ES2194104T3 - Uso de selegilina para el tratamiento de la perdida de audicion en mamiferos. - Google Patents
Uso de selegilina para el tratamiento de la perdida de audicion en mamiferos.Info
- Publication number
- ES2194104T3 ES2194104T3 ES96917093T ES96917093T ES2194104T3 ES 2194104 T3 ES2194104 T3 ES 2194104T3 ES 96917093 T ES96917093 T ES 96917093T ES 96917093 T ES96917093 T ES 96917093T ES 2194104 T3 ES2194104 T3 ES 2194104T3
- Authority
- ES
- Spain
- Prior art keywords
- mammals
- hearing
- loss
- selegyline
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 241000124008 Mammalia Species 0.000 title abstract 2
- 208000016354 hearing loss disease Diseases 0.000 title abstract 2
- MEZLKOACVSPNER-GFCCVEGCSA-N selegiline Chemical compound C#CCN(C)[C@H](C)CC1=CC=CC=C1 MEZLKOACVSPNER-GFCCVEGCSA-N 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title abstract 2
- 241000282472 Canis lupus familiaris Species 0.000 abstract 1
- 206010011878 Deafness Diseases 0.000 abstract 1
- 230000010370 hearing loss Effects 0.000 abstract 1
- 231100000888 hearing loss Toxicity 0.000 abstract 1
- 229960003946 selegiline Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Abstract
SE UTILIZA LA SELEGILINA Y LAS FORMAS ANALOGAS FARMACEUTICAMENTE ACEPTABLES DE LA MISMA COMO TRATAMIENTOS PARA LA PERDIDA DE AUDICION EN MAMIFEROS, EN ESPECIAL PERROS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/475,186 US5561163A (en) | 1990-08-31 | 1995-06-07 | Treating hearing loss with deprenyl |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2194104T3 true ES2194104T3 (es) | 2003-11-16 |
Family
ID=23886552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES96917093T Expired - Lifetime ES2194104T3 (es) | 1995-06-07 | 1996-06-03 | Uso de selegilina para el tratamiento de la perdida de audicion en mamiferos. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5561163A (es) |
| EP (1) | EP0831798B1 (es) |
| JP (1) | JP3094305B2 (es) |
| AT (1) | ATE234614T1 (es) |
| AU (1) | AU693704B2 (es) |
| CA (1) | CA2221255C (es) |
| DE (1) | DE69626816T2 (es) |
| ES (1) | ES2194104T3 (es) |
| WO (1) | WO1996040094A1 (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005102345A1 (en) * | 2004-03-30 | 2005-11-03 | Alcon, Inc. | Use of rho kinase inhibitors in the treatment of hearing loss, tinnitus and improving body balance |
| JP4698671B2 (ja) | 2004-06-01 | 2011-06-08 | エフ.ホフマン−ラ ロシュ アーゲー | モノアミン再取り込み阻害剤としての3−アミノ−1−アリールプロピルインドール |
| CN105358677B (zh) | 2013-03-14 | 2018-06-15 | 布里格海姆妇女医院公司 | 用于上皮干细胞扩增和培养的组合物和方法 |
| KR102493376B1 (ko) | 2014-09-03 | 2023-01-27 | 더 브리검 앤드 우먼즈 하스피털, 인크. | 청력 손실의 치료를 위해 내이 털세포를 생성하기 위한 조성물, 시스템, 및 방법 |
| CA3010610A1 (en) | 2016-01-08 | 2017-07-13 | The Brigham And Women's Hospital, Inc. | Production of differentiated enteroendocrine cells and insulin producing cells |
| US10201540B2 (en) | 2016-03-02 | 2019-02-12 | Frequency Therapeutics, Inc. | Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using GSK3 inhibitors: I |
| US10213511B2 (en) | 2016-03-02 | 2019-02-26 | Frequency Therapeutics, Inc. | Thermoreversible compositions for administration of therapeutic agents |
| US11260130B2 (en) | 2016-03-02 | 2022-03-01 | Frequency Therapeutics, Inc. | Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using a GSK3 inhibitor: IV |
| CN110392686A (zh) | 2016-12-30 | 2019-10-29 | 频率治疗公司 | 1h-吡咯-2,5-二酮化合物以及使用它们来诱导干/祖支持细胞自我更新的方法 |
| US11617745B2 (en) | 2018-08-17 | 2023-04-04 | Frequency Therapeutics, Inc. | Compositions and methods for generating hair cells by downregulating FOXO |
| AU2019321641A1 (en) | 2018-08-17 | 2021-04-15 | Frequency Therapeutics, Inc. | Compositions and methods for generating hair cells by upregulating Jag-1 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA871155A (en) * | 1971-05-18 | Chinoin Gyogyszer-Es Vegyeszeti Termekek Gyara Rt | Optically active phenyl isopropylamine derivatives having pharmaceutical properties and their preparation | |
| HU187775B (en) * | 1982-07-14 | 1986-02-28 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu | New process for producing propargile-amines of pharmaceutical activity |
| HU193662B (en) * | 1983-12-20 | 1987-11-30 | Chinoin Gyogyszer Es Vegyeszet | Process for producing synergetic pharmaceutical composition of antidepressive aktivity |
| US4916151A (en) * | 1985-12-05 | 1990-04-10 | Merrell Dow Pharmaceuticals Inc. | Method of treating parkinson's syndrome |
