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ES8705434A1 - Procedimiento para la preparacion de derivados de acido 4-(isoxazolil)-tiazol-2-oxamico - Google Patents

Procedimiento para la preparacion de derivados de acido 4-(isoxazolil)-tiazol-2-oxamico

Info

Publication number
ES8705434A1
ES8705434A1 ES552514A ES552514A ES8705434A1 ES 8705434 A1 ES8705434 A1 ES 8705434A1 ES 552514 A ES552514 A ES 552514A ES 552514 A ES552514 A ES 552514A ES 8705434 A1 ES8705434 A1 ES 8705434A1
Authority
ES
Spain
Prior art keywords
compound
formula
isoxazolyl
thiazole
acid derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES552514A
Other languages
English (en)
Other versions
ES552514A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon SpA
Original Assignee
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon SpA filed Critical Zambon SpA
Publication of ES8705434A1 publication Critical patent/ES8705434A1/es
Publication of ES552514A0 publication Critical patent/ES552514A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/12—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS DE FORMULA (I) Y DE SUS SALES CON BASES, FISIOLOGICAMENTE COMPATIBLES. COMPRENDE LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA W-CO-CO-Y; SEGUIDA DE LA HIDROLISIS DEL COMPUESTO ASI FORMADO POR TRATAMIENTO CON UNA DISOLUCION ACUOSA DE UNA BASE, PARA FORMAR EL COMPUESTO DE FORMULA (I), EN LAS QUE R, R1 Y W PUEDEN SER VARIOS RADICALES, R7 REPRESENTA HIDROGENO O ALQUILO C1-3 E Y ES CLORO O BROMO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LA ARTRITIS REUMATOIDE.
ES552514A 1984-07-31 1986-02-28 Procedimiento para la preparacion de derivados de acido 4-(isoxazolil)-tiazol-2-oxamico Expired ES8705434A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22150/84A IT1183061B (it) 1984-07-31 1984-07-31 Composti dotati di attivita'antiallergica

Publications (2)

Publication Number Publication Date
ES8705434A1 true ES8705434A1 (es) 1987-05-01
ES552514A0 ES552514A0 (es) 1987-05-01

Family

ID=11192238

Family Applications (4)

Application Number Title Priority Date Filing Date
ES546420A Expired ES8608516A1 (es) 1984-07-31 1985-07-30 Procedimiento para la preparacion de acidos 4-isoxazolil- tiazol-2-oxamicos y sus derivados
ES546419A Expired ES8703459A1 (es) 1984-07-31 1985-07-30 Procedimiento para la preparacion de derivados de acido 4- (isoxazolil)-tiazol-2-oxamico
ES552514A Expired ES8705434A1 (es) 1984-07-31 1986-02-28 Procedimiento para la preparacion de derivados de acido 4-(isoxazolil)-tiazol-2-oxamico
ES552513A Expired ES8800217A1 (es) 1984-07-31 1986-02-28 Procedimiento para la preparacion de acidos 4-(isoxazolil)-tiazol-2-oxamicos y sus derivados

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES546420A Expired ES8608516A1 (es) 1984-07-31 1985-07-30 Procedimiento para la preparacion de acidos 4-isoxazolil- tiazol-2-oxamicos y sus derivados
ES546419A Expired ES8703459A1 (es) 1984-07-31 1985-07-30 Procedimiento para la preparacion de derivados de acido 4- (isoxazolil)-tiazol-2-oxamico

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES552513A Expired ES8800217A1 (es) 1984-07-31 1986-02-28 Procedimiento para la preparacion de acidos 4-(isoxazolil)-tiazol-2-oxamicos y sus derivados

Country Status (13)

