ES459401A1 - 6,11-dihydrodibenzo - thiepin - 11 - ones methods of preparation compositions and uses thereof - Google Patents
6,11-dihydrodibenzo - thiepin - 11 - ones methods of preparation compositions and uses thereofInfo
- Publication number
- ES459401A1 ES459401A1 ES459401A ES459401A ES459401A1 ES 459401 A1 ES459401 A1 ES 459401A1 ES 459401 A ES459401 A ES 459401A ES 459401 A ES459401 A ES 459401A ES 459401 A1 ES459401 A1 ES 459401A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- salt
- dihydrodibenzo
- pharmaceutically acceptable
- thiepin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D337/12—[b,e]-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
A process for the production of new 6, 11-dihydrodibenzo [be] tiepin-11-one compounds of general formula ** formula ** wherein R'' is hydrogen or methyl, independently including the (dl), (d) isomers, and (l) where R'' is methyl, and R is an alkyl group having 1 to 12 carbon atoms, or a pharmaceutically acceptable salt residue, characterized in that process by reacting an acid of formula ** formula ** where R'' is as defined above, with a reactive alcohol or a pharmaceutically acceptable base to obtain the corresponding pharmaceutically acceptable ester or salt of formula (I) and optionally converting the salt thus obtained to another salt (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55031675A | 1975-02-18 | 1975-02-18 | |
| US59172575A | 1975-06-30 | 1975-06-30 | |
| US05/634,086 US4000308A (en) | 1975-02-18 | 1975-11-21 | 6,11-Dihydrodibenzo-thiepin-11-ones, compositions and uses thereof |
| US05/634,085 US4000288A (en) | 1975-02-18 | 1975-11-21 | 6,11-dihydrodibenzo-thiepin-11-ones, compositions and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES459401A1 true ES459401A1 (en) | 1979-06-16 |
Family
ID=27504746
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES459400A Expired ES459400A1 (en) | 1975-02-18 | 1977-06-01 | 6,11-dihydrodibenzo - thiepin - 11 - ones methods of preparation compositions and uses thereof |
| ES459401A Expired ES459401A1 (en) | 1975-02-18 | 1977-06-01 | 6,11-dihydrodibenzo - thiepin - 11 - ones methods of preparation compositions and uses thereof |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES459400A Expired ES459400A1 (en) | 1975-02-18 | 1977-06-01 | 6,11-dihydrodibenzo - thiepin - 11 - ones methods of preparation compositions and uses thereof |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS51143688A (en) |
| AR (1) | AR216050A1 (en) |
| AT (1) | AT352731B (en) |
| AU (1) | AU500501B2 (en) |
| BE (1) | BE838637A (en) |
| DE (1) | DE2606312A1 (en) |
| DK (1) | DK67676A (en) |
| ES (2) | ES459400A1 (en) |
| FI (1) | FI760273A7 (en) |
| FR (1) | FR2301245A1 (en) |
| GB (1) | GB1505085A (en) |
| IL (1) | IL48807A0 (en) |
| NL (1) | NL7600899A (en) |
| NO (1) | NO760297L (en) |
| PT (1) | PT64692B (en) |
| SE (1) | SE7601754L (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4130654A (en) * | 1978-01-30 | 1978-12-19 | Syntex (U.S.A.) Inc. | Novel 4-(8X-6,11-dihydrodibenzo-[b.e.]-thiepin-11-one-3-yl)-4-oxobutyric acids, methods of preparation, compositions and uses thereof |
| TW200615273A (en) * | 2004-11-10 | 2006-05-16 | Nicholas Piramal India Ltd | Fused tricyclic compounds as inhibitors of tumor necrosis factor-alpha |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK467274A (en) * | 1973-09-13 | 1975-05-12 | Sandoz Ag |
-
1976
- 1976-01-08 IL IL48807A patent/IL48807A0/en unknown
- 1976-01-14 PT PT64692A patent/PT64692B/en unknown
- 1976-01-16 GB GB1783/76A patent/GB1505085A/en not_active Expired
- 1976-01-29 NL NL7600899A patent/NL7600899A/en not_active Application Discontinuation
- 1976-01-30 AU AU10686/76A patent/AU500501B2/en not_active Expired
- 1976-01-30 NO NO760297A patent/NO760297L/no unknown
- 1976-02-04 AR AR262140A patent/AR216050A1/en active
- 1976-02-05 FI FI760273A patent/FI760273A7/fi not_active Application Discontinuation
- 1976-02-17 DE DE19762606312 patent/DE2606312A1/en active Pending
- 1976-02-17 BE BE164382A patent/BE838637A/en unknown
- 1976-02-17 JP JP51016446A patent/JPS51143688A/en active Pending
- 1976-02-17 SE SE7601754A patent/SE7601754L/en unknown
- 1976-02-17 FR FR7604353A patent/FR2301245A1/en active Granted
- 1976-02-18 AT AT115976A patent/AT352731B/en not_active IP Right Cessation
- 1976-02-18 DK DK67676*#A patent/DK67676A/en unknown
-
1977
- 1977-06-01 ES ES459400A patent/ES459400A1/en not_active Expired
- 1977-06-01 ES ES459401A patent/ES459401A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU1068676A (en) | 1977-08-04 |
| GB1505085A (en) | 1978-03-22 |
| NL7600899A (en) | 1976-08-20 |
| DE2606312A1 (en) | 1976-08-26 |
| AU500501B2 (en) | 1979-05-24 |
| FR2301245B1 (en) | 1979-07-20 |
| ES459400A1 (en) | 1978-08-16 |
| NO760297L (en) | 1976-08-19 |
| PT64692B (en) | 1978-01-04 |
| FI760273A7 (en) | 1976-08-19 |
| DK67676A (en) | 1976-08-19 |
| SE7601754L (en) | 1976-10-25 |
| ATA115976A (en) | 1979-03-15 |
| FR2301245A1 (en) | 1976-09-17 |
| PT64692A (en) | 1976-02-01 |
| AT352731B (en) | 1979-10-10 |
| AR216050A1 (en) | 1979-11-30 |
| IL48807A0 (en) | 1976-03-31 |
| JPS51143688A (en) | 1976-12-10 |
| BE838637A (en) | 1976-08-17 |
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