| US4871550A (en) * | 1986-09-05 | 1989-10-03 | Millman Phillip L | Nutrient composition for athletes and method of making and using the same |
| US4861800A (en) * | 1987-08-18 | 1989-08-29 | Buyske Donald A | Method for administering the drug deprenyl so as to minimize the danger of side effects |
| US5192808A (en) * | 1990-08-31 | 1993-03-09 | Deprenyl Animal Health, Inc. | Therapeutic effect of L-deprenyl in the management of pituitary-dependent hyperadrenocorticism (cushing's disease) |
| CA2039194C (en) * | 1990-08-31 | 1997-01-28 | Norton W. Milgram | Uses of l-deprenyl and compositions for same |
| SE9301112D0 (sv) * | 1993-04-02 | 1993-04-02 | Orion-Yhtymae Oy | A new composition |
-
1995
- 1995-06-07 US US08/475,186 patent/US5561163A/en not_active Expired - Lifetime
-
1996
- 1996-06-03 CA CA002221255A patent/CA2221255C/en not_active Expired - Lifetime
- 1996-06-03 WO PCT/US1996/008642 patent/WO1996040094A1/en not_active Ceased
- 1996-06-03 AU AU59772/96A patent/AU693704B2/en not_active Ceased
- 1996-06-03 AT AT96917093T patent/ATE234614T1/de not_active IP Right Cessation
- 1996-06-03 ES ES96917093T patent/ES2194104T3/es not_active Expired - Lifetime
- 1996-06-03 DE DE69626816T patent/DE69626816T2/de not_active Expired - Fee Related
- 1996-06-03 EP EP96917093A patent/EP0831798B1/en not_active Expired - Lifetime
- 1996-06-03 JP JP09501174A patent/JP3094305B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP3094305B2 (ja) | 2000-10-03 |
| DE69626816T2 (de) | 2004-02-05 |
| EP0831798B1 (en) | 2003-03-19 |
| ATE234614T1 (de) | 2003-04-15 |
| CA2221255A1 (en) | 1996-12-19 |
| EP0831798A1 (en) | 1998-04-01 |
| JPH10510843A (ja) | 1998-10-20 |
| DE69626816D1 (de) | 2003-04-24 |
| CA2221255C (en) | 2005-11-08 |
| US5561163A (en) | 1996-10-01 |
| AU5977296A (en) | 1996-12-30 |
| AU693704B2 (en) | 1998-07-02 |
| WO1996040094A1 (en) | 1996-12-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BG100960A (bg) | Дозирани форми с контролирано освобождаване на азитромицин | |
| MX9700538A (es) | Uso de droloxifeno y sus sales farmaceuticamente aceptables en la preparacion de remedios para las enfermedades cardiovasculares. | |
| AR004357A1 (es) | Compuestos de 1-fenil-2-dimetilaminometil-ciclohexan-1-ol, y procedimiento de preparacion para dichos compuestos. | |
| FI956014A0 (fi) | Nona- ja dekapeptidien käyttö lääkkeen valmistamiseksi AIDS-sairauden hoitoon | |
| MX9705296A (es) | Compuestos novedosos de imidazol 1,4,5-susbtituidos y el uso de los mismos para preparar composiciones para uso en terapia. | |
| YU48666B (sh) | Mometason furoat monohidrat i postupak za njegovo dobijanje | |
| ES2154741T3 (es) | Uso de agentes de union a cd23 en el tratamiento de enfermedades autoinmunes. | |
| BR9814040A (pt) | Agudo no pulmão com fibrose com antagonistas de avb6 | |
| PT777482E (pt) | Composicao de combinacao para utilizacao em doencas imunologicas | |
| EE9700225A (et) | Meetod diabetes mellituse raviks, kasutades KKF | |
| AR016981A2 (es) | Polipeptidos sinteticos | |
| AR008799A1 (es) | Composicion de vacuna para prevenir o tratar el paludismo; uso de dicha composicion para elaborar medicamentos y metodo para dicha profilaxis y dichotratamiento | |
| CA2148988A1 (fr) | Utilisation d'extraits de bacteries filamenteuses comme agents cosmetiques contre le vieillissement cutane | |
| ES2063202T3 (es) | Nuevas 5,11-dihidro-6h-dipirido(3,2-b:2',3'-e)(1,4)diazepin-6-onas y -tionas y su uso en la prevencion o tratamiento del sida. | |
| ES2194104T3 (es) | Uso de selegilina para el tratamiento de la perdida de audicion en mamiferos. | |
| ES2167678T3 (es) | Tratamiento y profilaxis de la pancreatitis. | |
| TR199900505T2 (es) | ||
| ES2068714T3 (es) | Derivados de pirimidina para aumentar la actividad antitumoral. | |
| ES2066096T3 (es) | 4-bencil-5-fenil-2,4-dihidro-3h-1,2,4-triazol-3-onas y su uso como anticonvulsivos. | |
| ATE260559T1 (de) | Sordarinderivate | |
| BR0012006A (pt) | Método para evitar inflamações, doenças autoimunes e crescimento de tumor, e, uso de substâncias que suprimem a ativação mediada por ltbr | |
| ES2058349T3 (es) | Utilizacion de betabloqueadores para el tratamiento de la progresion de la miopia axial infantil. | |
| ES2196769T3 (es) | Uso topico de loperamide para el tratamiento de infecciones microbianas. | |
| ES2171080T3 (es) | Composicion para la mejora de la fertilidad y su aplicacion. | |
| MXPA01012495A (es) | Metodo para tratar la perdida capilar con el uso de derivados de difenilmetano. |