ES8800658A1 - Procedimiento para la sintesis de derivados de acidos omega-aminados - Google Patents
Procedimiento para la sintesis de derivados de acidos omega-aminadosInfo
- Publication number
- ES8800658A1 ES8800658A1 ES546625A ES546625A ES8800658A1 ES 8800658 A1 ES8800658 A1 ES 8800658A1 ES 546625 A ES546625 A ES 546625A ES 546625 A ES546625 A ES 546625A ES 8800658 A1 ES8800658 A1 ES 8800658A1
- Authority
- ES
- Spain
- Prior art keywords
- branched
- linear
- substituted
- radicals
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 208000012661 Dyskinesia Diseases 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 208000005392 Spasm Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 230000000507 anthelmentic effect Effects 0.000 abstract 1
- 239000000921 anthelmintic agent Substances 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000007547 defect Effects 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000036543 hypotension Effects 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE ACIDOS OMEGA-AMINADOS, DE FORMULA (I), Y DE SUS ISOMEROS OPTICOS, MEZCLAS RACEMICAS Y SALES. COMPRENDE LA REACCION DE UNA AMINA DE FORMULA RNHR1 CON UN COMPUESTO DE FORMULA (II), PARA OBTENER UN COMPUESTO DE FORMULA (I), EN LAS QUE W REPRESENTA CLORO, BROMO O YODO, R Y R1 PUEDEN SER VARIOS TIPOS DE RADICALES, R2 ES GRUPO AMINICO Y N VALE 3-5. LA REACCION SE EFECTUA EN UN DISOLVENTE ORGANICO INERTE, EN PRESENCIA DE UNA BASE, A UNA TEMPERATURA COMPRENDIDA ENTRE 0JC Y LA DE REFLUJO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE AFECCIONES NEUROLOGICAS, PSIQUICAS O CARDIOVASCULARES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU84343 | 1982-08-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES546625A0 ES546625A0 (es) | 1987-11-16 |
| ES8800658A1 true ES8800658A1 (es) | 1987-11-16 |
Family
ID=19729937
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES525031A Granted ES525031A0 (es) | 1982-08-20 | 1983-08-19 | Procedimiento para la preparacion de acidos omega anillados |
| ES546625A Expired ES8800658A1 (es) | 1982-08-20 | 1985-09-02 | Procedimiento para la sintesis de derivados de acidos omega-aminados |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES525031A Granted ES525031A0 (es) | 1982-08-20 | 1983-08-19 | Procedimiento para la preparacion de acidos omega anillados |
Country Status (24)
| Country | Link |
|---|---|
| JP (1) | JPS5962555A (es) |
| KR (1) | KR870000980B1 (es) |
| AU (2) | AU1814083A (es) |
| BE (1) | BE897566A (es) |
| CA (1) | CA1256899A (es) |
| CH (1) | CH659466A5 (es) |
| DE (2) | DE3347867C2 (es) |
| DK (1) | DK373383A (es) |
| ES (2) | ES525031A0 (es) |
| FI (1) | FI832935A7 (es) |
| FR (1) | FR2531950B1 (es) |
| GB (1) | GB2126224B (es) |
| GR (1) | GR77444B (es) |
| IE (1) | IE55872B1 (es) |
| IL (1) | IL69543A (es) |
| IT (1) | IT1169767B (es) |
| MA (1) | MA19882A1 (es) |
| MX (1) | MX156348A (es) |
| NL (1) | NL8302916A (es) |
| NO (1) | NO163770C (es) |
| OA (1) | OA07525A (es) |
| PT (1) | PT77226B (es) |
| SE (1) | SE8304513L (es) |
| ZA (1) | ZA836130B (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0133795B1 (en) * | 1983-08-01 | 1989-01-18 | THE McLEAN HOSPITAL CORPORATION | Gaba esters and gaba analogue esters |
| DE3445816C1 (de) | 1984-12-15 | 1986-06-12 | Behringwerke Ag, 3550 Marburg | Flaechenfoermiges diagnostisches Mittel |
| GB8813185D0 (en) * | 1988-06-03 | 1988-07-06 | Wyeth John & Brother Ltd | New method & amines used therein |
| CA2028782C (en) * | 1989-11-07 | 2003-10-14 | Christian T. Goralski | Process for the production of vinyl-gaba |
| US5585358A (en) * | 1993-07-06 | 1996-12-17 | Yissum Research Development Corporation Of The Hebrew University Of Jerusalem | Derivatives of valproic acid amides and 2-valproenoic acid amides, method of making and use thereof as anticonvulsant agents |
| ATE241351T1 (de) | 1996-07-24 | 2003-06-15 | Warner Lambert Co | Isobutylgaba und dessen derivate zur schmerzbehandlung |
| FR2753967B1 (fr) * | 1996-09-27 | 1998-11-27 | Sod Conseils Rech Applic | Nouveaux derives de la phenoxyethylamine, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
| UA59384C2 (uk) | 1996-12-20 | 2003-09-15 | Пфайзер, Інк. | Похідні сульфонамідів та амідів як агоністи простагландину, фармацевтична композиція та способи лікування на їх основі |
| UA67754C2 (uk) | 1997-10-10 | 2004-07-15 | Пфайзер, Інк. | Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти) |
| CN1251758C (zh) | 2000-07-21 | 2006-04-19 | 特瓦制药工业有限公司 | 丙戊酸和2-丙基戊烯酸酰胺的衍生物在制备治疗双极情感障碍症躁狂病药物中的用途 |
