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ES8104790A1 - Procedimiento para la preparacion de derivados de la glici- namida - Google Patents

Procedimiento para la preparacion de derivados de la glici- namida

Info

Publication number
ES8104790A1
ES8104790A1 ES490536A ES490536A ES8104790A1 ES 8104790 A1 ES8104790 A1 ES 8104790A1 ES 490536 A ES490536 A ES 490536A ES 490536 A ES490536 A ES 490536A ES 8104790 A1 ES8104790 A1 ES 8104790A1
Authority
ES
Spain
Prior art keywords
group
linear
ramified
represents hydrogen
alkyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES490536A
Other languages
English (en)
Other versions
ES490536A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Continental Pharma Inc
Original Assignee
Continental Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from LU81069A external-priority patent/LU81069A1/fr
Priority claimed from LU81068A external-priority patent/LU81068A1/fr
Application filed by Continental Pharma Inc filed Critical Continental Pharma Inc
Publication of ES490536A0 publication Critical patent/ES490536A0/es
Publication of ES8104790A1 publication Critical patent/ES8104790A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE LA GLICINAMIDA DE FORMULA GENERAL (I). CONSISTENTE EN PREPARAR DERIVADOS DE (I), LO CUAL PUEDE CONSEGUIRSE POR DIVERSOS PROCEDIMIENTOS. ENTRE LOS METODOS DE PREPARACION PUEDE UTILIZARSE EL QUE SE PARTE DE LA AMINA DE FORMULA (II). TAMBIEN PUEDEN UTILIZARSE METODOS ALTERNATIVOS DE PREPARACION, TALES COMO POR HIDROGENOLOSIS CATALITICA DE UNA SIGNONIMINIA, O POR REACCION DE UN ALDEHIDO O AMINA CON UN ISONITRILO EN PRESENCIA DE UN ACIDO CARBOXILICO. SE TRATA DE OBTENER COMO RESULTADO FINAL COMPOSICIONES QUE CONTIENEN COMO PRINCIPIO ACTIVO, AL MENOS, UN COMPUESTO (I) Y/O UNA SAL DEL MISMO. DE APLICACION EN EL TRATAMIENTO DE DIVERSAS FORMAS DE EPILEPSIA, DISQUINESIAS, TRASTORNOS DE LA MEMORIA Y TRASTORNOS PSIQUICOS COMO LA DEPRESION. *FORMULA* C
ES490536A 1979-03-22 1980-03-21 Procedimiento para la preparacion de derivados de la glici- namida Expired ES8104790A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU81069A LU81069A1 (fr) 1979-03-22 1979-03-22 Derive de glycinamide, preparation de ce derive, son utilisation ainsi que composition contenant ce derive
LU81068A LU81068A1 (fr) 1979-03-22 1979-03-22 Derives de la glycinamide, leur preparation et utilisation, ainsi que compositions contenant ces derives

Publications (2)

Publication Number Publication Date
ES490536A0 ES490536A0 (es) 1981-04-16
ES8104790A1 true ES8104790A1 (es) 1981-04-16

Family

ID=26640253

Family Applications (1)

Application Number Title Priority Date Filing Date
ES490536A Expired ES8104790A1 (es) 1979-03-22 1980-03-21 Procedimiento para la preparacion de derivados de la glici- namida

Country Status (18)

Country Link
US (1) US4639468A (es)
AT (1) AT381302B (es)
AU (1) AU536499B2 (es)
CA (1) CA1184567A (es)
CH (1) CH645091A5 (es)
DE (2) DE3010599A1 (es)
DK (1) DK162714C (es)
ES (1) ES8104790A1 (es)
FI (1) FI82033C (es)
FR (1) FR2451913A1 (es)
GB (1) GB2048852B (es)
GR (1) GR68005B (es)
IE (1) IE49751B1 (es)
IL (1) IL59679A (es)
NL (1) NL191508C (es)
NO (1) NO157817C (es)
PT (1) PT70992A (es)
SE (1) SE453917B (es)

Families Citing this family (54)

