ES8206544A1 - 4-carbamoyloxy-oxazaphosphorine compound - Google Patents
4-carbamoyloxy-oxazaphosphorine compoundInfo
- Publication number
- ES8206544A1 ES8206544A1 ES505324A ES505324A ES8206544A1 ES 8206544 A1 ES8206544 A1 ES 8206544A1 ES 505324 A ES505324 A ES 505324A ES 505324 A ES505324 A ES 505324A ES 8206544 A1 ES8206544 A1 ES 8206544A1
- Authority
- ES
- Spain
- Prior art keywords
- oxazaphosphorine
- carbamoyloxy
- compound
- carbamoyloxyoxazaphosphorines
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 4-carbamoyloxy-oxazaphosphorine compound Chemical class 0.000 title 1
- VZZWPFPWQGVAHK-UHFFFAOYSA-N 2h-oxazaphosphinin-4-yl carbamate Chemical class NC(=O)OC1=PNOC=C1 VZZWPFPWQGVAHK-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
- C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
The present invention relates to novel 4-carbamoyloxyoxazaphosphorines of the general formula I < IMAGE > to processes for their preparation, and to pharmaceutical preparations containing these active compounds.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8029222 | 1980-09-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES505324A0 ES505324A0 (en) | 1982-08-16 |
| ES8206544A1 true ES8206544A1 (en) | 1982-08-16 |
Family
ID=10515985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES505324A Expired ES8206544A1 (en) | 1980-09-10 | 1981-09-09 | 4-carbamoyloxy-oxazaphosphorine compound |
Country Status (29)
| Country | Link |
|---|---|
| JP (1) | JPS5785396A (en) |
| AR (1) | AR231989A1 (en) |
| AT (1) | AT386210B (en) |
| AU (1) | AU538275B2 (en) |
| BE (1) | BE890276A (en) |
| CA (2) | CA1161453A (en) |
| CH (1) | CH650787A5 (en) |
| CS (1) | CS227680B2 (en) |
| DD (1) | DD202166A5 (en) |
| DE (1) | DE3133309A1 (en) |
| DK (1) | DK400481A (en) |
| EG (1) | EG15392A (en) |
| ES (1) | ES8206544A1 (en) |
| FI (1) | FI70026C (en) |
| FR (1) | FR2489825A1 (en) |
| GR (1) | GR75300B (en) |
| HU (1) | HU185953B (en) |
| IE (1) | IE51784B1 (en) |
| IL (1) | IL63661A (en) |
| IT (2) | IT1198350B (en) |
| LU (1) | LU83613A1 (en) |
| NL (1) | NL8104093A (en) |
| NO (1) | NO161261C (en) |
| PL (1) | PL128627B1 (en) |
| PT (1) | PT73645B (en) |
| RO (1) | RO83972B (en) |
| SE (1) | SE458203B (en) |
| YU (1) | YU42584B (en) |
| ZA (1) | ZA815922B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA851062B (en) * | 1984-03-01 | 1985-11-27 | Asta Werke Ag Chem Fab | Salts of oxazaphosphorine derivatives and process for their production |
| DE3569737D1 (en) * | 1984-03-01 | 1989-06-01 | Asta Pharma Ag | Salts of oxazaphosphorine derivatives |
| WO2016089208A2 (en) | 2014-12-04 | 2016-06-09 | Stichting Maastricht Radiation Oncology "Maastro-Clinic" | Sulfonamide, sulfamate and sulfamide derivatives of anti-cancer agents |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA955937A (en) * | 1971-06-28 | 1974-10-08 | Shionogi And Co. Ltd. | Cyclic phosphamide derivatives |
| US3911005A (en) * | 1974-09-12 | 1975-10-07 | Monsanto Co | 1,3,2-Diazaphospholidine compounds |
| JPS5159886A (en) * | 1974-11-20 | 1976-05-25 | Shionogi Seiyaku Kk |
-
1981
- 1981-08-22 DE DE19813133309 patent/DE3133309A1/en active Granted
- 1981-08-25 IE IE1951/81A patent/IE51784B1/en unknown
- 1981-08-26 AU AU74657/81A patent/AU538275B2/en not_active Ceased
- 1981-08-26 ZA ZA815922A patent/ZA815922B/en unknown
- 1981-08-26 IL IL63661A patent/IL63661A/en not_active IP Right Cessation
- 1981-08-31 CH CH5584/81A patent/CH650787A5/en not_active IP Right Cessation
- 1981-08-31 GR GR65896A patent/GR75300B/el unknown
- 1981-09-03 NL NL8104093A patent/NL8104093A/en not_active Application Discontinuation
- 1981-09-04 CS CS816537A patent/CS227680B2/en unknown
- 1981-09-07 AT AT0386481A patent/AT386210B/en not_active IP Right Cessation
- 1981-09-07 LU LU83613A patent/LU83613A1/en unknown
- 1981-09-08 SE SE8105340A patent/SE458203B/en not_active IP Right Cessation
- 1981-09-08 FR FR8116999A patent/FR2489825A1/en active Granted
- 1981-09-08 RO RO105257A patent/RO83972B/en unknown
- 1981-09-08 HU HU812580A patent/HU185953B/en unknown
- 1981-09-08 DD DD81233132A patent/DD202166A5/en unknown
- 1981-09-08 EG EG508/81A patent/EG15392A/en active
- 1981-09-09 JP JP56141108A patent/JPS5785396A/en active Granted
- 1981-09-09 CA CA000385516A patent/CA1161453A/en not_active Expired
- 1981-09-09 NO NO813063A patent/NO161261C/en unknown
- 1981-09-09 ES ES505324A patent/ES8206544A1/en not_active Expired
- 1981-09-09 BE BE2/59345A patent/BE890276A/en not_active IP Right Cessation
- 1981-09-09 DK DK400481A patent/DK400481A/en not_active Application Discontinuation
- 1981-09-09 IT IT23860/81A patent/IT1198350B/en active
- 1981-09-09 PT PT73645A patent/PT73645B/en unknown
- 1981-09-09 FI FI812798A patent/FI70026C/en not_active IP Right Cessation
- 1981-09-09 PL PL1981232960A patent/PL128627B1/en unknown
- 1981-09-10 YU YU2179/81A patent/YU42584B/en unknown
- 1981-09-10 AR AR286736A patent/AR231989A1/en active
-
1984
- 1984-05-30 CA CA000455507A patent/CA1184563B/en not_active Expired
- 1984-06-12 IT IT21372/84A patent/IT1220985B/en active
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19971201 |