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ES2611583T3 - Inhalador de gotitas de líquido dosificadas - Google Patents

Inhalador de gotitas de líquido dosificadas Download PDF

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Publication number
ES2611583T3
ES2611583T3 ES10822312.4T ES10822312T ES2611583T3 ES 2611583 T3 ES2611583 T3 ES 2611583T3 ES 10822312 T ES10822312 T ES 10822312T ES 2611583 T3 ES2611583 T3 ES 2611583T3
Authority
ES
Spain
Prior art keywords
reservoir
medicament
nozzle
proximal
power supply
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES10822312.4T
Other languages
English (en)
Inventor
Lennart Brunnberg
Martin Karlsson
Nils Ronquist
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SHL Group AB
Original Assignee
SHL Group AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SHL Group AB filed Critical SHL Group AB
Application granted granted Critical
Publication of ES2611583T3 publication Critical patent/ES2611583T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007—Syringe-type or piston-type sprayers or atomisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0066—Inhalators with dosage or measuring devices with means for varying the dose size
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0095—Preventing manual activation in absence of inhalation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0096—Hindering inhalation before activation of the dispenser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31553—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe without axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Mechanical Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)

Abstract

Dispositivo de inhalación de gotitas de líquido dosificadas para administrar medicamentos, que comprende: - una carcasa (10) tubular alargada que tiene extremos distal y proximal opuestos; - un soporte (24) de depósito de medicamento conectado de manera liberable a dicha carcasa (10) mediante primeros medios (20, 22) de acoplamiento; - un depósito (26) de medicamento dispuesto dentro de dicho soporte (24) de depósito de medicamento, en el que dicho depósito comprende una forma tubular que tiene al menos una cámara que puede contener una composición de medicamento, una abertura proximal para permitir que la composición de medicamento se expulse del mismo, y al menos un pistón (42) axialmente móvil; - un botón (108) de dosificación accesible fuera del extremo distal de la carcasa (10) para ajustar una dosis que va a expulsarse acumulando una fuerza de rotación; - un mecanismo de fuente de alimentación que puede convertir la fuerza de rotación en una fuerza axial que va a aplicarse al pistón (42) y crear de ese modo una presión dentro de dicho depósito (26) de medicamento; - medios (134) de activación en conexión mecánica con el mecanismo de fuente de alimentación; - una boquilla (36) en conexión mecánica con la parte proximal del soporte (24) de depósito, donde la boquilla (36) comprende una zona de acoplamiento con la boca y una abertura para aire; - un generador (38) de gotitas que tiene una pluralidad de orificios pasantes y dispuesto en la boquilla (36), en el que los orificios están en comunicación de fluido con la abertura proximal del depósito (40) y con la boquilla (36); caracterizado porque el dispositivo comprende además un elemento (100) de amortiguación de rotación en conexión mecánica con el mecanismo de fuente de alimentación para amortiguar un máximo de presión inicial dentro de dicho depósito (26) de medicamento, y en el que dicho elemento (100) de amortiguación de rotación comprende una parte proximal conectada de manera rotacional a un árbol (64) y una parte distal que penetra en un compartimento (110) en dicho botón (108) de dosificación, compartimento que se llena con un material altamente viscoso.

Description

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Claims (1)

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    imagen2
ES10822312.4T 2009-10-08 2010-09-13 Inhalador de gotitas de líquido dosificadas Active ES2611583T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0950738 2009-10-08
SE0950738 2009-10-08
PCT/SE2010/050972 WO2011043712A1 (en) 2009-10-08 2010-09-13 Metered liquid droplet inhaler

Publications (1)

Publication Number Publication Date
ES2611583T3 true ES2611583T3 (es) 2017-05-09

Family

ID=43856995

Family Applications (1)

Application Number Title Priority Date Filing Date
ES10822312.4T Active ES2611583T3 (es) 2009-10-08 2010-09-13 Inhalador de gotitas de líquido dosificadas

Country Status (13)

Country Link
US (1) US9750900B2 (es)
EP (1) EP2485793B1 (es)
JP (1) JP5430769B2 (es)
CN (1) CN102639176B (es)
AU (1) AU2010303985B2 (es)
BR (1) BR112012008236A2 (es)
DK (1) DK2485793T3 (es)
ES (1) ES2611583T3 (es)
MX (1) MX2012004123A (es)
RU (1) RU2492878C1 (es)
TW (1) TWI432232B (es)
WO (1) WO2011043712A1 (es)
ZA (1) ZA201202527B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6000946B2 (ja) 2010-07-12 2016-10-05 クセリア ファーマシューティカルズ エーピーエスＸｅｌｌｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ ＡｐＳ 肺感染症の治療のための組成物
ES2770764T3 (es) * 2011-07-13 2020-07-03 Pharmaxis Ltd Mejoras relacionadas con dispositivos de suministro
ES2877100T3 (es) 2011-07-13 2021-11-16 Pharmaxis Ltd Mejoras relacionadas con los dispositivos de suministro
TWI599377B (zh) * 2013-01-15 2017-09-21 卡貝歐洲有限公司 藥物輸送裝置
TW201440825A (zh) 2013-01-15 2014-11-01 Carebay Europe Ltd 藥物輸送裝置
WO2015154865A2 (en) * 2014-04-07 2015-10-15 Boehringer Ingelheim International Gmbh Inhalation training device and system for practicing of an inhalation process of a patient
EP3129087B1 (en) 2014-04-07 2020-02-26 Boehringer Ingelheim International GmbH Method, electronic device, inhalation training system for practicing and/or controlling an inhalation process of a patient
TR201906108T4 (tr) 2014-10-03 2019-05-21 Xellia Pharmaceuticals Aps İnhalasyon cihazı.
EP3064241A1 (en) 2015-03-06 2016-09-07 Carebay Europe Ltd. Power supply mechanism
DK3682915T3 (da) * 2015-10-30 2023-06-19 Acelrx Pharmaceuticals Inc Anordning og fremgangsmåder til afgivelse af orale transmucosale doseringsformer
GB2544477A (en) * 2015-11-16 2017-05-24 3M Innovative Properties Co Improvements in or relating to medical actuators
GB2544478A (en) * 2015-11-16 2017-05-24 3M Innovative Properties Co Improvements in metered dose inhaler devices
US10081031B1 (en) * 2017-03-15 2018-09-25 The Boeing Company Reusable applicators and related methods
CN110785194B (zh) * 2017-07-12 2022-05-03 费森尤斯维尔公司 具有用于接纳注射器的保持装置的泵装置
CA3091961A1 (en) * 2018-03-07 2019-09-12 Astrazeneca Ab Inhaler
AU2019355852B2 (en) * 2018-10-02 2024-10-31 Boston Scientific Scimed, Inc. Devices for fluidization and delivering a powdered agent
GB2585206B (en) 2019-07-01 2021-08-11 Merxin Ltd Portable inhaler
NL2023873B1 (nl) 2019-09-20 2021-05-25 Medspray B V Verstuiverinrichting en werkwijze voor het prepareren daarvan, alsmede een houder daarvoor

