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ES2195439T3 - Glicosidos de antraciclina. - Google Patents

Glicosidos de antraciclina.

Info

Publication number
ES2195439T3
ES2195439T3 ES98964472T ES98964472T ES2195439T3 ES 2195439 T3 ES2195439 T3 ES 2195439T3 ES 98964472 T ES98964472 T ES 98964472T ES 98964472 T ES98964472 T ES 98964472T ES 2195439 T3 ES2195439 T3 ES 2195439T3
Authority
ES
Spain
Prior art keywords
anthracicline
glycosids
formula
residues
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98964472T
Other languages
English (en)
Inventor
Cinzia Portello
Emanuele Arlandini
Umberto Breme
Anna Luisa Colombo
Giuliano Franchi
Giuliano Oronzo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Pharmacia Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Italia SpA filed Critical Pharmacia Italia SpA
Application granted granted Critical
Publication of ES2195439T3 publication Critical patent/ES2195439T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Los glicósidos de antraciclina de fórmula (I) *fórmula*, en la que R representa uno de los dos residuos (a) *fórmula* o (b) *fórmula*, y las sales farmacéuticamente aceptables de éstos son agentes antitumorales.
ES98964472T 1997-12-31 1998-11-27 Glicosidos de antraciclina. Expired - Lifetime ES2195439T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9727546.5A GB9727546D0 (en) 1997-12-31 1997-12-31 Anthracycline glycosides

Publications (1)

Publication Number Publication Date
ES2195439T3 true ES2195439T3 (es) 2003-12-01

Family

ID=10824351

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98964472T Expired - Lifetime ES2195439T3 (es) 1997-12-31 1998-11-27 Glicosidos de antraciclina.

Country Status (7)

Country Link
US (1) US6187758B1 (es)
EP (1) EP0970098B1 (es)
JP (1) JP2001515364A (es)
DE (1) DE69812077T2 (es)
ES (1) ES2195439T3 (es)
GB (1) GB9727546D0 (es)
WO (1) WO1999035153A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100540714B1 (ko) * 1997-11-28 2006-01-10 다이닛본 스미토모 세이야꾸 가부시끼가이샤 결정형 암루비신 염산염
GB0114654D0 (en) * 2001-06-15 2001-08-08 Pharmacia & Upjohn Spa Anti-tumor compound
GB0209467D0 (en) 2002-04-25 2002-06-05 Astrazeneca Ab Chemical compounds
RU2338537C2 (ru) * 2006-01-25 2008-11-20 Сергей Олегович Бачурин СРЕДСТВО ДЛЯ ЛЕЧЕНИЯ ШИЗОФРЕНИИ НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b)ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU33730B (en) * 1967-04-18 1978-02-28 Farmaceutici Italia Process for preparing a novel antibiotic substance and salts thereof
US4130535A (en) 1975-07-21 1978-12-19 Monsanto Company Thermoplastic vulcanizates of olefin rubber and polyolefin resin
JPS52148064A (en) 1976-05-31 1977-12-08 Microbial Chem Res Found Antitumors
US4077844A (en) * 1977-03-30 1978-03-07 The Upjohn Company Process for preparing steffimycinol
PL124284B1 (en) * 1979-10-17 1983-01-31 Politechnika Gdanska Process for preparing n-glycosyl derivatives of antibiotics from anthracyclines group
GB8606204D0 (en) 1986-03-13 1986-04-16 Erba Farmitalia Biosynthetic anthracyclines

Also Published As

Publication number Publication date
EP0970098B1 (en) 2003-03-12
EP0970098A1 (en) 2000-01-12
GB9727546D0 (en) 1998-03-18
DE69812077D1 (en) 2003-04-17
DE69812077T2 (de) 2003-12-18
JP2001515364A (ja) 2001-09-18
WO1999035153A1 (en) 1999-07-15
US6187758B1 (en) 2001-02-13

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