ES454086A1 - Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-norosimorfona nuevas. - Google Patents

Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-norosimorfona nuevas.

Info

Publication number: ES454086A1
Authority: ES; Spain
Prior art keywords: tetrahydrofurfuril; new; translation; procedure; preparation
Prior art date: 1975-08-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES454086A

Other languages

English (en)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

CH Boehringer Sohn AG and Co KG

Original Assignee

CH Boehringer Sohn AG and Co KG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-08-27

Filing date

1976-12-09

Publication date

1977-11-16

1976-12-09 Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG

1977-11-16 Publication of ES454086A1 publication Critical patent/ES454086A1/es

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
- C07D489/08—Oxygen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Saccharide Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

ES454086A 1975-08-27 1976-12-09 Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-norosimorfona nuevas. Expired ES454086A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19752538075 DE2538075A1 (de)	1975-08-27	1975-08-27	N-tetrahydrofurfuryl-noroxymorphone, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung

Publications (1)

Publication Number	Publication Date
ES454086A1 true ES454086A1 (es)	1977-11-16

Family

ID=5954931

Family Applications (5)

Application Number	Title	Priority Date	Filing Date
ES450897A Expired ES450897A1 (es)	1975-08-27	1976-08-21	Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona.
ES454085A Expired ES454085A1 (es)	1975-08-27	1976-12-09	Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona nuevas.
ES454087A Expired ES454087A2 (es)	1975-08-27	1976-12-09	Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona nuevas.
ES454084A Expired ES454084A1 (es)	1975-08-27	1976-12-09	Procedimiento para la preparmacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona nuevas.
ES454086A Expired ES454086A1 (es)	1975-08-27	1976-12-09	Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-norosimorfona nuevas.

Family Applications Before (4)

Application Number	Title	Priority Date	Filing Date
ES450897A Expired ES450897A1 (es)	1975-08-27	1976-08-21	Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona.
ES454085A Expired ES454085A1 (es)	1975-08-27	1976-12-09	Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona nuevas.
ES454087A Expired ES454087A2 (es)	1975-08-27	1976-12-09	Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona nuevas.
ES454084A Expired ES454084A1 (es)	1975-08-27	1976-12-09	Procedimiento para la preparmacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona nuevas.

Country Status (33)

Country	Link
US (1)	US4100288A (es)
JP (1)	JPS5231100A (es)
AT (1)	AT350737B (es)
AU (1)	AU499926B2 (es)
BE (1)	BE845563A (es)
BG (2)	BG27546A4 (es)
CA (1)	CA1068266A (es)
CH (5)	CH622521A5 (es)
CS (2)	CS192564B2 (es)
DD (1)	DD127145A5 (es)
DE (1)	DE2538075A1 (es)
DK (1)	DK143278C (es)
ES (5)	ES450897A1 (es)
FI (1)	FI762430A7 (es)
FR (1)	FR2321888A1 (es)
GB (1)	GB1519719A (es)
GR (1)	GR61158B (es)
HU (1)	HU176929B (es)
IE (1)	IE44069B1 (es)
IL (1)	IL50355A (es)
LU (1)	LU75667A1 (es)
MX (1)	MX4133E (es)
NL (1)	NL7609485A (es)
NO (1)	NO145793C (es)
NZ (1)	NZ181864A (es)
PH (1)	PH13780A (es)
PL (2)	PL109091B1 (es)
PT (1)	PT65521B (es)
RO (1)	RO69457A (es)
SE (1)	SE7609495L (es)
SU (2)	SU612631A3 (es)
YU (1)	YU208176A (es)
ZA (1)	ZA765120B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4272541A (en) *	1978-06-02	1981-06-09	Miles Laboratories, Inc.	7,8 and 7-8 Substituted 4,5α-epoxymorphinan-6-one compounds, and methods of treating pain and drug dependence with them
US4272540A (en) *	1979-04-24	1981-06-09	Sisa, Incorporated	14-Methoxymorphinan-6-one compounds and therapeutic methods of treating pain and drug dependence with them
DE3220831A1 (de) *	1982-06-03	1983-12-08	Boehringer Ingelheim KG, 6507 Ingelheim	N-(2-methoxyethyl)-noroxymorphon, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
CN101466381B (zh) *	2006-04-21	2012-11-14	尼克塔治疗公司	吗啡酮的立体选择性还原
ES2708726T3 (es) *	2010-07-08	2019-04-10	Alkermes Pharma Ireland Ltd	Proceso para la síntesis de morfinanos sustituidos
US9211293B2 (en)	2011-12-15	2015-12-15	Alkermes Pharma Ireland Limited	Opioid agonist antagonist combinations
EP3003311A2 (en)	2013-05-24	2016-04-13	Alkermes Pharma Ireland Limited	Methods for treating depressive symptoms
JP2016519161A (ja)	2013-05-24	2016-06-30	アルカームスファーマアイルランドリミテッド	モルファン及びモルフィナン類似物及び使用の方法
WO2019165298A1 (en) *	2018-02-23	2019-08-29	Rhodes Technologies	Novel opioid compounds and uses thereof
EP4243768A1 (en)	2020-11-12	2023-09-20	Alkermes Pharma Ireland Limited	Immediate release multilayer tablet

