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ES8203016A1 - Un procedimiento para la preparacion de una solucion acuosa inyectable de sales de metales alcalinas de acido canrenoicoy de furosemida. - Google Patents

Un procedimiento para la preparacion de una solucion acuosa inyectable de sales de metales alcalinas de acido canrenoicoy de furosemida.

Info

Publication number
ES8203016A1
ES8203016A1 ES497657A ES497657A ES8203016A1 ES 8203016 A1 ES8203016 A1 ES 8203016A1 ES 497657 A ES497657 A ES 497657A ES 497657 A ES497657 A ES 497657A ES 8203016 A1 ES8203016 A1 ES 8203016A1
Authority
ES
Spain
Prior art keywords
furosemide
production
aqueous solutions
alkali salts
injectable aqueous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES497657A
Other languages
English (en)
Other versions
ES497657A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES497657A0 publication Critical patent/ES497657A0/es
Publication of ES8203016A1 publication Critical patent/ES8203016A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UNA SOLUCION ACUOSA INYECTABLE DE SALES DE METALES ALCALINOS DE ACIDO CANRENOICO Y DE FUROSEMIDA. CONSISTE EN SUSPENDER EN AGUA, A LA VEZ QUE SE EFECTUA UN TRATAMIENTO CON GAS INERTE, SALES DE METALES ALCALINOS DE ACIDO CANRENOICO Y DE FUROSEMIDA EN UNA PROPORCION DE 30:1 A 5:1, AJUSTANDO EL PH DE LA SUSPENSION ACUOSA FORMADA POR UN VALOR COMPRENDIDO ENTRE 10,2 Y 11,2, AL OBJETO DE OBTENER UNA SOLUCION TRANSPARENTE. MEDIANTE UN PROCESO DE ESTERILIZACION A 120 GRADOS SE ELIMINAN DE DICHA SOLUCION LOS GERMENES Y BACTERIAS, PROCEDIENDO A CONTINUACION A SU ENVASADO.
ES497657A 1979-12-18 1980-12-12 Un procedimiento para la preparacion de una solucion acuosa inyectable de sales de metales alcalinas de acido canrenoicoy de furosemida. Expired ES8203016A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2950832A DE2950832C2 (de) 1979-12-18 1979-12-18 Spritzfertige injizierbare wäßrige Lösungen der Alkalisalze von Canrenoinsäure und Furosemid

Publications (2)

Publication Number Publication Date
ES497657A0 ES497657A0 (es) 1982-02-16
ES8203016A1 true ES8203016A1 (es) 1982-02-16

Family

ID=6088769

Family Applications (1)

Application Number Title Priority Date Filing Date
ES497657A Expired ES8203016A1 (es) 1979-12-18 1980-12-12 Un procedimiento para la preparacion de una solucion acuosa inyectable de sales de metales alcalinas de acido canrenoicoy de furosemida.

Country Status (9)

Country Link
US (1) US4301160A (es)
EP (1) EP0030681B1 (es)
JP (1) JPS5697222A (es)
AT (1) ATE7852T1 (es)
AU (1) AU534886B2 (es)
CA (1) CA1154676A (es)
DE (2) DE2950832C2 (es)
ES (1) ES8203016A1 (es)
ZA (1) ZA807879B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3623620A1 (de) * 1986-07-12 1988-01-21 Boehringer Mannheim Gmbh Spritzfertige, waessrige, alkalische injektionsloesungen von torasemid und verfahren zu ihrer herstellung
US6892603B2 (en) * 2002-05-03 2005-05-17 Robert L. Barnett Rotatable control lever mount
CN103371967A (zh) * 2012-04-17 2013-10-30 上海禾丰制药有限公司 呋塞米注射液及其制剂工艺

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2216276B1 (es) * 1973-02-06 1976-11-05 Roussel Uclaf
DE2415258A1 (de) * 1974-03-29 1975-10-02 Boehringer Mannheim Gmbh Neuartige verwendung von aldadien und dessen derivaten
DE2423550A1 (de) * 1974-05-15 1975-11-27 Boehringer Mannheim Gmbh Pharmazeutisches praeparat
DE2556001C3 (de) * 1975-12-12 1979-11-29 Boehringer Mannheim Gmbh, 6800 Mannheim Spritzfertige injizierbare Lösungen mit einem Gehalt an Alkalicanrenoat

Also Published As

Publication number Publication date
DE2950832C2 (de) 1983-03-17
JPS5697222A (en) 1981-08-05
AU6545580A (en) 1981-06-25
ES497657A0 (es) 1982-02-16
DE3068259D1 (en) 1984-07-19
AU534886B2 (en) 1984-02-16
ATE7852T1 (de) 1984-06-15
DE2950832A1 (de) 1981-06-25
CA1154676A (en) 1983-10-04
EP0030681B1 (de) 1984-06-13
EP0030681A1 (de) 1981-06-24
US4301160A (en) 1981-11-17
ZA807879B (en) 1982-01-27

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