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ES2103675A1 - Nuevas piperidinas sustituidas. - Google Patents

Nuevas piperidinas sustituidas.

Info

Publication number
ES2103675A1
ES2103675A1 ES09500022A ES9500022A ES2103675A1 ES 2103675 A1 ES2103675 A1 ES 2103675A1 ES 09500022 A ES09500022 A ES 09500022A ES 9500022 A ES9500022 A ES 9500022A ES 2103675 A1 ES2103675 A1 ES 2103675A1
Authority
ES
Spain
Prior art keywords
group
halogen
new substituted
substituted piperidines
alkoxy group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09500022A
Other languages
English (en)
Other versions
ES2103675B1 (es
Inventor
Soto Jose Maria Prieto
Noguera Ferran Pujol
Duran Carles Puig
Noverola Armando Vega
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Almirall SA
Original Assignee
Laboratorios Almirall SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Almirall SA filed Critical Laboratorios Almirall SA
Priority to ES9500022A priority Critical patent/ES2103675B1/es
Publication of ES2103675A1 publication Critical patent/ES2103675A1/es
Application granted granted Critical
Publication of ES2103675B1 publication Critical patent/ES2103675B1/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Landscapes

  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

UN COMPUESTO EL CUAL ES UNA PIPERIDINA DE FORMULA (I): FORMULA EN DONDE: R1 ES UN GRUPO C1-C4 ALCOXI; R2 ES HIDROGENO, HALOGENO O UN GRUPO C1-C4 ALCOXI, O R1 Y R2 JUNTOS FORMAN UN GRUPO ETILENDIOXI; R3ES UN HALOGENO; R4 ES UN GRUPO FENIL -(C1-C4) ALQUILO EL CUAL ESTA OPCIONALMENTE SUSTITUIDO POR UN SUSTITUYENTE SELECCIONADO ENTRE UN HALOGENO O UN GRUPO C1-C4 ALQUILO O C1-C4 ALCOXI; X ES UN OXIGENO O UN GRUPO NH; M ES UN 1 O 2; Y N ES 1 O 2, CON LA CONDICION DE QUE M + N = 3; O UNA SAL FARMACOLOGICAMENTE ACEPTABLE DEL MISMO.
ES9500022A 1995-01-10 1995-01-10 Nuevas piperidinas sustituidas. Expired - Lifetime ES2103675B1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9500022A ES2103675B1 (es) 1995-01-10 1995-01-10 Nuevas piperidinas sustituidas.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9500022A ES2103675B1 (es) 1995-01-10 1995-01-10 Nuevas piperidinas sustituidas.

Publications (2)

Publication Number Publication Date
ES2103675A1 true ES2103675A1 (es) 1997-09-16
ES2103675B1 ES2103675B1 (es) 1998-07-01

Family

ID=8289093

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9500022A Expired - Lifetime ES2103675B1 (es) 1995-01-10 1995-01-10 Nuevas piperidinas sustituidas.

Country Status (1)

Country Link
ES (1) ES2103675B1 (es)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002533337A (ja) * 1998-12-22 2002-10-08 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 胃腸障害の処置のための４−（アミノメチル）−ピペリジンベンズアミド
WO2005000837A1 (en) * 2003-06-19 2005-01-06 Janssen Pharmaceutica N.V. Aminosulfonyl substituted 4-(aminomethyl)-piperidine benzamides as 5ht4-antagonists
WO2005003121A1 (en) * 2003-06-19 2005-01-13 Janssen Pharmaceutica N.V. Hydroxycarbonylphenyl substituted 4-(aminomethyl)-piperidine benzamides as 5ht4-antagonists
WO2010112865A1 (en) * 2009-04-01 2010-10-07 Serodus As 5-ht receptor modulating compounds
US8829028B2 (en) 2002-05-16 2014-09-09 Serodus As 5-HT4 receptor antagonists for the treatment of heart failure

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1194505A (en) * 1968-05-21 1970-06-10 Science Union & Cie Piperidinol Derivatives and Process for Preparing Them
EP0235463A2 (en) * 1985-12-20 1987-09-09 A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents
WO1991010647A1 (en) * 1990-01-06 1991-07-25 Pfizer Limited Muscarinic receptor antagonists

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1194505A (en) * 1968-05-21 1970-06-10 Science Union & Cie Piperidinol Derivatives and Process for Preparing Them
EP0235463A2 (en) * 1985-12-20 1987-09-09 A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents
WO1991010647A1 (en) * 1990-01-06 1991-07-25 Pfizer Limited Muscarinic receptor antagonists

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002533337A (ja) * 1998-12-22 2002-10-08 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 胃腸障害の処置のための４−（アミノメチル）−ピペリジンベンズアミド
US8829028B2 (en) 2002-05-16 2014-09-09 Serodus As 5-HT4 receptor antagonists for the treatment of heart failure
US7498347B2 (en) 2003-06-19 2009-03-03 Janssen Pharmaceutica, N.V. Hydroxycarbonylphenyl substituted 4-(aminomethyl)-piperidine benzamides as 5HT4 antagonists
JP2007526874A (ja) * 2003-06-19 2007-09-20 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ５ｈｔ４−アンタゴニストとしてのヒドロキシカルボニルフェニル置換４−（アミノメチル）−ピペリジンベンズアミド
EA009259B1 (ru) * 2003-06-19 2007-12-28 Янссен Фармацевтика Н.В. Аминосульфонилзамещенные 4-(аминометил)пиперидинбензамиды в качестве 5ht-антагонистов
EA009464B1 (ru) * 2003-06-19 2007-12-28 Янссен Фармацевтика Н.В. Бензамиды 4-(аминометил)пиперидина, замещённого гидроксикарбонилфенилом, в качестве антагонистов 5нт-рецепторов
WO2005003121A1 (en) * 2003-06-19 2005-01-13 Janssen Pharmaceutica N.V. Hydroxycarbonylphenyl substituted 4-(aminomethyl)-piperidine benzamides as 5ht4-antagonists
US7652040B2 (en) 2003-06-19 2010-01-26 Janssen Pharmaceutica N.V. Aminosulfonyl substituted 4-(aminomethyl)-piperidine benzamides as 5HT4-antagonists
AU2004254191B2 (en) * 2003-06-19 2010-03-11 Janssen Pharmaceutica N.V. Hydroxycarbonylphenyl substituted 4-(aminomethyl)-piperidine benzamides as 5HT4-antagonists
EP2305254A1 (en) * 2003-06-19 2011-04-06 Janssen Pharmaceutica NV Aminosulfonyl substituted 4-(aminomethyl)-piperidine benzamides as 5HT4-antagonists for the treatment of gatrointestinal conditions
US8334304B2 (en) 2003-06-19 2012-12-18 Janssen Pharmaceutica N.V. Aminosulfonyl substituted 4-(aminomethyl)-piperidine benzamides as 5HT4-antagonists
WO2005000837A1 (en) * 2003-06-19 2005-01-06 Janssen Pharmaceutica N.V. Aminosulfonyl substituted 4-(aminomethyl)-piperidine benzamides as 5ht4-antagonists
WO2010112865A1 (en) * 2009-04-01 2010-10-07 Serodus As 5-ht receptor modulating compounds

Also Published As

Publication number Publication date
ES2103675B1 (es) 1998-07-01

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