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ES2103313T3 - Esteres de acido fosforico y su utilizacion en la preparacion de superficies biocompatibles. - Google Patents

Esteres de acido fosforico y su utilizacion en la preparacion de superficies biocompatibles.

Info

Publication number
ES2103313T3
ES2103313T3 ES91918676T ES91918676T ES2103313T3 ES 2103313 T3 ES2103313 T3 ES 2103313T3 ES 91918676 T ES91918676 T ES 91918676T ES 91918676 T ES91918676 T ES 91918676T ES 2103313 T3 ES2103313 T3 ES 2103313T3
Authority
ES
Spain
Prior art keywords
pct
formula
group
preparation
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91918676T
Other languages
English (en)
Inventor
Roderick William Jonath Bowers
Peter William Stratford
Stephen Alister Jones
Jeremy Colin Russell
Michael John Driver
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Vascular Devices Ltd
Original Assignee
Biocompatibles Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909024012A external-priority patent/GB9024012D0/en
Priority claimed from GB909024011A external-priority patent/GB9024011D0/en
Application filed by Biocompatibles Ltd filed Critical Biocompatibles Ltd
Application granted granted Critical
Publication of ES2103313T3 publication Critical patent/ES2103313T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/12—Chemical modification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0076—Chemical modification of the substrate
    • A61L33/0082—Chemical modification of the substrate by reacting with an organic compound other than heparin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503—Five-membered rings
    • C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
    • C07F9/6521—Six-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Materials For Medical Uses (AREA)

Abstract

SE PRESENTA UN METODO PARA LA PREPARACION DE COMPUESTOS DE LA FORMULA I EN LA QUE Z ES HIDROGENO O -NHZ ES UN GRUPO DE AMINO ACTIVADO CAPAZ DE REACCIONAR CON UNA SUPERFICIE, LOS GRUPOS R SON IGUALES O DIFERENTES Y CADA UNO ES UN GRUPO DE ALQUIL C1-C4 RECTO O RAMIFICADO, PREFERIBLEMENTE METIL, N VALE ENTRE 2 Y 6, Y X ES UN GRUPO DE ALQUILENO C1-C20 RECTO O RAMIFICADO, O X ES UN GRUPO DE LA FORMULA -(CH2CH2O)B-, O BIEN -(CH2)C-AR-(CH2)D RENTES Y VALEN CADA UNA ENTRE 0 Y 5, Y AR ES UN GRUPO DE FENIL PARA O METADISUSTITUIDO (PREFERIBLEMENTE UN GRUPO DE FENIL PARADISUSTITUIDO) QUE ESTA OPCIONALMENTE SUSTITUIDO ADEMAS POR UNO O MAS GRUPOS DE ALQUIL C1-C4, O UNA SAL DE ADICION ACIDA DEL MISMO O UN HIDRATO DEL MISMO, ASIMISMO SE PRESENTAN LOS NUEVOS COMPUESTOS DE LA FORMULA I Y LAS SALES E HIDRATOS DE LOS MISMOS Y EL USO DE LOS COMPUESTOS DE LA FORMULA I Y LAS SALES E HIDRATOS DE LOS MISMOS EN EL TRATAMIENTO DE SUPERFICIES PARA VOLVERLAS MAS BIOCOMPATIBLES.
ES91918676T 1990-11-05 1991-11-05 Esteres de acido fosforico y su utilizacion en la preparacion de superficies biocompatibles. Expired - Lifetime ES2103313T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909024012A GB9024012D0 (en) 1990-11-05 1990-11-05 Coating method
GB909024011A GB9024011D0 (en) 1990-11-05 1990-11-05 Coating compounds

Publications (1)

Publication Number Publication Date
ES2103313T3 true ES2103313T3 (es) 1997-09-16

Family

ID=26297904

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91918676T Expired - Lifetime ES2103313T3 (es) 1990-11-05 1991-11-05 Esteres de acido fosforico y su utilizacion en la preparacion de superficies biocompatibles.

