ES2222818A1 - Lactic acid emulsion for e.g. skin regeneration comprises a starch derivative and hydrating oils product - Google Patents
Lactic acid emulsion for e.g. skin regeneration comprises a starch derivative and hydrating oils productInfo
- Publication number
- ES2222818A1 ES2222818A1 ES200301761A ES200301761A ES2222818A1 ES 2222818 A1 ES2222818 A1 ES 2222818A1 ES 200301761 A ES200301761 A ES 200301761A ES 200301761 A ES200301761 A ES 200301761A ES 2222818 A1 ES2222818 A1 ES 2222818A1
- Authority
- ES
- Spain
- Prior art keywords
- lactic acid
- proportion
- emulsion
- acid emulsion
- starch
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 title claims abstract description 66
- 235000014655 lactic acid Nutrition 0.000 title claims abstract description 33
- 239000004310 lactic acid Substances 0.000 title claims abstract description 33
- 239000000839 emulsion Substances 0.000 title claims abstract description 26
- 239000003921 oil Substances 0.000 title claims abstract description 11
- 230000000887 hydrating effect Effects 0.000 title abstract description 3
- 229920000881 Modified starch Polymers 0.000 title abstract 2
- 235000019426 modified starch Nutrition 0.000 title abstract 2
- 230000036560 skin regeneration Effects 0.000 title abstract 2
- 230000036571 hydration Effects 0.000 claims abstract description 6
- 238000006703 hydration reaction Methods 0.000 claims abstract description 6
- 229920002472 Starch Polymers 0.000 claims description 10
- 239000003381 stabilizer Substances 0.000 claims description 10
- 239000008107 starch Substances 0.000 claims description 10
- 235000019698 starch Nutrition 0.000 claims description 10
- 239000000203 mixture Substances 0.000 claims description 9
- 239000004251 Ammonium lactate Substances 0.000 claims description 7
- 229940059265 ammonium lactate Drugs 0.000 claims description 7
- 235000019286 ammonium lactate Nutrition 0.000 claims description 7
- RZOBLYBZQXQGFY-HSHFZTNMSA-N azanium;(2r)-2-hydroxypropanoate Chemical compound [NH4+].C[C@@H](O)C([O-])=O RZOBLYBZQXQGFY-HSHFZTNMSA-N 0.000 claims description 7
- 229920002678 cellulose Polymers 0.000 claims description 6
- 230000000295 complement effect Effects 0.000 claims description 6
- 229910019142 PO4 Inorganic materials 0.000 claims description 3
- 239000010452 phosphate Substances 0.000 claims description 3
- 230000008929 regeneration Effects 0.000 claims description 2
- 238000011069 regeneration method Methods 0.000 claims description 2
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 claims 2
- 238000010521 absorption reaction Methods 0.000 claims 2
- 235000010980 cellulose Nutrition 0.000 claims 2
- -1 ester phosphate Chemical class 0.000 claims 2
- 229940057995 liquid paraffin Drugs 0.000 claims 2
- 150000003626 triacylglycerols Chemical class 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 abstract description 8
- 239000002253 acid Substances 0.000 abstract description 4
- 210000003491 skin Anatomy 0.000 description 9
- 230000008901 benefit Effects 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
- 239000006071 cream Substances 0.000 description 5
- 230000035515 penetration Effects 0.000 description 5
- 239000001913 cellulose Substances 0.000 description 4
- 230000003020 moisturizing effect Effects 0.000 description 4
- 210000002615 epidermis Anatomy 0.000 description 2
- 238000010348 incorporation Methods 0.000 description 2
- 230000001172 regenerating effect Effects 0.000 description 2
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000008346 aqueous phase Substances 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 230000037368 penetrate the skin Effects 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Emulsión de ácido láctico.Lactic acid emulsion.
