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ES384492A1 - Phenylacetylguanidines - Google Patents

Phenylacetylguanidines

Info

Publication number
ES384492A1
ES384492A1 ES384492A ES384492A ES384492A1 ES 384492 A1 ES384492 A1 ES 384492A1 ES 384492 A ES384492 A ES 384492A ES 384492 A ES384492 A ES 384492A ES 384492 A1 ES384492 A1 ES 384492A1
Authority
ES
Spain
Prior art keywords
formula
methyl
chlorine
phenylacetylguanidines
see formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES384492A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wander AG
Original Assignee
Wander AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH257569A external-priority patent/CH511815A/en
Application filed by Wander AG filed Critical Wander AG
Publication of ES384492A1 publication Critical patent/ES384492A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D247/00—Heterocyclic compounds containing rings having two nitrogen atoms as the only ring hetero atoms, according to more than one of groups C07D229/00 - C07D245/00
    • C07D247/02—Heterocyclic compounds containing rings having two nitrogen atoms as the only ring hetero atoms, according to more than one of groups C07D229/00 - C07D245/00 having the nitrogen atoms in positions 1 and 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/48—Nitrogen atoms not forming part of a nitro radical with acyclic hydrocarbon or substituted acyclic hydrocarbon radicals, attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/12—Nitrogen atoms not forming part of a nitro radical
    • C07D239/16—Nitrogen atoms not forming part of a nitro radical acylated on said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Procedure for obtaining acetyl-guanidine derivatives of formula 1b, **(See formula)** where R1 signifies hydrogen, chlorine or methyl, and R2 means chlorine or methyl, and n means 1 or 2. characterized in that a compound of formula V is reduced, **(See formula)** where R1 and R2 have the meanings indicated above, and Y means a group -CH2- or -CH = CH-. (Machine-translation by Google Translate, not legally binding)
ES384492A 1969-02-20 1970-10-14 Phenylacetylguanidines Expired ES384492A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH257569A CH511815A (en) 1969-02-20 1969-02-20 Guanidine derivs as antihypertensive agents
CH469169 1969-03-27
CH1657569 1969-11-07

Publications (1)

Publication Number Publication Date
ES384492A1 true ES384492A1 (en) 1973-06-01

Family

ID=27173786

Family Applications (4)

Application Number Title Priority Date Filing Date
ES376661A Expired ES376661A1 (en) 1969-02-20 1970-02-18 Phenylacetylguanidines
ES384493A Expired ES384493A1 (en) 1969-02-20 1970-10-14 Phenylacetylguanidines
ES384491A Expired ES384491A1 (en) 1969-02-20 1970-10-14 Phenylacetylguanidines
ES384492A Expired ES384492A1 (en) 1969-02-20 1970-10-14 Phenylacetylguanidines

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES376661A Expired ES376661A1 (en) 1969-02-20 1970-02-18 Phenylacetylguanidines
ES384493A Expired ES384493A1 (en) 1969-02-20 1970-10-14 Phenylacetylguanidines
ES384491A Expired ES384491A1 (en) 1969-02-20 1970-10-14 Phenylacetylguanidines

Country Status (17)

Country Link
US (1) US3634508A (en)
AT (2) AT309460B (en)
BE (1) BE746168A (en)
CA (1) CA952111A (en)
CS (2) CS158263B2 (en)
DE (1) DE2006895A1 (en)
DK (1) DK129577B (en)
ES (4) ES376661A1 (en)
FI (1) FI48728C (en)
FR (1) FR2034557B1 (en)
GB (1) GB1298112A (en)
IL (1) IL33925A (en)
NL (1) NL7001836A (en)
NO (1) NO134421C (en)
PL (1) PL80868B1 (en)
SE (1) SE352077B (en)
SU (2) SU508182A3 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2408289A1 (en) * 1974-02-21 1975-09-11 Hoechst Ag SUBSTITUTED DIAMINOGUANIDINE AND THEIR PRODUCTION
DE2901362A1 (en) * 1978-01-25 1979-07-26 Sandoz Ag GUANIDE DERIVATIVES, THEIR PRODUCTION AND USE
DE2931735A1 (en) * 1979-08-04 1981-02-19 Beiersdorf Ag NEW SUBSTITUTED PHENYLACETYLGUANIDINE AND METHOD FOR THE PRODUCTION THEREOF
US4332822A (en) * 1980-02-05 1982-06-01 John Wyeth & Brother Limited Guanidine derivatives
EP0087218B1 (en) * 1982-02-10 1985-05-02 Beecham Group Plc Guanidine derivatives
DE4421536A1 (en) * 1994-06-20 1995-12-21 Hoechst Ag Phenyl-substituted alkenylcarboxylic acid guanidines bearing perfluoroalkyl groups, processes for their preparation, their use as medicaments or diagnostic agents, and medicaments containing them
RU2372329C1 (en) * 2008-06-16 2009-11-10 Государственное образовательное учреждение высшего профессионального образования "Рязанский государственный медицинский университет имени акад. И.П. Павлова Федерального агентства по здравоохранению и социальному развитию" Tris-substituted aminoguanidine derivatives, uses as analytical reagents
GB0916163D0 (en) * 2009-09-15 2009-10-28 Shire Llc Prodrugs of guanfacine
SI3378930T1 (en) 2009-12-16 2020-02-28 Vivabiocell Spa Scaffold for the growth of tissue in vivo
CN102887838A (en) * 2012-10-29 2013-01-23 河南中帅医药科技发展有限公司 Preparation method of guanfacine hydrochloride
CN103058890A (en) * 2012-12-27 2013-04-24 郑州大明药物科技有限公司 Method for preparing guanfacine hydrochloride

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2408694A (en) * 1942-05-29 1946-10-01 Libbey Owens Ford Glass Co Method of preparing acyl guanidines

Also Published As

Publication number Publication date
DK129577C (en) 1975-03-24
ES384491A1 (en) 1974-02-16
GB1298112A (en) 1972-11-29
NO134421B (en) 1976-06-28
FR2034557B1 (en) 1973-12-21
CS158264B2 (en) 1974-10-15
CS158263B2 (en) 1974-10-15
CA952111A (en) 1974-07-30
SU453830A3 (en) 1974-12-15
ES376661A1 (en) 1972-09-16
FR2034557A1 (en) 1970-12-11
BE746168A (en) 1970-08-18
PL80868B1 (en) 1975-08-30
NO134421C (en) 1976-10-06
DK129577B (en) 1974-10-28
SE352077B (en) 1972-12-18
DE2006895A1 (en) 1970-09-10
AT309461B (en) 1973-08-27
IL33925A (en) 1973-08-29
FI48728B (en) 1974-09-02
SU508182A3 (en) 1976-03-25
NL7001836A (en) 1970-08-24
ES384493A1 (en) 1974-06-16
FI48728C (en) 1974-12-10
US3634508A (en) 1972-01-11
IL33925A0 (en) 1970-04-20
AT309460B (en) 1973-08-27

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