ES2640385T3 - Composición que contiene cuerpos oleaginosos, ácidos grasos, agentes tensioactivos de aminoácido y N-metil-N-acilglucaminas - Google Patents
Composición que contiene cuerpos oleaginosos, ácidos grasos, agentes tensioactivos de aminoácido y N-metil-N-acilglucaminas Download PDFInfo
- Publication number
- ES2640385T3 ES2640385T3 ES14718513.6T ES14718513T ES2640385T3 ES 2640385 T3 ES2640385 T3 ES 2640385T3 ES 14718513 T ES14718513 T ES 14718513T ES 2640385 T3 ES2640385 T3 ES 2640385T3
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- Prior art keywords
- component
- methyl
- acyl
- amino acid
- composition containing
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- 239000000203 mixture Substances 0.000 title abstract description 20
- 235000014113 dietary fatty acids Nutrition 0.000 title abstract description 9
- 239000000194 fatty acid Substances 0.000 title abstract description 9
- 229930195729 fatty acid Natural products 0.000 title abstract description 9
- 239000004094 surface-active agent Substances 0.000 title abstract description 6
- 150000001413 amino acids Chemical class 0.000 title abstract 2
- 150000004665 fatty acids Chemical class 0.000 title description 6
- -1 acyl aspartate Chemical compound 0.000 abstract description 45
- 150000003839 salts Chemical class 0.000 abstract description 7
- DHMQDGOQFOQNFH-UHFFFAOYSA-M Aminoacetate Chemical compound NCC([O-])=O DHMQDGOQFOQNFH-UHFFFAOYSA-M 0.000 abstract description 4
- 239000003945 anionic surfactant Substances 0.000 abstract description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 2
- 229940024606 amino acid Drugs 0.000 abstract 2
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 229940009098 aspartate Drugs 0.000 abstract 1
- 229960003237 betaine Drugs 0.000 abstract 1
- 229930195712 glutamate Natural products 0.000 abstract 1
- 229940071089 sarcosinate Drugs 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 description 12
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 9
- 239000011734 sodium Substances 0.000 description 9
- 239000002253 acid Substances 0.000 description 7
- 229910019142 PO4 Inorganic materials 0.000 description 6
- 125000003118 aryl group Chemical group 0.000 description 6
- 239000010452 phosphate Substances 0.000 description 6
- 235000021317 phosphate Nutrition 0.000 description 6
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 6
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 5
- 150000007513 acids Chemical class 0.000 description 5
- 125000003545 alkoxy group Chemical group 0.000 description 5
- 125000003710 aryl alkyl group Chemical group 0.000 description 5
- 150000002148 esters Chemical class 0.000 description 5
- 239000001341 hydroxy propyl starch Substances 0.000 description 5
- 235000013828 hydroxypropyl starch Nutrition 0.000 description 5
- 125000004432 carbon atom Chemical group C* 0.000 description 4
- 125000000753 cycloalkyl group Chemical group 0.000 description 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 3
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 150000001298 alcohols Chemical class 0.000 description 3
- 150000001408 amides Chemical class 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 3
- WSDISUOETYTPRL-UHFFFAOYSA-N dmdm hydantoin Chemical compound CC1(C)N(CO)C(=O)N(CO)C1=O WSDISUOETYTPRL-UHFFFAOYSA-N 0.000 description 3
- 239000000839 emulsion Substances 0.000 description 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 3
- 229910052708 sodium Inorganic materials 0.000 description 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 2
- FKKAGFLIPSSCHT-UHFFFAOYSA-N 1-dodecoxydodecane;sulfuric acid Chemical compound OS(O)(=O)=O.CCCCCCCCCCCCOCCCCCCCCCCCC FKKAGFLIPSSCHT-UHFFFAOYSA-N 0.000 description 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 2
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical class [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 2
- 239000004375 Dextrin Substances 0.000 description 2
- 229920001353 Dextrin Polymers 0.000 description 2
- 239000004166 Lanolin Substances 0.000 description 2
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 description 2
- 125000001931 aliphatic group Chemical group 0.000 description 2
- 229910001413 alkali metal ion Inorganic materials 0.000 description 2
- 229910052784 alkaline earth metal Inorganic materials 0.000 description 2
- 150000001342 alkaline earth metals Chemical class 0.000 description 2
- 125000004183 alkoxy alkyl group Chemical group 0.000 description 2
- 150000008051 alkyl sulfates Chemical class 0.000 description 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
- 235000010323 ascorbic acid Nutrition 0.000 description 2