La presente memoria descriptiva se refiere, como su título indica, a una emulsión de ácido láctico, del tipo de las utilizadas principalmente para la hidratación y regeneración de la piel, caracterizada porque utiliza un estabilizador derivado del almidón para conseguir un Ph muy bajo, y por tanto una concentración muy ácida, de una manera estable y duradera, complementándola con una mezcla de varios aceites hidratantes de diversas características que permiten la hidratación a diferentes niveles cutáneos.The present specification refers to, as its title indicates, to an emulsion of lactic acid, of the type of mainly used for hydration and regeneration of the skin, characterized in that it uses a stabilizer derived from starch to get a very low Ph, and therefore a very acid concentration, in a stable and lasting way, complementing it with a mixture of several moisturizing oils of various features that allow hydration to different skin levels
En la actualidad está plenamente conocido y testado clínicamente el efecto terapéutico y cosmético del ácido láctico. Entre sus principales efectos beneficiosos podemos citar la excelente hidratación y los efectos regenerativos que presenta en la piel, ayudando a compensar los efectos del deterioro de la piel causado por los agentes externos o por la edad. También ha sido testado ampliamente que la eficacia terapéutica del ácido láctico se incrementa enormemente con la acidez de la concentración, a mayor acidez (menor Ph) se produce un mayor efecto hidratante y regenerativo sobre la piel. Por ello el ácido láctico es comúnmente utilizado en cremas, geles, jabones y diversos tipos de emulsiones disponibles comercialmente en el mercado. Sin embargo, la naturaleza ácida inherente al ácido láctico hace que todas estas emulsiones sean bastante inestables y de corta duración, por lo que la concentración de ácido láctico no suele ser muy elevada, siendo comunes en el mercado emulsiones y cremas con un Ph relativamente alto, de 5.5 o incluso superior, es decir con una acidez relativamente baja, con lo que los efectos terapéuticos se ven bastante atenuados. En caso de intentar realizar cremas con una acidez mayor, y por tanto con una eficacia terapéutica superior, han sido comunes los problemas de estabilidad de las cremas, descomposición a corto plazo e incluso mal olor, lo cual ha afectado negativamente en su comercialización.He is currently fully known and clinically tested the therapeutic and cosmetic effect of acid lactic. Among its main beneficial effects we can mention the excellent hydration and regenerative effects it presents on the skin, helping to compensate for the effects of the deterioration of the skin caused by external agents or by age. Too a been extensively tested that the therapeutic efficacy of acid lactic acid increases greatly with the acidity of the concentration, higher acidity (lower Ph) produces a greater moisturizing effect and regenerative on the skin. This is why lactic acid is commonly Used in creams, gels, soaps and various types of emulsions commercially available in the market. However, the acidic nature inherent in lactic acid makes all these emulsions are quite unstable and short-lived, so The concentration of lactic acid is usually not very high, being common emulsions and creams in the market with a relatively Ph high, 5.5 or even higher, that is with acidity relatively low, so the therapeutic effects are seen Pretty dimmed. If you try to make creams with a higher acidity, and therefore with superior therapeutic efficacy, cream stability problems have been common, short-term decomposition and even bad smell, which has negatively affected in its commercialization.
Para solventar la problemática existente en la actualidad en cuanto al problema de acidez en las emulsiones de todo tipo que utilizan el ácido láctico en su composición se ha ideado la emulsión de ácido láctico objeto de la presente invención, la cual presenta como gran novedad la incorporación en su composición de un estabilizador derivado del almidón, o de otro tipo de celulosas, que permite conseguir una alta acidez en la concentración de ácido láctico, típicamente con un Ph comprendido entre 2.2 y 4.5, preferentemente entre 3 y 3.5, sin los inconvenientes inherentes a su alta acidez, pero manteniendo todas las ventajas terapéuticas originadas por su alta concentración.To solve the problem in the news regarding the acidity problem in emulsions of all types that use lactic acid in their composition have devised the emulsion of lactic acid object of the present invention, which presents as a great novelty the incorporation into its composition of a stabilizer derived from starch, or other cellulose type, which allows to achieve high acidity in the lactic acid concentration, typically with a Ph included between 2.2 and 4.5, preferably between 3 and 3.5, without the inconveniences inherent to its high acidity, but maintaining all The therapeutic advantages caused by its high concentration.
