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ES8606840A1 - Procedimiento para la preparacion de compuestos difluormetoxiaromaticos. - Google Patents

Procedimiento para la preparacion de compuestos difluormetoxiaromaticos.

Info

Publication number
ES8606840A1
ES8606840A1 ES540794A ES540794A ES8606840A1 ES 8606840 A1 ES8606840 A1 ES 8606840A1 ES 540794 A ES540794 A ES 540794A ES 540794 A ES540794 A ES 540794A ES 8606840 A1 ES8606840 A1 ES 8606840A1
Authority
ES
Spain
Prior art keywords
acid
racemic
ester
hydrolyzing
resolution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES540794A
Other languages
English (en)
Other versions
ES540794A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/410,805 external-priority patent/US4454344A/en
Priority claimed from US06/420,169 external-priority patent/US4407760A/en
Priority claimed from US06/420,170 external-priority patent/US4405529A/en
Priority claimed from US06/420,164 external-priority patent/US4404148A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of ES540794A0 publication Critical patent/ES540794A0/es
Publication of ES8606840A1 publication Critical patent/ES8606840A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/32—Separation; Purification; Stabilisation; Use of additives
    • C07C253/34—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/16—Preparation of ethers by reaction of esters of mineral or organic acids with hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE COMPUESTOS DIFLUORMETOXIAROMATICOS DE FORMULA (I). SE HACE REACCIONAR UN EQUIVALENTE MOLAR DE UN COMPUESTO DE FORMULA (II) DONDE R ES ALQUILO C1-C3, HALOGENO, NITRO O -CHR1-CH(CH3)2 DONDE R1 ES CN, COOR2, OH U OR3, A UNA TEMPERATURA QUE VARIA APROXIMADAMENTE ENTRE 20 Y 40JC, EN UNA MEZCLA DISOLVENTE DE 2-PROPANOL:ACETONITRILO O 2-PROPANOL:ACETONA, EN RELACIONES DE VOLUMEN 1:1 A 1:3, EN PRESENCIA DE AGUA, CON DOS O TRES EQUIVALENTES MOLARES DE CLORODIFLUORMETANO, AGREGADOS BAJO UNA PRESION DE 0,4 A 2,5 KG/CMC2, EN UN PERIODO DE TIEMPO QUE VARIA ENTRE APROXIMADAMENTE 30 MINUTOS A 3 HORAS Y CON UNA DISOLUCION ACUOSA DE UN HIDROXIDO DE METAL ALCALINO. UTILES EN LA FABRICACION DE PESTICIDAS PIRETROIDES.
ES540794A 1982-08-23 1985-02-28 Procedimiento para la preparacion de compuestos difluormetoxiaromaticos. Expired ES8606840A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/410,805 US4454344A (en) 1982-08-23 1982-08-23 Method for the resolution of racemic 2-(p-difluoromethoxyphenyl)-3-methylbutyric acid
US06/420,169 US4407760A (en) 1982-09-20 1982-09-20 Method for the preparation of difluoromethoxyaromatic compounds
US06/420,170 US4405529A (en) 1982-09-20 1982-09-20 Method for the preparation of difluoromethoxyaromatic compounds
US06/420,164 US4404148A (en) 1982-09-20 1982-09-20 Method for the preparation of difluoromethoxyaromatic compounds

Publications (2)

Publication Number Publication Date
ES540794A0 ES540794A0 (es) 1986-05-16
ES8606840A1 true ES8606840A1 (es) 1986-05-16

Family

ID=27503586

Family Applications (3)

Application Number Title Priority Date Filing Date
ES525084A Expired ES8505635A1 (es) 1982-08-23 1983-08-22 Un metodo para aislar acido 2-(p-difluormetoxifenil)-3-metilbutirico dextro-rotativo.
ES540795A Granted ES540795A0 (es) 1982-08-23 1985-02-28 Procedimiento para racemizar e hidrolizar esteres de alquilo de acido (-)-2-(4-difluormetoxifenil)-3-metilbutirico.
ES540794A Expired ES8606840A1 (es) 1982-08-23 1985-02-28 Procedimiento para la preparacion de compuestos difluormetoxiaromaticos.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES525084A Expired ES8505635A1 (es) 1982-08-23 1983-08-22 Un metodo para aislar acido 2-(p-difluormetoxifenil)-3-metilbutirico dextro-rotativo.
ES540795A Granted ES540795A0 (es) 1982-08-23 1985-02-28 Procedimiento para racemizar e hidrolizar esteres de alquilo de acido (-)-2-(4-difluormetoxifenil)-3-metilbutirico.

Country Status (7)

Country Link
EP (1) EP0101570B1 (es)
KR (1) KR910006003B1 (es)
BR (1) BR8304515A (es)
DE (1) DE3375478D1 (es)
ES (3) ES8505635A1 (es)
IE (1) IE55799B1 (es)
IL (1) IL69304A0 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01503541A (ja) * 1987-06-01 1989-11-30 ザ　ダウ　ケミカル　カンパニー ヒドロキシ芳香族化合物のプロパルギルエーテルの製造方法
DE4317322A1 (de) * 1993-05-25 1994-12-01 Bayer Ag Verfahren zur Herstellung von Difluormethoxy- und Difluormethylhioarenen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR74446B (es) * 1978-03-20 1984-06-28 American Cyanamid Co

Also Published As

Publication number Publication date
ES8602592A1 (es) 1985-12-01
IL69304A0 (en) 1983-11-30
BR8304515A (pt) 1984-04-03
IE831739L (en) 1984-02-23
ES525084A0 (es) 1985-06-01
ES540794A0 (es) 1986-05-16
EP0101570B1 (en) 1988-01-27
IE55799B1 (en) 1991-01-16
DE3375478D1 (en) 1988-03-03
KR910006003B1 (ko) 1991-08-09
KR840006000A (ko) 1984-11-21
EP0101570A1 (en) 1984-02-29
ES540795A0 (es) 1985-12-01
ES8505635A1 (es) 1985-06-01

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