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ES8606325A1 - Procedimiento para preparar compuestos de 3-amino-2,3-dihi- dro-1-benzoxepina - Google Patents

Procedimiento para preparar compuestos de 3-amino-2,3-dihi- dro-1-benzoxepina

Info

Publication number
ES8606325A1
ES8606325A1 ES548497A ES548497A ES8606325A1 ES 8606325 A1 ES8606325 A1 ES 8606325A1 ES 548497 A ES548497 A ES 548497A ES 548497 A ES548497 A ES 548497A ES 8606325 A1 ES8606325 A1 ES 8606325A1
Authority
ES
Spain
Prior art keywords
compounds
amino
dihydro
benzoxepine
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES548497A
Other languages
English (en)
Other versions
ES548497A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Products GmbH
Original Assignee
Kali Chemie Pharma GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma GmbH filed Critical Kali Chemie Pharma GmbH
Publication of ES8606325A1 publication Critical patent/ES8606325A1/es
Publication of ES548497A0 publication Critical patent/ES548497A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS DE 3-AMINO-2,3-DIHIDRO-1-BENZOXEPINA Y DE SUS SALES DE ADICION DE ACIDOS, DE FORMULA (I), EN LA QUE R1 Y R2 Y R4 PUEDEN SER VARIOS TIPOS DE RADICALES; Y R3 REPRESENTA HIDROGENO O UN GRUPO ALQUILO INFERIOR. CONSISTE EN LA REACCION DE ELIMINACION DE AGUA DE COMPUESTOS DE FORMULA (II), EN LA QUE TODOS LOS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I); SEGUIDA DE LA EVENTUAL TRANSFORMACION DEL COMPUESTO LIBRE EN LA SAL CORRESPONDIENTE. LA ELIMINACION DE AGUA SE LLEVA A CABO POR TRATAMIENTO CON UN ACIDO FUERTE, A UNA TEMPERATURA COMPRENDIDA ENTRE LA AMBIENTE Y LA DE EBULLICION DE LA MEZCLA DE REACCION. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE ESTADOS PATOLOGICOS DEPRESIVOS.
ES548497A 1984-11-05 1985-11-04 Procedimiento para preparar compuestos de 3-amino-2,3-dihi- dro-1-benzoxepina Expired ES8606325A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843440296 DE3440296A1 (de) 1984-11-05 1984-11-05 3-amino-2,3-dihydro-1-benzoxepin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
ES8606325A1 true ES8606325A1 (es) 1986-03-16
ES548497A0 ES548497A0 (es) 1986-03-16

Family

ID=6249484

Family Applications (1)

Application Number Title Priority Date Filing Date
ES548497A Expired ES8606325A1 (es) 1984-11-05 1985-11-04 Procedimiento para preparar compuestos de 3-amino-2,3-dihi- dro-1-benzoxepina

Country Status (19)

Country Link
US (1) US4672062A (es)
EP (1) EP0180889B1 (es)
JP (1) JPH0641461B2 (es)
AT (1) ATE43839T1 (es)
AU (1) AU579416B2 (es)
CA (1) CA1254893A (es)
DD (1) DD238049A5 (es)
DE (2) DE3440296A1 (es)
DK (1) DK506885A (es)
ES (1) ES8606325A1 (es)
FI (1) FI854343L (es)
GR (1) GR852638B (es)
HU (1) HU194205B (es)
IL (1) IL76936A (es)
NO (1) NO854392L (es)
NZ (1) NZ214066A (es)
PH (1) PH22384A (es)
PT (1) PT81422B (es)
ZA (1) ZA858376B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2169134B (en) * 1984-11-16 1988-11-16 Canon Kk Multibeam emitting device

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1593760A1 (de) * 1967-02-01 1972-06-08 Boehringer Sohn Ingelheim Verfahren zur Herstellung neuer Benz-epinderivate
DE2931398A1 (de) * 1979-08-02 1981-02-26 Kali Chemie Pharma Gmbh Neue 1-benzoxepin-5(2h)-on-derivate und ihre salze, verfahren und zwischenprodukte zu deren herstellung und diese verbindungen enthaltende arzneimittel
DE2931399A1 (de) * 1979-08-02 1981-02-26 Kali Chemie Pharma Gmbh Neue 3-amino-1-benzoxepin-derivate und ihre salze, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
DE3440295A1 (de) * 1984-11-05 1986-05-15 Kali-Chemie Pharma Gmbh, 3000 Hannover Verfahren zur diastereoselektiven reduktion von 3-amino-1-benzoxepin-5(2h)-onen

Also Published As

Publication number Publication date
EP0180889A3 (en) 1987-08-19
FI854343A7 (fi) 1986-05-06
ATE43839T1 (de) 1989-06-15
AU4934685A (en) 1986-05-15
PH22384A (en) 1988-08-12
GR852638B (es) 1986-03-04
US4672062A (en) 1987-06-09
EP0180889B1 (de) 1989-06-07
FI854343L (fi) 1986-05-06
NZ214066A (en) 1988-04-29
DK506885A (da) 1986-05-06
FI854343A0 (fi) 1985-11-05
HUT39173A (en) 1986-08-28
EP0180889A2 (de) 1986-05-14
PT81422A (en) 1985-11-01
ZA858376B (en) 1986-07-30
DE3570877D1 (en) 1989-07-13
ES548497A0 (es) 1986-03-16
AU579416B2 (en) 1988-11-24
NO854392L (no) 1986-05-06
IL76936A0 (en) 1986-04-29
DK506885D0 (da) 1985-11-04
HU194205B (en) 1988-01-28
IL76936A (en) 1989-01-31
DE3440296A1 (de) 1986-05-15
JPS61178979A (ja) 1986-08-11
DD238049A5 (de) 1986-08-06
CA1254893A (en) 1989-05-30
JPH0641461B2 (ja) 1994-06-01
PT81422B (en) 1987-07-31

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