ES479798A1 - Procedure for the obtaining of phthalide ester of acid 6 (dc -) - a - aminofenilacetamido) penicilanico and its organic or inorganic salts. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the obtaining of phthalide ester of acid 6 (dc -) - a - aminofenilacetamido) penicilanico and its organic or inorganic salts. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES479798A1 ES479798A1 ES479798A ES479798A ES479798A1 ES 479798 A1 ES479798 A1 ES 479798A1 ES 479798 A ES479798 A ES 479798A ES 479798 A ES479798 A ES 479798A ES 479798 A1 ES479798 A1 ES 479798A1
- Authority
- ES
- Spain
- Prior art keywords
- organic
- acid
- penicilanico
- aminofenilacetamido
- translation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- WNZQDUSMALZDQF-UHFFFAOYSA-N isobenzofuranone Natural products C1=CC=C2C(=O)OCC2=C1 WNZQDUSMALZDQF-UHFFFAOYSA-N 0.000 title abstract 4
- 239000002253 acid Substances 0.000 title abstract 3
- -1 phthalide ester Chemical class 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 abstract 1
- 230000008020 evaporation Effects 0.000 abstract 1
- 150000007529 inorganic bases Chemical class 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 238000006386 neutralization reaction Methods 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- RBKMMJSQKNKNEV-RITPCOANSA-N penicillanic acid Chemical compound OC(=O)[C@H]1C(C)(C)S[C@@H]2CC(=O)N21 RBKMMJSQKNKNEV-RITPCOANSA-N 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Landscapes
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedure for the obtaining of the phthalide ester of the acid 6 (d (-) - alpha-aminofenilacetamido) penicilanico and its organic or inorganic salts.- characterized in that it consists of reacting in organic or aqueous-organic medium the sodium salt of the acid 6 ( N-methylene-d (-) - alpha-amino phenyl acetamido) penicillanic acid with a 3-sulfonate of phthalide at temperatures between -10 and 40ºC isolating the product obtained by evaporation of the solvent or precipitation and subsequent acid hydrolysis with organic or inorganic acids to obtain the salts of the ester with subsequent neutralization with organic or inorganic bases to obtain the ester according to the following reaction scheme: ** (formula-01) ** ** (formula-02) ** ** (formula-03) ** ** (formula-04) ** (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES479798A ES479798A1 (en) | 1979-04-20 | 1979-04-20 | Procedure for the obtaining of phthalide ester of acid 6 (dc -) - a - aminofenilacetamido) penicilanico and its organic or inorganic salts. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES479798A ES479798A1 (en) | 1979-04-20 | 1979-04-20 | Procedure for the obtaining of phthalide ester of acid 6 (dc -) - a - aminofenilacetamido) penicilanico and its organic or inorganic salts. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES479798A1 true ES479798A1 (en) | 1979-12-01 |
Family
ID=8478113
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES479798A Expired ES479798A1 (en) | 1979-04-20 | 1979-04-20 | Procedure for the obtaining of phthalide ester of acid 6 (dc -) - a - aminofenilacetamido) penicilanico and its organic or inorganic salts. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES479798A1 (en) |
-
1979
- 1979-04-20 ES ES479798A patent/ES479798A1/en not_active Expired
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970519 |