La emulsión se complementa con una combinación de varios aceites de diversas polaridades, preferentemente 3, que complementan sus efectos hidratantes con los del ácido láctico para obtener un efecto más potenciado. Uno de los aceites es del tipo no polar, con lo cual su penetración en la piel es alta, de manera similar a la del ácido láctico, efectuando por tanto sus efectos en las capas más profundas de la epidermis de manera complementaria al ácido láctico. Otro de los aceites es de una penetración intermedia y propicia un intenso efecto hidratante en las capas intermedias de la piel. Por último, otro de los aceites es del tipo polar, con lo que no penetra en la piel, quedando en su superficie, hidratándola, protegiéndola y creando un efecto barrera que impide que el resto de los componentes de la emulsión que han penetrado en las capas interiores de la epidermis se evaporen fácilmente, consiguiendo que estos componentes potencien su efecto durante un tiempo mayor.The emulsion is complemented by a combination of several oils of various polarities, preferably 3, which complement its moisturizing effects with those of lactic acid to Get a more enhanced effect. One of the oils is of type no polar, so that your skin penetration is high, so similar to that of lactic acid, thus effecting its effects on the deeper layers of the epidermis in a complementary way to the lactic acid. Another oil is an intermediate penetration and promotes an intense moisturizing effect in the intermediate layers of the skin. Finally, another of the oils is of the polar type, with what that does not penetrate the skin, remaining on its surface, hydrating it, protecting it and creating a barrier effect that prevents the rest of the emulsion components that have penetrated the layers The interiors of the epidermis evaporate easily, getting These components enhance their effect for a longer time.
Esta emulsión de ácido láctico que se presenta aporta múltiples ventajas sobre los productos disponibles en la actualidad para la misma aplicación, siendo la más importante que, debido a utilizar un estabilizante derivado del almidón o de otras celulosas, la acidez conseguida es muy alta, y por tanto el efecto terapéutico del ácido láctico se ve potenciado enormemente.This lactic acid emulsion that comes provides multiple advantages over the products available in the actuality for the same application, being the most important that, due to using a stabilizer derived from starch or other cellulose, the acidity achieved is very high, and therefore the effect Lactic acid therapeutic is greatly enhanced.
Otra ventaja que se consigue es que el estabilizante obtiene una mayor duración de la emulsión, mejorando su estabilidad a largo plazo.Another advantage that is achieved is that the stabilizer obtains a longer duration of the emulsion, improving Its long-term stability.
También hay que destacar la gran ventaja que produce la mezcla de aceites complementarios, ya que se consigue una completa hidratación de todas las capas cutáneas a diferentes niveles.We must also highlight the great advantage that produces the mixture of complementary oils, since it is achieved a complete hydration of all skin layers to different levels.
Como consecuencia de lo anterior, esta invención presenta la enorme ventaja de su mejor comercialización y aceptación por el usuario, que redunda en un beneficio económico mayor.As a consequence of the foregoing, this invention it presents the enormous advantage of its best commercialization and user acceptance, which results in an economic benefit higher.
Como ya hemos visto anteriormente, la emulsión de ácido láctico objeto de la presente invención, presenta como gran novedad la incorporación en su composición de un estabilizador derivado del almidón, o de otro tipo de celulosas, que es el elemento que permite conseguir una alta acidez en la concentración de ácido láctico. Para ello la emulsión estará formada, entre otros elementos, por una combinación deAs we have seen before, the emulsion of lactic acid object of the present invention, presents as great novelty the incorporation in its composition of a stabilizer derived from starch, or other cellulose, which is the element that allows to achieve a high acidity in the concentration of lactic acid. For this, the emulsion will be formed, among others elements, for a combination of
- \bullet?
- Ácido láctico - en una proporción comprendida entre el 1% y el 10%. Lactic acid - in a proportion between 1% and 10%.
- \bullet?
- Lactato amónico - en una proporción comprendida entre el 0.3% y el 3%. Ammonium lactate - in a proportion between 0.3% and 3%.
