[go: up one dir, main page]

ES2102221T3 - Derivados de aminooxi-amino-alcanos ramificados que inhiben la ornitina-descarboxilasa. - Google Patents

Derivados de aminooxi-amino-alcanos ramificados que inhiben la ornitina-descarboxilasa.

Info

Publication number
ES2102221T3
ES2102221T3 ES94913517T ES94913517T ES2102221T3 ES 2102221 T3 ES2102221 T3 ES 2102221T3 ES 94913517 T ES94913517 T ES 94913517T ES 94913517 T ES94913517 T ES 94913517T ES 2102221 T3 ES2102221 T3 ES 2102221T3
Authority
ES
Spain
Prior art keywords
pct
aminooxi
alkans
ramified
decarboxylase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94913517T
Other languages
English (en)
Inventor
Jorg Frei
Jaroslav Stanek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG, Novartis AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of ES2102221T3 publication Critical patent/ES2102221T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C07C239/08—Hydroxylamino compounds or their ethers or esters
    • C07C239/20—Hydroxylamino compounds or their ethers or esters having oxygen atoms of hydroxylamino groups etherified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE DESCRIBEN LOS COMPONENTES DE LA FORMULA (I) EN LA QUE (A) CUATRO DE LOS RADICALES R1,R2,R3,R4,R5 Y R6 SON HIDROGENO Y LOS OTROS INDEPENDIENTEMENTE UNO DEL OTRO SON EN CADA CASO ALQUILO C1-C2, ESOS GRUPOS ESTANDO UNIDOS AL MISMO ATOMO DE CARBONO O A DOS ATOMOS DE CARBONO DIFERENTES, O (B) CINCO DE LOS RADICALES R1,R2,R3,R4,R5 Y R6 SON HIDROGENO Y EL OTRO RADICAL ES ALQUILO C1-C2 O HIDROXIMETILO, O SUS SALES. LOS COMPONENTES DE LA FORMULA (I) Y SUS SALES SON INHIBIDORES DECARBOXILASA ORNITINA.
ES94913517T 1993-04-13 1994-04-02 Derivados de aminooxi-amino-alcanos ramificados que inhiben la ornitina-descarboxilasa. Expired - Lifetime ES2102221T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH112993 1993-04-13

Publications (1)

Publication Number Publication Date
ES2102221T3 true ES2102221T3 (es) 1997-07-16

Family

ID=4203174

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94913517T Expired - Lifetime ES2102221T3 (es) 1993-04-13 1994-04-02 Derivados de aminooxi-amino-alcanos ramificados que inhiben la ornitina-descarboxilasa.

Country Status (18)

Country Link
US (1) US5610195A (es)
EP (1) EP0644873B1 (es)
JP (1) JPH07508046A (es)
CN (1) CN1034930C (es)
AT (1) ATE150009T1 (es)
AU (1) AU673073B2 (es)
CA (1) CA2135781A1 (es)
CZ (1) CZ7995A3 (es)
DE (1) DE69402021T2 (es)
DK (1) DK0644873T3 (es)
ES (1) ES2102221T3 (es)
GR (1) GR3023429T3 (es)
HU (1) HUT72751A (es)
NZ (1) NZ265253A (es)
PL (1) PL306765A1 (es)
RU (1) RU95110939A (es)
SK (1) SK3795A3 (es)
WO (1) WO1994024094A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5516806A (en) * 1993-04-13 1996-05-14 Ciba-Geigy Corporation Ornithine decarboxylase inhibiting cyclic aminooxy compounds
US20030166554A1 (en) * 2001-01-16 2003-09-04 Genset, S.A. Treatment of CNS disorders using D-amino acid oxidase and D-aspartate oxidase antagonists
US20030185754A1 (en) * 2001-01-16 2003-10-02 Genset, S.A. Treatment of CNS disorders using D-amino acid oxidase and D-aspartate oxidase antagonists

