[go: up one dir, main page]

ES8503008A1 - Un procedimiento para preparar un ester de acido carboxilico de un esteroide - Google Patents

Un procedimiento para preparar un ester de acido carboxilico de un esteroide

Info

Publication number
ES8503008A1
ES8503008A1 ES532905A ES532905A ES8503008A1 ES 8503008 A1 ES8503008 A1 ES 8503008A1 ES 532905 A ES532905 A ES 532905A ES 532905 A ES532905 A ES 532905A ES 8503008 A1 ES8503008 A1 ES 8503008A1
Authority
ES
Spain
Prior art keywords
esters preparation
steroid esters
improved
improved steroid
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES532905A
Other languages
English (en)
Other versions
ES532905A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leo AB
Original Assignee
Leo AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo AB filed Critical Leo AB
Publication of ES532905A0 publication Critical patent/ES532905A0/es
Publication of ES8503008A1 publication Critical patent/ES8503008A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0074—Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Amplifiers (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UN ESTER DE ACIDO CARBOXILICO DE ESTEROIDE.CONSISTE EN HACER REACCIONAR UN ACIDO CARBOXILICO, UN COMPUESTO HIDROXILICO ESTEROIDE CON ESQUELETO C40 COMO MAXIMO DE CICLOPENTANOFENANTRENO. LA REACCION SE REALIZA EN PRESENCIA DE CATALIZADORES FORMADOS POR UNA COMBINACION DE UNA 4-(AMINO TERCIARIO)-PIRIDINA Y UN ACIDO FUERTE COMO (SULFURICO, NITRICO O ACPERCLORICO); SE REALIZA EN UN DISOLVENTE ORGANICO INERTE Y QUE PUEDE SER HIDROCARBURO, ESTER O CETONA. EL COMPUESTO HIDROXILICO ESTEROIDE PUEDE ESTAR ENTRE ESTRADIOL, ESTRIOL, HIDROCORTISONA, TESTOSTERONA O PREDNISONA. EL ACIDO CARBOXILICO DE PESO MOLECULAR MAYOR QUE 100 Y DE C6 A C12.TIENE UTILIDAD COMO PARTE DE FARMACOS ANTITUMORALES Y HORMONALES DE ACTUACION A LARGO PLAZO.
ES532905A 1983-05-30 1984-05-29 Un procedimiento para preparar un ester de acido carboxilico de un esteroide Expired ES8503008A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8303031A SE8303031D0 (sv) 1983-05-30 1983-05-30 Improved steroid esters preparation

Publications (2)

Publication Number Publication Date
ES532905A0 ES532905A0 (es) 1985-02-01
ES8503008A1 true ES8503008A1 (es) 1985-02-01

Family

ID=20351375

Family Applications (1)

Application Number Title Priority Date Filing Date
ES532905A Expired ES8503008A1 (es) 1983-05-30 1984-05-29 Un procedimiento para preparar un ester de acido carboxilico de un esteroide

Country Status (18)

Country Link
US (1) US4537722A (es)
EP (1) EP0127829B1 (es)
JP (1) JPS6041696A (es)
AT (1) ATE32603T1 (es)
AU (1) AU560235B2 (es)
CA (1) CA1211430A (es)
DE (1) DE3469440D1 (es)
DK (1) DK162100C (es)
ES (1) ES8503008A1 (es)
FI (1) FI80710C (es)
GR (1) GR82048B (es)
HU (1) HU198217B (es)
IE (1) IE57425B1 (es)
IL (1) IL71870A (es)
NZ (1) NZ208174A (es)
PT (1) PT78661B (es)
SE (1) SE8303031D0 (es)
ZA (1) ZA843946B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776923A (en) * 1993-01-19 1998-07-07 Endorecherche, Inc. Method of treating or preventing osteoporosis by adminstering dehydropiandrosterone
ATE322271T1 (de) * 1993-01-19 2006-04-15 Endorech Inc Therapeutische verwendungen von dehydroepiandrosteron zur behandlung von verminderter libido und osteoporose
DE4433374A1 (de) * 1994-09-20 1996-03-21 Hoechst Ag 17-Desoxi-corticosteroid-21-/O/-Carbonsäure- ester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
US5892068A (en) * 1998-08-25 1999-04-06 Mcneil-Ppc, Inc. Preparation of sterol and stanol-esters
US6087522A (en) * 1999-10-12 2000-07-11 Fan Tech Corporation Silicone lanolin esters
ES2382609T3 (es) * 2004-01-16 2012-06-11 Cedarburg Pharmaceuticals, Inc. Exemestano y sus productos intermedios y métodos de preparación de los mismos
JP5579074B2 (ja) * 2008-11-10 2014-08-27 株式会社ブリヂストン 変性天然ゴム及びその製造方法、並びにそれを用いたゴム組成物及びタイヤ