- 229960005070 ascorbic acid Drugs 0.000 description 2
- 239000011668 ascorbic acid Substances 0.000 description 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 2
- 235000019425 dextrin Nutrition 0.000 description 2
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 2
- 239000000499 gel Substances 0.000 description 2
- 229910001385 heavy metal Inorganic materials 0.000 description 2
- 125000000623 heterocyclic group Chemical group 0.000 description 2
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 description 2
- 235000014655 lactic acid Nutrition 0.000 description 2
- 239000004310 lactic acid Substances 0.000 description 2
- 235000019388 lanolin Nutrition 0.000 description 2
- 229940039717 lanolin Drugs 0.000 description 2
- 229960003512 nicotinic acid Drugs 0.000 description 2
- LXCFILQKKLGQFO-UHFFFAOYSA-N p-hydroxybenzoic acid methyl ester Natural products COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 2
- 229960005323 phenoxyethanol Drugs 0.000 description 2
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 2
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 description 2
- 108700004121 sarkosyl Proteins 0.000 description 2
- 159000000000 sodium salts Chemical class 0.000 description 2
- 239000002562 thickening agent Substances 0.000 description 2
- 150000003626 triacylglycerols Chemical class 0.000 description 2
- WTVHAMTYZJGJLJ-UHFFFAOYSA-N (+)-(4S,8R)-8-epi-beta-bisabolol Natural products CC(C)=CCCC(C)C1(O)CCC(C)=CC1 WTVHAMTYZJGJLJ-UHFFFAOYSA-N 0.000 description 1
- RGZSQWQPBWRIAQ-CABCVRRESA-N (-)-alpha-Bisabolol Chemical compound CC(C)=CCC[C@](C)(O)[C@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-CABCVRRESA-N 0.000 description 1
- SQTVAHSLDLVHHX-UHFFFAOYSA-M (2,6-dimethyl-4-phenylheptan-4-yl)-(2-ethoxyethyl)-dimethylazanium chloride Chemical compound [Cl-].CCOCC[N+](C)(C)C(CC(C)C)(CC(C)C)C1=CC=CC=C1 SQTVAHSLDLVHHX-UHFFFAOYSA-M 0.000 description 1
- CRDAMVZIKSXKFV-FBXUGWQNSA-N (2-cis,6-cis)-farnesol Chemical compound CC(C)=CCC\C(C)=C/CC\C(C)=C/CO CRDAMVZIKSXKFV-FBXUGWQNSA-N 0.000 description 1
- 239000000260 (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol Substances 0.000 description 1
- XMAYWYJOQHXEEK-OZXSUGGESA-N (2R,4S)-ketoconazole Chemical compound C1CN(C(=O)C)CCN1C(C=C1)=CC=C1OC[C@@H]1O[C@@](CN2C=NC=C2)(C=2C(=CC(Cl)=CC=2)Cl)OC1 XMAYWYJOQHXEEK-OZXSUGGESA-N 0.000 description 1
- NWXADGGHXYSLSP-IYWMVGAKSA-N (3s,4s,5s,6r)-1,8-diphenylocta-1,7-diene-2,3,4,5,6,7-hexol Chemical compound OC([C@H](O)[C@@H](O)[C@H](O)[C@H](O)C(O)=CC=1C=CC=CC=1)=CC1=CC=CC=C1 NWXADGGHXYSLSP-IYWMVGAKSA-N 0.000 description 1
- 229940031723 1,2-octanediol Drugs 0.000 description 1
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- RZRNAYUHWVFMIP-KTKRTIGZSA-N 1-oleoylglycerol Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(O)CO RZRNAYUHWVFMIP-KTKRTIGZSA-N 0.000 description 1
- IBLKWZIFZMJLFL-UHFFFAOYSA-N 1-phenoxypropan-2-ol Chemical compound CC(O)COC1=CC=CC=C1 IBLKWZIFZMJLFL-UHFFFAOYSA-N 0.000 description 1
- DHVLDKHFGIVEIP-UHFFFAOYSA-N 2-bromo-2-(bromomethyl)pentanedinitrile Chemical compound BrCC(Br)(C#N)CCC#N DHVLDKHFGIVEIP-UHFFFAOYSA-N 0.000 description 1
- 125000004398 2-methyl-2-butyl group Chemical group CC(C)(CC)* 0.000 description 1
- 125000004918 2-methyl-2-pentyl group Chemical group CC(C)(CCC)* 0.000 description 1
- 125000004922 2-methyl-3-pentyl group Chemical group CC(C)C(CC)* 0.000 description 1
- 229940100555 2-methyl-4-isothiazolin-3-one Drugs 0.000 description 1
- 125000004493 2-methylbut-1-yl group Chemical group CC(C*)CC 0.000 description 1
- ANZUDYZHSVGBRF-UHFFFAOYSA-N 3-ethylnonane-1,2,3-triol Chemical compound CCCCCCC(O)(CC)C(O)CO ANZUDYZHSVGBRF-UHFFFAOYSA-N 0.000 description 1
- 229940099451 3-iodo-2-propynylbutylcarbamate Drugs 0.000 description 1
- WYVVKGNFXHOCQV-UHFFFAOYSA-N 3-iodoprop-2-yn-1-yl butylcarbamate Chemical compound CCCCNC(=O)OCC#CI WYVVKGNFXHOCQV-UHFFFAOYSA-N 0.000 description 1
- 125000004917 3-methyl-2-butyl group Chemical group CC(C(C)*)C 0.000 description 1
- 125000004919 3-methyl-2-pentyl group Chemical group CC(C(C)*)CC 0.000 description 1
- 125000004921 3-methyl-3-pentyl group Chemical group CC(CC)(CC)* 0.000 description 1
- OSDLLIBGSJNGJE-UHFFFAOYSA-N 4-chloro-3,5-dimethylphenol Chemical compound CC1=CC(O)=CC(C)=C1Cl OSDLLIBGSJNGJE-UHFFFAOYSA-N 0.000 description 1
- 125000004920 4-methyl-2-pentyl group Chemical group CC(CC(C)*)C 0.000 description 1
- 229940100484 5-chloro-2-methyl-4-isothiazolin-3-one Drugs 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 1
- 241000416162 Astragalus gummifer Species 0.000 description 1
- 239000005711 Benzoic acid Substances 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 description 1