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH446370A (de)	1964-03-05	1967-11-15	Hoffmann La Roche	Verfahren zur Herstellung von Phenanthren-Derivaten
DE2238839A1 (de) *	1972-08-07	1974-02-14	Boehringer Sohn Ingelheim	Neue morphinon-derivate, deren saeureadditionssalze, verfahren zu ihrer herstellung sowie ihre verwendung zur herstellung von arzneimitteln

1975
- 1975-08-27 DE DE19752538075 patent/DE2538075A1/de not_active Withdrawn
1976
- 1976-07-28 AT AT553976A patent/AT350737B/de not_active IP Right Cessation
- 1976-08-12 PH PH18780A patent/PH13780A/en unknown
- 1976-08-13 US US05/714,045 patent/US4100288A/en not_active Expired - Lifetime
- 1976-08-13 RO RO7687297A patent/RO69457A/ro unknown
- 1976-08-21 ES ES450897A patent/ES450897A1/es not_active Expired
- 1976-08-23 SU SU762389512A patent/SU612631A3/ru active
- 1976-08-24 FI FI762430A patent/FI762430A7/fi not_active Application Discontinuation
- 1976-08-25 CS CS765528A patent/CS192564B2/cs unknown
- 1976-08-25 BG BG034743A patent/BG27546A4/xx unknown
- 1976-08-25 IL IL50355A patent/IL50355A/xx unknown
- 1976-08-25 CH CH1079676A patent/CH622521A5/de not_active IP Right Cessation
- 1976-08-25 DD DD194461A patent/DD127145A5/xx unknown
- 1976-08-25 CS CS778646A patent/CS192599B2/cs unknown
- 1976-08-25 BG BG034062A patent/BG27545A3/xx unknown
- 1976-08-26 SE SE7609495A patent/SE7609495L/xx not_active Application Discontinuation
- 1976-08-26 CA CA259,909A patent/CA1068266A/en not_active Expired
- 1976-08-26 MX MX764858U patent/MX4133E/es unknown
- 1976-08-26 NL NL7609485A patent/NL7609485A/xx not_active Application Discontinuation
- 1976-08-26 LU LU75667A patent/LU75667A1/xx unknown
- 1976-08-26 GB GB35603/76A patent/GB1519719A/en not_active Expired
- 1976-08-26 PL PL1976192020A patent/PL109091B1/pl unknown
- 1976-08-26 BE BE170118A patent/BE845563A/xx unknown
- 1976-08-26 JP JP51102168A patent/JPS5231100A/ja active Pending
- 1976-08-26 AU AU17201/76A patent/AU499926B2/en not_active Expired
- 1976-08-26 IE IE1911/76A patent/IE44069B1/en unknown
- 1976-08-26 PL PL1976213963A patent/PL110724B1/pl unknown
- 1976-08-26 PT PT65521A patent/PT65521B/pt unknown
- 1976-08-26 DK DK386876A patent/DK143278C/da active
- 1976-08-26 GR GR51547A patent/GR61158B/el unknown
- 1976-08-26 HU HU76BO1629A patent/HU176929B/hu unknown
- 1976-08-26 YU YU02081/76A patent/YU208176A/xx unknown
- 1976-08-26 NO NO762932A patent/NO145793C/no unknown
- 1976-08-26 ZA ZA00765120A patent/ZA765120B/xx unknown
- 1976-08-26 NZ NZ181864A patent/NZ181864A/xx unknown
- 1976-08-27 FR FR7625985A patent/FR2321888A1/fr active Granted
- 1976-12-09 ES ES454085A patent/ES454085A1/es not_active Expired
- 1976-12-09 ES ES454087A patent/ES454087A2/es not_active Expired
- 1976-12-09 ES ES454084A patent/ES454084A1/es not_active Expired
- 1976-12-09 ES ES454086A patent/ES454086A1/es not_active Expired
1977
- 1977-05-31 SU SU772485952A patent/SU638262A3/ru active
1980
- 1980-09-18 CH CH699480A patent/CH624115A5/de not_active IP Right Cessation
- 1980-09-18 CH CH699380A patent/CH624114A5/de not_active IP Right Cessation
- 1980-09-18 CH CH699680A patent/CH624117A5/de not_active IP Right Cessation
- 1980-09-18 CH CH699580A patent/CH624116A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
HU176929B (hu)	1981-06-28
IL50355A0 (en)	1976-10-31
ZA765120B (en)	1978-05-30
BE845563A (fr)	1977-02-28
FR2321888A1 (fr)	1977-03-25
SU638262A3 (ru)	1978-12-15
AT350737B (de)	1979-06-11
PL110724B1 (en)	1980-07-31
CH624114A5 (es)	1981-07-15
MX4133E (es)	1982-01-06
IL50355A (en)	1979-11-30
SE7609495L (sv)	1977-02-28
CH624117A5 (es)	1981-07-15
LU75667A1 (es)	1977-09-13
IE44069L (en)	1977-02-27
GR61158B (en)	1978-09-30
US4100288A (en)	1978-07-11
CH624115A5 (es)	1981-07-15
CS192599B2 (en)	1979-08-31
CH622521A5 (es)	1981-04-15
PL192020A1 (pl)	1979-03-12
PL109091B1 (en)	1980-05-31
ES454084A1 (es)	1977-11-16
JPS5231100A (en)	1977-03-09
FI762430A7 (es)	1977-02-28
DK143278B (da)	1981-08-03
CH624116A5 (es)	1981-07-15
AU1720176A (en)	1978-03-02
CA1068266A (en)	1979-12-18
ES450897A1 (es)	1977-12-01
NO762932L (es)	1977-03-01
IE44069B1 (en)	1981-08-12
PT65521A (de)	1976-09-01
DE2538075A1 (de)	1977-03-17
GB1519719A (en)	1978-08-02
NO145793C (no)	1982-06-02
YU208176A (en)	1982-08-31
DK143278C (da)	1981-12-07
ES454085A1 (es)	1977-11-16
NZ181864A (en)	1978-06-20
DK386876A (da)	1977-02-28
SU612631A3 (ru)	1978-06-25
BG27546A4 (bg)	1979-11-12
PT65521B (de)	1978-07-04
FR2321888B1 (es)	1980-01-11
PH13780A (en)	1980-09-26
NO145793B (no)	1982-02-22
BG27545A3 (bg)	1979-11-12
DD127145A5 (es)	1977-09-07
ATA553976A (de)	1978-11-15
ES454087A2 (es)	1977-11-16
RO69457A (ro)	1981-04-30
NL7609485A (nl)	1977-03-01
CS192564B2 (en)	1979-08-31
AU499926B2 (en)	1979-05-03