Country Status (8)

Country Link
US (1) US5599587A (es)
EP (1) EP0556216B1 (es)
JP (1) JPH06501697A (es)
AT (1) ATE154023T1 (es)
DE (1) DE69126440T2 (es)
DK (1) DK0556216T3 (es)
ES (1) ES2103313T3 (es)
WO (1) WO1992007858A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9118597D0 (en) * 1991-08-30 1991-10-16 Biocompatibles Ltd Polymer treatments
JPH05220218A (ja) * 1992-02-13 1993-08-31 Norio Nakabayashi 抗血栓性再生セルロース系膜及びその製造方法
GB9301702D0 (en) * 1993-01-28 1993-03-17 Biocompatibles Ltd New materials
GB9301701D0 (en) * 1993-01-28 1993-03-17 Biocompatibles Ltd New zwitterionic materials
GB9415926D0 (en) * 1994-08-04 1994-09-28 Biocompatibles Ltd New materials
AU5363596A (en) * 1995-03-17 1996-10-08 Regents Of The University Of Minnesota Biocompatible materials
EP0913416B1 (en) * 1997-04-17 2005-10-19 Toyobo Co., Ltd. Biocompatible polymers
AU7781298A (en) * 1997-06-04 1998-12-21 Biocompatibles Limited Phosphate compounds
WO1999011202A1 (en) * 1997-09-05 1999-03-11 Icet, Inc. Biomimetic calcium phosphate implant coatings and methods for making the same
JP2004513981A (ja) * 2000-07-17 2004-05-13 プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ 生物種の吸着に耐える表面
EP1577360B1 (en) * 2002-11-25 2017-09-06 Shiseido Company Limited Method of modifying surface of material
JP3852942B2 (ja) * 2004-05-24 2006-12-06 株式会社資生堂 水中分散性化粧料用粉体
JP4191225B2 (ja) 2007-01-18 2008-12-03 株式会社資生堂 表面改質方法及び表面改質材料
CN109879823B (zh) * 2019-03-11 2022-08-12 海思美域(深圳)科技有限公司 一种化合物、抗菌整理液及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2041377B (en) * 1979-01-22 1983-09-28 Woodroof Lab Inc Bio compatible and blood compatible materials and methods
JPS58154591A (ja) * 1982-03-09 1983-09-14 Tadao Nakaya リン脂質類似モノマ−の製造法
GB8401534D0 (en) * 1984-01-20 1984-02-22 Royal Free Hosp School Med Biocompatible surfaces
JPS60184093A (ja) * 1984-03-01 1985-09-19 Mitsubishi Chem Ind Ltd リン脂質類似モノマ−の製造法
JPS60204791A (ja) * 1984-03-30 1985-10-16 Mitsubishi Chem Ind Ltd リン脂質類似モノマ−の製造方法
JPS60204711A (ja) * 1984-03-30 1985-10-16 Mitsubishi Chem Ind Ltd 薬理活性物質の徐放方法
JPH0665677B2 (ja) * 1985-03-09 1994-08-24 三菱化成株式会社 リン脂質類似構造を有するジオ−ルおよびその製造方法
US4888328A (en) * 1988-03-10 1989-12-19 Hoeschst-Roussel Incorporated Alkoxycarbonylalkylphospholipids and alkylaminocarbonylalkylphospholipids
GB9004881D0 (en) * 1990-03-05 1990-05-02 Biocompatibles Ltd Method of improving the ocular of synthetic polymers haemo and biocompatibility

Also Published As

Publication number Publication date
DE69126440D1 (de) 1997-07-10
EP0556216B1 (en) 1997-06-04
JPH06501697A (ja) 1994-02-24
US5599587A (en) 1997-02-04
EP0556216A1 (en) 1993-08-25
WO1992007858A1 (en) 1992-05-14
DE69126440T2 (de) 1997-09-18
DK0556216T3 (da) 1997-12-22
ATE154023T1 (de) 1997-06-15

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