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DE2937698A1 (de) * 1979-09-18 1981-04-02 A. Nattermann & Cie GmbH, 5000 Köln N-propionylsarcosinanilide, deren herstellungsverfahren und arzneimittel auf deren basis
FI832935A7 (fi) * 1982-08-20 1984-02-21 Midit Derivat av w-aminosyror, deras framstaellning samt dessa derivat innehaollande blandningar
US4798687A (en) * 1987-02-06 1989-01-17 Pennwalt Corporation 2-Amino-N-[1,2-Diphenyl-1-(thifluoromethyl)ethyl]acetamide derivatives
US4904681A (en) * 1987-12-01 1990-02-27 G. D. Searle & Co. D-cycloserine and its prodrugs as cognitive enhancers
US4891058A (en) * 1988-07-18 1990-01-02 Ici Americas Inc. 1-alkyl-3-aryl imidazolidine-2,4-diones and herbicidal use
US5278191A (en) * 1988-08-31 1994-01-11 G. D. Searle & Co. Diphenylmethylaminoacetamide derivatives as anti-convulsants
US5288905A (en) * 1988-10-07 1994-02-22 G. D. Searle & Co. Glycyl urea derivatives as anti-convulsants
US4944796A (en) * 1988-11-14 1990-07-31 Ici Americas Inc. Certain 2-(disubstituted amino) acetanilide herbicides
DE3915755A1 (de) * 1989-05-13 1990-11-29 Bayer Ag Fungizide mittel sowie substituierte aminosaeureamid-derivate und deren herstellung
IL94466A (en) * 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation
US5075337A (en) * 1989-07-26 1991-12-24 G. D. Searle & Co. Alpha-deuterated 2-alkylaminoacetamide derivatives having reduced toxicity for treatment of CNS disorders
US5153226A (en) * 1989-08-31 1992-10-06 Warner-Lambert Company Acat inhibitors for treating hypocholesterolemia
DE4102042A1 (de) * 1991-01-24 1992-07-30 Bayer Ag Substituierte aminosaeureamid-derivate deren herstellung und verwendung als fungizide
US5141960A (en) * 1991-06-25 1992-08-25 G. D. Searle & Co. Tricyclic glycinamide derivatives as anti-convulsants
GB9306899D0 (en) * 1993-04-01 1993-05-26 Erba Carlo Spa Substituted (arylalkylaminobenzyl) aminopropionamide derivatives and process for their preparation
GB9306886D0 (en) * 1993-04-01 1993-05-26 Erba Carlo Spa Substituted (arylakoxybenzyl) aminopropanamide derivatives and process for their preparation
US5585358A (en) * 1993-07-06 1996-12-17 Yissum Research Development Corporation Of The Hebrew University Of Jerusalem Derivatives of valproic acid amides and 2-valproenoic acid amides, method of making and use thereof as anticonvulsant agents
NZ332780A (en) * 1996-05-31 2000-07-28 Allelix Neuroscience Inc Substituted amines for the treatment of neurological and neuropsychiatric disorders
US6191165B1 (en) * 1996-05-31 2001-02-20 Allelix Neuroscience Inc. Pharmaceutical for treatment of neurological and neuropsychiatric disorders
IT1283489B1 (it) * 1996-07-23 1998-04-21 Chiesi Farma Spa Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
BR9909103A (pt) * 1998-03-26 2001-10-16 Univ Saskatchewan ácidos alifático amino carboxìlico e amino fosfÈnico, amino nitrilas e amino tetrazóis como agentes de resgate celular
US6984754B1 (en) 1998-03-26 2006-01-10 University Of Saskatchewan Technologies Inc. Aliphatic amino carboxylic and amino phosphonic acids amino nitriles and amino tetrazoles as cellular rescue agents
WO2000046183A1 (en) * 1999-02-08 2000-08-10 Checkpoint Genetics, Inc. N-substituted amino acids, antioxidant pharmaceutical compositions containing same and methods using same
CN1251758C (zh) * 2000-07-21 2006-04-19 特瓦制药工业有限公司 丙戊酸和2－丙基戊烯酸酰胺的衍生物在制备治疗双极情感障碍症躁狂病药物中的用途
JP2004505999A (ja) * 2000-08-17 2004-02-26 テバ　ファーマシューティカル　インダストリーズ　リミティド 疼痛および／または頭痛疾患の治療または予防のための、バルプロ酸アミドおよび２−バルプロエン酸アミドの誘導体の使用
EP1339669B1 (en) * 2000-11-21 2008-06-04 UCB Pharma, S.A. N-alkylated gaba compounds, processes for their preparation and their use as medicaments
CZ20032503A3 (cs) 2001-02-16 2004-02-18 Allelix Neuroscience, Inc. Inhibitory GlyT - 1
US20030035784A1 (en) * 2001-03-05 2003-02-20 Kao Corporation Hair cosmetic, aminocarboxylic acid amide and method for producing the same
ATE317280T1 (de) 2001-09-03 2006-02-15 Newron Pharm Spa Pharmazeutische zusammensetzung mit gabapentin oder deren analog und einem alpha-aminoamid und analgetische verwendung dieser zusammensetzung
EP1438956A1 (en) * 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
KR101277520B1 (ko) * 2004-09-10 2013-06-21 뉴론 파마슈티칼즈 에스. 피. 에이. （할로벤질옥시）벤질아미노－프로판아미드를 포함하는 선택적 나트륨 및／또는 칼슘 채널 조절제로서 유용한 약제학적 조성물
JP4995086B2 (ja) * 2004-09-13 2012-08-08 チバ ホールディング インコーポレーテッド アルキルアミノアセトアミド潤滑油添加剤
FR2896991A1 (fr) * 2006-02-03 2007-08-10 Inst Nat Sante Rech Med Procede pour preparer un compose organique a l'etat solide et compositions pharmaceutiques comprenant ledit compose organique
CN102351733B (zh) * 2011-07-21 2014-03-19 凯莱英医药化学（阜新）技术有限公司 一种制备2-氨基-n,n-二甲基乙酰胺盐酸盐的方法
IL298516B2 (en) 2014-06-25 2025-03-01 Acuitas Therapeutics Inc Novel lipids and lipid nanoparticle compositions for nucleic acid delivery
JP6053724B2 (ja) * 2014-06-26 2016-12-27 国立大学法人九州大学 イオン交換樹脂及び金属の吸着分離方法
SI3313829T1 (sl) 2015-06-29 2024-09-30 Acuitas Therapeutics Inc. Lipidi in formulacije lipidnih nanodelcev za dostavo nukleinskih kislin
RS63986B1 (sr) 2015-10-28 2023-03-31 Acuitas Therapeutics Inc Novi lipidi i lipidne formulacije nanočestica za isporuku nukleinskih kiselina
CN106187829B (zh) * 2016-07-29 2017-12-15 万华化学集团股份有限公司 一种制备乙二胺基乙磺酸盐的方法
US12491261B2 (en) 2016-10-26 2025-12-09 Acuitas Therapeutics, Inc. Lipid nanoparticle formulations
WO2018191657A1 (en) 2017-04-13 2018-10-18 Acuitas Therapeutics, Inc. Lipids for delivery of active agents
ES2981244T3 (es) 2017-04-28 2024-10-07 Acuitas Therapeutics Inc Novedosas formulaciones de nanopartículas de lípidos de carbonilo y lípidos para la administración de ácidos nucleicos
JP7355731B2 (ja) 2017-08-16 2023-10-03 アクイタス セラピューティクス インコーポレイテッド 脂質ナノ粒子製剤における使用のための脂質
US12065396B2 (en) 2017-08-17 2024-08-20 Acuitas Therapeutics, Inc. Lipids for use in lipid nanoparticle formulations
WO2019036028A1 (en) 2017-08-17 2019-02-21 Acuitas Therapeutics, Inc. LIPIDS FOR USE IN LIPID NANOPARTICULAR FORMULATIONS
US11524932B2 (en) 2017-08-17 2022-12-13 Acuitas Therapeutics, Inc. Lipids for use in lipid nanoparticle formulations
IL281615B1 (en) 2018-09-21 2025-09-01 Acuitas Therapeutics Inc Systems and methods for producing lipid nanoparticles and liposomes
KR101953366B1 (ko) 2018-12-26 2019-02-28 정종문 침향을 포함하는 기억력 및 인지능력을 향상시키는 기능성 건강식품 및 이의 제조방법
AU2020205717B2 (en) 2019-01-11 2025-09-11 Acuitas Therapeutics, Inc. Lipids for lipid nanoparticle delivery of active agents
USD926577S1 (en) 2019-09-23 2021-08-03 Verdant Ventures Tamper-resistant lid assembly
US11326923B2 (en) 2019-10-08 2022-05-10 Verdant Ventures Tamper-resistant lid assembly for dispensing a premeasured amount of liquid
CA3189338A1 (en) 2020-07-16 2022-01-20 Acuitas Therapeutics, Inc. Cationic lipids for use in lipid nanoparticles
WO2023114943A2 (en) 2021-12-16 2023-06-22 Acuitas Therapeutics, Inc. Lipids for use in lipid nanoparticle formulations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2368208A (en) * 1940-12-16 1945-01-30 Emulsol Corp Chemical compounds and method of preparing same
US2781385A (en) * 1953-09-21 1957-02-12 Gefgy Chemical Corp Diamidocarboxylic acids and certain salts thereof
LU43649A1 (es) * 1962-05-09 1963-07-16
JPS5319654B2 (es) 1974-03-14 1978-06-22
DE2832009A1 (de) 1978-07-20 1980-01-31 Deutsches Krebsforsch Verwendung von sarkosin und sarkosinderivaten ls tumorhemmende wirksubstanzen

