ES8802014A1 - Un procedimiento para la preparacion de derivados de ariletanolamina. - Google Patents
Un procedimiento para la preparacion de derivados de ariletanolamina.Info
- Publication number
- ES8802014A1 ES8802014A1 ES553415A ES553415A ES8802014A1 ES 8802014 A1 ES8802014 A1 ES 8802014A1 ES 553415 A ES553415 A ES 553415A ES 553415 A ES553415 A ES 553415A ES 8802014 A1 ES8802014 A1 ES 8802014A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- formula
- hydrogen
- chem
- bond
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000002058 anti-hyperglycaemic effect Effects 0.000 title 1
- 230000003579 anti-obesity Effects 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/111—Aromatic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Polymers & Plastics (AREA)
- Endocrinology (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Emergency Medicine (AREA)
- Food Science & Technology (AREA)
- Child & Adolescent Psychology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Fodder In General (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE ARILETANOLAMINA, DE FORMULA GENERAL (I), Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. COMPRENDE LAS OPERACIONES DE REDUCIR UN RESTO DE FORMULA GENERAL (II) CON EL COMPUESTO DE FORMULA GENERAL (III), CON HIDROGENO PROCEDENTE DE UN HIDRURO METALICO COMPLEJO, EN UN DISOLVENTE APROPIADO TAL COMO UN DISOLVENTE APROTICO SELECCIONADO ENTRE ETER DIETILICO, DIOXANO, BENCENO O TOLUENO, Y A UNA TEMPERATURA COMPRENDIDA ENTRE 0 GRADOS Y LA TEMPERATURA DE REFLUJO DEL DISOLVENTE; DE PROTEGER CUALQUIER RESTO -NHEN EL COMPUESTO DE FORMULA GENERAL (III) UTILIZANDO PARA ELLO CUALQUIER GRUPO PROTECTOR DE NITROGENO; Y DE SEPARAR CUALQUIER PRODUCTO REQUERIDO. DE APLICACION EN MEDICINA Y AGRICULTURA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858507942A GB8507942D0 (en) | 1985-03-27 | 1985-03-27 | Compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES553415A0 ES553415A0 (es) | 1988-03-16 |
| ES8802014A1 true ES8802014A1 (es) | 1988-03-16 |
Family
ID=10576719
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES553415A Expired ES8802014A1 (es) | 1985-03-27 | 1986-03-25 | Un procedimiento para la preparacion de derivados de ariletanolamina. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0196849A3 (es) |
| JP (1) | JPS61251645A (es) |
| AU (1) | AU5509986A (es) |
| DK (1) | DK145386A (es) |
| ES (1) | ES8802014A1 (es) |
| GB (1) | GB8507942D0 (es) |
| GR (1) | GR860797B (es) |
| PT (1) | PT82294B (es) |
| ZA (1) | ZA862234B (es) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0233686A3 (en) * | 1986-01-11 | 1989-05-03 | Beecham Group Plc | Bis phenyl ethanol amines and bis phenyoxypropanolamines having a beta-agonist activity |
| US5563171A (en) * | 1993-11-05 | 1996-10-08 | American Cyanamid Company | Treatment of glaucoma and ocular hypertension with β3-adrenergic agonists |
| US5578638A (en) * | 1993-11-05 | 1996-11-26 | American Cyanamid Company | Treatment of glaucoma and ocular hypertension with β3 -adrenergic agonists |
| ZA967892B (en) * | 1995-09-21 | 1998-03-18 | Lilly Co Eli | Selective β3 adrenergic agonists. |
| US6075040A (en) * | 1996-09-05 | 2000-06-13 | Eli Lilly And Company | Selective β3 adrenergic agonists |
