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ES8306797A1 - A METHOD TO PRODUCE A POLYPEPTIDE. - Google Patents

A METHOD TO PRODUCE A POLYPEPTIDE.

Info

Publication number
ES8306797A1
ES8306797A1 ES511741A ES511741A ES8306797A1 ES 8306797 A1 ES8306797 A1 ES 8306797A1 ES 511741 A ES511741 A ES 511741A ES 511741 A ES511741 A ES 511741A ES 8306797 A1 ES8306797 A1 ES 8306797A1
Authority
ES
Spain
Prior art keywords
host
polypeptide
recombinant dna
dna molecule
cultivate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES511741A
Other languages
Spanish (es)
Other versions
ES511741A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biogen NV
Original Assignee
Biogen NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen NV filed Critical Biogen NV
Publication of ES8306797A1 publication Critical patent/ES8306797A1/en
Publication of ES511741A0 publication Critical patent/ES511741A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32111—Aphthovirus, e.g. footandmouth disease virus
    • C12N2770/32122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

UN METODO PARA PRODUCIR UN POLIPEPTIDO. CONSTA DE LAS SIGUIENTES ETAPAS: 1 ) PREPARAR UNA SECUENCIA DE ADN QUE CODIFICA EL POLIPEPTIDO, ESCINDIR UN VECTOR DE CLONACION, COMBINAR LA SECUENCIA DE ADN, EL VECTOR DE CLONACION Y UNA SECUENCIA DE CONTROL PARA FORMAR UNA MOLECULA DE ADN RECOMBINANTE, TRANSFORMACION DE UN HOSPEDANTE CON LA MOLECULA DE ADN RECOMBINANTE, CULTIVAR EL HOSPEDANTE TRANSFORMADO Y RECOGER EL POLIPEPTIDO. 2 ) TRANSFORMAR UN HOSPEDANTE CON UNA MOLECULA DE ADN RECOMBINANTE. 3 ) CULTIVAR UN HOSPEDANTE TRANSFORMADO. EL HOSPEDANTE EMPLEADO ES UN HOSPEDANTE BACILLUS.A METHOD FOR PRODUCING A POLYPEPTIDE. IT CONSISTS OF THE FOLLOWING STEPS: 1) PREPARE A DNA SEQUENCE ENCODING THE POLYPEPTIDE, EXCIDE A CLONING VECTOR, COMBINE THE DNA SEQUENCE, THE CLONING VECTOR AND A CONTROL SEQUENCE TO FORM A RECOMBINANT DNA MOLECULE, TRANSFORMATION OF A HOST WITH THE RECOMBINANT DNA MOLECULE, CULTIVATE THE TRANSFORMED HOST AND COLLECT THE POLYPEPTIDE. 2) TRANSFORM A HOST WITH A RECOMBINANT DNA MOLECULE. 3) CULTIVATE A TRANSFORMED HOST. THE HOST USED IS A BACILLUS HOST.

ES511741A 1981-04-29 1982-04-27 A METHOD TO PRODUCE A POLYPEPTIDE. Granted ES511741A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8113253 1981-04-29

Publications (2)

Publication Number Publication Date
ES8306797A1 true ES8306797A1 (en) 1983-06-01
ES511741A0 ES511741A0 (en) 1983-06-01

Family

ID=10521486

Family Applications (1)

Application Number Title Priority Date Filing Date
ES511741A Granted ES511741A0 (en) 1981-04-29 1982-04-27 A METHOD TO PRODUCE A POLYPEPTIDE.

