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ES2136167T3 - Composiciones de idebenona para tratar la enfermedad de alzheimer. - Google Patents

Composiciones de idebenona para tratar la enfermedad de alzheimer.

Info

Publication number
ES2136167T3
ES2136167T3 ES94303847T ES94303847T ES2136167T3 ES 2136167 T3 ES2136167 T3 ES 2136167T3 ES 94303847 T ES94303847 T ES 94303847T ES 94303847 T ES94303847 T ES 94303847T ES 2136167 T3 ES2136167 T3 ES 2136167T3
Authority
ES
Spain
Prior art keywords
disease
idebenone
compositions
treat alzheimer
alzheimer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94303847T
Other languages
English (en)
Inventor
Masaomi Miyamoto
Akinobu Nagaoka
Giichi Goto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ES2136167T3 publication Critical patent/ES2136167T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

UNA COMPOSICION PARA EL TRATAMIENTO DE LA ENFERMEDAD DE ALZHEIMER, CUYA COMPOSICION CONTIENE IDEBENONA EN UNA CANTIDAD QUE OSCILA ENTRE 50 MG O MAS EN UNA DOSIS. LA ADMINISTRACION ORAL DE "IDEBENONA" A UN PACIENTE CON LA ENFERMEDAD DE ALZHEIMER, A UNA DOSIS DE 50 MG O MAS POR CADA ADMINISTRACION, RESULTA EFICAZ PARA EL TRATAMIENTO DE LA ENFERMEDAD DE ALZHEIMER.
ES94303847T 1993-06-18 1994-05-27 Composiciones de idebenona para tratar la enfermedad de alzheimer. Expired - Lifetime ES2136167T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14815493 1993-06-18

Publications (1)

Publication Number Publication Date
ES2136167T3 true ES2136167T3 (es) 1999-11-16

Family

ID=15446472

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94303847T Expired - Lifetime ES2136167T3 (es) 1993-06-18 1994-05-27 Composiciones de idebenona para tratar la enfermedad de alzheimer.

Country Status (8)

Country Link
EP (1) EP0629400B1 (es)
JP (1) JPH0761923A (es)
AT (1) ATE184788T1 (es)
CA (1) CA2125822A1 (es)
DE (1) DE69420776T2 (es)
DK (1) DK0629400T3 (es)
ES (1) ES2136167T3 (es)
GR (1) GR3032041T3 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19549262C2 (de) * 1995-02-08 1997-10-09 Martin Dr Kohlmeier Präparat zur Abschätzung des Entstehungsrisikos eines beschleunigten Verlustes kognitiver Fähigkeiten
EP0788793A1 (en) * 1996-02-01 1997-08-13 Takeda Chemical Industries, Ltd. Idebenone for the treatment of dementia
EP0915696B1 (en) * 1996-07-11 2002-05-29 Takeda Chemical Industries, Ltd. ANTI-beta-AMYLOID PROTEIN-INDUCED CYTOTOXICITY COMPOSITION
US5962535A (en) * 1997-01-17 1999-10-05 Takeda Chemical Industries, Ltd. Composition for alzheimer's disease
DE69802498T2 (de) * 1997-01-17 2002-07-04 Takeda Chemical Industries, Ltd. Idebenon enthaltendes kombinationspräparat zur alzheimer behandlung
WO1999007355A1 (en) * 1997-08-12 1999-02-18 Takeda Chemical Industries, Ltd. Idebenone-containing preparation for percutaneous administration
JP2003226639A (ja) * 2002-01-31 2003-08-12 Hisamitsu Pharmaceut Co Inc 神経成長因子活性増強剤としてのビタミンｋ類を含む医薬組成物およびその使用
AR055453A1 (es) * 2004-01-06 2007-08-22 Creactivar S A Uso de la idebenona en una composicion destinada a ser aplicada sobre la piel y composicion que la comprende
MX359292B (es) 2005-06-01 2018-09-24 Bioelectron Tech Corp Sustancias terapeuticas activas redox para el tratamiento de enfermedades mitocondriales y otras condiciones y modulacion de biomarcadores de energia.
EP1986636B1 (en) 2006-02-22 2013-04-24 Edison Pharmaceuticals, Inc. Phenol and 1,4-benzoquinone derivatives for use in the treatment of mitochondrial diseases
LT3827815T (lt) 2008-09-10 2023-10-10 Ptc Therapeutics, Inc. Psichologinių raidos sutrikimų gydymas oksidacijos redukcijos atžvilgiu aktyviais vaistais
WO2014035356A1 (en) * 2012-08-31 2014-03-06 Mahmut Bilgic Tablet formulations comprising a quinone derivative active agent
AU2016369616B2 (en) 2015-12-17 2021-03-25 Ptc Therapeutics, Inc. Fluoroalkyl, fluoroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders
US12310967B2 (en) 2017-12-21 2025-05-27 Gliapharm Sa Compositions and methods of treatment for neurological disorders comprising motor neuron diseases
US12274703B2 (en) 2017-12-21 2025-04-15 Gliapharm Sa Compositions and methods of treatment for neurological disorders comprising a dementia
WO2020132378A2 (en) 2018-12-22 2020-06-25 Gliapharm Sa Compositions and methods of treatment for neurological disorders comprising depression
EP4351545A1 (en) 2021-06-07 2024-04-17 Katholieke Universiteit Leuven Idebenone in the treatment of drug resistant epilepsy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08768B2 (ja) * 1989-08-24 1996-01-10 武田薬品工業株式会社 神経成長因子分泌誘導剤

Also Published As

Publication number Publication date
DE69420776T2 (de) 2000-05-18
GR3032041T3 (en) 2000-03-31
EP0629400B1 (en) 1999-09-22
ATE184788T1 (de) 1999-10-15
DE69420776D1 (de) 1999-10-28
EP0629400A1 (en) 1994-12-21
DK0629400T3 (da) 2000-02-14
JPH0761923A (ja) 1995-03-07
CA2125822A1 (en) 1994-12-19

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