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ES2991590A1 - Composition based on cannabinoids - Google Patents

Composition based on cannabinoids Download PDF

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Publication number
ES2991590A1
ES2991590A1 ES202330432A ES202330432A ES2991590A1 ES 2991590 A1 ES2991590 A1 ES 2991590A1 ES 202330432 A ES202330432 A ES 202330432A ES 202330432 A ES202330432 A ES 202330432A ES 2991590 A1 ES2991590 A1 ES 2991590A1
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Prior art keywords
terpenes
hhc
effect
cannabinoids
cannabis
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ES202330432A
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Spanish (es)
Inventor
Guillen Pau Mir
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Individual
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Priority to ES202330432A priority Critical patent/ES2991590A1/en
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Classifications

    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18Treatment of tobacco products or tobacco substitutes
    • A24B15/28Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/302Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by natural substances obtained from animals or plants
    • A24B15/303Plant extracts other than tobacco
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10Chemical features of tobacco products or tobacco substitutes
    • A24B15/16Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A24B15/167Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24DCIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
    • A24D1/00Cigars; Cigarettes
    • A24D1/18Selection of materials, other than tobacco, suitable for smoking
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/06Inhaling appliances shaped like cigars, cigarettes or pipes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Botany (AREA)
  • Agronomy & Crop Science (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Toxicology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Composición a base de cannabinoides que comprende hexahidrocannabinol (HHC) en una cantidad, en volumen, comprendida entre el 87,5% y 94%, y una combinación de terpenos, flavoinoides y/o effect blends en una cantidad entre el 6,0% y 12,5%, consiguiendo un aceite con un amplio espectro de usos desde artículos para fumadores, producto ornamental, cosmético o alimenticio.Composition based on cannabinoids comprising hexahydrocannabinol (HHC) in a quantity, by volume, between 87.5% and 94%, and a combination of terpenes, flavonoids and/or effect blends in a quantity between 6.0% and 12.5%, obtaining an oil with a wide spectrum of uses from smoking articles, ornamental products, cosmetics or food.

Description

DESCRIPCIÓNDESCRIPTION

Composición a base de cannabinoides Composition based on cannabinoids

Sector de la técnicaTechnical sector

La actividad biológica del Cannabis es bien conocida y lo ha llevado a convertirse en una droga recreativa. Sin embargo, con el descubrimiento de una clase de receptores de cannabinoides y la relajación de las leyes que regulan el uso de Cannabis, existe la oportunidad de explorar el potencial de este producto en otros campos. The biological activity of Cannabis is well known and has led to its becoming a recreational drug. However, with the discovery of a class of cannabinoid receptors and the relaxation of laws regulating the use of Cannabis, there is an opportunity to explore the potential of this product in other fields.

Esta invención tiene por objeto una composición a base de cannabinoides, que encuentra su uso en el sector de los productos para fumar, cosméticos, de los aceites esenciales y de los productos alimenticios. This invention relates to a composition based on cannabinoids, which finds its use in the sectors of smoking products, cosmetics, essential oils and food products.

Estado de la técnicaState of the art

El documento US2419935 (A) describe el HHC o hexahidrocannabinol. Se trata de un cannabinoide de origen sintético que, en estado natural, se encuentra en muy bajas concentraciones en las semillas de cannabis. El HHC, según dicho documento, se obtiene a partir del THC o tetrahidrocannabinol, que es el principal componente activo de la marihuana, aunque también lo produce en muy bajas cantidades el cáñamo, que es una planta de cannabis de la misma familia que la marihuana, pero que carece de propiedades psicotrópicas por su bajo nivel de THC, por lo que su consumo es legal en Europa. Document US2419935 (A) describes HHC or hexahydrocannabinol. It is a synthetic cannabinoid that, in its natural state, is found in very low concentrations in cannabis seeds. HHC, according to the document, is obtained from THC or tetrahydrocannabinol, which is the main active component of marijuana, although it is also produced in very low quantities by hemp, which is a cannabis plant from the same family as marijuana, but which lacks psychotropic properties due to its low level of THC, so its consumption is legal in Europe.

