ES2217258T3 - Factor mitogeno, gen del mismo y procedimiento para su microdeteccion. - Google Patents
Factor mitogeno, gen del mismo y procedimiento para su microdeteccion.Info
- Publication number
- ES2217258T3 ES2217258T3 ES94101386T ES94101386T ES2217258T3 ES 2217258 T3 ES2217258 T3 ES 2217258T3 ES 94101386 T ES94101386 T ES 94101386T ES 94101386 T ES94101386 T ES 94101386T ES 2217258 T3 ES2217258 T3 ES 2217258T3
- Authority
- ES
- Spain
- Prior art keywords
- mitogenic factor
- gene
- microdetection
- gen
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003226 mitogen Substances 0.000 title abstract 6
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 108091034117 Oligonucleotide Proteins 0.000 abstract 2
- 241001505901 Streptococcus sp. 'group A' Species 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
- 238000013399 early diagnosis Methods 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
UN FACTOR MITOGENICO Y UN GEN QUE CODIFICA EL FACTOR MITOGENICO COMPRENDE LAS SECUENCIAS MOSTRADAS EN SEQ ID NO:1 OLIGONUCLEOTIDA CAPAZ DE HIBRIDIZAR CON EL GEN PUEDE SER USADO PARA LOS PRIMEROS PCR. EL GEN DE FACTOR MITOGENICO PUEDE SER DETECTADO POR LOS PASOS DE AMPLIFICAR Y ACUMULAR UN FRAGMENTO DEL GEN DE FACTOR MITOGENICO REPITIENDO LOS CICLOS DE LOS PCR UTILIZANDO LOS OLIGONUCLEOTIDOAS ANTERIORES Y DETECTANDO LOS FRAGMENTO ASI AMPLIFICADOS Y ACUMULADOS. EL GRUPO ESTREPTOCOCOS A PUEDE SER DETECTADO POR LA PRESENCIA DEL GEN DE FACTOR MITOGENICO. LA PRESENTE INVENCION HACE POSIBLE LA DETECCION DEL GRUPO FUERTEMENTE PATOGENICO DE ESTREPTOCOCOS A EN UNA ETAPA TEMPRANA DE LA INFECCION, Y ASI PUEDE UTILIZARSE PARA UN DIAGNOSTICO PRECOZ DE LA ENFERMEDAD INFECCIOSA CON LA BACTERIA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3738393 | 1993-02-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2217258T3 true ES2217258T3 (es) | 2004-11-01 |
Family
ID=12496010
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES94101386T Expired - Lifetime ES2217258T3 (es) | 1993-02-01 | 1994-01-31 | Factor mitogeno, gen del mismo y procedimiento para su microdeteccion. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0613947B1 (es) |
| AT (1) | ATE260976T1 (es) |
| DE (1) | DE69433581T2 (es) |
| DK (1) | DK0613947T3 (es) |
| ES (1) | ES2217258T3 (es) |
| PT (1) | PT613947E (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7005510B1 (en) | 1993-06-23 | 2006-02-28 | Beckman Instruments, Inc. | Recombinant DNase B derived from Streptococcus pyogenes |
| ATE248918T1 (de) * | 1993-06-23 | 2003-09-15 | Beckman Coulter Inc | Rekombinante dnase b aus streptococcus pyogenes |
| EP0726957B1 (en) * | 1994-08-18 | 2004-11-17 | Beckman Coulter, Inc. | RECOMBINANT DNase B DERIVED FROM STREPTOCOCCUS PYOGENES |
| AU1412702A (en) | 2000-10-27 | 2002-05-06 | Chiron Spa | Nucleic acids and proteins from streptococcus groups a and b |
| PT1648500E (pt) | 2003-07-31 | 2014-10-10 | Novartis Vaccines & Diagnostic | Composições imunogénicas para estreptococos piogenes |
| US8945589B2 (en) | 2003-09-15 | 2015-02-03 | Novartis Vaccines And Diagnostics, Srl | Immunogenic compositions for Streptococcus agalactiae |
| EP1784211A4 (en) | 2004-07-29 | 2010-06-30 | Novartis Vaccines & Diagnostic | IMMUNOGENIC COMPOSITIONS FOR GRAMPOSITIVE BACTERIA SUCH AS STREPTOCOCCUS AGALACTIAE |
| JP2008544949A (ja) | 2004-10-08 | 2008-12-11 | ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド | 化膿性レンサ球菌のための免疫激性組成物および治療用組成物 |
| MX2010002773A (es) | 2007-09-12 | 2010-03-31 | Novartis Ag | Antigenos mutantes de gas57 y anticuerpos de gas57. |
| CA2709927C (en) | 2007-12-21 | 2017-05-16 | Novartis Ag | Mutant forms of streptolysin o |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61116659A (ja) * | 1984-11-12 | 1986-06-04 | Toyo Jozo Co Ltd | ネフリテイス・ストレイン・アソシエイテツド・プロテイン測定用試薬およびそれを用いた測定法 |