El lactato amónico y el ácido láctico deberán estar siempre en una relación aproximada de 1:3, es decir, el porcentaje de ácido láctico será siempre de tres veces el del lactato amónico para poder así conseguir el Ph bajo deseado.Ammonium lactate and lactic acid should always be in an approximate ratio of 1: 3, that is, the Lactic acid percentage will always be three times that of Ammonium lactate in order to achieve the desired low Ph.
A esta combinación se la añade el estabilizador derivado del almidón, o de otro tipo de celulosas, que preferentemente será:To this combination is added the stabilizer derived from starch, or other cellulose, which preferably it will be:
- \bullet?
- Ester fosfato de almidón hidroxipropilado - en una proporción comprendida entre el 1% y el 6%.Ester hydroxypropylated starch phosphate - in a proportion comprised between 1% and 6%.
Como ya hemos citado anteriormente, también se incluyen en la emulsión tres aceites, de efecto complementario, que preferentemente serán:As we have already mentioned above, it is also they include in the emulsion three oils, of complementary effect, that preferably they will be:
- \bullet?
- Parafina liquida - (baja penetración) - en una proporción comprendida entre el 2% y el 10%.Paraffin liquid - (low penetration) - in a proportion between 2% and 10%.
- \bullet?
- Triglicérido caprílico / cáprico - (penetración media) - en una proporción entre el 2% y el 5%.Triglyceride caprylic / capric - (medium penetration) - in a proportion between 2% and 5%.
- \bullet?
- Miristato de isopropilo - (alta penetración) - en una proporción entre el 2% y el 5%.Myristat of isopropyl - (high penetration) - in a proportion between 2% and 5%
La combinación de todos estos elementos permite obtener una emulsión con un Ph comprendido entre 2.2 y 4.5, preferentemente entre 3 y 3.5, sin los inconvenientes inherentes a su alta acidez, pero manteniendo todas las ventajas terapéuticas originadas por su alta concentración.The combination of all these elements allows obtain an emulsion with a Ph between 2.2 and 4.5, preferably between 3 and 3.5, without the inconveniences inherent in its high acidity, but maintaining all the therapeutic advantages originated by its high concentration.
Por supuesto, la emulsión incorporará además los componentes habituales en todo tipo de cremas y productos para la piel, ampliamente conocidos y utilizados, como emulgente espesante en fase acuosa, conservantes, colorantes, etc... y que no son objeto de reivindicación ninguna.Of course, the emulsion will also incorporate the usual components in all types of creams and products for skin, widely known and used, as a thickener emulsifier in the aqueous phase, preservatives, dyes, etc ... and that are not claim none.
Se omite voluntariamente hacer una descripción detallada del resto de particularidades del producto que se presenta, de su método de fabricación o de los elementos componentes que lo integran, pues estimamos por nuestra parte que el resto de dichas particularidades no son objeto de reivindicación alguna.A description is voluntarily omitted detailed of the rest of particularities of the product that presents, of its manufacturing method or of the elements components that integrate it, because we believe that the rest of said particularities are not subject to claim any.
Una vez descrita suficientemente la naturaleza de la presente invención, así como una forma de llevarlo a la práctica, solo nos queda por añadir que su descripción no es limitativa, pudiéndose efectuar algunas variaciones, tanto en materiales como en formas o tamaños, siempre y cuando dichas variaciones no alteren la esencialidad de las características que se reivindican a continuación.Once the nature of the present invention, as well as a way of bringing it to the practice, we just have to add that its description is not limiting, being able to make some variations, both in materials as in shapes or sizes, as long as said variations do not alter the essentiality of the characteristics that They are claimed below.