| ES2171839T3 (es) * | 1996-09-05 | 2002-09-16 | Lilly Co Eli | Analogos de carbazol como agonistas adrenergicos selectivos de beta3. |
| CO5011072A1 (es) * | 1997-12-05 | 2001-02-28 | Lilly Co Eli | Etanolaminas pirazinil substituidas como agfonistas de los receptores |
| US6541669B1 (en) | 1998-06-08 | 2003-04-01 | Theravance, Inc. | β2-adrenergic receptor agonists |
| US6713651B1 (en) | 1999-06-07 | 2004-03-30 | Theravance, Inc. | β2-adrenergic receptor agonists |
| US6683115B2 (en) | 1999-06-02 | 2004-01-27 | Theravance, Inc. | β2-adrenergic receptor agonists |
| US6593497B1 (en) | 1999-06-02 | 2003-07-15 | Theravance, Inc. | β2-adrenergic receptor agonists |
| UA73965C2 (en) | 1999-12-08 | 2005-10-17 | Theravance Inc | b2 ADRENERGIC RECEPTOR ANTAGONISTS |
| US6653323B2 (en) | 2001-11-13 | 2003-11-25 | Theravance, Inc. | Aryl aniline β2 adrenergic receptor agonists |
| TWI249515B (en) | 2001-11-13 | 2006-02-21 | Theravance Inc | Aryl aniline beta2 adrenergic receptor agonists |
| JP2005527618A (ja) | 2002-05-28 | 2005-09-15 | セラヴァンス インコーポレーテッド | アルコキシアリールβ２アドレナリン作動性レセプターアゴニスト |
| TW200526547A (en) | 2003-09-22 | 2005-08-16 | Theravance Inc | Amino-substituted ethylamino β2 adrenergic receptor agonists |
| TW200531692A (en) | 2004-01-12 | 2005-10-01 | Theravance Inc | Aryl aniline derivatives as β2 adrenergic receptor agonists |
| RU2006146042A (ru) | 2004-06-03 | 2008-07-20 | Тереванс | Диаминные агонисты 2-адренергических рецепторов |
| EP1786762A2 (en) | 2004-09-10 | 2007-05-23 | Theravance, Inc. | Amidine substituted aryl aniline compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE786713A (fr) * | 1971-07-27 | 1973-01-25 | Sandoz Sa | Nouveaux amino-alcools, leur preparation et leur application comme medicaments |
| DE2303304A1 (de) * | 1973-01-24 | 1973-08-02 | Sandoz Ag | Verfahren zur herstellung neuer carbocyclischer verbindungen |
| IL60530A (en) * | 1979-08-16 | 1984-10-31 | American Cyanamid Co | Animal feed compositions useful as growth promotors and for reduction of fat in animals,comprising phenylethanolamine derivatives and certain such novel compounds |
-
1985
- 1985-03-27 GB GB858507942A patent/GB8507942D0/en active Pending
-
1986
- 1986-03-24 EP EP86302145A patent/EP0196849A3/en not_active Ceased
- 1986-03-25 ES ES553415A patent/ES8802014A1/es not_active Expired
- 1986-03-25 AU AU55099/86A patent/AU5509986A/en not_active Abandoned
- 1986-03-25 ZA ZA862234A patent/ZA862234B/xx unknown
- 1986-03-26 GR GR860797A patent/GR860797B/el unknown
- 1986-03-26 JP JP61068280A patent/JPS61251645A/ja active Pending
- 1986-03-26 DK DK145386A patent/DK145386A/da not_active IP Right Cessation
- 1986-03-27 PT PT82294A patent/PT82294B/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU5509986A (en) | 1986-10-02 |
| EP0196849A2 (en) | 1986-10-08 |
| PT82294A (en) | 1986-04-01 |
| DK145386D0 (da) | 1986-03-26 |
| JPS61251645A (ja) | 1986-11-08 |
| PT82294B (en) | 1988-01-11 |
| GR860797B (en) | 1986-07-21 |
| DK145386A (da) | 1986-09-28 |
| EP0196849A3 (en) | 1988-01-07 |
| ES553415A0 (es) | 1988-03-16 |
| GB8507942D0 (en) | 1985-05-01 |
| ZA862234B (en) | 1986-12-30 |
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