- LVDKZNITIUWNER-UHFFFAOYSA-N Bronopol Chemical compound OCC(Br)(CO)[N+]([O-])=O LVDKZNITIUWNER-UHFFFAOYSA-N 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 1
- RKWGIWYCVPQPMF-UHFFFAOYSA-N Chloropropamide Chemical compound CCCNC(=O)NS(=O)(=O)C1=CC=C(Cl)C=C1 RKWGIWYCVPQPMF-UHFFFAOYSA-N 0.000 description 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical class [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 1
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
- XSISQURPIRTMAY-UHFFFAOYSA-N Hydroxyethyl glycine Chemical compound NCC(=O)OCCO XSISQURPIRTMAY-UHFFFAOYSA-N 0.000 description 1
- 239000005639 Lauric acid Substances 0.000 description 1
- 229920000881 Modified starch Polymers 0.000 description 1
- BACYUWVYYTXETD-UHFFFAOYSA-N N-Lauroylsarcosine Chemical compound CCCCCCCCCCCC(=O)N(C)CC(O)=O BACYUWVYYTXETD-UHFFFAOYSA-N 0.000 description 1
- FOUZISDNESEYLX-UHFFFAOYSA-N N-hydroxyethyl glycine Natural products OCCNCC(O)=O FOUZISDNESEYLX-UHFFFAOYSA-N 0.000 description 1
- 241000209490 Nymphaea Species 0.000 description 1
- 235000016791 Nymphaea odorata subsp odorata Nutrition 0.000 description 1
- ALQSHHUCVQOPAS-UHFFFAOYSA-N Pentane-1,5-diol Chemical compound OCCCCCO ALQSHHUCVQOPAS-UHFFFAOYSA-N 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 1
- 229910006127 SO3X Inorganic materials 0.000 description 1
- 229910021607 Silver chloride Inorganic materials 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- 235000019486 Sunflower oil Nutrition 0.000 description 1
- 229920001615 Tragacanth Polymers 0.000 description 1
- PHYFQTYBJUILEZ-UHFFFAOYSA-N Trioleoylglycerol Natural products CCCCCCCCC=CCCCCCCCC(=O)OCC(OC(=O)CCCCCCCC=CCCCCCCCC)COC(=O)CCCCCCCC=CCCCCCCCC PHYFQTYBJUILEZ-UHFFFAOYSA-N 0.000 description 1
- 229930003471 Vitamin B2 Natural products 0.000 description 1
- 229930003537 Vitamin B3 Natural products 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- NENOAJSZZPODGJ-OIMNJJJWSA-N [(2r)-2-[(2r,3r,4s)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] octanoate Chemical compound CCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O NENOAJSZZPODGJ-OIMNJJJWSA-N 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 229910052783 alkali metal Inorganic materials 0.000 description 1
- 229960000458 allantoin Drugs 0.000 description 1
- RGZSQWQPBWRIAQ-LSDHHAIUSA-N alpha-Bisabolol Natural products CC(C)=CCC[C@@](C)(O)[C@@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-LSDHHAIUSA-N 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 230000001741 anti-phlogistic effect Effects 0.000 description 1
- 239000000043 antiallergic agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- UREZNYTWGJKWBI-UHFFFAOYSA-M benzethonium chloride Chemical compound [Cl-].C1=CC(C(C)(C)CC(C)(C)C)=CC=C1OCCOCC[N+](C)(C)CC1=CC=CC=C1 UREZNYTWGJKWBI-UHFFFAOYSA-M 0.000 description 1
- 229960001950 benzethonium chloride Drugs 0.000 description 1
- 235000010233 benzoic acid Nutrition 0.000 description 1
- 230000000035 biogenic effect Effects 0.000 description 1
- 229960002685 biotin Drugs 0.000 description 1
- 235000020958 biotin Nutrition 0.000 description 1
- 239000011616 biotin Substances 0.000 description 1
- 229940036350 bisabolol Drugs 0.000 description 1
- HHGZABIIYIWLGA-UHFFFAOYSA-N bisabolol Natural products CC1CCC(C(C)(O)CCC=C(C)C)CC1 HHGZABIIYIWLGA-UHFFFAOYSA-N 0.000 description 1
- 229940067596 butylparaben Drugs 0.000 description 1
- 229960001631 carbomer Drugs 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 125000004181 carboxyalkyl group Chemical group 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 150000001768 cations Chemical group 0.000 description 1
- 239000001913 cellulose Chemical class 0.000 description 1
- 229920002678 cellulose Chemical class 0.000 description 1
- 229960001927 cetylpyridinium chloride Drugs 0.000 description 1
- YMKDRGPMQRFJGP-UHFFFAOYSA-M cetylpyridinium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 YMKDRGPMQRFJGP-UHFFFAOYSA-M 0.000 description 1
- WOWHHFRSBJGXCM-UHFFFAOYSA-M cetyltrimethylammonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+](C)(C)C WOWHHFRSBJGXCM-UHFFFAOYSA-M 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- DHNRXBZYEKSXIM-UHFFFAOYSA-N chloromethylisothiazolinone Chemical compound CN1SC(Cl)=CC1=O DHNRXBZYEKSXIM-UHFFFAOYSA-N 0.000 description 1
- 229960005443 chloroxylenol Drugs 0.000 description 1
- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 description 1
- 229940073507 cocamidopropyl betaine Drugs 0.000 description 1
- 229940065856 cocoyl glycinate Drugs 0.000 description 1
- 229940079840 cocoyl isethionate Drugs 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 239000003246 corticosteroid Substances 0.000 description 1