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1050883A (es) *
DE1958954C3 (de) * 1969-11-24 1978-11-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Veresterung von Alkoholen
US3678082A (en) * 1970-07-30 1972-07-18 Searle & Co Esterification of 17-hydroxy steroids
GB1558472A (en) * 1976-01-22 1980-01-03 Leo Ab 17-esters of 17- hydroxy gestogens
GB1565680A (en) * 1976-12-31 1980-04-23 Leo Ab Method for the preparation of carboxylic acid esters

Also Published As

Publication number Publication date
JPS6041696A (ja) 1985-03-05
AU2883284A (en) 1984-12-06
GR82048B (es) 1984-12-12
IE841192L (en) 1984-11-30
FI842164A0 (fi) 1984-05-30
ZA843946B (en) 1984-12-24
PT78661A (en) 1984-06-01
FI80710C (fi) 1990-07-10
DK265484D0 (da) 1984-05-29
EP0127829B1 (en) 1988-02-24
IL71870A (en) 1986-10-31
DK265484A (da) 1984-12-01
SE8303031D0 (sv) 1983-05-30
ATE32603T1 (de) 1988-03-15
DK162100C (da) 1992-02-24
ES532905A0 (es) 1985-02-01
DE3469440D1 (en) 1988-03-31
NZ208174A (en) 1987-04-30
US4537722A (en) 1985-08-27
HUT34222A (en) 1985-02-28
EP0127829A2 (en) 1984-12-12
DK162100B (da) 1991-09-16
FI80710B (fi) 1990-03-30
CA1211430A (en) 1986-09-16
HU198217B (en) 1989-08-28
IL71870A0 (en) 1984-09-30
FI842164L (fi) 1984-12-01
AU560235B2 (en) 1987-04-02
JPH0369360B2 (es) 1991-10-31
PT78661B (en) 1986-06-26
IE57425B1 (en) 1992-09-09
EP0127829A3 (en) 1985-08-07

Similar Documents

Publication Publication Date Title
NZ236589A (en) A-nor-steroid-3-carboxylic acid derivatives and pharmaceutical compositions
IL77396A (en) Pharmaceutical compositions containing bicyclic heteroarylpiperazine derivatives,certain such novel compounds and their preparation
AU571225B2 (en) Retro-inverso analogues of the bradykinin potentiating peptide bpp 5a
DE69432109D1 (de) Synthetische, vielfache tandemwiederholungen des mucinpeptides und seiner derivate und deren verwendung
ZA822887B (en) Process for producing ethylene glycol and/or glycolic acid ester,catalyst composition used therefor,and process for production thereof
ES8502417A1 (es) "un procedimiento para obtener de orina una fraccion que contiene un ingrediente antineoplastico de naturaleza peptidica".
ES8503008A1 (es) Un procedimiento para preparar un ester de acido carboxilico de un esteroide
ES8401960A1 (es) Procedimiento para la preparacion de imidazolilfenil-tetrahidropiridazinas.
ES8203897A1 (es) Procedimiento para la obtencion de imidazoazoalquenamidas
EP0642507A4 (en) Catalytic antibodies against cocaine and methods of using and producing same.
AU7242687A (en) Nucleic acid and methods for the synthesis of novel DAF compositions
AU4554396A (en) Superior thrombomodulin analogs for pharmaceutical use
IE46290L (en) Improved method of preparing carboxylic acid esters
DE69631169D1 (de) Herstellung von (s)-decahydroisochinolin-3-carbonsäure-t-butylamid
EP0103125A3 (en) Aliphatic dicarboxylic acid esters as perfuming agents, and perfume compositions and perfumed products containing them
ES8505351A1 (es) Un procedimiento para preparar nuevas aroilimidazolonas
ES8600768A1 (es) Imidazotiadiazolalquencarboxiamidas
AU586329B2 (en) Primary hindered aminoacids for promoted acid gas scrubbing process
ZA876354B (en) Process and intermediates for n-(s-3-alkylheptanoyl)-d-gamma-glutamyl-d-alanine
ATE29734T1 (de) Verwendung von salicylsaeureestern als riechstoffe und diese enthaltende riechstoffkompositionen.

Legal Events

Date Code Title Description
PC1A Transfer granted
PC1A Transfer granted