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ES2349838A8 - Derivados de pirazol bivalentes como inhibidores de ingesta. - Google Patents

Derivados de pirazol bivalentes como inhibidores de ingesta. Download PDF

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Publication number
ES2349838A8
ES2349838A8 ES200930120A ES200930120A ES2349838A8 ES 2349838 A8 ES2349838 A8 ES 2349838A8 ES 200930120 A ES200930120 A ES 200930120A ES 200930120 A ES200930120 A ES 200930120A ES 2349838 A8 ES2349838 A8 ES 2349838A8
Authority
ES
Spain
Prior art keywords
bivalent
derivatives
inhibitors
ingestion inhibitors
pirazol derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES200930120A
Other languages
English (en)
Other versions
ES2349838B1 (es
ES2349838A1 (es
Inventor
Fernando Rodriguez de Fonseca
Nadine Jagerovic
Cristina Fernandez Fernandez
Francisco Javie Bermudez Silva
Maria Pilar Goya Laza
Miguel Romero Cuevas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consejo Superior de Investigaciones Cientificas CSIC
Instituto Mediterraneo para el Avance de la Biotecnologia y la Investigacion Sanitaria (Fundacion Imabis)
Original Assignee
Consejo Superior de Investigaciones Cientificas CSIC
Instituto Mediterraneo para el Avance de la Biotecnologia y la Investigacion Sanitaria (Fundacion Imabis)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consejo Superior de Investigaciones Cientificas CSIC, Instituto Mediterraneo para el Avance de la Biotecnologia y la Investigacion Sanitaria (Fundacion Imabis) filed Critical Consejo Superior de Investigaciones Cientificas CSIC
Priority to ES200930120A priority Critical patent/ES2349838B1/es
Priority to PCT/ES2010/070293 priority patent/WO2010128191A1/es
Publication of ES2349838A1 publication Critical patent/ES2349838A1/es
Publication of ES2349838A8 publication Critical patent/ES2349838A8/es
Application granted granted Critical
Publication of ES2349838B1 publication Critical patent/ES2349838B1/es
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Derivados de pirazol bivalentes como inhibidores de ingesta.
Nuevos derivados alquílicos y cicloalquílicos disustituidos por pirazol-3-carboxamidas, así como su procedimiento de obtención. Estos compuestos presentan propiedades, entre otras, para la inducción de saciedad y control de la ingesta, modulación de la grasa corporal y regulación del metabolismo lipídico.
ES200930120A 2009-05-04 2009-05-04 Derivados de pirazol bivalentes como inhibidores de ingesta Expired - Fee Related ES2349838B1 (es)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ES200930120A ES2349838B1 (es) 2009-05-04 2009-05-04 Derivados de pirazol bivalentes como inhibidores de ingesta
PCT/ES2010/070293 WO2010128191A1 (es) 2009-05-04 2010-05-04 Derivados de pirazol bivalentes como inhibidores de ingesta

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200930120A ES2349838B1 (es) 2009-05-04 2009-05-04 Derivados de pirazol bivalentes como inhibidores de ingesta

Publications (3)

Publication Number Publication Date
ES2349838A1 ES2349838A1 (es) 2011-01-11
ES2349838A8 true ES2349838A8 (es) 2011-04-26
ES2349838B1 ES2349838B1 (es) 2011-11-15

Family

ID=43050020

Family Applications (1)

Application Number Title Priority Date Filing Date
ES200930120A Expired - Fee Related ES2349838B1 (es) 2009-05-04 2009-05-04 Derivados de pirazol bivalentes como inhibidores de ingesta

Country Status (2)

Country Link
ES (1) ES2349838B1 (es)
WO (1) WO2010128191A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113956297B (zh) * 2021-11-18 2023-12-29 江苏科技大学 Co(III)-Co(II)双核钴单分子磁体及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2861303A1 (fr) * 2003-10-24 2005-04-29 Sanofi Synthelabo Utilisation d'un derive de pyrazole pour la preparation de medicaments utiles dans la prevention et le traitement du syndrome metabolique
EP1993560B1 (en) * 2006-03-10 2011-12-28 Jenrin Discovery Cannabinoid receptor antagonists/inverse agonists useful for treating obesity

Also Published As

Publication number Publication date
ES2349838B1 (es) 2011-11-15
WO2010128191A1 (es) 2010-11-11
ES2349838A1 (es) 2011-01-11

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