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK302890D0 (da) * 1990-12-21 1990-12-21 Novo Nordisk As Dispenser
JP3568959B2 (ja) * 1995-03-07 2004-09-22 イーライ・リリー・アンド・カンパニー 再利用可能な投薬装置
EP1020233A1 (en) * 1999-01-13 2000-07-19 The Procter & Gamble Company Dosing and delivering system
AU776361B2 (en) * 1999-08-03 2004-09-09 Pharmacia Ab Liquid delivery container
EP1225942B1 (en) 1999-11-02 2005-02-09 SHL Medical AB Inhalator with aerosolizing unit
AR026914A1 (es) * 1999-12-11 2003-03-05 Glaxo Group Ltd Distribuidor de medicamento
NL1016030C1 (nl) 2000-08-28 2002-03-01 Aquamarijn Holding B V Sproei inrichting met een nozzleplaat, een nozzleplaat, alsmede werkwijzen ter vervaardiging en voor toepassing van een dergelijke nozzleplaat.
US6899699B2 (en) * 2001-01-05 2005-05-31 Novo Nordisk A/S Automatic injection device with reset feature
SE0100418D0 (sv) * 2001-02-08 2001-02-08 Pharmacia Ab Liquid delivery device and use method
US6758837B2 (en) * 2001-02-08 2004-07-06 Pharmacia Ab Liquid delivery device and method of use thereof
CA2441100C (en) * 2001-03-20 2013-05-21 Trudell Medical International Nebulizer apparatus with an adjustable fluid orifice
ATE434455T1 (de) 2002-09-24 2009-07-15 Shl Group Ab Injektionsvorrichtung
DE102005010965B3 (de) 2005-03-10 2006-08-03 Medspray Xmems Bv Inhalator mit einem Mischkanal zum Erzeugen eines zu inhalierenden Aerosols
GB2425062B (en) * 2005-04-06 2010-07-21 Cilag Ag Int Injection device
DK1885415T3 (da) 2005-06-01 2013-08-05 Shl Group Ab Indretning til afgivelse af et medikament
DE202005021773U1 (de) * 2005-06-01 2010-01-07 Shl Group Ab Medikamentenabgabevorrichtung
US9011386B2 (en) * 2005-06-01 2015-04-21 Shl Group Ab Device for delivering medicament
DE102005060929A1 (de) * 2005-09-14 2007-03-15 Tecpharma Licensing Ag Injektionsvorrichtung mit Zweiwege-Rutschkupplung
WO2007099044A1 (en) * 2006-03-03 2007-09-07 Shl Medical Ab Medical device with orientation sensitive priming mechanism
WO2007123945A2 (en) * 2006-04-21 2007-11-01 Aradigm Corporation Mechanical single dose intrapulmonary drug delivery devices
WO2008020023A1 (en) * 2006-08-18 2008-02-21 Shl Group Ab Device for delivering medicament encompassing a pressure release mechanism
WO2008087071A1 (en) * 2007-01-17 2008-07-24 Shl Group Ab Device for delivering medicament
WO2010052479A1 (en) * 2008-11-06 2010-05-14 Medispray Laboratories Pvt. Ltd Inhaler device

Also Published As

Publication number Publication date
JP5430769B2 (ja) 2014-03-05
ZA201202527B (en) 2012-12-27
MX2012004123A (es) 2012-09-07
TW201125598A (en) 2011-08-01
EP2485793A1 (en) 2012-08-15
US20120216805A1 (en) 2012-08-30
BR112012008236A2 (pt) 2016-03-08
EP2485793B1 (en) 2016-10-26
US9750900B2 (en) 2017-09-05
DK2485793T3 (en) 2017-02-06
AU2010303985A1 (en) 2012-05-17
TWI432232B (zh) 2014-04-01
EP2485793A4 (en) 2014-10-08
RU2492878C1 (ru) 2013-09-20
JP2013507172A (ja) 2013-03-04
CN102639176B (zh) 2014-07-02
CN102639176A (zh) 2012-08-15
AU2010303985B2 (en) 2012-09-13
WO2011043712A1 (en) 2011-04-14

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