- 229960001334 corticosteroids Drugs 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 125000004093 cyano group Chemical group *C#N 0.000 description 1
- SOROIESOUPGGFO-UHFFFAOYSA-N diazolidinylurea Chemical compound OCNC(=O)N(CO)C1N(CO)C(=O)N(CO)C1=O SOROIESOUPGGFO-UHFFFAOYSA-N 0.000 description 1
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- 229940093915 gynecological organic acid Drugs 0.000 description 1
- 125000001475 halogen functional group Chemical group 0.000 description 1
- XXMIOPMDWAUFGU-UHFFFAOYSA-N hexane-1,6-diol Chemical compound OCCCCCCO XXMIOPMDWAUFGU-UHFFFAOYSA-N 0.000 description 1
- 125000001183 hydrocarbyl group Chemical group 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 description 1
- ZCTXEAQXZGPWFG-UHFFFAOYSA-N imidurea Chemical compound O=C1NC(=O)N(CO)C1NC(=O)NCNC(=O)NC1C(=O)NC(=O)N1CO ZCTXEAQXZGPWFG-UHFFFAOYSA-N 0.000 description 1
- 150000007529 inorganic bases Chemical class 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- SUMDYPCJJOFFON-UHFFFAOYSA-N isethionic acid Chemical class OCCS(O)(=O)=O SUMDYPCJJOFFON-UHFFFAOYSA-N 0.000 description 1
- 125000001972 isopentyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C([H])([H])* 0.000 description 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 description 1
- 229960004125 ketoconazole Drugs 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000003589 local anesthetic agent Substances 0.000 description 1
- 229960005015 local anesthetics Drugs 0.000 description 1
- 159000000003 magnesium salts Chemical class 0.000 description 1
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 description 1
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 description 1
- BEGLCMHJXHIJLR-UHFFFAOYSA-N methylisothiazolinone Chemical compound CN1SC=CC1=O BEGLCMHJXHIJLR-UHFFFAOYSA-N 0.000 description 1
- 229960002216 methylparaben Drugs 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000019426 modified starch Nutrition 0.000 description 1
- 125000006606 n-butoxy group Chemical group 0.000 description 1
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 125000001280 n-hexyl group Chemical group C(CCCCC)* 0.000 description 1
- 125000000740 n-pentyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- OZGNYLLQHRPOBR-DHZHZOJOSA-N naftifine Chemical compound C=1C=CC2=CC=CC=C2C=1CN(C)C\C=C\C1=CC=CC=C1 OZGNYLLQHRPOBR-DHZHZOJOSA-N 0.000 description 1
- 229960004313 naftifine Drugs 0.000 description 1
- 125000001624 naphthyl group Chemical group 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- DFPAKSUCGFBDDF-UHFFFAOYSA-N nicotinic acid amide Natural products NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- AEIJTFQOBWATKX-UHFFFAOYSA-N octane-1,2-diol Chemical compound CCCCCCC(O)CO AEIJTFQOBWATKX-UHFFFAOYSA-N 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 229960003483 oxiconazole Drugs 0.000 description 1
- QRJJEGAJXVEBNE-MOHJPFBDSA-N oxiconazole Chemical compound ClC1=CC(Cl)=CC=C1CO\N=C(C=1C(=CC(Cl)=CC=1)Cl)\CN1C=NC=C1 QRJJEGAJXVEBNE-MOHJPFBDSA-N 0.000 description 1
- 229940086539 peg-7 glyceryl cocoate Drugs 0.000 description 1
- 125000003538 pentan-3-yl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])C([H])([H])[H] 0.000 description 1
- UWJJYHHHVWZFEP-UHFFFAOYSA-N pentane-1,1-diol Chemical compound CCCCC(O)O UWJJYHHHVWZFEP-UHFFFAOYSA-N 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 229940106026 phenoxyisopropanol Drugs 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- CTYRPMDGLDAWRQ-UHFFFAOYSA-N phenyl hydrogen sulfate Chemical compound OS(=O)(=O)OC1=CC=CC=C1 CTYRPMDGLDAWRQ-UHFFFAOYSA-N 0.000 description 1
- CGIHFIDULQUVJG-UHFFFAOYSA-N phytantriol Chemical compound CC(C)CCCC(C)CCCC(C)CCCC(C)(O)C(O)CO CGIHFIDULQUVJG-UHFFFAOYSA-N 0.000 description 1
- CGIHFIDULQUVJG-VNTMZGSJSA-N phytantriol Natural products CC(C)CCC[C@H](C)CCC[C@H](C)CCC[C@@](C)(O)[C@H](O)CO CGIHFIDULQUVJG-VNTMZGSJSA-N 0.000 description 1
- 229950001046 piroctone Drugs 0.000 description 1
- BTSZTGGZJQFALU-UHFFFAOYSA-N piroctone olamine Chemical compound NCCO.CC(C)(C)CC(C)CC1=CC(C)=CC(=O)N1O BTSZTGGZJQFALU-UHFFFAOYSA-N 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 description 1
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 description 1
- 229960003415 propylparaben Drugs 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- FGVVTMRZYROCTH-UHFFFAOYSA-N pyridine-2-thiol N-oxide Chemical compound [O-][N+]1=CC=CC=C1S FGVVTMRZYROCTH-UHFFFAOYSA-N 0.000 description 1
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 description 1
- 229960002026 pyrithione Drugs 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 150000003873 salicylate salts Chemical class 0.000 description 1
