ES8106907A1 - Procedimiento para la preparacion de soluciones de acidos 7-aminocefalosporanicos - Google Patents
Procedimiento para la preparacion de soluciones de acidos 7-aminocefalosporanicosInfo
- Publication number
- ES8106907A1 ES8106907A1 ES497076A ES497076A ES8106907A1 ES 8106907 A1 ES8106907 A1 ES 8106907A1 ES 497076 A ES497076 A ES 497076A ES 497076 A ES497076 A ES 497076A ES 8106907 A1 ES8106907 A1 ES 8106907A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- aminocephalosporanic acid
- preparation
- manufacture
- acid solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 abstract 2
- -1 ACETOXYMETHYL Chemical class 0.000 abstract 1
- 229930186147 Cephalosporin Natural products 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 229940124587 cephalosporin Drugs 0.000 abstract 1
- HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 239000012467 final product Substances 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000013067 intermediate product Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical class [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
Landscapes
- Cephalosporin Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PROCEDIMIENTO DE PREPARACION DE SOLUCIONES DE ACIDOS 7-AMINOCEFALOSPORANICOS. SE SUSPENDE EN UN SOLVENTE ORGANICO UN COMPUESTO DE FORMULA (I), DONDE R1 ES HIDROGENO O ALCOHOXI DE BAJO PESO MOLECULAR Y R2 METILO, ACETOXIMETILO, METOXI, CLORO O UN GRUPO TIOL-HETEROCICLICO. SE ADICIONA GRADUALMENTE UNA AMIDINA-BICICLICA DE FORMULA (II) HASTA ALCANZAR LA DISOLUCION. SE ENFRIA LA MEZCLA Y SE FILTRA. SE AÑADE UN REACTIVO ACILANTE PARA AJUSTAR EL PH. SE AISLA EL PRODUCTO FINAL POR FILTRACION Y SECADO. SE USAN EN LA ELABORACION DE CEFALOSPORINAS ANTIBIOTICAS, COMO PRODUCTOS INTERMEDIOS. *FORMULA*
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES497076A ES497076A0 (es) | 1980-11-22 | 1980-11-22 | Procedimiento para la preparacion de soluciones de acidos 7-aminocefalosporanicos |
| DK508881A DK165118C (da) | 1980-11-22 | 1981-11-17 | Fremgangsmaade til fremstilling af oploesninger af 7-aminocephalosporansyrer |
| US06/323,403 US4405782A (en) | 1980-11-22 | 1981-11-20 | Process for the preparation of solutions of 7-aminocephalosporanic acids |
| AT81401848T ATE20068T1 (de) | 1980-11-22 | 1981-11-20 | Salze von 7-amino-cephalosporinsaeure, loeslich in organischen loesungsmittel, und ihre verwendung fuer die herstellung von cephalosporinverbindungen. |
| DE8181401848T DE3174735D1 (en) | 1980-11-22 | 1981-11-20 | Salts of 7-aminocephalosporanic acids, soluble in organic solvents and their use in the preparation of cephalosporins |
| EP81401848A EP0053077B1 (en) | 1980-11-22 | 1981-11-20 | Salts of 7-aminocephalosporanic acids, soluble in organic solvents and their use in the preparation of cephalosporins |
| JP56186149A JPS57116083A (en) | 1980-11-22 | 1981-11-21 | Manufacture of 7-aminocephalosporanic acid solution |
| CA000390705A CA1173824A (en) | 1980-11-22 | 1981-11-23 | Process for the preparation of solutions of 7- aminocephalosporanic acids |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES497076A ES497076A0 (es) | 1980-11-22 | 1980-11-22 | Procedimiento para la preparacion de soluciones de acidos 7-aminocefalosporanicos |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8106907A1 true ES8106907A1 (es) | 1981-10-01 |
| ES497076A0 ES497076A0 (es) | 1981-10-01 |
Family
ID=8481426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES497076A Granted ES497076A0 (es) | 1980-11-22 | 1980-11-22 | Procedimiento para la preparacion de soluciones de acidos 7-aminocefalosporanicos |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JPS57116083A (es) |
| ES (1) | ES497076A0 (es) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2758000A1 (de) * | 1977-12-24 | 1979-07-05 | Hoechst Ag | Verfahren zur herstellung von penicillinen und cephalosporinen |
-
1980
- 1980-11-22 ES ES497076A patent/ES497076A0/es active Granted
-
1981
- 1981-11-21 JP JP56186149A patent/JPS57116083A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0322391B2 (es) | 1991-03-26 |
| JPS57116083A (en) | 1982-07-19 |
| ES497076A0 (es) | 1981-10-01 |
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