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ES8401083A1 - New organic compounds processes for their production and their use - Google Patents

New organic compounds processes for their production and their use

Info

Publication number
ES8401083A1
ES8401083A1 ES513539A ES513539A ES8401083A1 ES 8401083 A1 ES8401083 A1 ES 8401083A1 ES 513539 A ES513539 A ES 513539A ES 513539 A ES513539 A ES 513539A ES 8401083 A1 ES8401083 A1 ES 8401083A1
Authority
ES
Spain
Prior art keywords
formula
production
organic compounds
new organic
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES513539A
Other languages
Spanish (es)
Other versions
ES513539A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES513539A0 publication Critical patent/ES513539A0/en
Publication of ES8401083A1 publication Critical patent/ES8401083A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DEL ACIDO CEFALOESPORANICO Y DE SUS SALES, DE FORMULA (I), EN LA QUE R1, R2, R3 Y R4 PUEDEN SER VARIOS TIPOS DE RADICALES.CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), O UN DERIVADO REACTIVO DEL MISMO, EN LAS QUE R5 ES HIDROGENO O UN GRUPO PROTECTOR DE AMINO, R2 ES EL MISMO QUE R2 SALVO CARBOXIALQUILO, Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE EFECTUA EN UN DISOLVENTE INERTE, EN PRESENCIA DE UN AGENTE DE CONDENSACION, A UNA TEMPERATURAENTRE -20JC Y LA AMBIENTE.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTIMICROBIANA.PROCEDURE FOR OBTAINING DERIVATIVES OF CEPHALOSPORANIC ACID AND ITS SALTS, OF FORMULA (I), IN WHICH R1, R2, R3 AND R4 CAN BE VARIOUS TYPES OF RADICALS. IT CONSISTS OF THE REACTION OF A COMPOUND OF FORMULA (II) WITH A COMPOUND OF FORMULA (III), OR A REACTIVE DERIVATIVE THEREOF, IN WHICH R5 IS HYDROGEN OR AN AMINO PROTECTING GROUP, R2 IS THE SAME AS R2 EXCEPT CARBOXYALKYL, AND ALL OTHER SYMBOLS HAVE THE SAME MEANING AS IN FORMULA ( YO). THE REACTION IS CARRIED OUT IN AN INERT SOLVENT, IN THE PRESENCE OF A CONDENSATION AGENT, AT A TEMPERATURE BETWEEN -20 JC AND AMBIENT. THESE COMPOUNDS HAVE PHARMACOLOGICAL APPLICATIONS DUE TO THEIR ANTIMICROBIAL ACTIVITY.

ES513539A 1981-06-29 1982-06-28 New organic compounds processes for their production and their use Expired ES8401083A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH427481 1981-06-29

Publications (2)

Publication Number Publication Date
ES513539A0 ES513539A0 (en) 1983-12-01
ES8401083A1 true ES8401083A1 (en) 1983-12-01

Family

ID=4273043

Family Applications (1)

Application Number Title Priority Date Filing Date
ES513539A Expired ES8401083A1 (en) 1981-06-29 1982-06-28 New organic compounds processes for their production and their use

Country Status (15)

Country Link
JP (1) JPS5815983A (en)
AU (1) AU8539182A (en)
BE (1) BE893576A (en)
DE (1) DE3223019A1 (en)
DK (1) DK290882A (en)
ES (1) ES8401083A1 (en)
FI (1) FI822244A7 (en)
FR (3) FR2508458A1 (en)
GB (1) GB2100734A (en)
IL (1) IL66148A0 (en)
IT (1) IT1186693B (en)
NL (1) NL8202580A (en)
PT (1) PT75139B (en)
SE (1) SE8203988L (en)
ZA (1) ZA824647B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59155391A (en) * 1983-02-22 1984-09-04 Tanabe Seiyaku Co Ltd New cephalosporin derivatives
GB8722477D0 (en) * 1987-09-24 1987-10-28 Beecham Group Plc Compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB567353A (en) * 1943-08-27 1945-02-09 John David Kendall Improvements in the manufacture of tetrazole compounds
DE2760484C2 (en) * 1976-04-14 1992-12-03 Takeda Chemical Industries, Ltd., Osaka, Jp
JPS6011713B2 (en) * 1976-09-08 1985-03-27 武田薬品工業株式会社 Cephalosporin derivatives and their production method
DE2714880A1 (en) * 1977-04-02 1978-10-26 Hoechst Ag CEPHEMDER DERIVATIVES AND PROCESS FOR THEIR PRODUCTION

Also Published As

Publication number Publication date
AU8539182A (en) 1983-01-06
SE8203988D0 (en) 1982-06-28
IT8248704A1 (en) 1983-12-25
SE8203988L (en) 1982-12-30
FR2511002A1 (en) 1983-02-11
PT75139B (en) 1985-01-07
ES513539A0 (en) 1983-12-01
PT75139A (en) 1982-07-01
NL8202580A (en) 1983-01-17
FI822244L (en) 1982-12-30
FI822244A0 (en) 1982-06-22
FR2510999A1 (en) 1983-02-11
GB2100734A (en) 1983-01-06
IT8248704A0 (en) 1982-06-25
IT1186693B (en) 1987-12-04
DE3223019A1 (en) 1983-01-05
FR2508458A1 (en) 1982-12-31
JPS5815983A (en) 1983-01-29
DK290882A (en) 1982-12-30
IL66148A0 (en) 1982-09-30
BE893576A (en) 1982-12-21
FI822244A7 (en) 1982-12-30
ZA824647B (en) 1984-02-29

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