- 229930195734 saturated hydrocarbon Natural products 0.000 description 1
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- JNMWHTHYDQTDQZ-UHFFFAOYSA-N selenium sulfide Chemical compound S=[Se]=S JNMWHTHYDQTDQZ-UHFFFAOYSA-N 0.000 description 1
- 239000002453 shampoo Substances 0.000 description 1
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 229940048106 sodium lauroyl isethionate Drugs 0.000 description 1
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 description 1
- RPACBEVZENYWOL-XFULWGLBSA-M sodium;(2r)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylate Chemical compound [Na+].C=1C=C(Cl)C=CC=1OCCCCCC[C@]1(C(=O)[O-])CO1 RPACBEVZENYWOL-XFULWGLBSA-M 0.000 description 1
- ADWNFGORSPBALY-UHFFFAOYSA-M sodium;2-[dodecyl(methyl)amino]acetate Chemical compound [Na+].CCCCCCCCCCCCN(C)CC([O-])=O ADWNFGORSPBALY-UHFFFAOYSA-M 0.000 description 1
- BRMSVEGRHOZCAM-UHFFFAOYSA-M sodium;2-dodecanoyloxyethanesulfonate Chemical compound [Na+].CCCCCCCCCCCC(=O)OCCS([O-])(=O)=O BRMSVEGRHOZCAM-UHFFFAOYSA-M 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
- 239000004334 sorbic acid Substances 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- WSWCOQWTEOXDQX-MQQKCMAXSA-N sorbic acid group Chemical group C(\C=C\C=C\C)(=O)O WSWCOQWTEOXDQX-MQQKCMAXSA-N 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 125000003107 substituted aryl group Chemical group 0.000 description 1
- 239000002600 sunflower oil Substances 0.000 description 1
- DOMXUEMWDBAQBQ-WEVVVXLNSA-N terbinafine Chemical compound C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 DOMXUEMWDBAQBQ-WEVVVXLNSA-N 0.000 description 1
- 229960002722 terbinafine Drugs 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 229940042585 tocopherol acetate Drugs 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- CRDAMVZIKSXKFV-UHFFFAOYSA-N trans-Farnesol Natural products CC(C)=CCCC(C)=CCCC(C)=CCO CRDAMVZIKSXKFV-UHFFFAOYSA-N 0.000 description 1
- ICUTUKXCWQYESQ-UHFFFAOYSA-N triclocarban Chemical compound C1=CC(Cl)=CC=C1NC(=O)NC1=CC=C(Cl)C(Cl)=C1 ICUTUKXCWQYESQ-UHFFFAOYSA-N 0.000 description 1
- 229960003500 triclosan Drugs 0.000 description 1
- 125000004385 trihaloalkyl group Chemical group 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000019164 vitamin B2 Nutrition 0.000 description 1
- 239000011716 vitamin B2 Substances 0.000 description 1
- 235000019160 vitamin B3 Nutrition 0.000 description 1
- 239000011708 vitamin B3 Substances 0.000 description 1
- 235000019158 vitamin B6 Nutrition 0.000 description 1
- 239000011726 vitamin B6 Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 150000003700 vitamin C derivatives Chemical class 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 150000003751 zinc Chemical class 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 229940043810 zinc pyrithione Drugs 0.000 description 1
- PICXIOQBANWBIZ-UHFFFAOYSA-N zinc;1-oxidopyridine-2-thione Chemical compound [Zn+2].[O-]N1C=CC=CC1=S.[O-]N1C=CC=CC1=S PICXIOQBANWBIZ-UHFFFAOYSA-N 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
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Landscapes
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- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
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Abstract
Composición que contiene: (A) al menos un agente tensioactivo de N-acil-aminoácido como componente A, estando constituido el componente A por al menos un aminoácido C8-C22-acilado, y seleccionándose el mismo a partir del grupo constituido por glicinato de acilo, aspartato de acilo, glutamato de acilo, sarcosinato de acilo, sus sales y mezclas de los mismos, (B) al menos una N-metil-N-acilglucamina como componente B, (C) al menos un ácido graso C8-C22 o una sal de ácido graso como componente C, (D) al menos un cuerpo oleaginoso como componente D, (E) opcionalmente al menos un isetionato de acilo como componente E, (F) opcionalmente al menos un agente tensioactivo aniónico, sulfonado, como componente F, (G) opcionalmente al menos un agente tensioactivo de betaína como componente G, (H) en caso dado uno o varios aditivos como componente H, y (I) agua.
Description
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(E)
En el ámbito de una forma de realización preferente, la composición según la invención comprende al menos un isetionato de acilo de la fórmula (II) como componente (E):
- R-CO-O-CHR1-CHR2-SO3X
- (II)
- donde
- R
- significa el resto alquilo de un ácido graso C8-C18,
R1 y R2 significan, independientemente entre sí, H o CH3, preferentemente H, y
X es un catión, preferentemente un catión metálico alcalino, en especial Na.