| DE3637253A1 (de) * | 1986-11-03 | 1988-05-05 | Behringwerke Ag | Latex-agglutinations-verfahren zum nachweis von anti-streptokokken-desoxyribonuclease b |
-
1994
- 1994-01-31 DK DK94101386T patent/DK0613947T3/da active
- 1994-01-31 ES ES94101386T patent/ES2217258T3/es not_active Expired - Lifetime
- 1994-01-31 AT AT94101386T patent/ATE260976T1/de not_active IP Right Cessation
- 1994-01-31 EP EP94101386A patent/EP0613947B1/en not_active Expired - Lifetime
- 1994-01-31 DE DE69433581T patent/DE69433581T2/de not_active Expired - Fee Related
- 1994-01-31 PT PT94101386T patent/PT613947E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT613947E (pt) | 2004-07-30 |
| DE69433581T2 (de) | 2005-03-03 |
| DK0613947T3 (da) | 2004-07-05 |
| EP0613947A2 (en) | 1994-09-07 |
| DE69433581D1 (de) | 2004-04-08 |
| EP0613947A3 (en) | 1995-07-26 |
| EP0613947B1 (en) | 2004-03-03 |
| ATE260976T1 (de) | 2004-03-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2217258T3 (es) | Factor mitogeno, gen del mismo y procedimiento para su microdeteccion. | |
| KR101100594B1 (ko) | 감염증 병원체 검출용 프로브 및 프로브 세트, 그리고,담체 및 유전자 확인방법 | |
| CN101501219A (zh) | 病原体的鉴定 | |
| GR3032597T3 (en) | Mycobacterium primers and probes. | |
| CA2318536A1 (en) | Method of and compositions for immunization with the pseudomonas v antigen | |
| EP2671953B1 (en) | Composition and kit for detection and analysis of strains of clostridium difficile and method of detecting strains of clostridium difficile by using the same | |
| NO933678L (no) | Oligonukleotider avledet fra SOD-familien | |
| ES2094178T3 (es) | Secuencias nucleotidicas utiles como sondas especificas del tipo cebadores pct y sondas para la amplificacion y deteccion del virus del papiloma humano, y kits y procedimientos utilizados con este fin. | |
| DE59609841D1 (de) | Verfahren zur Gattungs- und speziesspezifische Identifizierung von Legionellen | |
| EP0383509A3 (en) | Nucleic acid probe for the detection of salmonella human pathogens | |
| Arriaga et al. | Detection of Rhodococcus equi by polymerase chain reaction using species-specific nonproprietary primers | |
| ATE328077T1 (de) | Gen assoziiert mit iga glomerulonephritis | |
| EP2999798B1 (en) | Method for simultaneous detection of bacteria and fungi in a biological preparation by pcr, primers as well as bacteria and fungi detection kit | |
| CA2190359A1 (en) | Nucleic acids of rochalimaea henselae and rochalimaea quintana and methods and compositions for diagnosing rochalimaea henselae and rochalimaea quintana infection | |
| EP0976837A3 (en) | Oligonucleotides for detecting enteric hemorrhagic e. coli and detection method using the same | |
| SE9002060D0 (sv) | A method of detecting an infection caused by a specific type of virus, primers, probes and a test kit | |
| GB2362212A (en) | Method for the identification and speciation of bacteria of the burkholderia cepacia complex | |
| HUP0004409A2 (hu) | Eljárás az Escherichia coli DSM 6601 törzs azonosítására | |
| Liu et al. | Epidemiological typing of Flavimonas oryzihabitans by PCR and pulsed-field gel electrophoresis | |
| Chongtrakool et al. | Invasive streptococcus pneumoniae serotype 19a in Thailand (2008-2018) | |
| MY128619A (en) | Detection of human hepatitis b virus surface antigen mutants by specific amplification and its application on gene chip | |
| Ash et al. | Molecular identification of Aeromonas sobria by using a polymerase chain reaction-probe test. | |
| Haque et al. | Identification of drug resistance genes in clinical isolates of salmonella typhi for development of diagnostic multiplex pcr | |
| ATE407223T1 (de) | Methode zum nachweis von staphylococcus aureus | |
| Falcão et al. | A virulence study of Yersinia enterocolitica O: 3 isolated from sick humans and animals in Brazil using PCR and phenotypic tests |