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ES2119268T3 - Procedimiento para fabricar ranitidina base de calidad farmaceutica. - Google Patents

Procedimiento para fabricar ranitidina base de calidad farmaceutica.

Info

Publication number
ES2119268T3
ES2119268T3 ES95107137T ES95107137T ES2119268T3 ES 2119268 T3 ES2119268 T3 ES 2119268T3 ES 95107137 T ES95107137 T ES 95107137T ES 95107137 T ES95107137 T ES 95107137T ES 2119268 T3 ES2119268 T3 ES 2119268T3
Authority
ES
Spain
Prior art keywords
ranitidine
manufacture
procedure
quality base
pharmaceutical quality
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95107137T
Other languages
English (en)
Inventor
Jag Mohan Khanna
Naresh Kumar
Brij Khera
Purna Chandra Ray
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ranbaxy Laboratories Ltd
Original Assignee
Ranbaxy Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/265,308 external-priority patent/US5696275A/en
Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Application granted granted Critical
Publication of ES2119268T3 publication Critical patent/ES2119268T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

UN PROCESO PARA LA FABRICACION DE UNA BASE (N-[2-[[[5-(DIMETILAMINO)METIL]-2-FURANIL]METIL]TIO]ETIL-N''-METIL-2-NITRO-1,1ETENEDIAMINA) DE RANITIDINA DE GRADO FARMACEUTICO. ESTUDIOS FARMACOLOGICOS IN VITRO E IN VIVO Y ESTUDIOS DE TOXICIDAD AGUDA INDICAN QUE ESTA COMPOSICION ES TAN ACTIVA Y SEGURA COMO EL HIDROCLORURO DE RANITIDINA FORMA F2.
ES95107137T 1994-06-24 1995-05-11 Procedimiento para fabricar ranitidina base de calidad farmaceutica. Expired - Lifetime ES2119268T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/265,308 US5696275A (en) 1994-05-13 1994-06-24 Process for the manufacture of pharmaceutical grade ranitidine base

Publications (1)

Publication Number Publication Date
ES2119268T3 true ES2119268T3 (es) 1998-10-01

Family

ID=23009923

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95107137T Expired - Lifetime ES2119268T3 (es) 1994-06-24 1995-05-11 Procedimiento para fabricar ranitidina base de calidad farmaceutica.

Country Status (3)

Country Link
EP (1) EP0697411B1 (es)
DE (1) DE69503196T2 (es)
ES (1) ES2119268T3 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999065890A1 (en) * 1998-06-17 1999-12-23 Russinsky Limited Ranitidine adduct
YU52598A (sh) * 1998-11-19 2001-05-28 D.D. Zdravlje- sektor za istraživanje i razvoj POSTUPAK ZA sintezu N-[2[[[5=[(DIALKILAMINO)METIL]-2= FURANIL]METIL]TIO]ETIL]-N'-ALKIL-2-NITRO 1,1 ALKENDIAMINA I NJIHOVIH HIDROHLORIDA
CN108017601B (zh) * 2017-12-28 2021-07-13 云鹏医药集团有限公司 一种精制雷尼替丁碱的方法
CN108727312B (zh) * 2018-08-03 2021-05-18 上海金城素智药业有限公司 雷尼替丁口服制剂治疗糜烂性食管炎的新适应症

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
EP0285681B1 (de) * 1987-04-06 1993-03-10 HEUMANN PHARMA GMBH & CO Verfahren zur Herstellung von Nitroethenderivaten

Also Published As

Publication number Publication date
DE69503196D1 (de) 1998-08-06
EP0697411A1 (en) 1996-02-21
DE69503196T2 (de) 1999-02-18
EP0697411B1 (en) 1998-07-01

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