Éste incluye isetionatos de acilo e isetionatos de metil-acilo con un resto C8-C18-acilo y sus mezclas, preferentemente sus sales sódicas. Son especialmente preferentes cocoil isetionatos sódicos y lauroil isetionato sódico.
Muestran una estabilidad especialmente buena las composiciones que contienen también el componente (E).
(F)
En el ámbito de una forma de realización preferente, la composición según la invención comprende al menos un agente tensioactivo aniónico, sulfonado, como componente (F).
En una forma de realización preferente, el componente F se selecciona a partir de uno o varios compuestos de la fórmula general (III)
R1SO3-M+ (III)
representando
R1 alquilo, cicloalquilo, aralquilo, arilo, alcoxi, alcoxialquilo y heterociclilo, y siendo
M+ un ion metálico alcalino, metálico alcalinotérreo, o un ion amonio sustituido o no sustituido, o
de la fórmula general (IV)
-M+
R1SO4 (IV)
representando
R1 alquilo, cicloalquilo, aralquilo, arilo, alcoxi, alcoxialquilo y heterociclilo, y siendo
M+ un ion metálico alcalino, metálico alcalinotérreo, o un ion amonio sustituido o no sustituido.
“Alquilo“ significa un grupo hidrocarburo saturado alifático, que puede ser de cadena lineal o ramificado y puede tener de 1 a 20 átomos de carbono en la cadena. Grupos alquilo preferentes pueden ser de cadena lineal o ramificados y presentar de 1 a 10 átomos de carbono. Ramificado significa que un grupo alquilo inferior, tal como metilo, etilo o propilo, está fijado a una cadena de alquilo lineal. En el caso de alquilo se trata, por ejemplo, de metilo, etilo, 1-propilo, 2-propilo, 1-butilo, 2-butilo, 2-metil-1-propilo (isobutilo), 2-metil-2-propilo (terc-butilo), 1-pentilo, 2pentilo, 3-pentilo, 2-metil-1-butilo, 3-metil-1-butilo, 2-metil-2-butilo, 3-metil-2-butilo, 2,2-dimetil-1-propilo, 1-hexilo, 2hexilo, 3-hexilo, 2-metil-1-pentilo, 3-metil-1-pentilo, 4-metil-1-pentilo, 2-metil-2-pentilo, 3-metil-2-pentilo, 4-metil-2pentilo, 2-metil-3-pentilo, 3-metil-3-pentilo, 2,2-dimetil-1-butilo, 2,3-dimetil-1-butilo, 3,3-dimetil-1-butilo, 2-etil-1-butilo, 2,3-dimetil-2-butilo, 3,3-dimetil-2-butilo, 1-heptilo, 1-octilo, 1-nonilo, 1-decilo, 1-undecilo, 1-dodecilo, 1-tetradecilo, 1hexadecilo y 1-octadecilo.
“Cicloalquilo“ significa un anillo alifático, que tiene de 3 a 10 átomos de carbono en el anillo. Grupos cicloalquilo preferentes tienen de 4 a 7 átomos de carbono en el anillo.
“Arilo“ significa fenilo o naftilo.
“Aralquilo“ significa un grupo alquilo, que está sustituido con un resto arilo.
“Aralquilo sustituido“ y “arilo sustituido“ significan que el grupo arilo o el grupo arilo del grupo aralquilo está sustituido con uno o varios sustituyentes seleccionados a partir de alquilo, alcoxi, nitro, carboalcoxi, ciano, halo, alquilmercaptilo, trihaloalquilo o carboxialquilo.
“Alcoxi“ significa un grupo alquilo-O, en el que “alquilo“ tiene el significado descrito anteriormente. Son preferentes grupos alcoxi inferiores. Son ejemplos metoxi, etoxi, n-propoxi, i-propoxi y n-butoxi.
7
5
10
15
20
25
30
35
40
45
50
La viscosidad deseada de las composiciones se puede ajustar (aumentar o reducir) mediante adición de espesantes y agentes gelificantes. Preferentemente entran en consideración éteres de clulosa y otros derivados de celulosa (por ejemplo carboximetilcelulosa, hidroxietilcelulosa), gelatina, almidón y derivados de almidón, tales como fosfato de hidroxipropil almidón o fosfato de hidroxipropil almidón sódico, alginato sódico, polietilenglicoléster de ácido graso, agar-agar, tragacanto o derivados de dextrina, en especial ésteres de dextrina. Por lo demás son apropiadas amidas de ácido graso; alcanolamidas de ácido graso; dibenzalsorbita y poliamidas y poliacrilamidas solubles en alcohol, o mezclas de tales. Además se pueden usar poliacrilatos reticulados y no reticulados, tales como carbómero, poliacrilato sódico o polímeros que contienen ácido sulfónico, tales como copolímero de acriloildimetiltaurato amónico/VP.
Como agentes sobreengrasantes se pueden usar preferentemente lanolina y lecitina, derivados de lanolina y lecitina no etoxilados y polietoxilados o acilados, ésteres de ácido graso de poliol, mono-, di-y triglicéridos y/o alcanolamidas de ácido graso, así como triglicéridos etoxilados, tales como PEG-7 gliceril cocoato, o mezclas de gliceril oleato con poliglucósidos de alquilo.