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB974163A (en) * 1960-04-08 1964-11-04 Ciba Ltd Manufacture of 1-amino-ªÏ-hydroxylamino-alkanes
US3137705A (en) * 1960-04-08 1964-06-16 Ciba Geigy Corp Hydroxylamino compounds
US3869278A (en) * 1972-07-27 1975-03-04 Merrill Wilcox Hydroxylamines and derivatives thereof as abscission agents
US4390534A (en) * 1978-12-29 1983-06-28 Fujisawa Pharmaceutical Co., Ltd. Cephem and cepham compounds
DE3501616A1 (de) * 1985-01-17 1986-07-17 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von hydroxylamin-derivaten
US4853467A (en) * 1987-05-19 1989-08-01 Bristol-Myers Company Nitrogen containing derivatives of epipodophyllotoxin glucosides
GB8729521D0 (en) * 1987-12-18 1988-02-03 May & Baker Ltd New compositions of matter
EP0369944A1 (de) * 1988-11-18 1990-05-23 Ciba-Geigy Ag Substituierte Oxadiaminobutane
CA2014880A1 (en) * 1989-04-27 1990-10-27 Indu Sawhney Thiazole derivatives
NO903360L (no) * 1989-08-11 1991-02-12 Ici Pharma Antibiotiske forbindelser.
EP0483427A1 (en) * 1990-11-01 1992-05-06 The Procter & Gamble Company Amine deodorant composition and method of deodorization
US5516806A (en) * 1993-04-13 1996-05-14 Ciba-Geigy Corporation Ornithine decarboxylase inhibiting cyclic aminooxy compounds

Also Published As

Publication number Publication date
CZ7995A3 (en) 1995-10-18
PL306765A1 (en) 1995-04-18
HU9500095D0 (en) 1995-03-28
US5610195A (en) 1997-03-11
EP0644873B1 (en) 1997-03-12
DE69402021T2 (de) 1997-10-30
GR3023429T3 (en) 1997-08-29
WO1994024094A1 (en) 1994-10-27
CN1034930C (zh) 1997-05-21
DK0644873T3 (da) 1997-04-07
EP0644873A1 (en) 1995-03-29
NZ265253A (en) 1996-10-28
RU95110939A (ru) 1996-10-27
SK3795A3 (en) 1995-05-10
DE69402021D1 (en) 1997-04-17
AU6564694A (en) 1994-11-08
CN1104831A (zh) 1995-07-05
ATE150009T1 (de) 1997-03-15
JPH07508046A (ja) 1995-09-07
AU673073B2 (en) 1996-10-24
HUT72751A (en) 1996-05-28
CA2135781A1 (en) 1994-10-27

Similar Documents

Publication Publication Date Title
DK0665844T3 (da) Substituerede benzylaminoquinuclidinforbindelser som antagonister af substans P
DK41193D0 (da) Ionkanalaabnere
ES2126068T3 (es) Derivados de estilbeno citotoxicos y composicion farmaceutica que los contiene.
ES2114645T3 (es) Utilizacion de un fosfato de alfa-tocoferol, o de uno de sus derivados para la preparacion de una composicion cosmetica, dermatologica o farmaceutica, de actividad anti-radicalar; composicion asi obtenida.
ATE227719T1 (de) Heteroaryl-zyklische acetale
BR9510420A (pt) Azetidin-2-onas substituìdas para o tratamento de aterosclerose
BR9611175A (pt) Compostos ou suas composições e uso dos mesmo
YU68792A (sh) Postupak za dobivanje derivata bakatina iii i 10-dezacetil-bakatina iii
ES2105617T3 (es) Derivados de piperacina como antagonistas de 5-ht.
ATE161717T1 (de) Antivirale mittel
ES2119187T3 (es) Nuevos derivados de urea, su preparacion y utilizacion.
BR9506552A (pt) Método de inibição de integrase retroviral
ES2102221T3 (es) Derivados de aminooxi-amino-alcanos ramificados que inhiben la ornitina-descarboxilasa.
ATE150448T1 (de) Ornithine-decarboxylase hemmende cyclische aminooxy-verbindungen
FR2726271B1 (fr) Derives de 6-polyfluoroalcoxy-2-aminobenzothiazole
ES2149817T3 (es) Piridinas sustituidas, su preparacion y uso farmaceutico.
KR970706280A (ko) 5-HT1A 길항제로서의 비사이클릭 카복스아미드(Bicyclic carboxamides as 5-HT1 antagonists)
FI962301A0 (fi) Substituoidut aminoalkyyliaminopyridiinit
DE69905144D1 (de) N,N'-Diacylthiocystine
TW282458B (es)
DK0544171T3 (da) Anvendelse af 5,6-dihydro-dibenz(b,e)azepin-6,11-dion-11-oximer til fremstilling af antiretrovirale midler
KR960700053A (ko) 방사선회복제로서 리루졸의 이용(application of riluzole as a radiorestorer)
ATE77744T1 (de) Verwendung von pyrrothinderivaten.
GR3022796T3 (en) Ureido-acetamide derivatives, preparation thereof and drugs containing same.
ATE206127T1 (de) Inhibitoren retroviraler proteasen

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 644873

Country of ref document: ES