE0200136L (sv) 2002-03-14
AU6491500A (en) 2001-02-05
WO2001005937A3 (en) 2001-11-01
SE0200136D0 (sv) 2002-01-18
WO2001005937A2 (en) 2001-01-25
CA2376518A1 (en) 2001-01-25
US6362322B1 (en) 2002-03-26
DE10084821T1 (de) 2003-12-04
AU777923B2 (en) 2004-11-04

Similar Documents

Publication Publication Date Title
DE50107556D1 (de) Graphem-Phonem-Konvertierung
IL153896A0 (en) Toothbrush with longitudinal to lateral motion conversion
NL300427I2 (en) Antibodoes to human IL-1 beta
DK1248675T3 (da) Katalytisk reaktor
GB9930691D0 (en) Improvements relating to double-stranded RNA inhibition
IL155822A0 (en) Improved efficiency water dasalination/purification
EP1395317A4 (en) IMPROVEMENTS OF A SYRINGE FOR SINGLE USE
GB0006513D0 (en) Improvements relating to converters
ID26441A (id) Proses untuk memproduksi ftalat anhidrida
AU2001278987A1 (en) A systematic approach to mechanism-of-response analyses
ITGE990089A0 (it) Motore a basso consumo energetico.
DE60017937D1 (de) Digital zu analog-wandler
GB2364338B (en) Improvements relating to construction
FI20020053L (fi) Watson-Crick -DNA:n muuntaminen Hoogsteen-pariutuneeksi kaksoiskierteeksi
DE60014568D1 (de) Analog-digital-wandlung
NO20023164L (no) Buekonstruksjon
FI990641A0 (fi) Menetelmä kaupankäynnin tehostamiseen
DE69929757D1 (de) Farbumwandlung
IT1318243B1 (it) Sistema per vincolare dispositivi elastomerici ad una strutturaportante,
EP1193691A4 (en) CONVERTER AUFHAENGUNGSSTRUKTUR
BR1101067A (pt) Construção de dna para melhorar a eficiência de transcrição
GB0013199D0 (en) Improvements to matrix converters
GB9916268D0 (en) Improvements to flue arrangements
SE9901088D0 (sv) Bränslekonvertering
AU2002223779A1 (en) Use of a nucleic acid to provide a plant with resistance to attack by a pathogen