En productos activos antimicrobianos se usan cloruro cetiltrimetilamónico, cloruro de cetilpiridinio, cloruro de bencetonio, cloruro diisobutiletoxietildimetilbencilamónico, N-laurilsarcosinato sódico, N-palmetilsarcosinato sódico, lauroilsarcosina, N-miristoilglicina, N-laurilsarcosina potásica, cloruro trimetilamónico, clorohidroxilactato de sodio y aluminio, citrato de trietilo, cloruro tricetilmetilamónico, 2,4,4‘-tricloro-2‘-hidroxidifeniléter (Triclosan), fenoxietanol, 1,5-pentanodiol, 1,6-hexanodiol, 3,4,4‘-triclorocarbanilida (Triclorocarban), diaminoalquilamida, por ejemplo Llisinhexadecilamida, sales de metales pesados de citrato, salicilatos, piroctosas, en especial sales de cinc, piritionas y sus sales de metales pesados, en especial piritiona de cinc, fenolsulfato de cinc, farnesol, ketoconazol, oxiconazol, bifonazoles, butoconazoles, cloconazoles, clotrimazoles, econazoles, enilconazoles, fenticonazoles, isoconazoles, miconazoles, sulconazoles, tioconazoles, fluconazoles, itraconazoles, terconazoles, naftifina y terbinafina, disulfuro de selenio y octopirox, carbamato de yodopropinilbutilo, metilcloroisotiazolinona, metilisotiazolinona, metildibromo glutaronitrilo, AgCl, cloroxilenol, sal de Na de sulfosuccinato de dietilhexilo, benzoato sódico, así como fenoxietanol, alcohol bencílico, fenoxiisopropanol, parabenos, preferentemente butil-, etil-, metil-y propilparabeno, así como sus sales de Na, pentanodiol, 1,2-octanodiol, 2-bromo-2-nitropropano-1,3-diol, etilhexilglicerol, alcohol bencílico, ácido sórbico, ácido benzoico, ácido láctico, imidazolidinilurea, diazolidinilurea, dimetiloldimetilhidantoína (DMDMH), sal de Na glicinato de hidroximetilo, hidroxietilglicina de ácido sórbico, y combinaciones de estas sustancias activas.
Por lo demás, las composiciones según la invención pueden contener productos activos biógenos seleccionados a partir de extractos vegetales, tales como, por ejemplo, Aloe Vera, así como anestésicos locales, antibióticos, antiflogísticos, antialérgicos, corticosteroides, sebostáticos, Bisabolol®, Allantoin®, Phytantriol®, proteínas, vitaminas seleccionadas a partir de niacina, biotina, vitamina B2, vitamina B3, vitamina B6, derivados de vitamina B3 (sales, ácidos, ésteres, amidas, alcoholes), vitamina C y derivados de vitamina C (sales, ácidos, ésteres, amidas, alcoholes), (sales, ácidos, ésteres, amidas, alcoholes), preferentemente como sal sódica de monofosfato de ácido ascórbico o como sal de magnesio de fosfato de ácido ascórbico, tocoferol y acetato de tocoferol, así como vitamina E y/o sus derivados.
Como sustancia humectante se encuentran disponibles, por ejemplo, palmitato de isopropilo, glicerol, diglicerol y/o sorbitol. Es especialmente preferente glicerol.
Como ácidos o lejías para el ajuste del valor de pH se usan preferentemente ácidos minerales, en especial HCl, bases inorgánicas, en especial NaOH o KOH, o ácidos orgánicos, en especial ácido láctico.
Como potenciadores se puede usar preferentemente caprilato de sorbitano.
En el ámbito de una forma de realización preferente, la composición está exenta de sulfatos de alquilo y/o etersulfatos de alquilo. En este caso, exenta significa que la composición contiene menos de 3 % en peso, referido a la cantidad total de composición, preferentemente menos de 0,5 % en peso, y en especial no contiene sulfatos de alquilo y/o etersulfatos de alquilo.
En el ámbito de una forma de realización preferente, en el caso de la composición según la invención se trata de una composición cosmética, dermatológica o farmacéutica.
Otro objeto de la invención es el uso de la composición según la invención como champú, limpiador facial, limpiador líquido o gel de ducha.
Otro objeto de la invención es el uso de la composición según la invención para el tratamiento o cuidado de la piel.
Otro objeto de la invención es el uso de la composición según la invención para el tratamiento o cuidado del cabello.
La invención se explica más detalladamente mediante los siguientes ejemplos.
Los ensayos llevados a cabo muestran también que se obtiene una emulsión estable si están contenidos simultáneamente agente tensioactivo de glicinato y agente tensioactivo de glucamida en la composición. Por el contrario, si se sustituye el agente tensioactivo de glicinato en presencia de glucamidas por lauril etersulfato sódico, no se observan emulsiones estables.
En los ejemplos ulteriores se espesó un gel de ducha oleaginoso con fosfato de hidroxipropil almidón para obtener un buen comportamiento reológico en la aplicación.
