ES8601208A1 - Procedimiento de preparacion de un derivado de piracina. - Google Patents
Procedimiento de preparacion de un derivado de piracina.Info
- Publication number
- ES8601208A1 ES8601208A1 ES537947A ES537947A ES8601208A1 ES 8601208 A1 ES8601208 A1 ES 8601208A1 ES 537947 A ES537947 A ES 537947A ES 537947 A ES537947 A ES 537947A ES 8601208 A1 ES8601208 A1 ES 8601208A1
- Authority
- ES
- Spain
- Prior art keywords
- prepn
- gastric secretion
- pyrazine derivative
- secretion inhibitor
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003216 pyrazines Chemical class 0.000 title 1
- 239000002731 stomach secretion inhibitor Substances 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
- 239000005708 Sodium hypochlorite Substances 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000007800 oxidant agent Substances 0.000 abstract 1
- SUKJFIGYRHOWBL-UHFFFAOYSA-N sodium hypochlorite Chemical compound [Na+].Cl[O-] SUKJFIGYRHOWBL-UHFFFAOYSA-N 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO DE PREPARACION DE UN DERIVADO DE PIRACINA DE FORMULA (I). SE HACE REACCIONAR UNA AMIDA DE FORMULA (II) CON UN OXIDANTE COMO HIPOCLORITO SODICO HIPOBROMITO SODICO O TETRAACETATO DE PLOMO EN EL SENO DE UN DISOLVENTE COMO AGUA DIOXANO TETRAHIDROFURANO NN-DIMETIL FORMAMIDA O MEZCLAS DE LOS MISMOS Y A UNA TEMPERATURA COMPRENDIDA ENTRE 20 Y 125º C PARA OBTENER EL COMPUESTO (III) QUE POSTERIORMENTE SE HIDROLIZA EN AGUA DANDO EL COMPUESTO DESEADO. ES UN INHIBIDOR DE LA SECRECION GASTRICA Y UN CITOPROTECTOR.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES537947A ES8601208A1 (es) | 1984-11-26 | 1984-11-26 | Procedimiento de preparacion de un derivado de piracina. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES537947A ES8601208A1 (es) | 1984-11-26 | 1984-11-26 | Procedimiento de preparacion de un derivado de piracina. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES537947A0 ES537947A0 (es) | 1985-11-01 |
| ES8601208A1 true ES8601208A1 (es) | 1985-11-01 |
Family
ID=8488198
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES537947A Expired ES8601208A1 (es) | 1984-11-26 | 1984-11-26 | Procedimiento de preparacion de un derivado de piracina. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES8601208A1 (es) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015018808A1 (de) * | 2013-08-08 | 2015-02-12 | Bayer Pharma Aktiengesellschaft | Substituierte imidazo[1,2-a]pyrazincarboxamide und ihre verwendung |
| US9505786B2 (en) | 2012-01-11 | 2016-11-29 | Bayer Pharma Aktiengesellschaft | Substituted annulated triazines and use thereof |
| US9605008B2 (en) | 2013-07-10 | 2017-03-28 | Bayer Pharma Aktiengesellschaft | Benzyl-1H-pyrazolo[3,4-b]pyridines and use thereof |
-
1984
- 1984-11-26 ES ES537947A patent/ES8601208A1/es not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9505786B2 (en) | 2012-01-11 | 2016-11-29 | Bayer Pharma Aktiengesellschaft | Substituted annulated triazines and use thereof |
| US9605008B2 (en) | 2013-07-10 | 2017-03-28 | Bayer Pharma Aktiengesellschaft | Benzyl-1H-pyrazolo[3,4-b]pyridines and use thereof |
| WO2015018808A1 (de) * | 2013-08-08 | 2015-02-12 | Bayer Pharma Aktiengesellschaft | Substituierte imidazo[1,2-a]pyrazincarboxamide und ihre verwendung |
Also Published As
| Publication number | Publication date |
|---|---|
| ES537947A0 (es) | 1985-11-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC1A | Transfer granted | ||
| FD1A | Patent lapsed |
Effective date: 20050510 |