Country Status (12)

Country Link
EP (1) EP0063953A3 (en)
JP (1) JPS57181099A (en)
AU (1) AU8300282A (en)
BR (1) BR8202422A (en)
DD (1) DD203331A5 (en)
DK (1) DK188582A (en)
ES (1) ES511741A0 (en)
FI (1) FI821466A7 (en)
GR (1) GR75411B (en)
NO (1) NO821391L (en)
PT (1) PT74811B (en)
ZA (1) ZA822855B (en)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA831854B (en) * 1982-03-26 1984-01-25 Biogen Nv Small peptides with the specificity of foot and mouth disease viral antigens
CA1224432A (en) * 1982-08-17 1987-07-21 Gary N. Buell Dna sequences, recombinant dna molecules and processes for producing bovine growth hormone-like polypeptides in high yield
IT1156317B (en) * 1982-09-08 1987-02-04 Anic Spa BACILLUS SUBTILIS EXPRESSION PLASMID VECTORS AND PROCEDURE FOR THEIR PREPARATION
US4559300A (en) * 1983-01-18 1985-12-17 Eli Lilly And Company Method for using an homologous bacillus promoter and associated natural or modified ribosome binding site-containing DNA sequence in streptomyces
US4783405A (en) * 1983-01-18 1988-11-08 Eli Lilly And Company Recombinant DNA expression vectors useful in bacillus and other host cells
US4595660A (en) * 1983-03-02 1986-06-17 University Of Delaware Molecular cloning with bifunctional plasmid vectors in Bacillus subtilis, mutants and substantially stably transformed mutants of Bacillus subtilis, and methods for utilizing the transformed mutants
US4649119A (en) * 1983-04-28 1987-03-10 Massachusetts Institute Of Technology Cloning systems for corynebacterium
US4663280A (en) * 1983-05-19 1987-05-05 Public Health Research Institute Of The City Of New York Expression and secretion vectors and method of constructing vectors
US4912046A (en) * 1983-06-27 1990-03-27 Genentech, Inc. Portable inducible control system
JPS6041697A (en) * 1983-08-15 1985-03-05 Asahi Chem Ind Co Ltd Novel synthesis method for active protein derivatives
JPS60137291A (en) * 1983-12-26 1985-07-20 Takeda Chem Ind Ltd Production of gene product
JPH0630583B2 (en) * 1984-01-27 1994-04-27 武田薬品工業株式会社 DIA and its uses
JPS60188093A (en) * 1984-03-09 1985-09-25 Teruhiko Beppu Plasmid expressing character in bacillus subtilis
IL71555A (en) * 1984-04-15 1992-06-21 State Of Israel Israel Inst Fo Bovine interferon
US5171673A (en) * 1988-07-18 1992-12-15 Biotechnica International, Inc. Expression of heterologous dna using the bacillus coagulans amylase gene
IE914102A1 (en) 1990-11-26 1992-06-03 Genetics Inst Expression of pace in host cells and methods of use thereof
ATE476508T1 (en) 1997-11-06 2010-08-15 Novartis Vaccines & Diagnostic NEISSERIAL ANTIGENS
SG152917A1 (en) 1998-01-14 2009-06-29 Chiron Srl Neisseria meningitidis antigens
GB9808932D0 (en) 1998-04-27 1998-06-24 Chiron Spa Polyepitope carrier protein
EP2261341A3 (en) 1998-05-01 2012-01-04 Novartis Vaccines and Diagnostics, Inc. Neisseria meningitidis antigens and compositions
EP1228217B1 (en) 1999-04-30 2012-11-21 Novartis Vaccines and Diagnostics S.r.l. Conserved neisserial antigens
GB9911683D0 (en) 1999-05-19 1999-07-21 Chiron Spa Antigenic peptides
GB9916529D0 (en) 1999-07-14 1999-09-15 Chiron Spa Antigenic peptides
EP2275552B1 (en) 1999-10-29 2015-09-09 GlaxoSmithKline Biologicals SA Neisserial antigenic peptides
