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ES2124794T3 - Procedimiento para producir granulados finos. - Google Patents

Procedimiento para producir granulados finos.

Info

Publication number
ES2124794T3
ES2124794T3 ES93922047T ES93922047T ES2124794T3 ES 2124794 T3 ES2124794 T3 ES 2124794T3 ES 93922047 T ES93922047 T ES 93922047T ES 93922047 T ES93922047 T ES 93922047T ES 2124794 T3 ES2124794 T3 ES 2124794T3
Authority
ES
Spain
Prior art keywords
fine
procedure
field
powder
produce fine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93922047T
Other languages
English (en)
Inventor
Yoshiaki Yano
Tamiji Fujimoto
Takayoshi Hidaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanegafuchi Chemical Industry Co Ltd
Original Assignee
Kanegafuchi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanegafuchi Chemical Industry Co Ltd filed Critical Kanegafuchi Chemical Industry Co Ltd
Application granted granted Critical
Publication of ES2124794T3 publication Critical patent/ES2124794T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/16—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by suspending the powder material in a gas, e.g. in fluidised beds or as a falling curtain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/10—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic in stationary drums or troughs, provided with kneading or mixing appliances
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/12—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic in rotating drums
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Fertilizers (AREA)
  • Glanulating (AREA)

Abstract

LA INVENCION SE REFIERE A UN METODO DE PRODUCCION DE UN GRANULADO FINO QUE TENGA UN TAMAÑO DE GRANO NO MAYOR A 0.2 MM QUE INCLUYE UN PASO DE GRANULACION DE ROCIADO DE UN AMALGAMADOR O UN LIQUIDO QUE CONTENGA EL AMALGAMADOR Y UN SURFACTANTE A LA SUPERFICIE DEL MATERIAL EN FORMA DE POLVO FINO QUE TENGA UN TAMAÑO MEDIO DE PARTICULA NO MAYOR A 10(MU)M BAJO CONDICIONES DE SINTERIZACION, PRENSADO O FLUIDIZACION, Y AL GRANULADO FINO RESULTANTE ASI OBTENIDO. EN EL CAMPO DE LOS MEDICAMENTOS, LA PRESENTE INVENCION HACE POSIBLE PRODUCIR PRODUCTOS FARMACEUTICOS QUE PUEDAN MANTENER ALTOS CONTENIDOS DE COMPONENTES MEDICINALES Y UNA BASE LEVEMENTE SOLUBLES Y LEVEMENTE ABSORBIBLE. EN EL CAMPO DE LA ALIMENTACION Y DE LOS FERTILIZANTES, LA INVENCION PUEDE SUMINISTRAR TAMBIEN UN GRANULADO FINO QUE TENGA UNA ALTA POTENCIALIDAD DE USO COMO POLVO.
ES93922047T 1992-10-09 1993-10-06 Procedimiento para producir granulados finos. Expired - Lifetime ES2124794T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP29790592 1992-10-09

Publications (1)

Publication Number Publication Date
ES2124794T3 true ES2124794T3 (es) 1999-02-16

Family

ID=17852618

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93922047T Expired - Lifetime ES2124794T3 (es) 1992-10-09 1993-10-06 Procedimiento para producir granulados finos.

Country Status (9)

Country Link
US (1) US5547683A (es)
EP (1) EP0616841B1 (es)
JP (1) JP3492688B2 (es)
KR (1) KR100294525B1 (es)
CN (1) CN1089234C (es)
CA (1) CA2124568C (es)
DE (1) DE69322764T2 (es)
ES (1) ES2124794T3 (es)
WO (1) WO1994008709A1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8980870B2 (en) 2002-09-24 2015-03-17 Boehringer Ingelheim International Gmbh Solid telmisartan pharmaceutical formulations