Por medio de la planta de cáñamo, y a través de diversos procesos de transformación de sus extractos ricos en cannabinoides, se logra obtener el HHC o hexahidrocannabinol al añadir hidrógeno a los extractos de cannabis, haciendo que este rompa los enlaces de carbono de los cannabinoides, para así lograr un extracto cannábico hidrogenado que permite obtener el hexahidrocannabinol. Through the hemp plant, and through various transformation processes of its extracts rich in cannabinoids, HHC or hexahydrocannabinol is obtained by adding hydrogen to cannabis extracts, causing it to break the carbon bonds of the cannabinoids, thus achieving a hydrogenated cannabis extract that allows hexahydrocannabinol to be obtained.

Entre los efectos del HHC se pueden incluir relajación, alivio del dolor, mejoras en el estado de ánimo y sueño, así como una menor incidencia de efectos secundarios psicoactivos en comparación con el THC. The effects of HHC may include relaxation, pain relief, improvements in mood and sleep, as well as a lower incidence of psychoactive side effects compared to THC.

Se conoce como "efecto séquito" cuando varios compuestos de cannabis trabajan juntos para crear efectos y beneficios únicos. Cuando fumamos o vaporizamos cannabis, nuestro cuerpo absorbe cientos de compuestos botánicos, cada uno con efectos y beneficios únicos, y su comportamiento puede cambiar en presencia de otros compuestos. Esto es lo que se conoce como efecto séquito It is known as the “entourage effect” when several cannabis compounds work together to create unique effects and benefits. When we smoke or vaporize cannabis, our body absorbs hundreds of botanical compounds, each with unique effects and benefits, and its behavior can change in the presence of other compounds. This is what is known as the entourage effect.

Existe una necesidad continua de desarrollar nuevos productos para fumar, cosméticos, los aceites esenciales y productos alimenticios, que se derivan, al menos en parte, de una fuente natural y que presenten el citado efecto séquito para que su consumo aporte una variedad de beneficios sensoriales. There is a continuing need to develop new smoking products, cosmetics, essential oils and food products that are derived, at least in part, from a natural source and that exhibit the entourage effect so that their consumption provides a variety of sensory benefits.

Explicación de la invenciónExplanation of the invention

Con el fin de alcanzar los objetivos propuestos, mencionados en el apartado anterior, la invención propone una composición a base de cannabinoides, que tiene las características de la reivindicación 1. In order to achieve the proposed objectives, mentioned in the previous section, the invention proposes a composition based on cannabinoids, which has the characteristics of claim 1.

La composición a base de cannabinoides de la presente invención comprende: The cannabinoid-based composition of the present invention comprises:

- Hexahidrocannabinol (HHC) en una cantidad, en volumen, comprendida entre el 87,5% y 94%, y - Hexahydrocannabinol (HHC) in an amount, by volume, between 87.5% and 94%, and

- Una combinación de terpenos, flavoinoides y/o mezclas de efectos, que en conjunto forman parte de esta composición en una cantidad comprendida entre el 6,0% y 12,5% en volumen. - A combination of terpenes, flavonoids and/or mixtures of effects, which together form part of this composition in an amount between 6.0% and 12.5% by volume.

La composición a base de cannabinoides es un producto líquido, de consistencia resinosa, con una compleja mezcla de terpenos para conseguir una mejor biodisponibilidad para el cuerpo. Es un producto 100% de origen natural y derivado de cannabis y plantas naturales. El HHC empleado se extrae de cultivos de cáñamo y no contiene D9/D8-THC. La mezcla de terpenos, flavoinoides y effect blends son mezclas específicas de terpenos, tanto de plantas naturales, como terpenos derivados de cannabis. The cannabinoid-based composition is a liquid product, with a resinous consistency, with a complex mixture of terpenes to achieve better bioavailability for the body. It is a 100% natural product derived from cannabis and natural plants. The HHC used is extracted from hemp crops and does not contain D9/D8-THC. The mixture of terpenes, flavonoids and effect blends are specific mixtures of terpenes, both from natural plants and terpenes derived from cannabis.

Los terpenos al ser mezclados a las proporciones correctas con un químico aislado/destilado de la misma planta, que aumenta la unión del químico a nuestros receptores CB1 y CB2 logrando así un “subidón” a través del efecto séquito que aportan. Dependiendo de la mezcla usada se pueden conseguir efectos de la terminología sativa, índica o híbrida, solo variando los terpenos usados. Los terpenos son compuestos orgánicos que se encuentran en plantas, flores, frutas e incluso en algunos insectos; se trata de las moléculas que le dan a cada organismo su perfil distintivo de aroma y sabor. Terpenes, when mixed in the correct proportions with a chemical isolated/distilled from the same plant, increase the chemical’s binding to our CB1 and CB2 receptors, thus achieving a “high” through the entourage effect they provide. Depending on the blend used, effects of sativa, indica, or hybrid terminology can be achieved, just by varying the terpenes used. Terpenes are organic compounds found in plants, flowers, fruits, and even some insects; they are the molecules that give each organism its distinctive aroma and flavor profile.