EP2275129A3 (en) 2000-01-17 2013-11-06 Novartis Vaccines and Diagnostics S.r.l. Outer membrane vesicle (OMV) vaccine comprising N. meningitidis serogroup B outer membrane proteins
WO2002034771A2 (en) 2000-10-27 2002-05-02 Chiron Srl Nucleic acids and proteins from streptococcus groups a & b
GB0107658D0 (en) 2001-03-27 2001-05-16 Chiron Spa Streptococcus pneumoniae
GB0107661D0 (en) 2001-03-27 2001-05-16 Chiron Spa Staphylococcus aureus
MXPA04000653A (en) 2001-07-27 2004-11-22 Chiron Srl Meningococcus adhesins nada, app and orf 40.
ES2312649T3 (en) 2001-12-12 2009-03-01 Novartis Vaccines And Diagnostics S.R.L. IMMUNIZATION AGAINST CHLAMYDIA TRACHOMATIS.
EP1513945A4 (en) 2002-05-24 2008-12-24 Restoragen Inc Method for universal enzymatic production of bioactive peptides
AU2003243316A1 (en) 2002-05-24 2003-12-12 Nps Allelix Corp. Method for enzymatic production of glp-2(1-33) and glp-2-(1-34) peptides
US20070059329A1 (en) 2002-11-15 2007-03-15 Nathalie Norais Unexpected surface proteins in meningococcus
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
GB0308198D0 (en) 2003-04-09 2003-05-14 Chiron Srl ADP-ribosylating bacterial toxin
DK1704234T3 (en) 2003-11-21 2012-05-07 Nps Pharma Inc Preparation of glucagon-like peptide 2 and analogues
GB0524066D0 (en) 2005-11-25 2006-01-04 Chiron Srl 741 ii
WO2008020335A2 (en) 2006-06-09 2008-02-21 Novartis Ag Immunogenic compositions for streptococcus agalactiae
US9579372B2 (en) 2008-02-21 2017-02-28 Glaxosmithkline Biologicals Sa Meningococcal fHBP polypeptides
ITMI20090946A1 (en) 2009-05-28 2010-11-29 Novartis Ag EXPRESSION OF RECOMBINANT PROTEINS
BR112012004275A2 (en) 2009-08-27 2016-11-16 Novartis Ag hybrid polypeptides including meningococcal fhbp sequences
EP2493499A1 (en) 2009-10-27 2012-09-05 Novartis AG Modified meningococcal fhbp polypeptides
FR2954349A1 (en) 2009-12-22 2011-06-24 Agronomique Inst Nat Rech SULFATASE SELECTIVELY MODIFYING GLYCOSAMINOGLYCANS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2048894A (en) * 1979-05-11 1980-12-17 Gist Brocades Nv Plasmid
AU545912B2 (en) * 1980-03-10 1985-08-08 Cetus Corporation Cloned heterologous jive products in bacillies
FI64813C (en) * 1980-12-31 1984-01-10 Ilkka Antero Palva FOERFARANDE FOER PRODUCERING AV ETT UTVALT AEGGVITEAEMNE OCH VID FOERFARANDET ANVAENDA REKOMBINANTPLASMIDVEKTORER
EP0057496A3 (en) * 1981-01-06 1983-03-16 The Public Health Laboratory Service Board Chimeric plasmids
CA1204681A (en) * 1981-04-20 1986-05-20 Cetus Corporation Method and vector organism for controlled accumulation of cloned heterologous gene products in bacillus subtilis ii

Also Published As

Publication number Publication date
GR75411B (en) 1984-07-16
FI821466L (en) 1982-10-30
FI821466A0 (en) 1982-04-27
NO821391L (en) 1982-11-01
EP0063953A2 (en) 1982-11-03
DK188582A (en) 1982-10-30
AU8300282A (en) 1982-11-04
FI821466A7 (en) 1982-10-30
EP0063953A3 (en) 1983-10-19
PT74811A (en) 1982-05-01
PT74811B (en) 1983-10-26
ES511741A0 (en) 1983-06-01
JPS57181099A (en) 1982-11-08
BR8202422A (en) 1983-04-12
ZA822855B (en) 1983-03-30
DD203331A5 (en) 1983-10-19

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