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ES2307351B2 - Cepa viva atenuada de staphylococcus aureus como vacuna en mastitis de rumiantes. - Google Patents

Cepa viva atenuada de staphylococcus aureus como vacuna en mastitis de rumiantes. Download PDF

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Publication number
ES2307351B2
ES2307351B2 ES200500809A ES200500809A ES2307351B2 ES 2307351 B2 ES2307351 B2 ES 2307351B2 ES 200500809 A ES200500809 A ES 200500809A ES 200500809 A ES200500809 A ES 200500809A ES 2307351 B2 ES2307351 B2 ES 2307351B2
Authority
ES
Spain
Prior art keywords
strain
staphylococcus aureus
aureus
baselineskip
live
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES200500809A
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English (en)
Spanish (es)
Other versions
ES2307351A1 (es
Inventor
Ricardo De La Fuente Lopez
Gustavo Dominguez Bernal
Jose Antonio Orden Gutierrez
Susana Martinez Pulgarin
Jose Antonio Ruiz Santa-Quiteria
Dolores Cid Vazquez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad Complutense de Madrid
Original Assignee
Universidad Complutense de Madrid
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad Complutense de Madrid filed Critical Universidad Complutense de Madrid
Priority to ES200500809A priority Critical patent/ES2307351B2/es
Priority to PCT/ES2006/000164 priority patent/WO2006106166A1/fr
Publication of ES2307351A1 publication Critical patent/ES2307351A1/es
Application granted granted Critical
Publication of ES2307351B2 publication Critical patent/ES2307351B2/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0065Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/085Staphylococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36Adaptation or attenuation of cells
    • C12R1/445
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y111/00Oxidoreductases acting on a peroxide as acceptor (1.11)
    • C12Y111/01Peroxidases (1.11.1)
    • C12Y111/01006Catalase (1.11.1.6)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/44Staphylococcus
    • C12R2001/445Staphylococcus aureus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ES200500809A 2005-04-07 2005-04-07 Cepa viva atenuada de staphylococcus aureus como vacuna en mastitis de rumiantes. Expired - Fee Related ES2307351B2 (es)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ES200500809A ES2307351B2 (es) 2005-04-07 2005-04-07 Cepa viva atenuada de staphylococcus aureus como vacuna en mastitis de rumiantes.
PCT/ES2006/000164 WO2006106166A1 (fr) 2005-04-07 2006-04-06 Souche vive attenuee de staphylococcus aureus servant de vaccin contre la mammite bovine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200500809A ES2307351B2 (es) 2005-04-07 2005-04-07 Cepa viva atenuada de staphylococcus aureus como vacuna en mastitis de rumiantes.

Publications (2)

Publication Number Publication Date
ES2307351A1 ES2307351A1 (es) 2008-11-16
ES2307351B2 true ES2307351B2 (es) 2009-06-17

Family

ID=37073109

Family Applications (1)

Application Number Title Priority Date Filing Date
ES200500809A Expired - Fee Related ES2307351B2 (es) 2005-04-07 2005-04-07 Cepa viva atenuada de staphylococcus aureus como vacuna en mastitis de rumiantes.

Country Status (2)

Country Link
ES (1) ES2307351B2 (fr)
WO (1) WO2006106166A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011027956A2 (fr) * 2009-09-04 2011-03-10 주식회사이언메딕스 Vésicules extracellulaires issues de bactéries à gram positif, et modèle de maladie utilisant celles-ci

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BRAMLEY, A. J., PATEL, A. H., O'REILLY, M. et al. Roles of alpha- toxin and beta-toxin in virulence of Staphylococcus aureus for the mouse mammary gland. Infection and Immunity. Agosto 1989, Vol. 57, N$^{o}$ 8, páginas 2489-2494. ISSN 0019-9567. *
COLEMAN, D., KNIGHTS, J., RUSSELL, R. et al. Insertional inactivation of the Staphylococcus aureus beta-toxin by bacteriophage phi-13 occurs by site- and orientation-specific integration of the phi-13 genome. Molecular Microbiology. 1991, Vol. 5, N$^{o}$ 4, páginas 933-939. ISSN 0950-382X. *
ODIERNO, L., RISATTI, G., CALZOLARI, A. et al. Pathogenicity in mice of Staphylococcus aureus mutants deficient in exoprotein synthesis. Veterinary Microbiology. Agosto 1994, Vol. 41, N$^{o}$ 3 páginas 249-258. ISSN 0378-1135. *
SANZ, R., MARÍN, I., RUIZ-SANTA-QUITERIA, J. A. et al. Catalase deficiency in Staphylococcus aureus subsp. anaerobius is associated with natural loss-of-function mutations within the structural gene. Microbiology. Febrero 2000, Vol. 146, N$^{o}$ 2, páginas 465-475. ISSN 1350-0872. *

Also Published As

Publication number Publication date
WO2006106166A1 (fr) 2006-10-12
ES2307351A1 (es) 2008-11-16

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