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ES8201962A1 - Un procedimiento para la preparacion de un compuesto de biu-ret 1,1,3,5-sustituido - Google Patents

Un procedimiento para la preparacion de un compuesto de biu-ret 1,1,3,5-sustituido

Info

Publication number
ES8201962A1
ES8201962A1 ES497342A ES497342A ES8201962A1 ES 8201962 A1 ES8201962 A1 ES 8201962A1 ES 497342 A ES497342 A ES 497342A ES 497342 A ES497342 A ES 497342A ES 8201962 A1 ES8201962 A1 ES 8201962A1
Authority
ES
Spain
Prior art keywords
formula
novel
pharmaceutical composition
same
composition containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES497342A
Other languages
English (en)
Other versions
ES497342A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiho Pharmaceutical Co Ltd
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Publication of ES8201962A1 publication Critical patent/ES8201962A1/es
Publication of ES497342A0 publication Critical patent/ES497342A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
    • C07C275/58—Y being a hetero atom
    • C07C275/62—Y being a nitrogen atom, e.g. biuret
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE UN COMPUESTO DE BIURET, 1,1,3,5-SUSTITUIDO DE FORMULA (I), DONDE R1 Y R2 SON UN GRUPO ALQUILO Y R3 CICLOHEXILO O FENILO. SE HACE REACCIONAR, A TEMPERATURA DE -20 A 50C., CLORURO DE ALOFANOILO DE FORMULA (II), DONDE W ES UN GRUPO DE FORMULA (III) U OTROS, CON UNA AMINA DE FORMULA (IV), SIENDO X HIDROGENO O EL RADICAL R1, Y X2 ES METILO O EL RADICAL. R3. LA REACCION PUEDE EFECTUARSE EN UN DISOLVENTE INERTE O EN PRESENCIA DE UN COMPUESTO BASICO TAL COMO TRIETILAMINA, PIRIDINA U OTROS, COMO AGENTES CONDENSANTES. LA RELACION MOLAR DE LOS REACTIVOS ES 2 MOLES DE AMINA/MOL DE CLORURO. EL PRODUCTO FINAL SE AISLA POR METODOS CONVENCIONALES.
ES497342A 1979-03-31 1980-12-01 Un procedimiento para la preparacion de un compuesto de biu-ret 1,1,3,5-sustituido Granted ES497342A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3879079A JPS55130952A (en) 1979-03-31 1979-03-31 1,1,3,5-substituted biuret compound

Publications (2)

Publication Number Publication Date
ES8201962A1 true ES8201962A1 (es) 1982-01-01
ES497342A0 ES497342A0 (es) 1982-01-01

Family

ID=12535093

Family Applications (2)

Application Number Title Priority Date Filing Date
ES490144A Granted ES490144A0 (es) 1979-03-31 1980-03-31 Un procedimiento para la preparacion de un compuesto de biu-ret 1,1,3,5-sustituido.
ES497342A Granted ES497342A0 (es) 1979-03-31 1980-12-01 Un procedimiento para la preparacion de un compuesto de biu-ret 1,1,3,5-sustituido

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES490144A Granted ES490144A0 (es) 1979-03-31 1980-03-31 Un procedimiento para la preparacion de un compuesto de biu-ret 1,1,3,5-sustituido.

Country Status (11)

Country Link
US (1) US4293713A (es)
JP (1) JPS55130952A (es)
AU (1) AU539805B2 (es)
CA (1) CA1126758A (es)
CH (1) CH645615A5 (es)
DE (1) DE3012124C2 (es)
ES (2) ES490144A0 (es)
FR (1) FR2453143A1 (es)
GB (1) GB2048856B (es)
IT (1) IT1143191B (es)
NL (1) NL184780C (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4278672A (en) * 1979-03-31 1981-07-14 Taiho Pharmaceutical Company, Limited Pharmaceutical composition and methods of use containing 1,1,3,5-substituted biuret compound
US4666911A (en) * 1981-07-14 1987-05-19 Taiho Pharmaceutical Company Limited Allophanoylpiperazine compound and analgesic composition containing same as active ingredient
US4668406A (en) * 1984-04-02 1987-05-26 Minnesota Mining And Manufacturing Company Fluorochemical biuret compositions and fibrous substrates treated therewith
GB8529797D0 (en) * 1985-12-03 1986-01-08 Shell Int Research Herbicides
SE529716C8 (sv) 2006-03-08 2007-12-04 Scan Coin Ind Ab Anordning och förfarande för kontantdeponering
SE531959C2 (sv) 2006-08-25 2009-09-15 Scan Coin Ind Ab En myntutmatningsanordning och en myntdeponerings- och utmatningsanordning

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL106227C (es) * 1956-12-21
US3149338A (en) * 1959-07-07 1964-09-15 Colgate Palmolive Co Hair preparations containing a diamide and process of use thereof
US3189431A (en) * 1960-09-15 1965-06-15 Du Pont Method for the control of undesirable plant growth
US3407193A (en) * 1965-03-09 1968-10-22 Horner Frank W Ltd Substituted biurets
GB1096005A (en) * 1965-03-09 1967-12-20 Horner Frank W Ltd Substituted biurets
US3556766A (en) * 1968-01-16 1971-01-19 Du Pont 1-arylbiurets as plant growth regulants

Also Published As

Publication number Publication date
AU5698380A (en) 1980-10-09
DE3012124A1 (de) 1980-10-02
CH645615A5 (de) 1984-10-15
AU539805B2 (en) 1984-10-18
GB2048856B (en) 1983-03-30
NL184780C (nl) 1989-11-01
FR2453143A1 (fr) 1980-10-31
GB2048856A (en) 1980-12-17
ES8104210A1 (es) 1981-04-16
ES490144A0 (es) 1981-04-16
US4293713A (en) 1981-10-06
JPS6223747B2 (es) 1987-05-25
CA1126758A (en) 1982-06-29
ES497342A0 (es) 1982-01-01
NL8001862A (nl) 1980-10-02
DE3012124C2 (de) 1982-04-08
JPS55130952A (en) 1980-10-11
NL184780B (nl) 1989-06-01
FR2453143B1 (es) 1984-02-10
IT8048283A0 (it) 1980-03-28
IT1143191B (it) 1986-10-22

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971001