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2250191C (en) * 1996-03-26 2005-11-15 Eli Lilly And Company Benzothiophenes, formulations containing same, and methods
JPH11514001A (ja) * 1996-07-01 1999-11-30 ファイザー・インク バージニアマイシン混合物
ES2129010B1 (es) * 1997-01-02 2000-01-16 Gold Oscar Composicion de accion prolongada en granulos que contienen 4-nitro-2- fenoximetansulfonanilida y su procedimiento de preparacion.
US6045829A (en) * 1997-02-13 2000-04-04 Elan Pharma International Limited Nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers
FR2760190B1 (fr) * 1997-02-28 1999-04-09 Adir Composition pharmaceutique pour la liberation programmee de dexfenfluramine
US6013280A (en) * 1997-10-07 2000-01-11 Fuisz Technologies Ltd. Immediate release dosage forms containing microspheres
JP2007246539A (ja) * 1997-10-20 2007-09-27 Dainippon Sumitomo Pharma Co Ltd 速溶性医薬組成物
JP2000128774A (ja) * 1998-10-26 2000-05-09 Tanabe Seiyaku Co Ltd 薬物を含有する球形微粒子の製法
FR2791905B1 (fr) * 1999-04-09 2001-09-14 Toulouse Inst Nat Polytech Procede d'enrobage et de pelliculage de poudres fines dans un enrobeur a lit fluidise
US6417227B1 (en) 1999-04-28 2002-07-09 Cg And Associates Methods of delivery of cetyl myristoleate
DE10005280A1 (de) * 2000-02-07 2001-08-09 Bayer Ag Partikuläre Zusammensetzung, Verfahren zu ihrer Herstellung und deren Verwendung
WO2002015880A2 (en) * 2000-08-25 2002-02-28 Merck Patent Gmbh Powdered mannitol and mannitol-containing compositions
WO2002102167A1 (en) * 2001-06-19 2002-12-27 E.I. Du Pont De Nemours And Company Process for dry coating a food particle or encapsulating a frozen liquid particle
JP2003001091A (ja) * 2001-06-26 2003-01-07 Pauretsuku:Kk 流動層造粒・コーティング方法
US7122525B2 (en) * 2001-11-21 2006-10-17 Activbiotics, Inc. Targeted therapeutics and uses thereof
WO2003051299A2 (en) * 2001-12-13 2003-06-26 Activbiotics, Inc. Sulfhydryl rifamycins and uses thereof
US20040131730A1 (en) * 2002-06-19 2004-07-08 Dalziel Sean M. Process for dry coating a food particle or encapsulating a frozen liquid particle
JP2006501310A (ja) * 2002-08-29 2006-01-12 アクティブバイオティクス インコーポレイティッド クロストリジウム・ディフィシレの感染およびそれに関係する疾患を治療するための方法および試薬
US9060941B2 (en) * 2002-09-20 2015-06-23 Actavis, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
TW200418485A (en) * 2002-09-23 2004-10-01 Activbiotics Inc Rifalazil compositions and therapeutic regimens
BRPI0407074A (pt) * 2003-01-29 2006-01-24 Takeda Pharmaceutical Método para produção de uma preparação revestida, preparação revestida, e, método para melhorar a dissolução do cloridreto de pioglitazona de uma preparação revestida com cloridreto de pioglitazona
US7442387B2 (en) * 2003-03-06 2008-10-28 Astellas Pharma Inc. Pharmaceutical composition for controlled release of active substances and manufacturing method thereof
US20040253308A1 (en) * 2003-04-29 2004-12-16 Barr Laboratories, Inc. Surface-treated modafinil particles
CA2531486C (en) * 2003-07-11 2012-10-02 Antonio A. Albano Saquinavir mesylate oral dosage form
FR2857591B1 (fr) * 2003-07-17 2007-11-02 Ethypharm Sa Particules comprenant un principe actif sous forme de co-precipite
CN1894259A (zh) * 2003-08-22 2007-01-10 活跃生物工艺学公司 利福霉素类似物及其应用
US7820652B2 (en) * 2003-09-24 2010-10-26 Activbiotics Pharma, Llc Regimen for the administration of rifamycin-class antibiotics
