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ES8706664A1 - Procedimiento para preparar compuestos carbostirilicos - Google Patents

Procedimiento para preparar compuestos carbostirilicos

Info

Publication number
ES8706664A1
ES8706664A1 ES550113A ES550113A ES8706664A1 ES 8706664 A1 ES8706664 A1 ES 8706664A1 ES 550113 A ES550113 A ES 550113A ES 550113 A ES550113 A ES 550113A ES 8706664 A1 ES8706664 A1 ES 8706664A1
Authority
ES
Spain
Prior art keywords
same
processes
compositions containing
preparing
carbostyril compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES550113A
Other languages
English (en)
Other versions
ES550113A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP60272086A external-priority patent/JPH07100696B2/ja
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Publication of ES550113A0 publication Critical patent/ES550113A0/es
Publication of ES8706664A1 publication Critical patent/ES8706664A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

METODO DE PREPARAR COMPUESTOS CARBOSTIRILICOS. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (R''-W), EN PRESENCIA DE UN COMPUESTO BASICO, EN UN DISOLVENTE, A TEMPERATURA COMPRENDIDAS ENTRE -20 Y 70GC Y DURANTE UN TIEMPO ENTRE ALGUNOS MINUTOS Y 12 HORAS, PARA OBTENER COMPUESTOS CARBOSTIRILICOS DE FORMULA (I) DONDE R ELEVADO A 1 ES UN GRUPO ALCANOILO INFERIOR, ALCOXICARBONILO INFERIOR, ALCOXICARBONILO INFERIRO-ALQUILO INFERIOR, FENILO-ALQUILO Y OTROS; Y R ELEVADO A 2 ES UN GRUPO BENZOILO QUE PUEDE TENER OPCIONALMENTE SOBRE SU ANILLO FENILICO UN GRUPO ALCOXI INFERIOR. TIENEN APLICACIONES FARMACEUTICAS COMO AGENTES CARDIOTONICOS. *FORMULA*
ES550113A 1984-12-18 1985-12-18 Procedimiento para preparar compuestos carbostirilicos Expired ES8706664A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP26818984 1984-12-18
JP60272086A JPH07100696B2 (ja) 1984-12-18 1985-12-03 カルボスチリル誘導体

Publications (2)

Publication Number Publication Date
ES550113A0 ES550113A0 (es) 1987-07-16
ES8706664A1 true ES8706664A1 (es) 1987-07-16

Family

ID=26548202

Family Applications (1)

Application Number Title Priority Date Filing Date
ES550113A Expired ES8706664A1 (es) 1984-12-18 1985-12-18 Procedimiento para preparar compuestos carbostirilicos

Country Status (5)

Country Link
US (1) US4760064A (es)
EP (1) EP0187322B1 (es)
DE (1) DE3576500D1 (es)
DK (1) DK168522B1 (es)
ES (1) ES8706664A1 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5358949A (en) * 1986-03-05 1994-10-25 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives
DE3784401T2 (de) * 1986-07-31 1993-08-12 Otsuka Pharma Co Ltd Karbostyril-derivate und ihre salze, verfahren zu ihrer herstellung und diese enthaltende kardiotonische zusammensetzung.
US5166160A (en) * 1986-12-23 1992-11-24 Burroughs Wellcome Co. Quinoline compound
GB8630702D0 (en) * 1986-12-23 1987-02-04 Wellcome Found Quinoline compound
US4831031A (en) * 1988-01-22 1989-05-16 Pfizer Inc. Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity
GB8820174D0 (en) * 1988-08-25 1988-09-28 Wellcome Found Quinoline compound
US5753677A (en) * 1989-10-20 1998-05-19 Otsuka Pharmaceutical Co., Ltd. Benzoheterocyclic compounds
US5985869A (en) * 1989-10-20 1999-11-16 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
DE69026708T2 (de) * 1989-10-20 1997-04-03 Otsuka Pharma Co Ltd Benzoheterozyklische verbindungen
US5258510A (en) * 1989-10-20 1993-11-02 Otsuka Pharma Co Ltd Benzoheterocyclic compounds
DE4208304A1 (de) * 1992-03-16 1993-09-23 Merck Patent Gmbh 2-oxochinolinderivate
US5464833A (en) * 1992-08-19 1995-11-07 Otsuka Pharmaceutical Co., Ltd. Apoptosis regulating composition
US5780480A (en) * 1996-02-28 1998-07-14 Merck & Co., Inc. Fibrinogen receptor antagonists
JP2000505471A (ja) * 1996-02-28 2000-05-09 メルク エンド カンパニー インコーポレーテッド フィブリノーゲン受容体拮抗物質
PT2332909E (pt) * 2005-04-13 2014-12-17 Astex Therapeutics Ltd Derivados de hidroxibenzamida e sua utilização como inibidores de hsp90
US7754725B2 (en) * 2006-03-01 2010-07-13 Astex Therapeutics Ltd. Dihydroxyphenyl isoindolymethanones
GB0620259D0 (en) * 2006-10-12 2006-11-22 Astex Therapeutics Ltd Pharmaceutical compounds
JP5721949B2 (ja) * 2006-10-12 2015-05-20 アステックス、セラピューティックス、リミテッドＡｓｔｅｘ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｌｉｍｉｔｅｄ 複合薬剤
EP2073807A1 (en) * 2006-10-12 2009-07-01 Astex Therapeutics Limited Pharmaceutical combinations
JP5518478B2 (ja) 2006-10-12 2014-06-11 アステックス、セラピューティックス、リミテッド 医薬化合物
JP5528806B2 (ja) * 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
JP5410285B2 (ja) * 2006-10-12 2014-02-05 アステックス、セラピューティックス、リミテッド 医薬化合物
PE20090188A1 (es) * 2007-03-15 2009-03-20 Novartis Ag Compuestos heterociclicos como moduladores de la senda de hedgehog
GB0806527D0 (en) 2008-04-11 2008-05-14 Astex Therapeutics Ltd Pharmaceutical compounds
US20100041663A1 (en) 2008-07-18 2010-02-18 Novartis Ag Organic Compounds as Smo Inhibitors
GB2532990A (en) 2014-12-05 2016-06-08 Schlumberger Holdings Corrosion inhibition
GB2543498A (en) 2015-10-19 2017-04-26 Schlumberger Holdings Corrosion inhibition

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5777676A (en) * 1980-10-31 1982-05-15 Otsuka Pharmaceut Co Ltd Carbostyril derivative

Also Published As

Publication number Publication date
EP0187322B1 (en) 1990-03-14
US4760064A (en) 1988-07-26
DK586185A (da) 1986-06-19
EP0187322A1 (en) 1986-07-16
DK586185D0 (da) 1985-12-17
ES550113A0 (es) 1987-07-16
DK168522B1 (da) 1994-04-11
DE3576500D1 (de) 1990-04-19

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000201