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ES8507520A1 - Un procedimiento para la preparacion de nuevos compuestos de b-lactama - Google Patents

Un procedimiento para la preparacion de nuevos compuestos de b-lactama

Info

Publication number
ES8507520A1
ES8507520A1 ES532516A ES532516A ES8507520A1 ES 8507520 A1 ES8507520 A1 ES 8507520A1 ES 532516 A ES532516 A ES 532516A ES 532516 A ES532516 A ES 532516A ES 8507520 A1 ES8507520 A1 ES 8507520A1
Authority
ES
Spain
Prior art keywords
clavulanic
intermediates
acid derivatives
compounds
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES532516A
Other languages
English (en)
Other versions
ES532516A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES532516A0 publication Critical patent/ES532516A0/es
Publication of ES8507520A1 publication Critical patent/ES8507520A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrane Compounds (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE COMPUESTOS DE BBB-LACTAMA, DE FORMULA (I), O UNA SAL DE ESTER DE LOS MISMOS, DONDE Z ES NHCOOR6 O NH2, SIENDO R6 ALQUILO C1-6, ALQUENILO C2-6, ARILO O ARIL-ALQUILO C1-6, OPCIONALMENTE SUSTITUIDOS.CONSISTENTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) DONDE RX ES UN GRUPO DE BLOQUEO CARBOXI, COMO EL BENCILO, CON UN COMPUESTO R8OH DONDE R8 ES HIDROGENO, ALQUILO C1-6, ALQUENILO C2-6, ARILO O ARIL-ALQUILO C1-6, OPCIONALMENTE SUSTITUIDOS. POSTERIORMENTE SE PUEDE SEPARAR EL GRUPO PROTECTOR O CONVERTIR LA SAL EN EL ACIDO CARBOXILICO LIBRE, EN UN ESTER O EN OTRA SAL.
ES532516A 1982-09-11 1984-05-16 Un procedimiento para la preparacion de nuevos compuestos de b-lactama Expired ES8507520A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8225989 1982-09-11

Publications (2)

Publication Number Publication Date
ES532516A0 ES532516A0 (es) 1985-09-01
ES8507520A1 true ES8507520A1 (es) 1985-09-01

Family

ID=10532862

Family Applications (2)

Application Number Title Priority Date Filing Date
ES525469A Granted ES525469A0 (es) 1982-09-11 1983-09-08 Un procedimiento para la preparacion de un compuesto.
ES532516A Expired ES8507520A1 (es) 1982-09-11 1984-05-16 Un procedimiento para la preparacion de nuevos compuestos de b-lactama

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES525469A Granted ES525469A0 (es) 1982-09-11 1983-09-08 Un procedimiento para la preparacion de un compuesto.

Country Status (9)

Country Link
US (1) US4622177A (es)
EP (1) EP0104010B1 (es)
JP (1) JPS5967288A (es)
AU (1) AU1898183A (es)
CA (1) CA1200245A (es)
DE (1) DE3363281D1 (es)
ES (2) ES525469A0 (es)
GR (1) GR79667B (es)
ZA (1) ZA836693B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5203287A (en) * 1992-08-07 1993-04-20 Tommy Hasbun Oscillating piston engine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4562182A (en) * 1980-12-23 1985-12-31 Beecham Group P.L.C. Compounds containing beta-lactams
EP0068609A1 (en) * 1981-06-11 1983-01-05 Beecham Group Plc Derivatives of clavulanic acid, a process for their preparation and their use

Also Published As

Publication number Publication date
EP0104010B1 (en) 1986-04-30
JPS5967288A (ja) 1984-04-16
ES8603488A1 (es) 1985-12-16
ES532516A0 (es) 1985-09-01
AU1898183A (en) 1984-03-15
EP0104010A1 (en) 1984-03-28
ZA836693B (en) 1985-02-27
ES525469A0 (es) 1985-12-16
CA1200245A (en) 1986-02-04
US4622177A (en) 1986-11-11
GR79667B (es) 1984-10-31
DE3363281D1 (en) 1986-06-05

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19941006