Publication	Publication Date	Title
ES454086A1 (es)	1977-11-16	Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-norosimorfona nuevas.
ES388885A1 (es)	1973-06-01	Procedimiento para la preparacion de 1-(2-nitrilofenoxi)-2-hidroxi-3-etilaminopropano racemicos u opticamente activo.
ES442886A1 (es)	1977-04-16	Un procedimiento para la preparacion de una nueva d-6-metil-ergolina 2-sustituida y 8-sustituida.
ES378368A1 (es)	1972-06-16	Procedimiento para la preparacion de 2 - (5-nitro-2-imida- zolil) - ben-cimidazoles.
GB1498394A (en)	1978-01-18	Behenic acid esters of 9-thiaxanthene propylidene heterocyclic alcohols and their use in pharmaceutical composition
ES399873A1 (es)	1975-07-01	Procedimiento para la preparacion de nuevos i-fenoxi-2- idroxi-3-alcahilamino propanos recemicos u opticamenacti- vos.
ES400790A1 (es)	1975-01-16	Procedimiento para la preparacion de nuevos acidos 4-(4-bi-fenilil) - 4 - hidroxibutiricos, sus esteres o lactonas.
ES412068A1 (es)	1976-01-01	Un procedimiento para la preparacion de compuestos anaste- sicos locales.
ES442024A1 (es)	1977-03-16	Procedimiento para la preparacion de derivados de propanol.
ES446187A1 (es)	1977-10-01	Un metodo de preparar nuevos compuestos de oxima-eter.
ES406128A1 (es)	1975-07-16	Procedimiento para la preparacion de 4 - (4 - bifenilil) - butiricos y sus esteres.
ES471169A1 (es)	1979-01-16	Un procedimiento para la obtencion de 2-p-clorofenil-1,3,3- trimetil- 4-metilenpiperidina
ES447349A1 (es)	1977-11-01	Un procedimiento para la preparacion de nuevos derivados delacido 8-azaprostanoico.
FI762309A7 (es)	1977-02-14
ES426948A1 (es)	1976-07-16	Procedimiento para la preparacion de nuevas 1,4-benzodiaze-pinas.
ES387136A1 (es)	1974-01-01	Procedimiento de preparacion de nuevas tetrahidro-1,5-ben- zodiazepin-4-onas.
ES477163A1 (es)	1979-10-16	Procedimiento para la preparacion de compuestos de acidos 4-(8x-6,11-dihidro-dibenzo- b.e. -tiepin-11-on-3-il)-4-oxobu- tiricos.
ES437312A1 (es)	1977-02-01	Procedimiento para preparar acidos pirimidin-4-il-indol-3- ilaceticos.
ES484882A1 (es)	1980-06-16	Procedimiento de preparacion de derivados de propionamidoxi-ma
ES428016A1 (es)	1976-09-16	Un procedimiento para preparar nuevos aminoacidos.
ES425324A1 (es)	1976-12-16	Procedimiento para la obtencion de agentes fungicidas.
ES435930A1 (es)	1977-03-16	Un procedimiento para la preparacion de derivados de acido tiazolidinon-acetico.
ES479233A1 (es)	1979-07-16	Procedimiento para la obtencion de derivados de antraquinona.
ES423460A1 (es)	1976-05-01	Procedimiento para la preparacion del acido 7-aminodesace- toxicefalosporanico.
ES448010A1 (es)	1977-07-01	Un procedimiento para preparar nuevos aminoacidos.