ES8606254A1 - Procedimiento de obtencion de derivados del acido p-amino benzoico de interes terapeutico - Google Patents
Procedimiento de obtencion de derivados del acido p-amino benzoico de interes terapeuticoInfo
- Publication number
- ES8606254A1 ES8606254A1 ES543774A ES543774A ES8606254A1 ES 8606254 A1 ES8606254 A1 ES 8606254A1 ES 543774 A ES543774 A ES 543774A ES 543774 A ES543774 A ES 543774A ES 8606254 A1 ES8606254 A1 ES 8606254A1
- Authority
- ES
- Spain
- Prior art keywords
- prepn
- para
- amino
- benzoic acid
- acid derivs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ALYNCZNDIQEVRV-UHFFFAOYSA-N 4-aminobenzoic acid Chemical compound NC1=CC=C(C(O)=O)C=C1 ALYNCZNDIQEVRV-UHFFFAOYSA-N 0.000 title 2
- JNVGBRQYZHTBTP-UHFFFAOYSA-N 5-[(4-carboxyphenyl)diazenyl]-2-hydroxybenzoic acid Chemical compound C1=CC(C(=O)O)=CC=C1N=NC1=CC=C(O)C(C(O)=O)=C1 JNVGBRQYZHTBTP-UHFFFAOYSA-N 0.000 abstract 1
- TUCNEACPLKLKNU-UHFFFAOYSA-N acetyl Chemical compound C[C]=O TUCNEACPLKLKNU-UHFFFAOYSA-N 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 150000002892 organic cations Chemical class 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 238000009938 salting Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DEL ACIDO P-AMINOBENZOICO, DE FORMULA (I), EN LA QUE R1 ES UN CATION, ORGANICO O INORGANICO; Y R2 ES HIDROGENO O GRUPO CH3CO. CONSISTE EN LA REACCION DEL ACIDO SALICILAZOBENZOICO, QUE SE HALLA ACETILADO O SIN ACETILAR, CON UNA CANTIDAD EQUIVALENTE DE UNA BASE INORGANICA U ORGANICA ADECUADA. LA REACCION SE LLEVA A CABO EN MEDIO ACUOSO, A LA TEMPERATURA DE REFLUJO DE LA MEZCLA DE REACCION, Y LA SAL FORMADA SE SEPARA MEDIANTE SALADO O POR MEZCLA DE LA DISOLUCION ACUOSA OBTENIDA CON UN DISOLVENTE ORGANICO MISCIBLE. ESTOS COMPUESTOS TIENEN APLICACIONES PARA EL TRATAMIENTO DE LA COLITIS ULCEROSA.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES543774A ES8606254A1 (es) | 1985-05-31 | 1985-05-31 | Procedimiento de obtencion de derivados del acido p-amino benzoico de interes terapeutico |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES543774A ES8606254A1 (es) | 1985-05-31 | 1985-05-31 | Procedimiento de obtencion de derivados del acido p-amino benzoico de interes terapeutico |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES543774A0 ES543774A0 (es) | 1986-04-01 |
| ES8606254A1 true ES8606254A1 (es) | 1986-04-01 |
Family
ID=8489312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES543774A Expired ES8606254A1 (es) | 1985-05-31 | 1985-05-31 | Procedimiento de obtencion de derivados del acido p-amino benzoico de interes terapeutico |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES8606254A1 (es) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002018324A3 (en) * | 2000-08-29 | 2002-08-29 | Nobex Corp | Immunoregulatory compounds, derivatives thereof and their use |
| US7932366B2 (en) | 2004-07-07 | 2011-04-26 | Biocon Limited | Synthesis of azo bonded immunoregulatory compounds |
| US8048924B2 (en) | 2001-08-29 | 2011-11-01 | Biocon Limited | Methods and compositions employing 4-aminophenylacetic acid compounds |
-
1985
- 1985-05-31 ES ES543774A patent/ES8606254A1/es not_active Expired
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002018324A3 (en) * | 2000-08-29 | 2002-08-29 | Nobex Corp | Immunoregulatory compounds, derivatives thereof and their use |
| US7425578B2 (en) | 2000-08-29 | 2008-09-16 | Biocon Limited | Immunoregulatory compounds and derivatives and methods of treating diseases therewith |
| US8048924B2 (en) | 2001-08-29 | 2011-11-01 | Biocon Limited | Methods and compositions employing 4-aminophenylacetic acid compounds |
| US7932366B2 (en) | 2004-07-07 | 2011-04-26 | Biocon Limited | Synthesis of azo bonded immunoregulatory compounds |
| US8314214B2 (en) | 2004-07-07 | 2012-11-20 | Biocon Limited | Synthesis of azo bonded immunoregulatory compounds |
| US8754197B2 (en) | 2004-07-07 | 2014-06-17 | Biocon Limited | Synthesis of azo bonded immunoregulatory compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| ES543774A0 (es) | 1986-04-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970612 |