Por su parte, los flavonoides son pigmentos naturales presentes en los vegetales, que protegen el organismo del daño producido por agentes oxidantes, poseen además propiedades antimicrobianas, anticancerígenas, disminución del riesgo de enfermedades cardíacas, entre otros efectos; también son conocidos por los cultivadores de plantas ornamentales que manipulan el ambiente de las plantas para aumentar la concentración de flavonoides que dan el color a las hojas y a las flores. En términos generales, los flavoinoides solo son terpenos de plantas aislados que se usan para dar sabor (mango, fresa, etc.). Flavonoids are natural pigments found in plants that protect the body from damage caused by oxidizing agents. They also have antimicrobial and anticancer properties, and reduce the risk of heart disease, among other effects. They are also known by ornamental plant growers who manipulate the environment of plants to increase the concentration of flavonoids that give color to leaves and flowers. Generally speaking, flavonoids are only isolated plant terpenes that are used to give flavor (mango, strawberry, etc.).

Por último los effect blends son mezclas específicas para proporcionar un tipo de efecto o sensación. En este caso pueden diferir desde afrodisiaco hasta relajante. Las mezclas de efectos (effect blends) se consiguen, como su propio nombre indica mezclando terpenos o aromas naturales. Finally, effect blends are specific mixtures to provide a type of effect or sensation. In this case, they can range from aphrodisiac to relaxing. Effect blends are achieved, as their name suggests, by mixing terpenes or natural aromas.

El aceite resultante tiene un amplio espectro de usos desde artículos para fumadores, producto ornamental, cosmético o alimenticio. The resulting oil has a wide spectrum of uses, from smoking articles to ornamental products, cosmetics and food.

Esta composición se comercializa en dosis de 0,80 ml, por lo que tanto la mezcla base, como las de los ejemplos que se describen a continuación van referidas a dosis de esta capacidad. La mezcla base es la siguiente: This composition is sold in doses of 0.80 ml, so both the base mixture and the examples described below refer to doses of this capacity. The base mixture is as follows:

- HHC ... 0,7ml - HHC ... 0.7ml

- Terpenos (90/10~CTD) ... 0,05ml - Terpenes (90/10~CTD) ... 0.05ml

- Flavoinoides ... 0,03ml - Flavoinoids ... 0.03ml

- Effect blends ... 0,02ml - Effect blends ... 0.02ml

Esta mezcla es rica en aromas y sabores, y también tiene muy buena sinergia generando efecto séquito, con sabor a cannabis, retrogusto y potenciador de sabor de los flavoinoides (sabores afrutados.) y efectos específicos de los effect blends sin sabor. A partir de esta mezcla se pueden derivar otras con otros efectos y sabores. This blend is rich in aromas and flavours, and also has very good synergy generating entourage effect, with cannabis flavour, aftertaste and flavour enhancer of flavonoids (fruity flavours) and specific effects of flavourless effect blends. From this blend, other blends with other effects and flavours can be derived.

Ejemplo 1, mezcla con efecto séquito, sabor cannabis: Example 1, entourage effect mix, cannabis flavour:

- HHC ... 0,75ml - HHC ... 0.75ml

- Terpenos (90/10~CDT) ... 0,05ml - Terpenes (90/10~CDT) ... 0.05ml

Ejemplo 2, mezcla con efecto sativo (disfrute mayor de los colores y sonidos, estimulación de la creatividad y el pensamiento), sabores afrutados: Example 2, blend with sativa effect (greater enjoyment of colours and sounds, stimulation of creativity and thought), fruity flavours:

- HHC ... 0,75ml - HHC ... 0.75ml

- Flavoinoides ... 0,05ml - Flavoinoids ... 0.05ml

Ejemplo 3, mezcla con efecto séquito, con efecto especifico (afrodisiaco, focus, calma, relax...), sabor floral: Example 3, blend with entourage effect, with specific effect (aphrodisiac, focus, calm, relax...), floral flavour:

- HHC ... 0,75ml - HHC ... 0.75ml

- Effect blends . 0,05ml - Effect blends . 0,05ml

Ejemplo 4, mezcla con efecto séquito, sabor a cannabis y con retrogusto (sabores afrutados, dulces, florales, tabaco, comida.): Example 4, a blend with an entourage effect, cannabis flavour and aftertaste (fruity, sweet, floral, tobacco, food flavours):

- HHC ... 0,72ml - HHC ... 0.72ml

- Terpenos (90/10~CDT) ... 0,05ml - Terpenes (90/10~CDT) ... 0.05ml

- Flavoinoides ...0,03ml - Flavoinoids ...0.03ml

Ejemplo 5, mezcla con efecto séquito, potenciamiento de sabor y retrogusto con los flavoinoides y efectos específicos sin sabor (queda escondido por los otros aromas), haciendo así una combinación muy completa en efectos y sin sabor a cannabis: Example 5, mixture with entourage effect, flavor and aftertaste enhancement with flavonoids and specific effects without flavor (it is hidden by the other aromas), thus making a very complete combination in effects and without cannabis flavor:

- HHC ... 0,73ml - HHC ... 0.73ml

- Flavoinoides . 0,05ml - Flavoinoids . 0.05ml

- Effect blends ... 0,02ml - Effect blends ... 0.02ml

Claims (2)

REIVINDICACIONES 1. - Composición a base de cannabinoides que comprende:1. - Composition based on cannabinoids comprising: - hexahidrocannabinol (HHC) en una cantidad, en volumen, comprendida entre el 87,5% y 94%, y- hexahydrocannabinol (HHC) in a quantity, by volume, between 87.5% and 94%, and - una combinación de terpenos, flavoinoides y/o mezcla de efectos (effect blends) en una cantidad entre el 6,0 % 12,5% en volumen.- a combination of terpenes, flavonoids and/or effect blends in a quantity between 6.0% and 12.5% by volume. 2. - Composición, según la reivindicación 1, en la que para una dosis de 0,80 ml, la mezcla base, es la siguiente:2. - Composition according to claim 1, wherein for a dose of 0.80 ml, the base mixture is the following: - HHC ... 0,7ml- HHC ... 0.7ml - Terpenos ... 0,05ml- Terpenes ... 0.05ml - Flavoinoides ... 0,03ml- Flavoinoids ... 0.03ml - Effect blends ... 0,02ml- Effect blends ... 0.02ml
ES202330432A 2023-05-31 2023-05-31 Composition based on cannabinoids Withdrawn ES2991590A1 (en)

Priority Applications (1)

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ES202330432A ES2991590A1 (en) 2023-05-31 2023-05-31 Composition based on cannabinoids

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022187973A1 (en) * 2021-03-12 2022-09-15 Allied Corp. Dosing regimens of pharmaceutical and nutraceutical mushroom and cannabis compositions and their use to treat cns disorders and improve mental health

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022187973A1 (en) * 2021-03-12 2022-09-15 Allied Corp. Dosing regimens of pharmaceutical and nutraceutical mushroom and cannabis compositions and their use to treat cns disorders and improve mental health

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
GROWLOBBY.COM. "Vaporizador Desechable HHC (1000mg) Kalibloom". growlobby.com [on line], 18/05/2023, [en línea][recuperado el 19/10/2023]. todo el documento; en particular: "Especificaciones de Vaporizador Desechable HHC (1000mg) Kalibloom" *
HEMRAJ D. ¿Qué es exactamente el efecto séquito?. Leafwell.com blog [on line], 02/06/2022 , [en línea][recuperado el 18/10/2023]. todo el documento; en particular: apartado "¿Qué compuestos intervienen en el efecto séquito?". *
MARIJOANA. "Vaper HHC desechable 2 ml 1800 mg". mariajoana.es [on line], 16/01/2023, [en línea][recuperado el 17/10/2023]. todo el docuemnto; en particular: "Descripción del producto" *
VAPORA. "Vape HHC 95% 300 puffs ¿ WHITE RABBIT". Vapora. Vape shop [on line], 22/11/2022, [en línea][recuperado el 18/10/2023]. todo el documento; en particular: "Descripción del producto Vape HHC 95%" *
YPSILÓS. "Vape Desechable Weed (Vapear Sin Nicotina) ¿ 250 Puffs". ypsilos-products.com [tienda on line], 27/04/2023, [en línea][recuperado el 18/10/2023]. todo el documento; en particular: primer párrafo. *

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