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ES2100335T3 - Derivados de benzopirano y fenol para empleo como agentes inmunoestimulantes. - Google Patents

Derivados de benzopirano y fenol para empleo como agentes inmunoestimulantes.

Info

Publication number
ES2100335T3
ES2100335T3 ES92905459T ES92905459T ES2100335T3 ES 2100335 T3 ES2100335 T3 ES 2100335T3 ES 92905459 T ES92905459 T ES 92905459T ES 92905459 T ES92905459 T ES 92905459T ES 2100335 T3 ES2100335 T3 ES 2100335T3
Authority
ES
Spain
Prior art keywords
benzopyran
immuno
employment
phenol
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92905459T
Other languages
English (en)
Inventor
Maria Marconius
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2100335T3 publication Critical patent/ES2100335T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/322,3-Dihydro derivatives, e.g. flavanones
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A COMPUESTOS DE FORMULA GENERAL (I), DONDE R ES IDENTICO O DIFERENTE Y REPRESENTA H. OH O (A), PARA SU USO COMO AGENTE ANTIBACTERIANO, ANTIVIRAL O INMUNOESTIMULADOR O FACTOR DE CICATRIZACION DE HERIDAS. SE PRESENTA UN PROCESO PARA PREPARAR UNA MEZCLA QUE CONTIENE ESTAS SUSTANCIA, CON LO QUE UN PRODUCTO QUE CONTIENE PROPOLIS TAL COMO UN SOLVENTE ORGANICO, PREFERENTEMENTE UNA SOLUCION ALCOHOLICA QUE CONTIENE PROPOLIS, SE AÑADE AL AGUA O A UNA SOLUCION ACUOSA QUE CONTIENE 0,1% EN PESO DE NACL CON UNA TEMPERATURA DE 30-95 (GRADOS) C , Y LA MEZCLA SE MANTIENE A 30-95 (GRADOS) C DURANTE 100 HORAS, TRAS LO CUAL LA SOLUCION SE LIBERA DE LOS SEDIMENTOS DE FONDO. LA INVENCION SE REFIERE TAMBIEN A UNA COMPOSICION PARA USO HUMANO O VETERINARIO QUE CONTIENE AL MENOS UNA DE LAS SUSTANCIAS DE LA FORMULA (I) O PRODUCIDA CON EL PROCESO EN UN PORTADOR FARMACEUTICAMENTE ACEPTABLE.
ES92905459T 1991-02-15 1992-02-14 Derivados de benzopirano y fenol para empleo como agentes inmunoestimulantes. Expired - Lifetime ES2100335T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65680191A 1991-02-15 1991-02-15
US07/809,420 US5449794A (en) 1991-02-15 1991-12-17 Benzopyran phenol derivatives for use as antibacterial agents

Publications (1)

Publication Number Publication Date
ES2100335T3 true ES2100335T3 (es) 1997-06-16

Family

ID=27097268

Family Applications (2)

Application Number Title Priority Date Filing Date
ES95116380T Expired - Lifetime ES2171174T3 (es) 1991-02-15 1992-02-14 Derivados fenolicos de benzopirano para uso como agentes antibacterianos, antiviricos y de cicatrizacion de las heridas.
ES92905459T Expired - Lifetime ES2100335T3 (es) 1991-02-15 1992-02-14 Derivados de benzopirano y fenol para empleo como agentes inmunoestimulantes.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES95116380T Expired - Lifetime ES2171174T3 (es) 1991-02-15 1992-02-14 Derivados fenolicos de benzopirano para uso como agentes antibacterianos, antiviricos y de cicatrizacion de las heridas.

Country Status (11)