Claims (6)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200301761A ES2222818B1 (en) | 2003-07-25 | 2003-07-25 | EMULSION OF LACTIC ACID. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200301761A ES2222818B1 (en) | 2003-07-25 | 2003-07-25 | EMULSION OF LACTIC ACID. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2222818A1 true ES2222818A1 (en) | 2005-02-01 |
| ES2222818B1 ES2222818B1 (en) | 2007-03-01 |
Family
ID=34354828
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES200301761A Expired - Fee Related ES2222818B1 (en) | 2003-07-25 | 2003-07-25 | EMULSION OF LACTIC ACID. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2222818B1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018237218A1 (en) | 2017-06-23 | 2018-12-27 | The Procter & Gamble Company | COMPOSITION AND METHOD FOR ENHANCING SKIN APPEARANCE |
| EP3817717A1 (en) | 2018-07-03 | 2021-05-12 | The Procter & Gamble Company | Method of treating a skin condition |
| JP7590462B2 (en) | 2020-06-01 | 2024-11-26 | ザ プロクター アンド ギャンブル カンパニー | Method for improving skin penetration of vitamin B3 compounds |
| US10959933B1 (en) | 2020-06-01 | 2021-03-30 | The Procter & Gamble Company | Low pH skin care composition and methods of using the same |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4234599A (en) * | 1978-10-04 | 1980-11-18 | Scott Eugene J Van | Treatment of skin keratoses with α-hydroxy acids and related compounds |
| EP0423929A1 (en) * | 1989-09-20 | 1991-04-24 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Skin whitening agent |
| FR2720643A1 (en) * | 1994-06-03 | 1995-12-08 | Clarins | Cosmetic compsn. contg. mixt. of hydroxy-acids |
| US5561166A (en) * | 1993-07-28 | 1996-10-01 | Beiersdorf, Inc. | Urea/lactate topical compositions for dry skin |
| US5569651A (en) * | 1995-03-03 | 1996-10-29 | Avon Products, Inc. | Gentle anti-acne composition |
| ES2123910T3 (en) * | 1994-03-22 | 1999-01-16 | Bristol Myers Squibb Co | COMPOSITIONS CONTAINING AMPHOTERAL SALTS OF ALPHA-HYDROXIACIDES AND GLYCEROL MONOCAPRILATE. |
-
2003
- 2003-07-25 ES ES200301761A patent/ES2222818B1/en not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4234599A (en) * | 1978-10-04 | 1980-11-18 | Scott Eugene J Van | Treatment of skin keratoses with α-hydroxy acids and related compounds |
| EP0423929A1 (en) * | 1989-09-20 | 1991-04-24 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Skin whitening agent |
| US5561166A (en) * | 1993-07-28 | 1996-10-01 | Beiersdorf, Inc. | Urea/lactate topical compositions for dry skin |
| ES2123910T3 (en) * | 1994-03-22 | 1999-01-16 | Bristol Myers Squibb Co | COMPOSITIONS CONTAINING AMPHOTERAL SALTS OF ALPHA-HYDROXIACIDES AND GLYCEROL MONOCAPRILATE. |
| FR2720643A1 (en) * | 1994-06-03 | 1995-12-08 | Clarins | Cosmetic compsn. contg. mixt. of hydroxy-acids |
| US5569651A (en) * | 1995-03-03 | 1996-10-29 | Avon Products, Inc. | Gentle anti-acne composition |
Non-Patent Citations (4)
| Title |
|---|
| MAUREEN, B.J. et al. "A Comparative Study of Lactic Acid 10% and Ammonium Lactate 12% Lotion in the Treatment of Foot Xerosis". Journal of the American Podiatric Medical Association, 2002, Vol. 92, n‘ 3, paginas 143-148. * |
| MAUREEN, B.J. et al. "A Comparative Study of Lactic Acid 10% and Ammonium Lactate 12% Lotion in the Treatment of Foot Xerosis". Journal of the American Podiatric Medical Association, 2002, Vol. 92, nº 3, páginas 143-148. * |
| THUESON, D.O. et al. "The Roles of pH and Concentration in Lactic Acid-induced Stimulation of Epidermal Turnover". American Society for Dermotologic Surgery, 1998, Vol. 24, n‘ 6, paginas 641-645. Ver pagina 644, columna 2 - pagina 645, columna 1. * |
| THUESON, D.O. et al. "The Roles of pH and Concentration in Lactic Acid-induced Stimulation of Epidermal Turnover". American Society for Dermotologic Surgery, 1998, Vol. 24, nº 6, páginas 641-645. Ver página 644, columna 2 - página 645, columna 1. * |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2222818B1 (en) | 2007-03-01 |
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