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ES8302692A1 - Novel n-((2-oxo-1-pyrrolidinyl)acetyl)piperazine, manufacture of same and salts and medicine of therapeutical drug - Google Patents

Novel n-((2-oxo-1-pyrrolidinyl)acetyl)piperazine, manufacture of same and salts and medicine of therapeutical drug

Info

Publication number
ES8302692A1
ES8302692A1 ES510759A ES510759A ES8302692A1 ES 8302692 A1 ES8302692 A1 ES 8302692A1 ES 510759 A ES510759 A ES 510759A ES 510759 A ES510759 A ES 510759A ES 8302692 A1 ES8302692 A1 ES 8302692A1
Authority
ES
Spain
Prior art keywords
formula
oxo
acetyl
salts
pyrrolidinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES510759A
Other languages
Spanish (es)
Other versions
ES510759A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prodesfarma SA
Original Assignee
Prodes SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prodes SA filed Critical Prodes SA
Priority to ES510759A priority Critical patent/ES8302692A1/en
Publication of ES510759A0 publication Critical patent/ES510759A0/en
Publication of ES8302692A1 publication Critical patent/ES8302692A1/en
Priority to DE8383400607T priority patent/DE3361609D1/en
Priority to EP83400607A priority patent/EP0089900B1/en
Priority to AT83400607T priority patent/ATE17120T1/en
Priority to JP58049659A priority patent/JPS58174360A/en
Expired legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Procedure for the obtaining of n - [(2-oxo-1-pirrolidinil) acetyl] substituted piperazines and of their physiologically compatible salts, of formula (I), in which r can be one of various types of radicals and r " it is hydrogen, methyl or ethyl. It consists of the reaction of a mol of an amina of formula (II) with a mol or an excess of ester of formula (III) in which r "'' 'is methyle or ethyl; and r and r "have the same meaning as in formula (I). The reaction is carried out in a solid solvent or in absence of solvents, at temperatures comprised between 170ºc and 190ºc, eliminating the alcohol formed by distillation. (Machine-translation by Google Translate, not legally binding)
ES510759A 1982-03-24 1982-03-24 Novel n-((2-oxo-1-pyrrolidinyl)acetyl)piperazine, manufacture of same and salts and medicine of therapeutical drug Expired ES8302692A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ES510759A ES8302692A1 (en) 1982-03-24 1982-03-24 Novel n-((2-oxo-1-pyrrolidinyl)acetyl)piperazine, manufacture of same and salts and medicine of therapeutical drug
DE8383400607T DE3361609D1 (en) 1982-03-24 1983-03-23 New n-((2-oxo-1-pyrrolidinyl)acetyl)piperazines, the methods of producing such new compounds and their salts as well as pharmaceutical preparations for therapeutic use containing these compounds or salts
EP83400607A EP0089900B1 (en) 1982-03-24 1983-03-23 New n-((2-oxo-1-pyrrolidinyl)acetyl)piperazines, the methods of producing such new compounds and their salts as well as pharmaceutical preparations for therapeutic use containing these compounds or salts
AT83400607T ATE17120T1 (en) 1982-03-24 1983-03-23 N-((2-OXO-1-PYRROLIDINYL)ACETYL)PIPERAZINE, PROCESS FOR THEIR PRODUCTION AND THEIR SALTS AND THEIR USE IN PHARMACEUTICAL PREPARATIONS.
JP58049659A JPS58174360A (en) 1982-03-24 1983-03-24 Novel n-((2-oxo-1-pyrrolidinyl)acetyl)piperazine, manufacture of same and salts and medicine of therapeutical drug

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES510759A ES8302692A1 (en) 1982-03-24 1982-03-24 Novel n-((2-oxo-1-pyrrolidinyl)acetyl)piperazine, manufacture of same and salts and medicine of therapeutical drug

Publications (2)

Publication Number Publication Date
ES510759A0 ES510759A0 (en) 1983-02-01
ES8302692A1 true ES8302692A1 (en) 1983-02-01

Family

ID=8483886

Family Applications (1)

Application Number Title Priority Date Filing Date
ES510759A Expired ES8302692A1 (en) 1982-03-24 1982-03-24 Novel n-((2-oxo-1-pyrrolidinyl)acetyl)piperazine, manufacture of same and salts and medicine of therapeutical drug

Country Status (2)

Country Link
JP (1) JPS58174360A (en)
ES (1) ES8302692A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH075545B2 (en) * 1988-08-04 1995-01-25 明治製菓株式会社 Pyrrolidinone compound and cerebral dysfunction improving agent

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2278340A1 (en) * 1974-07-17 1976-02-13 Delalande Sa NEW DERIVATIVE OF N- (TRIMETHOXY-3,4,5 CINNAMOYL) PIPERAZINE, ITS ACID ADDITIONAL SALTS, ITS PREPARATION PROCESS AND ITS THERAPEUTIC APPLICATION

Also Published As

Publication number Publication date
ES510759A0 (en) 1983-02-01
JPS58174360A (en) 1983-10-13
JPS6344745B2 (en) 1988-09-06

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970612