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ES8307247A1 - "procedimiento para preparar nuevos derivados de 20,21-dinoreburnamenina". - Google Patents

"procedimiento para preparar nuevos derivados de 20,21-dinoreburnamenina".

Info

Publication number
ES8307247A1
ES8307247A1 ES516299A ES516299A ES8307247A1 ES 8307247 A1 ES8307247 A1 ES 8307247A1 ES 516299 A ES516299 A ES 516299A ES 516299 A ES516299 A ES 516299A ES 8307247 A1 ES8307247 A1 ES 8307247A1
Authority
ES
Spain
Prior art keywords
alkyl
hydrogen
vasoregulating
dinoreburnamenines
cerebral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES516299A
Other languages
English (en)
Other versions
ES516299A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES8307247A1 publication Critical patent/ES8307247A1/es
Publication of ES516299A0 publication Critical patent/ES516299A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D461/00Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR NUEVOS DERIVADOS DE 20,21-DINOREBURNAMENINA. CONSISTE EN SOMETER A DESHIDRATACION A UN COMPUESTO DE FORMULA GENERAL (II) EN QUE R ES UN ATOMO DE CARBONO O UN RADICAL ALCOHILO DE 1 A 4 ATOMOS DE CARBONO. SE OBTIENE EL COMPUESTO (I) EN QUE R ES HIDROGENO, UN RADICAL ALCOHILO CON 1 A 4 ATOMOS DE CARBONO O UN GRUPO =CH . EL TRAZO ONDULADO QUE UNE AL RADICAL R AL CICLO E REPRESENTA UN ENLACE SENCILLO CUANDO R ES HIDROGENO O UN RADICAL ALCOHILO; O UN DOBLE ENLACE CUANDO R ES UN GRUPO =CH .
ES516299A 1981-10-08 1982-10-07 "procedimiento para preparar nuevos derivados de 20,21-dinoreburnamenina". Granted ES516299A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8118935A FR2514357A1 (fr) 1981-10-08 1981-10-08 Nouveaux derives de 20,21-dinoreburnamenine eventuellement substitues sur le cycle e, procede de preparation et application comme medicaments

Publications (2)

Publication Number Publication Date
ES8307247A1 true ES8307247A1 (es) 1983-06-16
ES516299A0 ES516299A0 (es) 1983-06-16

Family

ID=9262847

Family Applications (1)

Application Number Title Priority Date Filing Date
ES516299A Granted ES516299A0 (es) 1981-10-08 1982-10-07 "procedimiento para preparar nuevos derivados de 20,21-dinoreburnamenina".

Country Status (19)

Country Link
US (1) US4501740A (es)
JP (1) JPH0651700B2 (es)
AT (1) AT385989B (es)
BE (1) BE894630A (es)
CA (1) CA1186311A (es)
CH (1) CH655319A5 (es)
DE (1) DE3237429A1 (es)
ES (1) ES516299A0 (es)
FR (1) FR2514357A1 (es)
GB (1) GB2107317B (es)
GR (1) GR77710B (es)
HU (1) HU188330B (es)
IT (1) IT1149103B (es)
LU (1) LU84412A1 (es)
MX (1) MX159206A (es)
NL (1) NL8203859A (es)
PT (1) PT75656B (es)
SE (1) SE452885B (es)
ZA (1) ZA827058B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2623501B1 (fr) * 1987-11-19 1990-03-16 Roussel Uclaf Nouveaux derives substitues de 20,21-dinoreburnamenine, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions pharmaceutiques les renfermant
FR2623503B1 (es) * 1987-11-19 1991-04-05 Roussel Uclaf
GB2219970B (en) * 1988-05-20 1992-09-16 Amada Co Ltd Cutting machine and method for positioning end of workpiece to be cut in cutting machine
FR2653124B1 (fr) * 1989-10-17 1992-01-17 Roussel Uclaf Nouveaux derives substitues en 15 de la 20, 21-dinoreburnamenine, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions les renfermant.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2168853B1 (es) * 1972-01-24 1975-04-25 Centre Etd Ind Pharma
US4033969A (en) * 1972-06-19 1977-07-05 Agence Nationale De Valorisation De La Recherche (Anvar) Vincamine derivatives
FR2190113A5 (es) * 1972-06-19 1974-01-25 Anvar
HU171663B (hu) * 1975-09-01 1978-02-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh 14-skobka-zamehhennogo metil-skobka zakryta-vinkana
HU173511B (hu) * 1976-07-21 1979-05-28 Richter Gedeon Vegyeszet Sposob poluchenija vinkamenina, ego solejj i molekuljarnykh soedinenijj
HU174214B (hu) * 1976-07-21 1979-11-28 Richter Gedeon Vegyeszet Sposob poluchenija vinkana i solejj
GB1568417A (en) * 1976-07-21 1980-05-29 Richter Gedeon Vegyeszet Vincamine derivatives
FR2381048A1 (fr) * 1977-02-22 1978-09-15 Roussel Uclaf Nouveaux derives de 20,21-dinoreburnamenine, un procede pour leur preparation et leur application comme medicaments
FR2475549A1 (fr) * 1980-02-12 1981-08-14 Synthelabo Derives vincaminiques desethyles, leur synthese et leur application en therapeutique

Also Published As

Publication number Publication date
LU84412A1 (fr) 1983-06-13
CH655319A5 (fr) 1986-04-15
AT385989B (de) 1988-06-10
DE3237429A1 (de) 1983-04-21
SE8205335D0 (sv) 1982-09-17
IT8249226A0 (it) 1982-10-07
IT1149103B (it) 1986-12-03
FR2514357B1 (es) 1984-12-28
GR77710B (es) 1984-09-25
CA1186311A (fr) 1985-04-30
ZA827058B (en) 1983-07-27
SE8205335L (sv) 1983-04-09
PT75656A (fr) 1982-11-01
GB2107317B (en) 1985-07-03
NL8203859A (nl) 1983-05-02
ATA373182A (de) 1987-11-15
JPH0651700B2 (ja) 1994-07-06
PT75656B (fr) 1986-04-09
MX159206A (es) 1989-05-02
JPS5872582A (ja) 1983-04-30
FR2514357A1 (fr) 1983-04-15
HU188330B (en) 1986-04-28
BE894630A (fr) 1983-04-07
SE452885B (sv) 1987-12-21
US4501740A (en) 1985-02-26
GB2107317A (en) 1983-04-27
ES516299A0 (es) 1983-06-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970612