Country Link
US (2) US4766138A (es)
EP (2) EP0191045B1 (es)
JP (2) JPS61502959A (es)
AU (2) AU583847B2 (es)
CA (2) CA1246583A (es)
DE (2) DE3574874D1 (es)
DK (2) DK142086A (es)
ES (4) ES8608516A1 (es)
FI (2) FI85473C (es)
IL (1) IL75981A (es)
IT (1) IT1183061B (es)
WO (2) WO1986000900A1 (es)
ZA (1) ZA855743B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1183061B (it) * 1984-07-31 1987-10-05 Zambon Spa Composti dotati di attivita'antiallergica
IT1204960B (it) * 1987-03-25 1989-03-10 Zambon Farmaceutici Spa Composti dotati di attivita' antiallergica
US4946963A (en) * 1987-11-13 1990-08-07 The University Of North Carolina At Chapel Hill Compounds for the control of hyperlipidemia using N-substituted isoxazolidine-3,5-diones
DE3844227A1 (de) * 1988-12-29 1990-07-05 Basf Ag 3(2h)-pyridazinonderivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung von schaedlingen
DE19625622A1 (de) * 1996-06-26 1998-01-02 Siemens Ag Lichtabstrahlendes Halbleiterbauelement mit Lumineszenzkonversionselement
CN1264228C (zh) 1996-06-26 2006-07-12 奥斯兰姆奥普托半导体股份有限两合公司 发光半导体器件、全色发光二极管显示装置及其应用
DE19638667C2 (de) 1996-09-20 2001-05-17 Osram Opto Semiconductors Gmbh Mischfarbiges Licht abstrahlendes Halbleiterbauelement mit Lumineszenzkonversionselement
CA2551611C (en) 2003-12-26 2013-06-25 Kyowa Hakko Kogyo Co., Ltd. Thiazole derivatives for treating or preventing parkinson's disease
EP1988077A4 (en) * 2006-02-23 2009-09-02 Shionogi & Co NUCLEIC HETEROCYCLIC DERIVATIVES SUBSTITUTED BY CYCLIC GROUPS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2429210A1 (fr) * 1978-06-19 1980-01-18 Fabre Sa Pierre Derives de phenyl-4 thiazolyl-2 oxamates utiles dans le traitement de l'asthme
DE3027527A1 (de) * 1980-07-19 1982-02-18 Basf Ag, 6700 Ludwigshafen Neue oxamidsaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel
FR2494272A1 (fr) * 1980-11-19 1982-05-21 Fabre Sa Pierre Derives de l'acide thiazolyl-2 oxamique substitues en position 4 par un radical thienyle ou furyle, leur preparation et leur utilisation comme medicaments
IT1183061B (it) * 1984-07-31 1987-10-05 Zambon Spa Composti dotati di attivita'antiallergica

Also Published As

Publication number Publication date
CA1243318A (en) 1988-10-18
AU4671785A (en) 1986-02-25
EP0190298B1 (en) 1989-10-18
ES546420A0 (es) 1986-07-16
FI861329L (fi) 1986-03-26
IT1183061B (it) 1987-10-05
IT8422150A0 (it) 1984-07-31
JPS61502896A (ja) 1986-12-11
ES546419A0 (es) 1987-02-16
EP0191045A1 (en) 1986-08-20
JPH0574592B2 (es) 1993-10-18
IT8422150A1 (it) 1986-01-31
DE3573781D1 (en) 1989-11-23
CA1246583A (en) 1988-12-13
WO1986000900A1 (en) 1986-02-13
DK164364B (da) 1992-06-15
DK142086D0 (da) 1986-03-26
IL75981A0 (en) 1985-12-31
EP0190298A1 (en) 1986-08-13
FI85473C (fi) 1992-04-27
AU4724885A (en) 1986-02-25
CA1261847C (es) 1989-09-26
JPH0576946B2 (es) 1993-10-25
DK141986D0 (da) 1986-03-26
DK141986A (da) 1986-05-28
AU584118B2 (en) 1989-05-18
EP0191045B1 (en) 1989-12-20
ES8800217A1 (es) 1987-10-16
JPS61502959A (ja) 1986-12-18
AU583847B2 (en) 1989-05-11
FI861330L (fi) 1986-03-26
ZA855743B (en) 1986-05-28
DK164364C (da) 1992-11-02
WO1986000899A1 (en) 1986-02-13
ES552514A0 (es) 1987-05-01
FI861329A0 (fi) 1986-03-26
DK142086A (da) 1986-05-29
FI861330A0 (fi) 1986-03-26
ES552513A0 (es) 1987-10-16
US4766138A (en) 1988-08-23
ES8608516A1 (es) 1986-07-16
DE3574874D1 (de) 1990-01-25
FI83650C (fi) 1991-08-12
ES8703459A1 (es) 1987-02-16
IL75981A (en) 1989-07-31
FI83650B (fi) 1991-04-30
FI85473B (fi) 1992-01-15
US4766137A (en) 1988-08-23

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519