Country Link
US (1) US5449794A (es)
EP (2) EP0707851B1 (es)
JP (1) JP3682721B2 (es)
AT (2) ATE148341T1 (es)
AU (1) AU668348B2 (es)
CA (1) CA2104114C (es)
DE (2) DE69217206T2 (es)
DK (2) DK0707851T3 (es)
ES (2) ES2171174T3 (es)
NZ (1) NZ241633A (es)
WO (1) WO1992014458A1 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5861430A (en) * 1991-12-17 1999-01-19 Jasmine Fockerman Benzopyran phenol derivates for use as antibacterial, antiviral or immunostimulating agents
US8039026B1 (en) 1997-07-28 2011-10-18 Johnson & Johnson Consumer Companies, Inc Methods for treating skin pigmentation
DE19740879A1 (de) * 1997-09-17 1999-04-01 Beiersdorf Ag Desodorierende Zubereitungen auf der Basis von Flavonderivaten und/oder Flavanonderivaten, insbesondere von Flavonoiden
CN1293564A (zh) * 1998-03-16 2001-05-02 宝洁公司 调节皮肤外观的方法
DE19813802A1 (de) * 1998-03-27 1999-11-11 Retro Tech Gmbh Anti-virale Wirkung von Propolis durch Inhibition viraler Nukleinsäure Polymerasen
US8093293B2 (en) 1998-07-06 2012-01-10 Johnson & Johnson Consumer Companies, Inc. Methods for treating skin conditions
US8106094B2 (en) 1998-07-06 2012-01-31 Johnson & Johnson Consumer Companies, Inc. Compositions and methods for treating skin conditions
US6750229B2 (en) 1998-07-06 2004-06-15 Johnson & Johnson Consumer Companies, Inc. Methods for treating skin pigmentation
US6555523B1 (en) 1999-07-08 2003-04-29 Patrick T. Prendergast Use of cirsiliol and derivatives to treat infections
US7985404B1 (en) 1999-07-27 2011-07-26 Johnson & Johnson Consumer Companies, Inc. Reducing hair growth, hair follicle and hair shaft size and hair pigmentation
US7309688B2 (en) 2000-10-27 2007-12-18 Johnson & Johnson Consumer Companies Topical anti-cancer compositions and methods of use thereof
US8431550B2 (en) 2000-10-27 2013-04-30 Johnson & Johnson Consumer Companies, Inc. Topical anti-cancer compositions and methods of use thereof
BR0006272A (pt) * 2000-12-22 2002-08-13 Maria Cristina Marcucc Ribeiro Processo de identificação de tipagens da própolis brasileira
US6555143B2 (en) 2001-02-28 2003-04-29 Johnson & Johnson Consumer Products, Inc. Legume products
US7192615B2 (en) 2001-02-28 2007-03-20 J&J Consumer Companies, Inc. Compositions containing legume products
RU2185181C1 (ru) * 2001-03-05 2002-07-20 ООО "Тенториум" Способ получения водного экстракта прополиса эй-пи-ви
HU225388B1 (en) * 2001-05-31 2006-11-28 Viola Dr Szabo Rubber device for preventing infections and reducing spread of infections
US6803056B2 (en) * 2001-09-14 2004-10-12 Terence M. Dolak Method and composition for treating viral outbreaks
DE20306600U1 (de) * 2003-04-29 2003-09-04 Karpfl, Peter, 47546 Kalkar Hautpflegeprodukt bzw. Wundpflegemittel
MX390974B (es) * 2011-12-20 2025-03-13 Oriflame Cosmetics Ag Uso cosmético o dermatológico de naringenina para combatir efectos de envejecimiento de la piel.
CA3003757A1 (en) * 2015-11-05 2017-05-11 Universite Laval Compositions favoring wound repair
WO2021055506A1 (en) 2019-09-16 2021-03-25 Chemic Laboratories, Inc. Antimicrobial agents and compositions and uses thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1057349B (de) * 1955-12-31 1959-05-14 Emi Ltd Schallplatte mit herausnehmbarem und wiedereinsetzbarem Mittelteil und Verfahren zu ihrer Herstellung
AT320869B (de) * 1972-12-08 1975-03-10 Trommsdorff Fa H Verfahren zur Herstellung eines neuen Flavanonderivates
NZ193316A (en) * 1979-04-10 1984-07-31 Hoffmann La Roche 3-alkoxyflavone derivatives and pharmaceutical compositions
US4238483A (en) * 1979-07-19 1980-12-09 Frazier Stephen E Antimicrobial compositions of matter and a process for preparing antimicrobial compositions of matter from naturally occurring flavanoid glycosides
US4297348A (en) * 1980-04-11 1981-10-27 Rush-Hampton Industries, Inc. Composition and method for the treatment of acne
HU194855B (en) * 1983-02-16 1988-03-28 Alkaloida Vegyeszeti Gyar Process for producing chromene derivatives, insecticide and nematocide compositions containing chromene derivatives as active components
GB8321943D0 (en) * 1983-08-15 1983-09-14 Erba Farmitalia Preparation of 2,3-dihydro-benzopyranone derivatives
AU1708388A (en) * 1987-04-28 1988-12-02 University Patents Inc. Dihydroflavonol derivatives useful as sweeteners
SI8711835A8 (en) * 1987-10-05 1994-12-31 Ana Marija Mihelic Process for preparing a liquid ethanol extract of propolis
US4866080A (en) * 1988-01-13 1989-09-12 Buckman Laboratories International, Inc. Method for the control of mollusks
FR2633182B1 (fr) * 1988-06-23 1993-07-23 Beljanski Mirko Composition pharmaceutique anticancereuse et methode d'utilisation de l'invention
GB9201089D0 (en) * 1992-01-18 1992-03-11 Scient Generics Ltd A diagnostic article

Also Published As

Publication number Publication date
AU668348B2 (en) 1996-05-02
AU1277992A (en) 1992-09-15
DE69232338D1 (de) 2002-02-14
ATE148341T1 (de) 1997-02-15
DK0707851T3 (da) 2002-04-22
EP0571491B1 (en) 1997-01-29
US5449794A (en) 1995-09-12
EP0571491A1 (en) 1993-12-01
CA2104114A1 (en) 1992-08-16
DE69217206T2 (de) 1997-08-28
EP0707851B1 (en) 2002-01-09
ES2171174T3 (es) 2002-09-01
EP0707851A3 (en) 1998-04-01
JPH06508103A (ja) 1994-09-14
NZ241633A (en) 1994-06-27
EP0707851A2 (en) 1996-04-24
ATE211651T1 (de) 2002-01-15
CA2104114C (en) 2004-04-06
DE69217206D1 (de) 1997-03-13
DE69232338T2 (de) 2002-09-19
WO1992014458A1 (en) 1992-09-03
DK0571491T3 (da) 1997-08-11
JP3682721B2 (ja) 2005-08-10

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