US20050123602A1 (en) * 2003-09-25 2005-06-09 Michaelis Arthur F. Rifalazil formulations
JP2007513961A (ja) * 2003-12-10 2007-05-31 アクティブバイオティクス インコーポレイティッド リファマイシンアナログおよびその使用法
CN1918172B (zh) * 2003-12-23 2011-09-14 活跃生物工艺学公司 利福霉素类似物及其用途
EP1698349A4 (en) * 2003-12-25 2009-12-16 Takeda Pharmaceutical PROCESS FOR IMPROVING GRANULATION ABILITY
EP1642922B2 (en) * 2004-09-30 2015-02-25 Shin-Etsu Chemical Co., Ltd. Cold water-soluble polymer particles and method for preparing
CA2642761A1 (en) * 2006-02-23 2007-08-30 Iomedix Sleep International Srl Compositions and methods for the induction and maintenance of quality sleep
CA2651159A1 (en) * 2006-04-06 2007-10-18 Activbiotics Pharma Llc Pharmaceutical compositions and uses thereof
US8071153B2 (en) * 2006-04-17 2011-12-06 Meiji Seika Kaisha, Ltd. Whey protein-containing granules and method of producing the same
JP4065902B2 (ja) * 2006-04-28 2008-03-26 ライオン株式会社 造粒粒子、錠剤、及び造粒粒子の製造方法
JP2007314529A (ja) * 2006-04-28 2007-12-06 Lion Corp 造粒粒子、錠剤、及び造粒粒子の製造方法
WO2008018569A1 (en) * 2006-08-10 2008-02-14 Takeda Pharmaceutical Company Limited Pharmaceutical composition
EP2313099A4 (en) * 2008-07-07 2011-08-10 Activbiotics Pharma Llc USE OF RIFALAZIL TO TREAT COLON DISEASES
GB0814953D0 (en) * 2008-08-18 2008-09-24 Unilever Plc Improvements relating to nanodisperse compositions
CA2753860A1 (en) * 2009-03-06 2010-09-10 Xenoport, Inc. Oral dosage forms having a high loading of a gabapentin prodrug
RU2012104912A (ru) * 2009-07-17 2013-08-27 КЕЭ-ФЬЮЖН 2200, Инк. Частицы, содержащие противомикробные агенты
JP5825686B2 (ja) * 2010-03-31 2015-12-02 エスエス製薬株式会社 難水溶性薬物含有微粒子造粒物の製造法
WO2012103116A1 (en) * 2011-01-24 2012-08-02 Activbiotics Pharma, Llc Pulmonary administration of rifalazil and analogs thereof
JP2017500332A (ja) * 2013-12-23 2017-01-05 ラボラトリオス・デル・ドクトル・エステベ・ソシエダッド・アノニマ 経口医薬組成物
CN108261396B (zh) * 2016-12-30 2021-12-24 北京化工大学 一种制粒方法
JP7389620B2 (ja) * 2019-11-11 2023-11-30 花王株式会社 造粒物の製造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS563326B2 (es) * 1972-09-11 1981-01-24
JPS5432176A (en) * 1977-08-15 1979-03-09 Sanyo Kokusaku Pulp Co Ltd Granulating and drying method by fluidization
JPS55129220A (en) * 1980-02-08 1980-10-06 Yamanouchi Pharmaceut Co Ltd Composition for solid preparation containing hardly soluble medicinal component having rapid action and high bioavailability
GB2072037A (en) * 1980-03-20 1981-09-30 Standard Telephones Cables Ltd Fluidising fine powder
JPS6168133A (ja) * 1984-09-08 1986-04-08 Shinjiro Tsuji 造粒方法
JPS63240934A (ja) * 1987-03-28 1988-10-06 Taisho Pharmaceut Co Ltd 薬物の造粒法
JPH06128147A (ja) * 1992-10-20 1994-05-10 Masayasu Sugihara 水難溶性薬品の溶解性改善方法およびそれにより得られた薬品組成物

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8980870B2 (en) 2002-09-24 2015-03-17 Boehringer Ingelheim International Gmbh Solid telmisartan pharmaceutical formulations

Also Published As

Publication number Publication date
EP0616841B1 (en) 1998-12-23
CA2124568A1 (en) 1994-04-28
WO1994008709A1 (fr) 1994-04-28
CA2124568C (en) 2003-11-11
EP0616841A4 (en) 1996-04-03
EP0616841A1 (en) 1994-09-28
DE69322764D1 (de) 1999-02-04
US5547683A (en) 1996-08-20
CN1089234C (zh) 2002-08-21
CN1091628A (zh) 1994-09-07
KR100294525B1 (ko) 2001-09-17
DE69322764T2 (de) 1999-05-06
JP3492688B2 (ja) 2004-02-03

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