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ES2430553T3 - Análisis de resistencia a fármacos de tipo equinocandinas - Google Patents

Análisis de resistencia a fármacos de tipo equinocandinas Download PDF

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Publication number
ES2430553T3
ES2430553T3 ES06788713T ES06788713T ES2430553T3 ES 2430553 T3 ES2430553 T3 ES 2430553T3 ES 06788713 T ES06788713 T ES 06788713T ES 06788713 T ES06788713 T ES 06788713T ES 2430553 T3 ES2430553 T3 ES 2430553T3
Authority
ES
Spain
Prior art keywords
probes
cafks1
sequence
mutations
target sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES06788713T
Other languages
English (en)
Spanish (es)
Inventor
David S. Perlin
Steven Park
Cameron M. Douglas
Jennifer Nielsen Kahn
Stephen A. Parent
Rosemarie Kelly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon Pharma UK Ltd
Rutgers State University of New Jersey
Merck Sharp and Dohme LLC
Rutgers Health
Original Assignee
Merck Sharp and Dohme Ltd
University of Medicine and Dentistry of New Jersey
Rutgers State University of New Jersey
Merck Sharp and Dohme LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme Ltd, University of Medicine and Dentistry of New Jersey, Rutgers State University of New Jersey, Merck Sharp and Dohme LLC filed Critical Merck Sharp and Dohme Ltd
Application granted granted Critical
Publication of ES2430553T3 publication Critical patent/ES2430553T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Chemical Kinetics & Catalysis (AREA)
ES06788713T 2005-07-26 2006-07-26 Análisis de resistencia a fármacos de tipo equinocandinas Active ES2430553T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70275605P 2005-07-26 2005-07-26
US702756P 2005-07-26
PCT/US2006/029290 WO2007014305A2 (fr) 2005-07-26 2006-07-26 Analyses determinant la resistance a des medicaments de la classe des echinocandines

Publications (1)

Publication Number Publication Date
ES2430553T3 true ES2430553T3 (es) 2013-11-21

Family

ID=37683977

Family Applications (1)

Application Number Title Priority Date Filing Date
ES06788713T Active ES2430553T3 (es) 2005-07-26 2006-07-26 Análisis de resistencia a fármacos de tipo equinocandinas

Country Status (11)

Country Link
US (3) US8753819B2 (fr)
EP (1) EP1907588B1 (fr)
JP (1) JP5319281B2 (fr)
CN (1) CN101448953B (fr)
AU (1) AU2006272568B2 (fr)
BR (1) BRPI0614445B8 (fr)
CA (1) CA2617063C (fr)
ES (1) ES2430553T3 (fr)
IL (1) IL189013A (fr)
PT (1) PT1907588E (fr)
WO (1) WO2007014305A2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007014305A2 (fr) * 2005-07-26 2007-02-01 University Of Medicine And Dentistry Of New Jersey Analyses determinant la resistance a des medicaments de la classe des echinocandines
AU2009246363B2 (en) 2008-05-13 2013-10-24 Gen-Probe Incorporated Inactivatable target capture oligomers for use in the selective hybridization and capture of target nucleic acid sequences
SI2680873T1 (sl) 2011-03-03 2017-12-29 Cidara Therapeutics, Inc. Protiglivna sredstva in njihova uporaba
EP3677252B1 (fr) 2012-03-19 2023-06-28 Cidara Therapeutics, Inc. Schémas posologiques pour composés de la classe des échinocandines
US9920385B2 (en) 2014-10-09 2018-03-20 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Detection of echinocandin-resistant Candida glabrata
US20180256673A1 (en) * 2015-09-16 2018-09-13 Cidara Therapeutics, Inc. Methods for treating fungal infections
US10369188B2 (en) 2016-01-08 2019-08-06 Cidara Therapeutics, Inc. Methods for preventing and treating pneumocystis infections
JP7224916B2 (ja) 2016-03-16 2023-02-20 シダラ セラピューティクス インコーポレーテッド 真菌感染の処置のための投薬レジメン
US11197909B2 (en) 2017-07-12 2021-12-14 Cidara Therapeutics, Inc. Compositions and methods for the treatment of fungal infections
CA3111751A1 (fr) 2018-09-03 2020-03-12 Visby Medical, Inc. Dispositifs et procedes d'essai de susceptibilite aux antibiotiques
EP4085149A4 (fr) 2020-01-03 2024-03-06 Visby Medical, Inc. Dispositifs et procédés d'essai de susceptibilité aux antibiotiques
CN113249452A (zh) * 2021-07-05 2021-08-13 丹娜(天津)生物科技股份有限公司 一种检测白念珠菌棘白菌素类耐药突变靶点的引物探针组合及其应用
CN114958901B (zh) * 2022-05-24 2024-06-04 华中科技大学 一种抗真菌药物作用靶点的体外制备、活性检测及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
JP3664490B2 (ja) * 1993-10-12 2005-06-29 メルク エンド カムパニー インコーポレーテッド 1,3−β−Dグルカンシンターゼ・サブユニットをコードするDNA
US5925517A (en) 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
US5538848A (en) 1994-11-16 1996-07-23 Applied Biosystems Division, Perkin-Elmer Corp. Method for detecting nucleic acid amplification using self-quenching fluorescence probe
EP0931834A3 (fr) * 1997-12-23 2002-06-26 Eli Lilly And Company Domaine de liaison d'echinocandinl de la 1,3-beta-glucane synthase
US20030180953A1 (en) * 2000-12-29 2003-09-25 Elitra Pharmaceuticals, Inc. Gene disruption methodologies for drug target discovery
US7198897B2 (en) 2001-12-19 2007-04-03 Brandeis University Late-PCR
WO2007014305A2 (fr) * 2005-07-26 2007-02-01 University Of Medicine And Dentistry Of New Jersey Analyses determinant la resistance a des medicaments de la classe des echinocandines
CA2746539A1 (fr) * 2008-12-30 2010-07-08 Gen-Probe Incorporated Composition, kits et methodes correspondantes pour la detection et/ou la surveillance de listeria

Also Published As

Publication number Publication date
WO2007014305A2 (fr) 2007-02-01
EP1907588A4 (fr) 2009-11-04
BRPI0614445A2 (pt) 2011-03-29
JP5319281B2 (ja) 2013-10-16
CA2617063C (fr) 2015-04-14
EP1907588A2 (fr) 2008-04-09
CN101448953A (zh) 2009-06-03
BRPI0614445B8 (pt) 2021-07-27
CA2617063A1 (fr) 2007-02-01
AU2006272568A8 (en) 2008-04-24
AU2006272568A1 (en) 2007-02-01
EP1907588B1 (fr) 2013-06-05
US10934577B2 (en) 2021-03-02
IL189013A0 (en) 2008-08-07
BRPI0614445B1 (pt) 2018-11-06
US20150125856A1 (en) 2015-05-07
WO2007014305A3 (fr) 2007-09-13
CN101448953B (zh) 2014-05-07
PT1907588E (pt) 2013-10-09
US20100075302A1 (en) 2010-03-25
US9657334B2 (en) 2017-05-23
US20170356034A1 (en) 2017-12-14
IL189013A (en) 2014-11-30
US8753819B2 (en) 2014-06-17
AU2006272568B2 (en) 2012-06-28
JP2009502174A (ja) 2009-01-29

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