ES2528491R1 - Dispositivo para la detección de una única molécula en situación de nanoconfinamiento y en régimen dinámico, procedimiento de fabricación y uso - Google Patents
Dispositivo para la detección de una única molécula en situación de nanoconfinamiento y en régimen dinámico, procedimiento de fabricación y uso Download PDFInfo
- Publication number
- ES2528491R1 ES2528491R1 ES201330922A ES201330922A ES2528491R1 ES 2528491 R1 ES2528491 R1 ES 2528491R1 ES 201330922 A ES201330922 A ES 201330922A ES 201330922 A ES201330922 A ES 201330922A ES 2528491 R1 ES2528491 R1 ES 2528491R1
- Authority
- ES
- Spain
- Prior art keywords
- detection
- situation
- manufacturing
- single molecule
- dynamic regime
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000001514 detection method Methods 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000012141 concentrate Substances 0.000 abstract 1
- 230000005284 excitation Effects 0.000 abstract 1
- 239000002090 nanochannel Substances 0.000 abstract 1
- 239000004038 photonic crystal Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Nanotechnology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Crystallography & Structural Chemistry (AREA)
- Physics & Mathematics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Dispositivo para la detección de una única molécula en situación de nanoconfinamiento y en régimen dinámico, procedimiento de fabricación y uso.#El objeto de la presente invención está relacionado con un dispositivo que integra estructuras de cristal fotónico y micro-nanocanales para la manipulación y detección de moléculas de ADN y otras moléculas con marcadores luminiscentes. El dispositivo, basado en la capacidad de las guías fotónicas de direccionar las ondas electromagnéticas, concentra la señal de emisión de la molécula en respuesta a una señal de excitación en una dirección dada. Son igualmente objetos de la presente invención el procedimiento de fabricación del dispositivo y el uso del mismo para la detección de una única molécula en situación de nanoconfinamiento y en régimen dinámico.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES201330922A ES2528491B1 (es) | 2013-06-20 | 2013-06-20 | Dispositivo para la deteccion de una unica molecula en situacion de nanoconfinamiento y en regimen dinamico, procedimiento de fabricacion y uso |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES201330922A ES2528491B1 (es) | 2013-06-20 | 2013-06-20 | Dispositivo para la deteccion de una unica molecula en situacion de nanoconfinamiento y en regimen dinamico, procedimiento de fabricacion y uso |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ES2528491A2 ES2528491A2 (es) | 2015-02-10 |
| ES2528491R1 true ES2528491R1 (es) | 2015-02-24 |
| ES2528491B1 ES2528491B1 (es) | 2020-02-27 |
Family
ID=52446007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES201330922A Withdrawn - After Issue ES2528491B1 (es) | 2013-06-20 | 2013-06-20 | Dispositivo para la deteccion de una unica molecula en situacion de nanoconfinamiento y en regimen dinamico, procedimiento de fabricacion y uso |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2528491B1 (es) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060166223A1 (en) * | 2005-01-26 | 2006-07-27 | Reed Michael W | DNA purification and analysis on nanoengineered surfaces |
| WO2009055903A1 (en) * | 2007-10-29 | 2009-05-07 | National Research Council Of Canada | Method and apparatus for detecting fluorescence emitted by particle-bound fluorophores confined by particle traps |
| WO2009150583A1 (en) * | 2008-06-10 | 2009-12-17 | Koninklijke Philips Electronics N.V. | Diagnostic device |
| US20120007000A1 (en) * | 2010-07-08 | 2012-01-12 | The Board of Trustees of the University of Illinois SRU Biosystems, Inc. | Multi-color fluorescence enhancement from a photonic crystal surface |
-
2013
- 2013-06-20 ES ES201330922A patent/ES2528491B1/es not_active Withdrawn - After Issue
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060166223A1 (en) * | 2005-01-26 | 2006-07-27 | Reed Michael W | DNA purification and analysis on nanoengineered surfaces |
| WO2009055903A1 (en) * | 2007-10-29 | 2009-05-07 | National Research Council Of Canada | Method and apparatus for detecting fluorescence emitted by particle-bound fluorophores confined by particle traps |
| WO2009150583A1 (en) * | 2008-06-10 | 2009-12-17 | Koninklijke Philips Electronics N.V. | Diagnostic device |
| US20120007000A1 (en) * | 2010-07-08 | 2012-01-12 | The Board of Trustees of the University of Illinois SRU Biosystems, Inc. | Multi-color fluorescence enhancement from a photonic crystal surface |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2528491A2 (es) | 2015-02-10 |
| ES2528491B1 (es) | 2020-02-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
Ref document number: 2528491 Country of ref document: ES Kind code of ref document: B1 Effective date: 20200227 |
|
| FA2A | Application withdrawn |
Effective date: 20200701 |