| EP1339669B1 (en) | 2000-11-21 | 2008-06-04 | UCB Pharma, S.A. | N-alkylated gaba compounds, processes for their preparation and their use as medicaments |
| JP2007509072A (ja) | 2003-10-16 | 2007-04-12 | キャラ セラピューティックス, インコーポレイテッド | アミドまたはチオアミド誘導体および疼痛の処置におけるその使用方法 |
| FR3018076B1 (fr) * | 2014-03-03 | 2016-02-19 | Arkema France | Procede de preparation de derives de l'acide 11-aminoundecanoique et de l'acide 12-aminododecanoique |
| WO2020031201A1 (en) * | 2018-08-04 | 2020-02-13 | Msn Laboratories Private Limited, R&D Center | Improved process for the preparation of 6-aminohexanoic acid |
| CN109593044B (zh) * | 2018-12-06 | 2021-05-14 | 盐城工学院 | 一种烷基脂肪酸胺及其制备方法 |
| CN115636761B (zh) * | 2021-07-20 | 2024-07-05 | 中国石油天然气股份有限公司 | 一种油溶性表面活性剂、驱油剂及其应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE636245A (es) | ||||
| GB586645A (en) * | 1944-07-19 | 1947-03-26 | Burroughs Wellcome Co | Improvements relating to the synthesis of amino acid derivatives and salts thereof |
| GB775364A (en) * | 1954-05-05 | 1957-05-22 | Unilever Ltd | Improvements in soap compositions |
| US2851345A (en) * | 1955-02-02 | 1958-09-09 | Armour & Co | Fuel oil compositions |
| DE1189556B (de) * | 1962-05-29 | 1965-03-25 | Sandoz Ag | Verfahren zur Herstellung von 3-Diaethylaminobuttersaeure-N-methylanilid |
| BE647556A (es) * | 1964-05-06 | 1964-08-31 | ||
| IE33790B1 (en) * | 1968-06-04 | 1974-10-30 | Beecham Group Ltd | Derivatives of n-acylaminoacid amides |
| US3954778A (en) * | 1970-03-03 | 1976-05-04 | Zambon S.P.A. | Aminoacetyl derivatives of 2,3-diphenyl cyclopropyl amine |
| GB1369250A (en) * | 1970-08-07 | 1974-10-02 | Pfizer | Amines the preparation thereof and their use in pharmacejtical compositions |
| DE2234399A1 (de) * | 1972-07-17 | 1974-01-31 | Thomae Gmbh Dr K | Hautschutzmittel |
| US3947579A (en) | 1974-06-03 | 1976-03-30 | Nelson Research & Development Company | Method and composition for potentiating neuroleptic drugs |
| GB1538207A (en) * | 1975-12-09 | 1979-01-10 | Mitsubishi Chem Ind | N2-arylsulphonyl-l-argininamides and the pharmaceutically acceptable salts thereof |
| LU78804A1 (de) * | 1977-12-30 | 1979-07-20 | Byk Gulden Lomberg Chem Fab | N-substituierte w-aminoalkanoyl-w-aminoalkansaeuren,ihre verwendung und verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
| LU78805A1 (de) * | 1977-12-30 | 1979-07-20 | Byk Gulden Lomberg Chem Fab | Acylhydrocarbylaminoalkansaeuren,ihre herstellung und verwendung sowie sie enthaltende arzneimittel |
| DE3010599A1 (de) * | 1979-03-22 | 1980-10-09 | Continental Pharma | Derivate von glycinamid, deren herstellung und verwendung |
-
1983
- 1983-08-16 FI FI832935A patent/FI832935A7/fi not_active Application Discontinuation
- 1983-08-16 DK DK373383A patent/DK373383A/da not_active Application Discontinuation
- 1983-08-17 CA CA000434769A patent/CA1256899A/en not_active Expired
- 1983-08-17 DE DE3347867A patent/DE3347867C2/de not_active Expired
- 1983-08-17 DE DE19833329628 patent/DE3329628A1/de active Granted
- 1983-08-18 GR GR72245A patent/GR77444B/el unknown
- 1983-08-18 IE IE1933/83A patent/IE55872B1/en unknown
- 1983-08-18 GB GB08322245A patent/GB2126224B/en not_active Expired
- 1983-08-18 NO NO832965A patent/NO163770C/no unknown
- 1983-08-19 IT IT22591/83A patent/IT1169767B/it active
- 1983-08-19 AU AU18140/83A patent/AU1814083A/en not_active Abandoned
- 1983-08-19 NL NL8302916A patent/NL8302916A/nl not_active Application Discontinuation
- 1983-08-19 CH CH4544/83A patent/CH659466A5/fr not_active IP Right Cessation
- 1983-08-19 MX MX198462A patent/MX156348A/es unknown
- 1983-08-19 PT PT77226A patent/PT77226B/pt not_active IP Right Cessation
- 1983-08-19 ZA ZA836130A patent/ZA836130B/xx unknown
- 1983-08-19 OA OA58092A patent/OA07525A/xx unknown
- 1983-08-19 SE SE8304513A patent/SE8304513L/xx not_active Application Discontinuation
- 1983-08-19 BE BE0/211380A patent/BE897566A/fr not_active IP Right Cessation
- 1983-08-19 FR FR8313490A patent/FR2531950B1/fr not_active Expired
- 1983-08-19 ES ES525031A patent/ES525031A0/es active Granted
- 1983-08-20 JP JP58150964A patent/JPS5962555A/ja active Granted
- 1983-08-20 MA MA20104A patent/MA19882A1/fr unknown
- 1983-08-20 KR KR1019830003898A patent/KR870000980B1/ko not_active Expired
- 1983-08-22 IL IL69543A patent/IL69543A/xx unknown
-
1985
- 1985-09-02 ES ES546625A patent/ES8800658A1/es not_active Expired
-
1988
- 1988-04-18 AU AU14727/88A patent/AU1472788A/en not_active Abandoned
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