Also Published As

Publication number Publication date
NO157817C (no) 1988-05-25
DE3010599A1 (de) 1980-10-09
GR68005B (es) 1981-10-26
DE3010599C2 (es) 1989-03-02
CA1184567A (en) 1985-03-26
CH645091A5 (fr) 1984-09-14
FI82033C (fi) 1991-01-10
NO800830L (no) 1980-09-23
PT70992A (fr) 1980-04-01
FI800900A7 (fi) 1980-09-23
DK123580A (da) 1980-09-23
SE453917B (sv) 1988-03-14
IL59679A0 (en) 1980-06-30
ES490536A0 (es) 1981-04-16
AU5678480A (en) 1980-09-25
FI82033B (fi) 1990-09-28
NL8001721A (nl) 1980-09-24
NL191508B (nl) 1995-04-18
DE3050800C2 (es) 1989-06-22
AU536499B2 (en) 1984-05-10
IE49751B1 (en) 1985-12-11
DK162714C (da) 1992-04-21
AT381302B (de) 1986-09-25
DK162714B (da) 1991-12-02
IE800599L (en) 1980-09-22
GB2048852A (en) 1980-12-17
ATA154680A (de) 1986-02-15
FR2451913A1 (fr) 1980-10-17
FR2451913B1 (es) 1984-07-13
GB2048852B (en) 1983-03-30
SE8002204L (sv) 1980-09-23
NO157817B (no) 1988-02-15
NL191508C (nl) 1995-08-21
IL59679A (en) 1984-11-30
US4639468A (en) 1987-01-27

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