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ES8401067A1 - Procedimiento analogo para preparar un derivado de tropil benzoato. - Google Patents

Procedimiento analogo para preparar un derivado de tropil benzoato.

Info

Publication number
ES8401067A1
ES8401067A1 ES512925A ES512925A ES8401067A1 ES 8401067 A1 ES8401067 A1 ES 8401067A1 ES 512925 A ES512925 A ES 512925A ES 512925 A ES512925 A ES 512925A ES 8401067 A1 ES8401067 A1 ES 8401067A1
Authority
ES
Spain
Prior art keywords
migraine
treatment
benzoate derivatives
hydrogen
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES512925A
Other languages
English (en)
Other versions
ES512925A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merrell Toraude et Cie
Original Assignee
Merrell Toraude et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Toraude et Cie filed Critical Merrell Toraude et Cie
Publication of ES8401067A1 publication Critical patent/ES8401067A1/es
Publication of ES512925A0 publication Critical patent/ES512925A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/12—Oxygen atoms acylated by aromatic or heteroaromatic carboxylic acids, e.g. cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UN DERIVADO DE TROPIL BENZOATO.SE HACE REACCIONAR TROPINA Y UN HALURO ACIDO; PARA ELLO SE CALIENTE UNA SAL DE HIDROHALURO DE TROPINA CON EL HALURO ACIDO EN AUSENCIA DE UN DISOLVENTE. SE OBTIENE EL COMPUESTO (I) EN EL QUE R1 ES ALQUILO C1-4; ALCOXI C1-4 O HALOGENO; R2 ES HIDROGENO, ALQUILO C1-4, ALCOXI C1-4 O HALOGENO; R2 ES HIDROGENO, ALQUILO C1-4, ALCOXI C1-4 O HALOGENO; R3 ES HIDROGENO, ALQUILO C1-4, ALCOXI C1-4 O HALOGENO. R3 DEBE SER HIDROGENO CUANDO R2 ES HIDROGENO.
ES512925A 1981-06-13 1982-06-08 Procedimiento analogo para preparar un derivado de tropil benzoato. Granted ES512925A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8118249 1981-06-13

Publications (2)

Publication Number Publication Date
ES8401067A1 true ES8401067A1 (es) 1983-12-01
ES512925A0 ES512925A0 (es) 1983-12-01

Family

ID=10522493

Family Applications (1)

Application Number Title Priority Date Filing Date
ES512925A Granted ES512925A0 (es) 1981-06-13 1982-06-08 Procedimiento analogo para preparar un derivado de tropil benzoato.

Country Status (9)

Country Link
US (1) US4563465A (es)
EP (1) EP0067770B1 (es)
JP (1) JPS58978A (es)
AT (1) ATE71525T1 (es)
AU (1) AU549640B2 (es)
CA (1) CA1220141A (es)
DE (1) DE3280390D1 (es)
ES (1) ES512925A0 (es)
ZA (1) ZA823884B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
JPS5936675A (ja) * 1982-07-13 1984-02-28 サンド・アクチエンゲゼルシヤフト 二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド
WO1985001048A1 (en) * 1983-08-26 1985-03-14 Sandoz Ag Aromatic esters or amides of carboxylic acid and sulfonic acid
FR2557110B1 (fr) * 1983-12-23 1989-11-24 Sandoz Sa Nouveaux derives d'amines cycliques, leur preparation et leur utilisation comme medicaments
CH667657A5 (de) * 1985-01-07 1988-10-31 Sandoz Ag Carbocyclische und heterocyclische carbonylmethylen- und methylpiperidine und -pyrrolidine.
GB8518658D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Medicaments
US4906755A (en) * 1986-11-03 1990-03-06 Merrell Dow Pharmaceuticals Inc. Esters of hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3-(4H)-one and related compounds
GB8701022D0 (en) * 1987-01-19 1987-02-18 Beecham Group Plc Treatment
US5166341A (en) * 1988-07-29 1992-11-24 Dainippon Pharmaceutical Co., Ltd. 6-amino-1,4-hexahydro-1H-diazepine derivatives
US5017573A (en) * 1988-07-29 1991-05-21 Dainippon Pharmaceutical Co., Ltd. Indazole-3-carboxylic acid derivatives
US5126343A (en) * 1989-09-11 1992-06-30 G. D. Searle & Co. N-azabicyclo [3.3.0]octane amides of aromatic acids
CA2030051C (en) * 1989-11-17 2001-08-07 Haruhiko Kikuchi Indole derivatives
JP3026845B2 (ja) * 1991-02-20 2000-03-27 日清製粉株式会社 ピペリジン誘導体
US5460972A (en) * 1991-04-08 1995-10-24 Research Foundation Of The State University Of New York Ionized magnesium2+ concentrations in biological samples
JP2541231Y2 (ja) * 1992-10-06 1997-07-16 彦夫 望月 脚立用安全棒

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3170927A (en) * 1965-02-23 O chzoh

Also Published As

Publication number Publication date
AU549640B2 (en) 1986-02-06
ATE71525T1 (de) 1992-02-15
US4563465A (en) 1986-01-07
DE3280390D1 (de) 1992-02-27
EP0067770B1 (en) 1992-01-15
EP0067770A3 (en) 1983-04-06
ZA823884B (en) 1983-03-30
EP0067770A2 (en) 1982-12-22
AU8474982A (en) 1982-12-23
JPS58978A (ja) 1983-01-06
CA1220141A (en) 1987-04-07
ES512925A0 (es) 1983-12-01
JPH0239510B2 (es) 1990-09-05

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