- Ejemplo de formulación Componente (%)
- 5 V11
- Agua
- Hasta 100 Hasta 100
- Lauril éter sulfato de Na (2 EO)
- 3 3
- Cocoil glicinato de Na
- 2 2
- Fosfato de hidroxipropil almidón
- 2 2
- Ejemplo de preparación H1
- 2 0
- Ácido láurico
- 1,6 1,6
- Aceite de girasol
- 1,2 1,2
- Perfume de nenúfar
- 1 1
- Cocoil isetionato de Na
- 1 1
- Glicerol
- 1 1
- NaCl
- 1 1
- Ácido esteárico
- 2 2
- Cocamidopropil betaína
- 3 3
- Ácido cítrico
- pH 6,2 pH 6,2
- DMDM hidantoína
- 0,2 0,2
- Viscosidad a 4ºC (mPas)
- 3000 3020
- Viscosidad a 20ºC (mPas)
- 4165 2410
- Viscosidad a 40ºC (mPas)
- 4650 2660
Como se observa en el Ejemplo comparativo 11 y en el Ejemplo 5, la adición de componente B (Ejemplo de preparación 1) a concentración de espesante constante (fosfato de hidroxipropil almidón) conduce a una viscosidad
10 más elevada a 20ºC y 40ºC. Éste es un efecto deseado, ya que, por una parte, para la consecución de la viscosidad objetivo se requiere menos polímero, por otra parte, mediante el mejor perfil de viscosidad se obtienen emulsiones más estables al almacenaje a 40ºC.
Claims (1)
-
imagen1 imagen2 imagen3
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102013006879 | 2013-04-20 | ||
| DE102013006879 | 2013-04-20 | ||
| PCT/EP2014/001022 WO2014170025A1 (de) | 2013-04-20 | 2014-04-16 | Zusammensetzung enthaltend ölkörper, fettsäuren, aminosäuretenside und n-methyl-n-acylglucamine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2640385T3 true ES2640385T3 (es) | 2017-11-02 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14718513.6T Active ES2640385T3 (es) | 2013-04-20 | 2014-04-16 | Composición que contiene cuerpos oleaginosos, ácidos grasos, agentes tensioactivos de aminoácido y N-metil-N-acilglucaminas |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20160074310A1 (es) |
| EP (1) | EP2986345B1 (es) |
| JP (1) | JP6537494B2 (es) |
| CN (1) | CN105263582B (es) |
| BR (1) | BR112015025958B1 (es) |
| ES (1) | ES2640385T3 (es) |
| WO (1) | WO2014170025A1 (es) |
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| BR112014029757A2 (pt) | 2012-05-30 | 2017-06-27 | Clariant Finance Bvi Ltd | composição contendo tensoativos do tipo aminoácido, betaínas e n-metil-n-acilglucaminas e tendo qualidade de espuma melhorada e maior viscosidade |
| CN104582678B (zh) | 2012-05-30 | 2017-05-03 | 科莱恩金融(Bvi)有限公司 | N‑甲基‑n‑酰基葡糖胺在表面活性剂溶液中作为增稠剂的用途 |
| CN104540494B (zh) | 2012-05-30 | 2017-10-24 | 科莱恩金融(Bvi)有限公司 | N‑甲基‑n‑酰基葡糖胺作为增溶剂的用途 |
| WO2013178683A2 (de) | 2012-05-30 | 2013-12-05 | Clariant International Ltd. | N-methyl-n-acylglucamin enthaltende zusammensetzung |
| BR112014029758A2 (pt) | 2012-05-30 | 2017-06-27 | Clariant Finance Bvi Ltd | composição contendo n-metil-n-acilglucamina |
| ES2604840T3 (es) | 2012-05-30 | 2017-03-09 | Clariant International Ltd | Soluciones tensioactivas que contienen N-metil-N-oleil-glucaminas y N-metil-N-(acil de C12-C14)-glucaminas |
| DE102012021647A1 (de) | 2012-11-03 | 2014-05-08 | Clariant International Ltd. | Wässrige Adjuvant-Zusammensetzungen |
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| JP6677636B2 (ja) | 2013-06-28 | 2020-04-08 | クラリアント・インターナシヨナル・リミテツド | 洗髪剤における整髪のための特別なｎ−アルキル−ｎ−アシルグルカミンの使用 |
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-
2014
- 2014-04-16 EP EP14718513.6A patent/EP2986345B1/de not_active Not-in-force
- 2014-04-16 CN CN201480031658.7A patent/CN105263582B/zh not_active Expired - Fee Related
- 2014-04-16 JP JP2016508042A patent/JP6537494B2/ja not_active Expired - Fee Related
- 2014-04-16 WO PCT/EP2014/001022 patent/WO2014170025A1/de not_active Ceased
- 2014-04-16 US US14/785,599 patent/US20160074310A1/en not_active Abandoned
- 2014-04-16 ES ES14718513.6T patent/ES2640385T3/es active Active
- 2014-04-16 BR BR112015025958-8A patent/BR112015025958B1/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN105263582B (zh) | 2018-12-21 |
| EP2986345B1 (de) | 2017-06-14 |
| BR112015025958A2 (pt) | 2017-07-25 |
| WO2014170025A1 (de) | 2014-10-23 |
| CN105263582A (zh) | 2016-01-20 |
| JP2016517852A (ja) | 2016-06-20 |
| EP2986345A1 (de) | 2016-02-24 |
| JP6537494B2 (ja) | 2019-07-03 |
| US20160074310A1 (en) | 2016-03-17 |
| BR112015025958B1 (pt) | 2020-12-08 |
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